Iván Neira

• Dr.
• Professor (Associate) at University of Antofagasta

The Mapuche and their ancestors have used Drimys winteri in traditional medicine. In the present study, the essential oil extract of Drimys winteri leaves (DW_EO) were characterized chemically and biologically to evaluate its pharmacological activity. In vitro antioxidant activity was assayed, and antitumor activity was evaluated in non-tumor and t...

Chilean Laureliopsis philippiana has been used in traditional medicine by the Mapuche and their ancestors. To evaluate its pharmacological activity, Laureliopsis philippiana leaf essential oil extract (LP_EO) was chemically and biologically characterized in the present study. In vitro antioxidant potential was analyzed, and antitumor activity was e...

Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential oils were extracted using hydrodistillation in Clevenger apparatus and analyzed by GC-MS to determine their composition. The antiox...

The interest of the food industry in replacing artificial dyes with natural pigments has grown recently. Cyanobacterial phycobiliproteins (PBPs), phycoerythrin (PE) and phycocyanin (PC), are colored water-soluble proteins that are used as natural pigments. Additionally, red PE and blue PC have antioxidant capabilities. We have formulated a new food...

Acantholippia deserticola (Rica rica; RR) and Artemisia copa (Copa copa; CC) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Atacameños people. The essential oils were analized by GC/MS, the principal compounds found in RR essential oil (RR_EO) were β-thujone (45%), β-linalool (16%), and eucal...

Alzheimer's disease and inclusion body myositis (IBM) are disorders frequently found in the elderly and characterized by the presence of amyloid-β peptide (Aβ) aggregates. We used Caenorhabditis elegans that express Aβ in muscle cells as a model of IBM, with the aim of analyzing Aβ-induced muscle pathology and evaluating the consequences of modulat...

Diphyllobothriosis is a zoonosis related to the consumption of crude or inadequately cooked sea or freshwater fish. We report a case of diphyllobothriosis caused by D. pacificum diagnosed in a 3 year old boy in the city port of Antofagasta in the north of Chile. The patient expelled one strobile of 55cm from which a morphometric study of proglotids...