Isabelle Claudet

Centre Hospitalier Universitaire de Toulouse | CHU Toulouse · Pediatric emergency

Importance Acute bronchiolitis is the leading cause of hospitalization among infants. Previous studies, underpowered to examine hospital admission, have found a limited benefit of nebulized hypertonic saline (HS) treatment in the pediatric emergency department (ED). Objective To examine whether HS nebulization treatment would decrease the hospital...

Background: Chronic cannabis users may experience cyclical episodes of nausea and vomiting and learned behavior of hot bathing. This clinical condition, known as cannabis hyperemesis syndrome, was first reported in 2004. Objective: Our aim was to promote early recognition of this syndrome in emergency departments (EDs) and to increase referral t...

Conclusion: This study supports the impression that accidental child poisonings with cannabis have been more serious than previously thought for 2 years. This observation may be explained by (1) the increased THC concentration in cannabis and (2) the widespread use in young adults, even after they become parents. Introducing an addiction team insi...

Background and objectives: In France, cannabis consumption is illegal. The health impact of its increasing use and higher tetrahydrocannabinol (THC) concentrations is still poorly documented, particularly that of unintentional pediatric intoxications. We sought to evaluate the French national trend of admissions for unintentional cannabis intoxica...

Background and objective: In the European Union, the record of cocaine-related seizures indicates an expanding supply. The purity has also been increasing. The health impact of these trends remains poorly documented, in particular, the changes and clinical manifestations of intoxication in young children. We attempted to evaluate the trend in Fren...

Background: Each year, new pediatric residents begin their shifts in the pediatric emergency room. While technical skills are often acquired during workshops, non-technical skills such as communication, professionalism, situational awareness, or decision-making are rarely tested. Simulation enables non-technical skills to be developed in situation...

We report a pediatric case of ecstasy intoxication via an unusual route. A mother called the emergency services after her daughter had inserted an ecstasy pill into her nose. During transportation, the child developed hypertension, tachycardia, and tachypnea. She was admitted to the nearest regional hospital, where a physical examination revealed p...

Résumé Selon le principe de précaution et face à l’incertitude initiale de la gravité potentielle de la Covid-19, la France a adopté des mesures collectives comprises comme acceptables malgré la privation de liberté et les risques connus d’un confinement long sur la santé mentale des individus. De telles mesures devraient être appliquées de façon p...

Introduction: Few studies have examined the psychopathological consequences for parents of children who were survivors of a motor vehicle crash (MVC). This study assessed the impact of dissociation and peritraumatic distress on the severity of PTSD and post-traumatic major depressive episode (MDE) symptoms in mothers during the first years after th...

Objectif : L’article souligne qu’une épidémie virale et les stratégies pour y faire face 1) ont un impact majeur sur des groupes a priori épargnés par la maladie elle-même, ici les enfants, et 2) peuvent générer des problèmes sanitaires au-delà de la maladie et conduire à d’importantes difficultés sociales, économiques, scolaires et à un accroissem...

Objective: This article underlines that a viral epidemic and strategies to deal with it 1) have a major impact on groups that are a priori spared by the disease itself, in this case children, and 2) can generate health problems beyond the disease and lead to major social, economic and educational difficulties and an increase of social inequalities...

The first containment of the Sars-Cov2 pandemic had the potential to generate posttraumatic stress (PTS) symptoms in children. Objective : The main objective of the study was to determine the prevalence of PTS symptoms within 6 weeks of the end of lockdown, in children contained between March 17, 2020 and May 11, 2020 in France. Material and Meth...

Résumé Contexte Conscient·e·s des difficultés engendrées par la pandémie de COVID-19 pour de nombreuses familles ayant des enfants de 6 ans ou moins, l’étude se focalise sur trois contextes de vulnérabilités familiales : familles monoparentales, avec enfants ayant des difficultés développementales et celles en situation de pauvreté. Méthode Un ques...

Background: After the COVID-19 pandemic reached France in January 2020, a national lockdown including school closures was officially imposed from March 17, 2020, to May 10, 2020. Pediatric intensive care units (PICUs) admit critically ill infants, children and teenagers with severe acute conditions, in particular infectious and traumatic diseases....

