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Introduction
Skills and Expertise
Publications
Publications (24)
Background
Studies on Mass drug administration (MDA) in Ghana targeting various diseases, have mostly focused on factors that affect coverage and compliance to MDA with limited focus on evidence regarding awareness and community perception of the program. Therefore, this study sought to provide empirical evidence on the knowledge of onchocerciasis,...
Background and Aims
Sickle cell disease (SCD) is the commonest monogenic haemolytic disorder in Africa. Despite strides made in its management, a significant proportion of patients are hospitalized from the various complications of the disease. This study set out to describe the main causes and outcomes of hospitalizations among pediatric patients...
Background and Aims
Penicillin V prophylaxis protects children living with sickle cell disease (SCD) from bacteria infections especially Streptococcus pneumonia. However, the uptake of penicillin V prophylaxis is difficult to assess and often poor among SCD patients. Therefore, this study sought to investigate oral penicillin V prophylaxis adherenc...
Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy, characterized by painful episodes, anemia, high risk of infection, and other acute and chronic complications. In Africa, where the disease is most prevalent, large longitudinal data on patients and their outcomes are lacking. This article describes the experiences...
Background
Sickle cell disease (SCD) is the commonest monogenic haemolytic disorder in Africa. It continues to be a major public health burden. Newborn screening of SCD has been implemented in Kumasi, Ghana, since 1995 and SCD patients identified have been enrolled into the paediatric SCD clinic. The Sickle Pan African Research Consortium (SPARCo)...
(N Engl J Med. 2021;384:2028–2038. doi: 10.1056/NEJMoa2026486. PMID: 34038632; PMCID: PMC810848) While preterm, low–birth-weight infants make up ~15% of neonates, they account for the vast majority of neonatal deaths (70%). “Kangaroo Mother Care,” where the mother or caregiver provides continuous skin-to-skin contact with the neonate, has been show...
Introduction
Achieving high Mass Drug Administration (MDA) coverage and drug uptake are pivotal in the efforts to eradicate onchocerciasis. The present study investigated the extent and predictors of ivermectin MDA coverage and uptake from the individual and healthcare providers' perspectives. The extent of ivermectin distribution and uptake, and t...
Background
Poor community awareness and social mobilization serve as a major barrier by increasing absenteeism and downplaying the relevance of the ivermectin mass distribution by community members. Inadequate awareness also creates confusion among community members especially when one intervention is mistaken for the other. Methods
We designed a t...
Mass Drug Administration (MDA) of Ivermectin has proven to be safe and potent microfilaricide against Onchocerca volvulus. In Africa, coverage and compliance rates mostly fall below the World Health Organisation (WHO) target of 80% and 65% respectively. The study examined Ivermectin coverage, compliance and its enabling factors from the community i...
Sickle cell disease (SCD) is one of the most common blood disorders impacting planetary health. Over 300,000 newborns are diagnosed with SCD each year globally, with an increasing trend. The sickle cell disease ontology (SCDO) is the most comprehensive multidisciplinary SCD knowledge portal. The SCDO was collaboratively developed by the SCDO workin...
Purpose: Acute Respiratory Infection (ARI) is one of the topmost childhood killers ahead of diarrhoea and malnutrition in children. This exploratory qualitative study sought to examine the influence of maternal social constructs on the recognition and care seeking for fast breathing in children to inform the development of an intervention aimed at...
Background: Non-communicable diseases (NCDs) remain a global burden and is projected to increase due to aging, rapid urbanization and unhealthy lifestyles. The study was conducted to determine the prevalence of hypertension and diabetes in rural districts in the Ashanti region of Ghana and to determine factors that influence utilization of health c...
BACKGROUND. Pneumonia remains the foremost cause of death in young children in sub-Saharan Africa. This phenomenon is largely driven by poor access to healthcare and delay in seeking medical care for childhood pneumonia. OBJECTIVE. To assess the effectiveness of training caregivers to recognise the early clinical signs of pneumonia. METHODS. The st...
Infants and children under five years generally have high susceptibility to pathogenic and opportunistic infections due to immaturity and inexperience of their immune responses. The lives of these young children are threatened when they consume pharmaceutical preparations of poor microbiological quality. Considering the widespread use of artemether...
Purpose
Antibiotics are progressively failing in the fight against infections due to S. aureus because the bacterium has an outstanding ability to acquire multi-antibiotic resistance and become resistant to most antibiotics. Multi-drug resistant S. aureus poses a major threat to the foundation upon which standard antibacterial chemotherapy stands,...
Objectives: This study was conducted to determine the source of medicines and medicine information of persons living with hypertension and diabetes in rural and urban Ghana and assessing if they are influenced by predisposing and enabling factors as defined by Andersen’s behavioural model.
Methods: A population based cross sectional study was cond...
Background: The Expanded Programme on Immunization (EPI), since its inception in 1974, has helped avert about 2-3 million deaths annually. In Ghana, there is inadequate information on the transition from knowledge acquired in the classroom to practice among vaccinators. This study seeks to provide evidence on the level of knowledge and competencies...
Objective
This study sought to describe the trend of sputum organism density and the rate of bacteriological conversion among smear positive TB patients assessing care at the Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.
Methods
We conducted a retrospective patient folder review from January 2013 to March 2016 at the KATH, a tertiary hospi...
Background. Childhood poisoning is an important cause of morbidity in both developed and developing countries. Epidemiological studies on accidental poisoning in children show a consistent pattern regarding age and gender. Childhood poisoning is predominant in children <6 years of age and has a male preponderance, as boys are more active with a dri...
Background:Vaccines save more than 3 million lives and prevent 750,000 disabilities each year. Optimum immunization coverage will help in the fight against infectious diseases. This study was carried out to characterize current knowledge, attitudes, and practices
regarding immunizations in a rural Ghanaian community and to help identify reasons fo...
Cardiovascular diseases (CVDs), of which hypertension is a major risk factor, are predicted to account for four times as many deaths as from communicable diseases by the year 2020. Hypertension, once rare, is rapidly becoming a major public health burden in sub-Saharan Africa (SSA). However, data on its prevalence, awareness, treatment and control...
Background: Hypertension is the commonest modifiable risk factor of cardiovascular diseases and a major preventable cause of premature mortality. The worldwide prevalence of hypertension will increase by more than half by 2025; almost three-quarters of people with hypertension will be living in developing countries by 2025. We set out to evaluate t...