Jackson Jr Nforbewing NdenkehYale University | YU · School of Nursing - Research
Jackson Jr Nforbewing Ndenkeh
PhD in Medical Research
About
43
Publications
12,417
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Citations
Introduction
Ndenkeh does research in Epidemiology, Global Health and Implementation Science.
Education
October 2018 - September 2023
January 2013 - July 2015
October 2009 - July 2012
Publications
Publications (43)
Adolescent girls and young women (AGYW) are vulnerable populations to HIV/AIDS. We conducted a cross-sectional survey among 637 AGYW in Cameroon to study the feasibility and willingness to use mobile applications (apps) for HIV testing, prevention, and treatment. We found that phone ownership is high among AGYW, where 93.9% ( n = 598) of them (medi...
OBJECTIVE
To determine the social impact of adult TB on child household contacts living in the Greater Banjul Area, The Gambia.
METHODS
This was a prospective observational cohort study among adults (≥18 years) starting treatment for drug-susceptible pulmonary TB between June 2019 and July 2021 who reported having at least one child household cont...
Introduction
The pediatric HIV treatment coverage in Cameroon remains low at 35%. The high loss to follow up (LTFU) remains a major factor to this dismal performance which is related to the lack of implementation of effective interventions to improve retention in care. This study assessed the impact of foods support (FS) on LTFU among children and...
Background:
Several interventions have shown benefits in improving mental health problems such as depression which is common in people living with HIV. However, there is a paucity of evidence on the effect of these interventions in improving HIV treatment outcomes. This study aimed at bridging this evidence gap and guiding the integration of depre...
Adolescents and sexual minority men (SMM) are high priority groups in the United Nations’ 2021 − 2016 goals for HIV prevention and viral load suppression. Interventions aimed at optimizing HIV prevention, testing and viral load suppression for adolescents must also attend to the intersectional realities influencing key sub-populations of SMM. Conse...
Having reliable data on the performance of different parts of the health system is the only way to devise, execute, and measure health interventions. In Cameroon, the National Health Information System (NHIS) is sub-optimal and faces a considerate number of shortcomings. This system which consists of data collection, processing, reporting, and use...
Introduction:
Pre-exposure prophylaxis (PrEP) is proven to be a highly effective HIV prevention method for key populations. However, its scale-up in resource-limited settings remains sub-optimal. This paper seeks to describe PrEP initiation and continuation among key populations in Cameroon.
Methodology:
From June 2019 through October 2020, we c...
Flaviviruses are a family of viruses that cause many diseases in humans. Their similarity in the antigenic structure causes a cross-reaction, which complicates the precise diagnostic of disease causing agents. Tick-borne encephalitis virus (TBEV), a member of the flavivirus family, is the cause of tick-borne encephalitis (TBE). Worldwide the awaren...
While pediatric human immunodeficiency virus (HIV) testing has been more focused on children below 18 months through prevention of mother to child transmission of HIV (PMTCT), the yield of this approach remains unclear comparatively to testing children above 18 months through routine provider-initiated testing and counselling (PITC). This study aim...
p class="abstract"> Background: Excessive gestational weight gain (EGWG) during pregnancy can lead to adverse outcomes for the mother and/or the new-born. The aim of the study was to determine the prevalence of EGWG as well as its effect on pregnancy outcomes amongst pregnant women at the health district of Dschang in Cameroon.
Methods: This was a...
Background
Cervical cancer is a leading cause of death among Cameroon women. The burden of cervical cancer is in part traceable to the inadequate understanding of socio-contextual determinants of access to screening and prevention opportunities. We explored multilevel individual, community and structural factors that facilitate or inhibit cervical...
Electronic Health (eHealth) is the use of information and communication technologies for health and plays a significant role in improving public health. The rapid expansion and development of eHealth initiatives allow researchers and healthcare providers to connect more effectively with patients. The aim of the CIHLMU Symposium 2020 was to discuss...
Background: Achieving an AIDS-free generation requires effective pediatric testing and treatment services. While pediatric HIV testing has been more focused on children below 18 months through PMTCT, the yield of this approach remains unclear comparatively to testing children above 18 months through routine PITC. This study aimed at bridging this e...
Objectives
The number needed to test (NNT) to identify a child infected with HIV remains high in the context of the implementation of the blanket provider-initiated testing and counselling (bPITC) strategy. This study assessed the predictors of HIV seropositivity among outpatient children/adolescents (6 weeks-19 years) in Cameroon. This information...
Background
There is a growing body of evidence positioning targeted provider-initiated testing and counselling (tPITC, also known as index case testing) as a promising HIV case-finding and linkage strategy among children and adolescents. However, the effectiveness and efficiency of this strategy is limited by low HIV testing uptake and case detecti...
Introduction. Tetanus vaccination plays an important role in the fight against neonatal mortality. Our study aimed to determine
the noncompletion rate of the 3rd dose of tetanus toxoid vaccine (TTV) and to analyze the associated factors in pregnant women.
Methods. +is was a cross-sectional study conducted in 2 hospitals of Dschang Health District a...
Background
Cervical cancer is a leading cause of death among Cameroon women. The burden of cervical cancer is in part traceable to the inadequate understanding of contextual determinants of access to expanding screening and prevention opportunities. We explored multilevel individual, community and structural factors that facilitate or inhibit cervi...
Introduction: The size of the elderly population continues to increase rapidly in developing countries. Unfortunately, these countries are often least prepared to meet the health challenges of rapidly ageing population. The old are characterized by chronic non-communicable disease burden and disability, thus requiring opportunities for regular heal...