Background Today, one in eight migrants and one in two refugees are children. Since this population has been less studied than the adult population, there is little data available on the state of health of this pediatric migrant population and the reasons they seek care. Objective The objective of this study was to describe the sociodemographic an...

Introduction Bronchiolitis is the leading cause of hospitalization for infants but its economic burden is not well documented. Our objective was to describe the clinical evolution and to assess the 1-month cost of a first episode of acute bronchiolitis presenting to the emergency department (ED). Methods Our study was an epidemiologic analysis and...

Background Sudden unexpected infant death (SUID) remains the leading cause of postnatal mortality in many countries. French and international guidelines recommend a thorough examination with toxicology studies. Objectives The main objective was to determine the prevalence of toxic detection and positive analyses. The secondary objectives were to d...

on behalf of the OMIN Study Group (2021): Prevalence of positive toxicology analysis from the French national registry for sudden unexpected infant death (Tox-MIN), Clinical Toxicology, ABSTRACT Background: Sudden unexpected infant death (SUID) remains the leading cause of postnatal mortality in many countries. French and international guidelines r...

Not urinating regularly, voluntarily restraining oneself at school promotes the occurrence of voiding disorders. Aim: To determine the prevalence of such disorders in elementary schools (students from 1st to 5th grade) and analyze the role of access to school toilets on voiding habits. Method: Observational, descriptive epidemiological study du...

Introduction-Depuis la mise en place des mesures de confinement en lien avec la pandémie de Covid-19, les services d'urgences ont observé une diminution des recours aux urgences pour accident de la vie courante (AcVC) des cas peu graves et une augmentation des cas graves, notamment chez les jeunes enfants et les personnes âgées. L'objectif de cette...

Objectifs Les MIN sont la première cause de mortalité en France chez les enfants de moins de 1 an. En 2015, sous l’impulsion de l’association des centres référents de la MIN (Ancremin) et le CHU de Nantes l’Observatoire national des Morts Inattendues du Nourrisson (OMIN) a été créé. Il regroupe 35 des 37 centres de référence MIN (DROM inclus) franç...

Background Poisoning is one of the leading causes of admission to the emergency department and intensive care unit. A large number of epidemiological changes have occurred over the last years such as the exponential growth of new synthetic psychoactive substances. Major progress has also been made in analytical screening and assays, enabling the cl...

Nous sommes un groupe de chercheur.e.s en sciences humaines et sociales (psychologie, sociologie, sciences de l’information et de la communication, anthropologie) et en santé publique et médecine, étudiant le développement des jeunes enfants au sein de leurs familles et dans différents contextes de vie. La pandémie actuelle liée à la COVID-19 peut...

Thrombocytopenia (defined by platelet count <150 x 10⁹/L) has been observed in up to 36% of patients with the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus responsible for Coronavirus disease 2019 (COVID‐19; Guan et al , 2020). In this setting, thrombocytopenia is usually mild, caused by platelet activation and consumption...

Background and Objectives The incorporation of drugs in the hair of young children differs from that of adults and the metabolism of cannabis cannot be the same. Our primary objective was to analyze the distribution of the different cannabinoids in children’s hair samples. The secondary objective was to correlate the intensity of toxic environmenta...

Pediatric ocular trauma is a major cause of acquired monocular blindness. Post-traumatic visual impairment can lead to significant handicap. In France, recent data on the epidemiology of pediatric ocular trauma are lacking. Aim To describe the characteristics of a pediatric cohort with ocular trauma and to analyse patient outcomes. Material and m...

Background Short treatments for acute bone and joint infections (BJI) are recommended. We implemented a protocol in 2009 to improve diagnosis and bacteriological documentation, and to shorten antibiotic therapies as per French guidelines (French Pediatric Infectious Disease Group, GPIP). Methods To assess the impact of the new clinical protocol fo...

Introduction L’intoxiqué pédiatrique se distingue de l’intoxiqué adulte surtout avant l’âge de 6 ans. Ce groupe d’âge est caractérisé par des expositions souvent accidentelles, mono-médicamenteuses, connues, et en proportion un taux d’intoxication attendue faible mais qui augmente avec l’âge (8 % versus 18 % après 12 ans) [1]. Critères d’hospitali...

