Istvan Urban

Istvan Urban
University of Michigan | U-M · Department of Periodontics and Oral Medicine

DMD, MD, PhD

About

63
Publications
97,527
Reads
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1,702
Citations
Citations since 2016
44 Research Items
1473 Citations
20162017201820192020202120220100200300
20162017201820192020202120220100200300
20162017201820192020202120220100200300
20162017201820192020202120220100200300
Additional affiliations
June 2001 - present
Loma Linda University
Position
  • Professor (Assistant)

Publications

Publications (63)
Article
Severe alveolar ridge deficiencies in concomitance with periodontal attachment loss can represent a serious clinical challenge in the context of implant therapy. The present case report describes the management of a complex defect in the esthetic zone via ridge augmentation and periodontal regenerative therapy using a biologic material. A systemica...
Article
The cover image is based on the Research Article Horizontal guided bone regeneration on knife‐edge ridges: A retrospective case‐control pilot study comparing two surgical techniques by Helene Arnal et al., https://doi.org/10.1111/cid.13073. The cover image is based on the Research Article Horizontal guided bone regeneration on knife‐edge ridges: A...
Article
Full-text available
Introduction: Studies evaluating guided bone regeneration (GBR) on knife-edge ridges using absorbable membranes with staged approaches have reported various horizontal bone gains. This study compared the horizontal bone gain obtained via a conventional technique of GBR and a recently-reported technique. Bone loss during the healing process was als...
Article
Full-text available
Background: Esthetic complications of dental implants in the esthetic zone can have a major negative impact on patients' quality of life and perception of implant therapy. The aim of the present study was to evaluate the prevalence of peri-implant soft tissue dehiscence (PSTD) and the clinical and ultrasonographic risk indicators for this conditio...
Article
Objective To clinically evaluate the use of a titanium‐reinforced PTFE mesh for vertical bone augmentation (VBA) of deficient alveolar ridges. Materials and methods This case series documented consecutive patients treated for VBA with a newly developed PTFE mesh. VBA was performed in anterior and posterior, maxillary and mandibular arches using an...
Article
Implant-related esthetic demands have increased tremendously in recent years. The presence of shallow papillae or open interproximal spaces (black triangles) are some of the most troubling dilemmas in dentistry. Among the many factors associated with the presence of papilla or papilla height, the interproximal bone is one of the main factors dictat...
Article
Objectives To evaluate long‐term clinical and radiographic outcomes of dental implants placed after lateral window sinus augmentation utilizing the sagittal sandwich technique. Materials and Methods Patients treated with sinus augmentation were included in this retrospective case series study. The surgical procedure was performed with particulate...
Article
Full-text available
The significance of keratinized mucosa around dental implants for the prevention of biologic complications has been a subject of controversy. Agreement, however, exists on the benefits provided to achieve more satisfactory oral hygiene measures and reduced clinical inflammation. A prospective interventional case series of 14 patients (31 implants)...
Article
Full-text available
Several techniques involving the harvesting of a soft tissue graft from the palate have been proposed for regenerating keratinized mucosa (KM) at implant sites. However, patient morbidity and poor esthetic outcomes are considered the main drawbacks of these approaches. Therefore, the aim of this study was to describe and evaluate a new technique fo...
Article
Background: The peri-implant soft tissue phenotype (PSP) encompasses the keratinized mucosa width (KMW), mucosal thickness (MT) and supracrestal tissue height (STH). Numerous PSP approaches to augment soft tissue volume around endosseous dental implants have been investigated. To what extent PSP modification is beneficial for peri-implant health h...
Article
Full-text available
Purpose: There is a lack of knowledge concerning the critical buccal bone thickness required for securing favorable functional and esthetic outcomes, conditioned to the dimensional changes after implant placement. A preclinical study was therefore carried out to identify the critical buccal bone wall thickness for minimizing bone resorption during...
Article
Background: Cawood-Howell class IV atrophies, also known as "knife-edge" ridges, represent a serious horizontal defect, making the placement of regular implants challenging. Aim: To clinically and radiographically evaluate bone regeneration of severe horizontal bone defects with 3 years of follow-up. Materials and methods: This study was desig...
Article