Objectives
The concurrent implementation of targeted (tPITC) and blanket provider-initiated testing and counselling (bPITC) is recommended by the World Health Organization (WHO) for HIV case-finding in generalized HIV epidemics. This study assessed the effectiveness of this intervention compared to symptom-based diagnostic HIV testing (DHT) in term...
Structured Form.OPDs.
(DOCX)
Outcomes of 6-month implementation of DHT versus bPITC+tPITC.
(DOCX)
Structured Form.ART Clinics.
(DOCX)
Pediatric vaccination against Hepatitis B Virus (HBV) leads to the induction of immunoglobulin G (IgG) antibodies specific to hepatitis B surface antigen (anti-HBs) consisting of four IgG subclasses. In the context of potential immuno-suppression arising from neonatal infection with the Immunodeficiency virus type one (HIV) an analyses of the anti-...
Africa is experiencing an increase in the burden of chronic non-communicable diseases notably diseases like hypertension, diabetes and cancers. Female cancers in Sub Saharan Africa are the leading causes of cancer-related morbidity and mortality with most vulnerable population women at the age of procreation.These women on the other hand have a rea...
Despite the prevalence of malnutrition in developing countries, it is rarely given the attention it deserves as one of the leading cause of infant morbido-mortality. Rather diseases like diarrheal diseases, malaria and other communicable diseases are given more attention while forgetting the underlying role of malnutrition in the deterioration of t...
In developing countries access to Primary Health Care services is still yet to be optimal. A considerate part of the population still finds it very difficult to come across the quality health care services they need. Here we try to bring out the various internal and external factors that lead to the above problem and how these factors can be addres...
Malnutrition still remains a major public health problem in Cameroon affecting mostly the Northern and Eastern regions of the country. Despite the interventions put in place by the government and other stake holders to eradicate poverty and ameliorate food security the problem still endures with severity changing with respect to space and time. Thi...
Introduction: Hemiplegia is the first cause of physical and mental handicap in adults with an incidence of 1.5 per 1000. Death arises principally during the first six months; the mortality rate is estimated at 25% for the first month. There are many rehabilitative methods for this handicap but this research was focused on the Proprioceptive Neuromu...
Background: Street children are victims of society and are up to 10 - 25 times more vulnerable and affected by
HIV/AIDS than their counterparts who live with their families. Objective of study: To examine the HIV/AIDS-related
knowledge, attitudes and sexual experience amongst street children in Cameroon.
Methods: This study was an analytical cross-...
Background: Street children are victims of society and are up to 10 - 25 times more vulnerable and affected by
HIV/AIDS than their counterparts who live with their families. Objective of study: To examine the HIV/AIDS-related
knowledge, attitudes and sexual experience amongst street children in Cameroon.
Methods: This study was an analytical cross-...
Though the world health assembly passed a resolution to " eliminate leprosy as a public health problem " by 2000, the disease is still common in many countries worldwide. Leprosy deforms and disables but seldom kills so that those who have been crippled live on getting steadily worse. Thus, the researcher was prompted to explore the lived experienc...
Abdominal pathologies pose serious health problems as many are associated with complications. Plain AXRs and
Ultrasound are widely used for diagnosis. The use of plain abdominal x-rays has been greatly criticized. It is against such
criticisms that this cross sectional and retrospective study was aimed at comparing the use of the above mentioned im...
Lung cancer is a big threat to health in the world but many people are still unaware of this fact. The American
cancer society has classified lung cancer as the most deadly cancer in both men and women in the world. This study was thus
implemented with the objective to assess the knowledge of the inhabitants of Ngeme on lung cancer, its predisposin...
Maggot therapy (MT) is a type of therapy in which live, disinfected maggots cultured in a sterile manner is
placed into a non-healing skin and soft tissue wound of humans to clean out the necrotic tissue within a wound and to
disinfect it. This therapy has been used for centuries for treatment of non-healing soft tissue wounds until the arrival of...
The HIV-1 envelope glycoprotein gp120 is a potential immunogen for the induction of broadly neutralizing antibodies. However the recombinant envelope glycoprotein gp120 (WT) generated for vaccine trials differs markedly from the native viral envelope glycoprotein which is predominantly composed of oligomannose antigens (i.e. antigens glycosylated w...
Keywords: PMTCT, HBV vaccine, IgG subclass
Despite the numerous interventions for the amelioration of socio-economic status and food security in Africa, the output still does not show any significant effect, leaving people to wonder if it will ever be possible to eradicate poverty and malnutrition in that part of the world. Malnutrition can effectively be eradicated but it will all depend o...
The entry of HIV-1 into its target cell is mediated by an interaction between the gp120 of the virus and host cell receptors. Specific antibodies to the HIV-1 gp120 can be of enormous help in preventing or blocking this interaction. However stimulation of these neutralizing antibodies has proven difficult to achieve through vaccination because of t...
Evaluating plasmatic biomarkers as disease signatures for the point of care monitoring of HIV-1 and comorbidities in resource limited regions.
Questions
Question (1)
I am doing an analysis of data collected in an intervention study seeking to improve antiretroviral treatment adherence using depression management (using a package of defined strategies ranging from psychoeducation, interpersonal psychotherapy, and pharmacotherapy depending on depression severity). My baseline data showed depression score to be significantly correlated to ART adherence score as well as major depression (when adjusted for other covariates) to be significantly associated with poor adherence. Also, for those who had depression or minimal symptoms (in a per-protocol analysis), the intervention significantly dropped their depression scores compared to controls. Now I want to get the real effect of this change in the depression on their change in adherence to treatment i.e. adjusting for the other covariates in the regression model at baseline. I have two questions; Is this the right approach to this analysis? If yes, how do I proceed in getting the change in adherence adjusted for the other covariates used in the model at baseline?
