Iúri Drumond Louro

Iúri Drumond Louro
Federal University of Espírito Santo | UFES · Departamento de Ciências Biológicas

M.D., Ph.D.

About

236
Publications
26,152
Reads
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1,923
Citations
Additional affiliations
August 2002 - present
Federal University of Espírito Santo
Position
  • Research Director
August 2002 - present
Federal University of Espírito Santo
Position
  • Professor Associado 2 at Universidade Federal do Espírito Santo, Brazil.
Description
  • Genética Molecular de Doenças Humanas. Identificação Genética. Genética de Doenças Infecciosas.
August 1994 - August 2002
University of Alabama at Birmingham
Position
  • PhD & Posdoc at University of Alabama at Birmingham, USA.
Description
  • Cancer Genetics. We have studied the GLI oncogene and its sensibility to rapamycin treatment in cell culture. Expression analysis with Affymetrix microarrays.

Publications

Publications (236)
Article
Full-text available
Após o período de infecção pelo SARS-CoV-2, constatou-se o aumento de indivíduos com diversos sintomas multissistêmicos persistentes por semanas ou meses. Entre as sequelas, destacam-se os impactos neurológicos, em especial a depressão e ansiedade. Assim, torna-se necessário investigar os componentes genéticos que contribuem nos transtornos depress...
Article
Full-text available
Brazil is the world leader in pesticide consumption, and its indiscriminate use puts farmers’ health at risk. The CYP2C9 gene encodes the CYP2C9 enzyme, which metabolizes several endogenous substrates and specific xenobiotics, especially pesticides. Our goal is to study the risk of pesticide use, especially the herbicide glyphosate, in the developm...
Article
Full-text available
The pan-cancer and multi-omics approach is motivated by the genetic and molecular complexity inherent in the varied types of cancer. This method presents itself as a crucial resource for advancing early diagnosis, defining prognoses and identifying treatments that share common bases between different forms of tumors. The aim of this article is to e...
Article
Twenty-first century trends indicate that the central characteristic of contemporary education is the shift from an individual focus to a social, political, and ideological focus. Active teaching–learning methodologies, particularly with a problematizing approach, have been used in training and health professionals, as a strategy aimed at integrati...
Article
Full-text available
Chikungunya patients may develop chronic joint pain that can persist for months to years. This study aimed to determine the factors associated with Chikungunya chronicity. This case–control study involved data from patients with laboratory-confirmed Chikungunya reported from March 2016 to December 2020 in Vitória, Espírito Santo state, Brazil. The...
Article
Full-text available
Cancer therapy is facing increasingly significant challenges, marked by a wide range of techniques and research efforts centered around somatic mutations, precision oncology, and the vast amount of big data. Despite this abundance of information, the quest to cure cancer often seems more elusive, with the “war on cancer” yet to deliver a definitive...
Preprint
Full-text available
Brazil is the world leader in pesticide consumption, and its indiscriminate use puts farmers’ health at risk. The CYP2C9 gene stands out for encoding the CYP2C9 enzyme, which metabolizes several endogenous substrates and specific xenobiotics, especially pesticides. Our goal is to study the risk of pesticide use, espe-cially the herbicide glyphosate...
Poster
Full-text available
Palavra-chave 1: Single-Cell Tracking Palavra-chave 2: Glioblastoma Palavra-chave 3: Ploidy Variation Palavra-chave 4: Tumor Resistance Palavra-chave 5: CellProfiler
Poster
Full-text available
Palavra-chave 1: Computational Biology Palavra-chave 2: Systems Biology Palavra-chave 3: Single Cell Biology Palavra-chave 4: Oncology Palavra-chave 5: Network Biology
Article
Full-text available
Since December 2019, a new form of Severe Acute Respiratory Syndrome (SARS) has emerged worldwide, caused by SARS coronavirus 2 (SARS-CoV-2). This disease was called COVID-19 and was declared a pandemic by the World Health Organization in March 2020. Symptoms can vary from a common cold to severe pneumonia, hypoxemia, respiratory distress, and deat...
Article
Full-text available
Biotechnology constitutes a realm of inquiry that extends its benefits across diverse domains of knowledge, ranging from agricultural sciences to clinical applications. This field leverages technology to address challenges frequently entailing living organisms. Of current significance is the endeavor to elucidate the process of animal regeneration,...
Article
Full-text available
O câncer/neoplasias de mama (CM) é uma doença altamente incidente em mulheres com milhões de novos casos a cada ano. Dentre os avanços tecnológicos destaca-se a tecnologia de RNA-seq que permitiu compreender melhor a expressão gênica, possibilitando desvendar as interações proteicas entre tumores de mama em estágio inicial e recorrente (pós-mastect...
Article
Full-text available
Glycosylation is the most common protein and lipid post-translational modification in humans. Congenital disorders of glycosylation (CDG) are characterized by both genetic and clinical heterogeneity, presenting multisystemic manifestations, and in most cases are autosomal recessive in inheritance. The PIGN gene is responsible for the addition of ph...
Poster
Full-text available
Polyploid/Multinucleated giant cancer cells (PGCCs/MNGCs) represent subpopulations of cancer cell relevant for tumor evolution and adaptation to therapeutic stress. PGCCs/MNGCs are characterized by nuclear alterations including micronucleation, multinucleation and nuclear enlargement. Understand the PGCCs/MNGCs phenotype in glioblastoma (GB), we em...
Article
Full-text available
Biotechnology is the term given to the branch of science that employs knowledge, techniques, and genetic engineering methods for creating various products using living organisms as raw material. Although this term has been recently adopted, humans have long been manipulating biological processes for their own benefit. Biotechnology is multidiscipli...
Article
Full-text available
Objective Determine characteristics associated with hospitalization in the acute phase of Chikungunya. Methods Cross-sectional study including data on Chikungunya cases reported in Vitória, Espírito Santo state, Brazil, between March 2016 and December 2021. Results Hospitalizations accounted for 1.42% (n = 41) of the 2,868 cases included. There w...
Article
Full-text available
O farmacêutico oncológico clínico tem um importante papel no manejo farmacoterapêutico de pacientes que realizam quimioterapia. Atualmente, este profissional faz uso de alguns métodos para facilitar o emprego do Acompanhamento Farmacoterapêutico em Oncologia, como o Método Dáder. A Inteligência Artificial surge como uma nova ferramenta para auxilia...
Article
Full-text available
O Transtorno de Ansiedade Generalizada (TAG) é um distúrbio mental caracterizado por preocupações excessivas e persistentes, juntamente com sintomas físicos e cognitivos. Para melhor entender seu impacto na pandemia de COVID-19, este estudo empregou a pesquisa bibliográfica em bases de dados, buscando artigos que investigaram os efeitos da pandemia...