Background: We report a case of geometrical skin lesions in a teenage patient. Case: A previously healthy 14-year-old boy presented in our pediatric emergency department with unusual skin lesions on his left forearm. The patient said the lesions started 2 weeks earlier following a spider bite. His physical examination revealed an otherwise healt...

Cardiac arrhythmia with sudden death is rare in children but mainly due to ventricular tachycardia. In case of pulseless ventricular tachycardia, prehospital treatment is crucial with immediate cardiopulmonary resuscitation and external electrical cardioversion. We report the case of pulseless ventricular tachycardia in a child with no past medical...

La fiebre es una reacción inespecífica de defensa del organismo como respuesta a la acción de diferentes agentes desencadenantes denominados pirógenos exógenos. La fiebre es una señal de alarma. La hipertermia es una elevación de la temperatura central por encima de los 38 °C. Para medir la temperatura en el lactante menor de 2 años, la vía rectal...

Two healthy children, a 10-year-old boy and a 13-year-old girl, both with no previous medical history, unrelated, presented with pinpoint purpura of the chin and the upper lip. It had appeared 2 days before and extended from the chin to the lower lip. Neither had fever or recent trauma, nor had they taken any medication. Their vital parameters and...

Introduction: Unintentional pediatric female genital trauma is frequent in the daily practice of emergency wards. However, scientific data are rare in the literature, leading to variability in their management. The aim of this study was to evaluate our practice in order to obtain epidemiological data and define clinical guidelines. Material and m...

Purpose: The main objective was to analyze the causes of such hallucinations in children presenting to a pediatric emergency department. Material and methods: We conducted a single-center, observational, retrospective study including all children aged less than 15 years experiencing hallucinations and admitted to our tertiary level pediatric eme...

La evolución de la reglamentación y la normalización de los productos han generado grandes adelantos respecto a la información que recibe la población y las categorías profesionales que participan en los accidentes de niños y adolescentes. La mortalidad ha disminuido en el 70% en 20 años. Sin embargo, esta reducción es más clara en lo que atañe a l...

Les expositions domestiques accidentelles à des toxiques sont très fréquentes chez le jeune enfant avant l’âge de 6 ans avec un pic autour de l’âge de 2–3 ans. Les intoxications sont faibles en proportion mais vont augmenter avec l’âge et la nature de certaines molécules ou produits. La représentation des différents toxiques impliqués (médicaments,...

Avec la mise sur le marché et la généralisation de la prescription de molécules d’utilisation récente (ex. tramadol, tryptans…) ou la commercialisation de nouveaux produits ménagers ou de consommation (capsules de lessive, liquide de recharge de e-cigarette…) de nouvelles intoxications sont apparues chez le jeune enfant avant l’âge de 6 ans.

Introduction Les intoxications accidentelles aux champignons représentent plusieurs centaines de cas chaque année en France. Ils font l’objet d’une surveillance par les centres antipoison et de toxicovigilance. L’objectif de ce travail était de décrire les intoxications ayant motivé un recours aux urgences. Méthodes L’enquête permanente sur les ac...

Résumé Les traumatismes trachéaux sont rares et souvent graves, notamment chez l’enfant. Si la prise en charge est standardisée chez l’adulte, permettant une décision rapide, la place des différents examens est moins claire en pédiatrie. Nous décrivons le cas d’une enfant âgée de 6 ans dont le recours au scanner nous a permis de décider de la condu...

Brucellosis is an overlooked infection of widespread geographic distribution. This disease is rarely evoked when assessing unexplained pediatric fever, and only 20-30 cases (children and adults) are confirmed per year. Risk factors for contracting brucellosis are exposure to bodily fluids and consumption of unpasteurized dairy products from infecte...

Grâce à l'évolution de la réglementation et la normalisation des produits, d'importants progrès ont été accomplis pour informer la population et les catégories professionnelles intervenant auprès des enfants sur les accidents survenant chez les enfants et adolescents par des campagnes nationales, régionales ou départementales. La mortalité a ainsi...

