Isaac K. A. GalyuonUniversity of Cape Coast | UCC · Department of Molecular Biology and Biotechnology
Isaac K. A. Galyuon
PhD
About
57
Publications
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Introduction
Isaac K. A. Galyuon currently works at the Department of Molecular Biology and Biotechnology, University of Cape Coast. Isaac does research in Physiology, Molecular Biology and Biotechnology, Microbiology and drug discovery. Their current project is Identification of Striga-resistant cowpea lines for various agro-ecological zones of Ghana.
Four cowpea varieties have been released for the Northern Agro-ecological zones and three for the Southern Agro-ecological zone.
Additional affiliations
Education
September 2001 - September 2005
Publications
Publications (57)
This poster explains the functioning of the stay-green trait in sorghum
The poster explains the maintenance of yield in stay-green sorghums.
This poster demonstrated that introgressed stay-green QTL functions in a senescent background.
Aims: To access the responses of 22 soybean genotypes under drought stress during the flowering stage of development. Study Design: A completely randomized experimental design (CRD) was adopted in this study. Five seeds of each of the 22 soybean genotypes were planted in 12-liter (L) plastic buckets (with holes at the bottom) containing sandy loam...
The digital age is characterised with technologies that have even changed
the scope of education. A popular outcome of such technologies has been
the evolvement of e-learning. E-learning has become a solution to most
institutions in churning out education to the majority who cannot access
traditional education, especially in higher education. E...
Distance education has seen tremendous transformation over the years
due to technological innovations, especially web 2.0. The affordances of
this technology for delivering modern distance education have bridged the
distance phenomenon. Even in traditional distance education where face-to�face is dominant for specific periods within a time frame...
Aims: The study aimed at the quantification, isolation and characterization of hydrocarbon degrading bacteria in oil-contaminated and pristine soils. Methodology: Soil samples from petroleum hydrocarbon polluted sites at auto-mechanic workshops, a mechanic village, as well as pristine (control) soils, comprising of 14 sampling locations within Cape...
Antimicrobial peptides (AMPs) represent alternative strategies to combat the global health problem of antibiotic resistance. However, naturally occurring AMPs are generally not sufficiently active for use as antibiotics. Optimized synthetic versions incorporating additional design principles are needed. Here, we engineered amino-terminal Cu(II) and...
Soil properties of petroleum hydrocarbon contaminated soils from automobile mechanical shops in the Cape Coast Municipality of the Central Region of Ghana were investigated to assess their alternation due to the petroleum hydrocarbon contamination. Soil samples were collected from eight automobile mechanical shops and control sites and analyzed usi...
Fermentation of Theobroma cacao L. beans is the most critical stage in the production of cocoa products such as chocolates and its derivatives. There is a limited understanding of the complex response of microbial diversity during cocoa bean fermentation. The aim of the present study was to investigate microbial communities in the cocoa bean fermen...
Background and Objective: Throughout the world, antibiotic resistance has been recognized as an emerging major issue of concern. In this study, genes responsible for the production of extended spectrum beta-lactamase (ESBL) in various E. coli isolates were characterized. Materials and Methods: Isolates of E. coli were obtained from clinical and env...
Background and Objective: Throughout the world, antibiotic resistance has been recognized as an emerging major issue of concern. In this study, genes responsible for the production of extended spectrum beta-lactamase (ESBL) in various E. coli isolates were characterized. Materials and Methods: Isolates of E. coli were obtained from clinical and env...
The sections in this article are
Quantitative Traits – What They are and How They are Mapped
Biomarkers of the Senescence Process
Correlated Developmental Events as Second‐Order Senescence Traits
G × E and the Contribution of Biotic and Abiotic Factors
Case Studies
Exploitation of QTL Mapping for Senescence Traits
QTL , Senescence, Ageing an...
Cacao swollen shoot virus is a member of the family Caulimoviridae, genus Badnavirus and is naturally transmitted to Theobroma cacao (L.) by several mealybug species. CSSV populations in West African countries are highly variable and genetically structured into several different groups based on the diversity in the first part of ORF3 which encodes...
Cowpea [Vigna unguiculata L. (Walp)] is grown mainly for its protein-rich grains and is consumed in various forms in sub-Saharan Africa. Average grain yield in farmers’ fields is generally low due to a number of biotic and abiotic stresses. One hundred and six cowpea accessions from Ghana, which had previously been evaluated for seedling drought to...
