Isaac O Kowino

• Masinde Muliro University of Science and Technology

The search for novel therapies for tuberculosis continues due to the emergence of resistant strains, adverse drug reactions, and potential drug-drug interactions of antitubercular drugs. This study was undertaken to identify compounds from Entada abyssinica, a plant used by herbalists in East Africa for the management of symptoms of tuberculosis. A...

In this study, zinc oxide-activated carbon nanocomposite was used as the adsorbent for the remediation of dieldrin in aqueous media. Zinc oxide nanoparticles (ZNPs) were synthesized from Cissus quadrangularis (C. quadrangularis) leaf extract, and activated carbon was derived from maize cobs. Nanocomposites were formulated by mixing the ZNPs with th...

Aims: To determine the phytochemical composition and antibacterial activity of Solanum incanum fruits against Ralstonia solanacearum. Study Design: Experimental design involving completely randomized design Place and Duration of Study: The study was conducted at Original Research Article Karanja et al.; AJACR, 9(4): 1-16, 2021; Article no.AJACR.753...

Euclea divinorum Hern (Ebenaceae) has a long history of folkloric use in the treatment of different diseases. However, there are few reports on the responsible phytochemicals in its tender stems, leaves and root bark. The aim of this study was to compare the phytochemicals in E. divinorum leaves, tender stems and root bark. The plant materials were...

Background: Whereas the efficacy of Entada abyssinica (fabaceae) extracts against various ailments has been scientifically validated, its safety has not been established. This study was undertaken to evaluate the toxicity effects of methanolic stem bark extract of E. abyssinica on biochemical, haematological and histological parameters of Wistar al...

Phytochemicals in Rosmarinus officinalis leaves, their total phenolic content, antioxidant potential and antiproliferative activity against human prostate (DU145), colon (CT26) and cervical (HeLa 229) cancer cells were investigated. Extraction was done separately using hexane, dichloromethane, ethyl acetate and methanol. A total of 32 compounds wer...

Aim: To determine the phytochemicals in Ocimum gratissimum leaves, their phenolic content, antioxidant potential and antiproliferative activity against human prostate (DU145), colon (CT26) and cervical (HeLa 229) cancer cells. Place and Duration of the Study: Leaves of O. gratissimum were collected from cultivated plants in Wakiso district of Ugand...

Aim: Euclea divinorum Hern (Ebenaceae) is a treasured East African medicinal plant which has a long use in the management of dental caries. However, there are few reports on the antimicrobial activity of its different parts used in oral care. The aim of this study was to compare the antimicrobial activity of organic extracts of E. divinorum leaves,...

After repeated applications and long use of persistent pesticides in soils, a phenomenon known as enhanced (accelerated) degradation of some pesticides has been observed in soils. This has led to isolation of key microbes known to degrade these persistent pesticides in soils. The isolated microbes which are characterized and identified have been us...

Carbofuran (2,3-dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate) has been used within the Nzoia River Basin (NRB), especially in Bunyala Rice Irrigation Schemes, in Kenya for the control of pests. In this study, the capacity of native bacteria to degrade carbofuran in soils from NRB was investigated. A gram positive, rod-shaped bacteria capable...