Jacob L. Stubbs

Jacob L. Stubbs
University of British Columbia - Vancouver | UBC · Department of Psychiatry

BKin

About

31
Publications
8,765
Reads
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3,102
Citations
Introduction
PhD Candidate, UBC Department of Psychiatry (2018 - Present) | Co-supervised by Dr. William J. Panenka and Dr. William G. Honer
Education
January 2022 - September 2022
Harvard University
Field of study
  • Advanced network neuroimaging
September 2018 - May 2023
University of British Columbia - Vancouver
Field of study
  • Experimental Medicine
September 2014 - May 2018

Publications

Publications (31)
Article
Cavities in the hippocampus are morphological variants of uncertain significance. Aberrant neurodevelopment along with vascular and inflammatory etiologies have been proposed. We sought to characterize these cavities and their potential risk factors in a marginally housed population, with high rates of viral infection, addiction, and mental illness...
Article
Full-text available
Background Homeless and precarious housed persons are particularly prone to traumatic brain injuries (TBIs), but existent incidence rates are hampered by poor case acquisition. We rigorously documented TBIs in precariously housed persons transitioning in and out of homelessness. Methods Between December 2016 and May 2018, 326 precariously housed...
Article
Full-text available
Background: Homeless and precarious housed persons are particularly prone to traumatic brain injuries (TBIs), but existent incidence rates are hampered by poor case acquisition. We rigorously documented TBIs in precariously housed persons transitioning in and out of homelessness. Methods: Between December 2016 and May 2018, 326 precariously housed...
Preprint
Full-text available
Importance Homeless or precariously housed individuals live with poor health and experience premature mortality compared to the general population. With an increasing average age among this demographic, syndromes associated with neurogenerative disease are also increasing. Quantitative MRI measures may help define the roles of age and risk factors...
Article
Background opioid use, which includes both prescribed and non-prescribed drugs, is relatively common amongst marginalized populations. Past research has shown that among those who use non-prescribed or diverted opioids recreationally, many were first exposed to the drug as prescribed pain medication. Objective: to better understand the relationship...
Article
Objective: Traumatic brain injury (TBI) is increasingly recognized as a common and impactful health determinant in homeless and precariously housed populations. We sought to describe the history of TBI in a precariously housed sample and evaluate how TBI was associated with the initial loss and lifetime duration of homelessness and precarious hous...
Article
Objective: Somatization is thought to underlie functional somatic syndromes (FSSs) and may also contribute to prolonged symptoms after mild traumatic brain injury (mTBI). The investigators evaluated the prevalence of FSSs in patients seeking specialty care after mTBI and whether a history of FSSs was associated with symptom persistence. Methods:...
Article
Full-text available
Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of...
Article
Full-text available
Summary Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a sta...
Article
Full-text available
Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publ...
Article
Full-text available
Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of...
Article
Full-text available
Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardise...
Article
Longitudinal studies of cannabis exposure during early adolescence in the general population frequently report an increased risk of subsequently developing psychotic symptoms or a psychotic illness. However, there is a dearth of knowledge about the effects of early cannabis exposure on psychosis in homeless and precariously housed adults, who repre...
Article
Full-text available
Somatization may contribute to persistent symptoms after mild traumatic brain injury (mTBI). In two independently-recruited study samples, we characterized the extent to which symptoms atypical of mTBI but typical for patients suffering from somatization (e.g., gastrointestinal upset, musculoskeletal, and cardiorespiratory complaints) were present...
Article
Full-text available
Background: Homelessness is a global public health concern, and traumatic brain injury (TBI) could represent an underappreciated factor in the health trajectories of homeless and marginally housed individuals. We aimed to evaluate the lifetime prevalence of TBI in this population, and to summarise findings on TBI incidence and the association betwe...
Preprint
Full-text available
We characterized the prevalence, mechanisms, and sex difference of lifetime traumatic brain injury (TBI) in a precariously housed sample. We also examined the impact of TBI severity and timing on becoming and staying homeless. 285 precariously housed participants (adults n = 226, youths n = 59) completed the Brain Injury Screening Questionnaire (BI...
Preprint
Full-text available
Somatization may contribute to persistent symptoms after mild traumatic brain injury (mTBI). In two independently-recruited study samples, we characterized the extent to which symptoms atypical of mTBI but typical for somatoform disorders (e.g., gastrointestinal upset, joint pain) were present in adult patients with prolonged recovery following mTB...
Article
Introduction: Clinical evidence suggests that Parkinson's Disease (PD) patients are risk averse. Dopaminergic therapy has been reported to increase risk tolerance, but the underlying mechanisms are unclear. Some studies have suggested an amplification of subjective reward value, consistent with the role of dopamine in reward value coding. Others h...
Preprint
Full-text available
Background Acquired prosopagnosia is often associated with other deficits, such as dyschromatopsia and topographagnosia, from damage to adjacent perceptual networks. A recent study showed that some subjects with developmental prosopagnosia also have congenital amusia, but problems with music perception have not been described in the acquired varian...
Preprint
Introduction Clinical evidence suggests that Parkinson’s Disease (PD) patients are risk averse. Dopaminergic therapy has been reported to increase risk tolerance, but the underlying mechanisms are unclear. Some studies have suggested an amplification of subjective reward value, consistent with the role of dopamine in reward value coding. Others hav...
Article
Full-text available
Mr Ronnie Grigg has been a long-time harm reduction worker in the Vancouver Downtown Eastside and is currently general manager of the Vancouver Overdose Prevention Society. Located at 58 East Hastings St. in Vancouver, British Columbia, the Vancouver Overdose Prevention Society is a not-for-profit organization that oversees hundreds of consumptions...
Article
Studies of developmental prosopagnosia have often shown that developmental prosopagnosia differentially affects human face processing over non-face object processing. However, little consideration has been given to whether this condition is associated with perceptual or sensorimotor impairments in other modalities. Comorbidities have played a role...
Article
Full-text available
Smooth pursuit eye movements have been investigated as a diagnostic tool for mild traumatic brain injury (mTBI). However, the degree to which smooth pursuit differentiates mTBI patients from healthy controls (i.e. its diagnostic performance) is only moderate. Our goal was to establish if simultaneous performance of smooth pursuit and a working memo...
Article
Full-text available
The Centers for Disease Control and Prevention considers mild traumatic brain injury (mTBI), commonly known as concussion, a genuine public health issue. Emerging research is revealing serious long–term sequelae from repeated concussive blows, yet no single test can defnitively diagnose mTBI. Pediatric brains are more sensitive to injury, lending a...
Article
Full-text available
It has long been suggested that increasing attentional demands can alter smooth pursuit eye movements, but the precise nature of the changes generated is not clear. Our goal was to examine smooth pursuit with a task that enhanced attention to the target and that increased demands on working memory, without distracting from the target. 15 subjects t...

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Projects

Projects (2)
Project
To improve the diagnostic performance of smooth pursuit eye movement as a diagnostic tool for mild traumatic brain injury