Guided bone regeneration is an effective alternative for the reconstruction of atrophic ridges. Adequate flap management together with immobilization of the barrier membrane and graft are crucial to ensure successful regenerative radiographic and clinical outcomes. Moreover, tension-free flap closure should be accomplished to guarantee to maximize...
Article
Full-text available
Background and Aims Bone augmentation procedures to enable dental implant placement are frequently performed. The remit of this working group was to evaluate the current evidence on the efficacy of regenerative measures for the reconstruction of alveolar ridge defects. Material and Methods The discussions were based on four systematic reviews focu...
Article
Guided bone regeneration is an effective alternative for the reconstruction of atrophic ridges. Adequate flap management together with immobilization of the barrier membrane and graft are crucial to ensure successful regenerative radiographic and clinical outcomes. Moreover, tension-free flap closure should be accomplished to guarantee to maximize...
Article
Objectives To compare clinical performance of a novel resorbable non‐cross‐linked collagen membrane, creos xenoprotect (CXP), with a reference membrane (BG) for guided bone regeneration (GBR) at dehisced single implant sites. Materials and Methods This randomized controlled trial included patients with simultaneous implant placement and GBR at deh...
Article
AIM: The primary aim of this systematic review was to evaluate the effect of various techniques used for vertical ridge augmentation on clinical vertical bone gain. MATERIAL AND METHODS: A protocol was developed to answer the following focused question: "In patients with vertical alveolar ridge deficiencies, how effective are different augmentation...
Article
Predictable and effective surgical techniques that aim to increase the width of keratinized gingiva, relocate the mucogingival junction, and deepen the vestibule often involve soft tissue autografts; however, soft tissue autograft supply is limited and its harvesting is associated with patient morbidity. With a strip autograft and xenogeneic collag...
Conference Paper
Background & Aim: Guided bone regeneration (GBR) at sites with dehiscence defects can facilitate simultaneous implant placement. The aim of this report was to evaluate bone formation and soft-tissue healing in defects treated using creos xenoprotect (CXP) or Bio-Gide (BG) resorbable collagen membranes 1-year after definitive prosthesis delivery. Me...
Article
Vertical ridge augmentation (VRA) procedures before or during dental implant placement are technically challenging and often encounter procedure-related complications. To minimize complications and promote success, a literature search was conducted to validate procedures used for VRA. A decision tree based on the amount of additional ridge height n...
Article
Full-text available
Vertical ridge augmentation in the posterior mandible is a technique-sensitive procedure that requires adequate anatomical knowledge and precise surgical skills to minimize the risk of complications. One of the most important but also challenging aspects of the surgical technique is proper flap management to allow for passive flap closure and reduc...
Data
Appendix S1. CONSORT 2010 checklist of information to include when reporting a randomised trial.
Article
Full-text available
Maxillary sinus floor elevation has been documented as a safe and predictable procedure for gaining vertical bone height in the atrophic posterior maxillae. Conversely, there is a lack of basic research on the characteristics of the union between the sinus membrane (SM) and the bone. Clinical implications of an impaired union in healthy or patholog...
Poster
Full-text available
Interim study results have shown that the new resorbable collagen membrane facilitates bone augmentation in dehiscence defects similarly to the reference membrane. At definitive prosthetic placement, patients reported high functional and esthetic satisfaction, as well as a higher quality-of-life compared to pre-treatment. These findings further sup...
Article
Full-text available
Regenerative therapies are commonly needed prior to implant placement in the posterior maxilla following tooth extraction. The aim of this study was to investigate the anatomical features of the atrophic posterior maxilla that might affect surgical approach selection and technique and risk of intra- and postoperative complications. Cone beam comput...
Article
Guided bone regeneration has become more predictable due to advances in material sciences. Nevertheless, vertical ridge augmentation (VRA) remains a potential challenge due to the complexity of soft tissue management. This becomes more complicated in the posterior atrophic mandible due to limited access and poorer blood supply. As such, a number of...
Article
Purpose: The etiology and progression of periimplant mucogingival defects are multifactorial. As such, the aim of this study was to discern and discuss the key long-term prognostic factors that change the balance of homeostasis/regeneration in periimplant mucogingival and recession defects. Materials and methods: This report provides cases and a...