To warn physicians and parents about the risk of macaque bites, we present two pediatric cases (a 4-year-old boy and a 10-year-old girl) of bites sustained while on holiday. The young boy developed febrile dermohypodermitis and was hospitalized for IV antibiotic treatment. He received an initial antirabies vaccine while still in the holiday destina...

Objectives To compare the number of cerebral CT scan respectively recommended for pediatric minor head trauma by the application of the Pediatric Emergency Unit protocol and the recent SFMU guidelines. Patients and methods Between 2007 and 2011, all children aged 9 months or younger admitted after a domestic accidental minor head trauma to a tertia...

Unlabelled: We report a case of a pseudo encephalitis presentation of pediatric intoxication - Case report - a 7 year-old girl was admitted to our pediatric emergency unit after she developed sudden agitation, visual and tactile hallucinations. She was febrile (38.3 °C). She had not experienced any recent head trauma, infection or toxic ingestion;...

Las exposiciones domésticas accidentales a tóxicos son muy frecuentes en los niños pequeños menores de 6 años, con un pico alrededor de los 2-3 años. Las intoxicaciones suponen un porcentaje pequeño, pero aumentan con la edad y según las características de algunas moléculas o productos. La distribución de los distintos tóxicos implicados (fármacos,...

Context: Hyperglycemia has been described in severe scorpion envenomation, we wanted to analyze if it was applicable to viper bites in children. Aim: To describe clinical, biological, and therapeutic characteristics of 83 children bitten by European viper (Vipera spp.) and to confirm that hyperglycemia is a risk factor for high-grade envenomatio...

Parents frequently bring their children to general or pediatric emergency departments (EDs), even though many of these visits are judged by others to be “nonurgent” and inappropriate. This study examined the motives behind parents’ decisions to take their children to a pediatric emergency department (PED). At a PED in Toulouse, France, 497 parents...

Objective: This study was conducted to determine the prevalence among 2nd and 3rd graders. Methods: Twenty-five schools in a region in Southeastern France were sampled on the following criteria: school size, rural/urban location, underprivileged neighborhood or not, and private/public school. Second and third grade classes were randomly sampled...

Background Although the reliable and valid Child Post-Traumatic Stress Reaction Index (CPTS-RI) is a widely used measure of posttraumatic stress disorder (PTSD) symptoms in children, it has not been validated in French-speaking populations. The present study aims to assess the psychometric properties of the CPTS-RI in three samples of French-speaki...

Minoxidil hair formulation is commonly used for the treatment of male or female androgenic alopecia. This over-the-counter product is wrongly considered safe. The ingestion of a few milliliters by a child can lead to significant intoxication. We report a case of significant intoxication after the ingestion of topical minoxidil (Alopexy; Pierre Fabr...

Cannabis intoxication in toddlers is rare and mostly accidental. Our objectives were to focus on the characteristics and management of children under the age of 6 years who were admitted to our emergency department with cannabis poisoning reported as accidental by parents, and to point out the need to consider accidental cannabis ingestions as an i...

Background The use of a multiplex molecular technique to identify the etiological pathogen of respiratory viral infections might be a support as clinical signs are not characteristic. Objectives The aim of the study was to evaluate a multiplex molecular real-time assay for the routine diagnosis of respiratory viruses, to analyze the symptoms assoc...

New concentrated laundry pods, available on the European market for approximately 10 years, are associated with more severe intoxications compared to classic laundry detergents. Aim To compare symptoms and severity after exposure to classic laundry detergents and new laundry pods in a pediatric population. Material and methods Retrospective study...

New concentrated laundry pods, available on the European market for approximately 10 years, are associated with more severe intoxications compared to classic laundry detergents. To compare symptoms and severity after exposure to classic laundry detergents and new laundry pods in a pediatric population. Retrospective study conducted between 1st Janu...

Introduction Intussusceptions in infants and children are a medical and surgical emergency. A seasonal pattern, with fall and winter predominance, is usually taught in medical schools, but in France the epidemiological characteristics of intussusceptions are not clearly described. Methods We conducted a retrospective study concerning children with...