Itishree JOGAMAYA Das

Birla Institute of Technology, Mesra | BIT Mesra · Department of Pharmaceutical Sciences

The Coconut Shell Fillers (CSF) loaded with different wt% (10, 20, 30, 40, and 50) and reinforced with a single layer of Pine Apple Fibre Mat (PAFM) epoxy sandwich polymer composites were fabricated through closed mold hand layup techniques. The sandwich composite specimens were carried out the mechanical characterization and found the maximum tens...

Breast cancer (BC) is the second most prevalent cancer among women and can originate from the tubes, connective tissue, and lobules of the breast. The primary focus of this review is to highlight the significant advancement in the development of receptor-targeted nanotherapy for the management of metastatic breast cancer. These innovative systems d...

Bioimplants for the body are designed to mimic and support the body tissues for their easy replication which necessitates them to behave like extracellular matrix and be biologically inert for provoking minimal tissue response. But this concept is modified nowadays, as implants for biomedical applications demands tremendous mechanical resistance to...

Objective The majority of new chemical substances generated by the drug development process are poorly water-soluble or lipophilic. Formulation of a poorly water-soluble substance is a difficult task for the pharmaceutical industry. It is widely acknowledged that using nanosuspension in drug administration enhances the drug’s solubility, dissolutio...

Periodontitis is a group of inflammatory diseases which results the destruction of tooth-supporting tissues and affects 20-50% of the global population. Different bacterial enzymes are released into the periodontal pockets as a result of the proliferation of varied microflora, particularly anaerobes, which affect the body's immune response. A key c...

Once a dye, curcumin (CUR) has transformed into a versatile therapeutic agent with antioxidative, anti-inflammatory, and anticancer properties. Despite its potent anticancer effects, CUR encounters challenges such as poor solubility and a short circulation half-life. To address this, researchers utilize nanocarriers like nanoparticles, liposomes, a...

Stimuli-sensitive superporous hydrogels prepared using natural polymers are efficient in sustaining structural integrity for an extended duration and can be employed as an effective drug delivery system including polymeric scaffold for tissue regeneration. A pH-sensitive superporous hydrogel was designed by blending two natural polysaccharides Opun...

The human body is composed of many vital elements and phosphorus is one such element that forms the basic ingredient of our biological constitution. Recently, researchers are more lenient on fabricating and applying materials for biomedical applications which pose the least threat to the human body with high mechanical strength and degradability op...

Periodontitis is one of the most widespread oral inflammatory infectious diseases affecting the oral cavity. This study aims to develop and characterize a more effective syringeable curcumin in situ gel for the treatment of periodontitis and evaluate its clinical effectiveness. Curcumin in situ gel was formulated by the cold method using temperatur...

Periodontitis is one of the most widespread oral inflammatory infectious diseases affecting the oral cavity. This study aims to develop and characterize a more effective syringeable curcumin in situ gel for the treatment of periodontitis and evaluate its clinical effectiveness. Curcumin in situ gel was formulated by the cold method using temperatur...

Periodontitis describes a group of related inflammatory diseases resulting in the destruction of the tissues that support the tooth. This disease results from the growth of diverse microflora (especially anaerobes) in the periodontal pockets and releases various bacterial enzymes, toxins, and stimulation of the body’s immune response. Scaling and R...

Background: Periodontitis is one of the most widespread oral diseases. Curcumin, a hydrophobic polyphenolic compound derived from the rhizomes of Curcuma longa has a great potential for biological and pharmacological activities. The introduction of local controlled delivery of curcumin directly into the periodontal pocket is a promising approach fo...

Th e a i m o f th e p r e se n t s t ud y w a s t o f o r m ul a t e , E v a l u a te a n d o p t i m i z e f a s t dissolving tablets of Glimepiride. Glimepiride is a Third generation sulphonylureas used for the treatment of type-2 diabetes and belongs to BCS class II drugs (Low Solubility and High Permeability). Glimepiride was the drug of choice...

Aim: The objective of this research was to design and evaluate dental film containing curcumin for the topical treatment of periodontal diseases. Materials and Methods: Curcumin, hydrophobic polyphenolic compounds derived from the rhizomes of Curcuma longa, shows wide spectrum of antibacterial, anti-inflammatory, and antioxidant properties activity...

Aim: To design and characterize oral controlled release matrix tablets of lamivudine to improve efficacy and patient compliance. Materials and Methods: Lamivudine matrix tablets were prepared by wet granulation method using various proportions of hydrophilic polymers such as sodium carboxymethylcellulose (Na CMC), hydroxypropyl methylcellulose (HPM...

The present study involves the design and characterization of floating microspheres with gabapentin as model drug for prolongation of gastric residence time. Gabapentin floating microspheres were prepared by o/w/o emulsification solvent diffusion technique using ethyl cellulose as the rate controlling polymer at various concentrations. The shape an...

The aim of the present study was to formulate, Evaluate and optimize fast dissolving tablets of Glimepiride. Glimepiride is a Third generation sulphonylureas used for the treatment of type-2 diabetes and belongs to BCS class II drugs (Low Solubility and High Permeability). Glimepiride was the drug of choice because of its low dose. Glimepiride fast...

The objective of the present investigation was to study the influence of Superdisintegrants like sodium starch glycolate (SSG), croscarmelose sodium (CCS), crospovidone (CP), Physical mixture of Superdisintegrants and Co process superdisintegrants as dissolution enhancer on in-vitro dissolution in a model formulation and their different mode of inc...