Article
Mandibular ridge augmentation via guided bone regeneration in the atrophic mandible is considered one of the most challenging scenarios for implant-supported oral rehabilitation. Uneventful wound healing has clearly demonstrated its impact on the final regenerative outcome. Soft tissue management must be precise and adequate to attain flap-free wou...
Article
Full-text available
Reformation of the lost interdental papilla remains one of the most challenging goals for clinicians. When a single tooth is replaced with an implant, the papilla between the tooth and the implant can often be maintained or predictably reformed as long as the adjacent tooth's periodontal attachment and bone are preserved. However, if the periodonta...
Article
Full-text available
Objective: To compare clinical performance of a new resorbable non-cross-linked collagen membrane, creos xenoprotect (CXP), with a reference membrane (BG) for guided bone regeneration at dehisced implant sites. Materials and methods: This randomized controlled clinical trial enrolled patients with expected dehiscence defects following implant pl...
Article
Full-text available
Restoration of lost interdental papilla remains one of the most challenging goals for clinicians. When a single tooth is replaced with an implant, the papilla between the tooth and the implant can often be maintained or predictably reconstructed as long as the periodontal attachment and bone of the adjacent tooth is preserved. However, if the perio...
Article
Aim: To clinically and radiographically evaluate bone regeneration of severe horizontal bone defects. Materials and methods: This study was designed as a single cohort, prospective clinical trial. Partially or fully edentulous patients, having less then 4 mm of residual horizontal bone width were selected and consecutively treated with resorbabl...
Article
Full-text available
Background: To the best of the authors' knowledge, there is very limited clinical data on the outcomes of simultaneous guided bone regeneration (GBR) for horizontal and/or vertical bone gain for the reconstruction of severely atrophic edentulous maxilla. Therefore, the purpose of the clinical series presented herein was to clinically evaluate long...
Article
Full-text available
Severe vertical ridge deficiency in the anterior maxilla represents one of the most challenging scenarios in bone regeneration. Under ideal circumstances, guided bone regeneration in combination with soft tissue management has shown predictable esthetic and functional outcomes. Success largely relies on primary wound closure during and after the su...
Article
Full-text available
Osteosynthesis screws and titanium or resorbable pins have been recommended for fixing guided bone regeneration (GBR) membranes and stabilizing the graft. However, the removal of fixation screws or pins often requires an additional surgical procedure. This article presents a periosteal suturing technique with resorbable sutures for the fixation of...
Article
Full-text available
Severe vertical ridge deficiency in the anterior maxilla represents one of the most challenging clinical scenarios in the bone regeneration arena. As such, a combination of vertical bone augmentation using various biomaterials and soft tissue manipulation is needed to obtain successful outcomes. The present case series describes a novel approach to...
Chapter
Several treatment modalities have been developed for vertical bone growth, including distraction osteogenesis, onlay bone grafting, and vertical guided bone regeneration (GBR). This chapter reviews the different techniques available for vertical bone augmentation, describes techniques and patient selection criteria for vertical augmentation with GB...
Article
Full-text available
Large areas of mucogingival alterations may result from advanced regenerative procedures. This prospective case series study was performed to introduce and evaluate a surgical approach that combines the strip gingival graft technique with the use of a xenogeneic collagen matrix. The primary outcome measurement was the increase in keratinized tissue...
Article
Full-text available
The objective of this study was to assess implant therapy after a staged guided bone regeneration procedure in the anterior maxilla by lateralization of the nasopalatine nerve and vessel bundle. Neurosensory function following augmentative procedures and implant placement, assessed using a standardized questionnaire and clinical examination, were t...
Article
Background: The scope was to review the three main clinical indications in periodontal plastic surgical procedures. Aims: To review the fundamental principles in periodontal plastic surgery, the main surgical designs in flap surgery applied to the treatment of recessions, periimplant soft tissue deficiencies and soft tissue ridge augmentation, as w...
Article
Full-text available
Purpose: This prospective case series evaluated the use of a new titanium-reinforced nonresorbable membrane (high-density polytetrafluoroethylene), in combination with a mixture of anorganic bovine bone-derived mineral (ABBM) and autogenous particulated bone, for vertical augmentation of deficient alveolar ridges. Materials and methods: A mixtur...
Article
Full-text available
This clinical case report describes and demonstrates the successful use of purified recombinant human platelet-derived growth factor in conjunction with autogenous bone, an organic bovine bone-derived mineral, and a barrier membrane to reconstruct severe alveolar bone defects. Significant horizontal bone regeneration was achieved in the posterior m...
Article
Full-text available
This prospective case series evaluated the use of a resorbable natural collagen membrane with a mixture of autogenous bone and anorganic bovine bone-derived mineral (ABBM) for lateral ridge augmentation and subsequent implant placement. A mixture (1:1) of particulated autogenous bone and ABBM was used for lateral ridge augmentation and covered with...
Article
Full-text available
Seeding of bone implants with mesenchymal stem cells (MSCs) may promote osseointegration and bone regeneration. However, implant material surfaces, such as titanium or bovine bone mineral, fail to support rapid and efficient attachment of MSCs, especially under serum-free conditions that may be desirable when human applications or tightly controlle...
Article
Full-text available
The aims of this clinical study were to evaluate the occurrence of sinus graft infection and the results of a planned surgical and pharmacologic treatment regimen to eliminate infections and preserve the graft. Patients were consecutively treated with sinus floor elevations using the lateral window technique. If a clinical diagnosis of sinus graft...
Article
Healthy, well-structured mucosa may clinically disguise atrophic jawbone in preimplant diagnosis. To analyze bone width in relation to the complete ridge thickness comparing the anterior with the posterior edentulous maxilla. Data of 52 patients (mean age 62 ± 9 years) who were edentulous for at least 1 year and who received implant treatment were...
Conference Paper
Vertical and horizontal augmentation presents one of the greatest challenges of bone regeneration in implant dentistry. This is primarily due to the difficulty of the surgical procedure and its potential complications. Several treatment modalities have been developed for vertical and horizontal bone growth, including distraction osteogenesis, onlay...
Conference Paper
The peri-implant mucosa has been studied extensively. It consists a two millimeter long junctional epithelium and more apically a one and a half millimeter connective tissue layer. It has been demonstrated that the junctional epithelium is attached to the titanium surface with hemidesmosomes and the connective tissue layer is rich in collagen fiber...
Article
Full-text available
This prospective case series evaluated the use of a new synthetic resorbable membrane with autogenous bone, either alone or in combination with anorganic bovine bone-derived mineral, for horizontal ridge augmentation and subsequent implant placement. Particulated autogenous bone, either alone or in combination with anorganic bovine bone-derived min...
Article
Full-text available
The aims of this prospective study were to: (1) determine clinical and radiographic success and survival rates of implants placed in a staged procedure after sinus augmentation; and (2) compare the success and survival rate of implants in two patient groups with different ridge height prior to treatment (those with minimal residual crestal bone [⋜...
Article
Full-text available
This clinical case report describes and demonstrates successful use of recombinant human platelet-derived growth factor (rhPDGF-BB) in conjunction with autogenous bone, anorganic bone mineral, and barrier membranes to reconstruct severe alveolar bone defects. A combined sinus augmentation and vertical alveolar ridge augmentation was successfully pe...
Article
Full-text available
The aims of the current study were to: (1) evaluate the results of vertical guided bone regeneration (GBR) with particulate autogenous bone grafts, (2) determine clinically and radiographically the success and survival rates of 82 implants placed in such surgical sites after prosthetic loading for 12 to 72 months, and (3) compare defects that were...
Article
Full-text available
This clinical case report describes and demonstrates successful use of recombinant human plateletderived growth factor (rhPDGF-BB) in conjunction with autogenous bone, anorganic bone mineral, and barrier membranes to reconstruct severe alveolar bone defects. A combined sinus augmentation and vertical alveolar ridge augmentation was successfully per...

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Projects (2)
Project
This book expertly describes the key features of vertical and horizontal ridge augmentation.