Background: Escherichia coli is one of the most common causative agent of bacterial diseases. The prevalence of E. coli infection and its outbreak has been reported in many countries but scanty information is available on the antibiogram of this bacterium in Cape Coast, a major tourist destination in West Africa. Materials and Methods: The antibiot...
The accidental discovery of cisplatin some 50 years ago generated renewed interest in metallopharmaceuticals. Beyond cisplatin, many useful metallodrugs have been synthesized for the diagnosis and treatment of various diseases, but toxicity concerns, and the propensity to induce chemoresistance and secondary cancers make it imperative to search for...
The genetic variability of 28 sorghum genotypes of known senescence phenotype was investigated using 66 SSR markers well-distributed across the sorghum genome. The genotypes of a number of lines from breeding programmes for stay-green were also determined. This included lines selected phenotypically for stay-green and also RSG 03123, a marker-assis...
Cacao (Theobroma cacao L.) was introduced into West Africa from South America during the nineteenth century. However, cacao swollen shoot disease (CSSD) was first observed in Ghana in 1936 and, later, discovered in Nigeria, Côte d’Ivoire, Togo, and Sierra Leone. The objectives of this work were to assess the genetic diversity and spatial distributi...
Genetically engineered (GE) crops have a role to play in increasing agricultural productivity. However, efforts to promote genetic engineering agriculture in Africa have been met with some amount of resistance. Here, we report recent efforts to promote GE agriculture in Ghana, a West African nation considered one of Africa's model democracies and g...
Antimicrobial peptides (AMPs) have emerged as one of several viable options for treatment of infections caused by multidrug-resistant microorganisms, which continue to pose the single greatest public health challenge to humankind. Unlike conventional antibiotics, AMPs affects several key extracellular and intracellular targets in bacteria simultane...
Tissue culture enhances rapid multiplication of suckers to supplement conventional methods to produce pineapples to meet both local and international demands. However, culture initiation, the most critical step towards rapid multiplication in vitro, is challenged by microbial contamination, exogenous growth hormone requirements and type of explants...
Cassava mosaic disease (CMD), caused by cassava mosaic geminivirus (CMG) is the most-important disease threatening production of cassava (Manihot esculenta) in Ghana. The disease is best managed through host-plant resistance. The study was conducted to assess resistance of 38 cassava genotypes to CMD, determine the associated resistance gene, and t...
Despite its existence in Ghana, there is very little information on the extent or nature of bovine tuberculosis. This state of affairs may pose a serious public health threat through risks associated with the consumption of beef from infected cattle, dairy milk and other bovine products. A study to screen bovine carcasses with lesions suggestive of...
The development of crops adapted to the semi-arid and arid regions would enhance food security in Africa. As part of research towards ensuring food security, field trials were carried out to evaluate the performance of sixteen hybrids of drought tolerant Quantitative trait loci (QTL) introgression lines of pearl millet in a Guinea-Savannah zone of...
Peptic ulcer is among the most serious gastrointestinal diseases in the world. Several orthodox drugs are employed for the treatment of the disease. Although these drugs are effective, they produce many adverse effects thus limiting their use. In recent years, there has been a growing interest in alternative therapies, especially those from plants...
Peptic ulcer is among the most serious gastrointestinal diseases in the world. Several orthodox drugs are employed for the treatment of the disease. Although these drugs are effective, they produce many adverse effects thus limiting their use. In recent years, there has been a growing interest in alternative therapies, especially those from plants...
Cowpea [Vigna unguiculata (L.) Walp.] production in West Africa is constraint by Striga
gesnerioides parasitism associated with 83-100% yield loses which warrants development of
resistance varieties against the parasite. An exotic resistant genotype, IT97K-499-35 developed by
International Institute of Tropical Agriculture (IITA) was crossed with S...
Medicinal plants are used by traditional practitioners to treat several ailments. Ethnomedicinal studies on Trema orientalis Linn. Blume (Ulmaceae) have shown that it is used in the treatment of diabetes mellitus, respiratory diseases, oliguria, and malaria. This article is aimed at providing comprehensive information on the medicinal uses, biology...
Striga gesnerioides, commonly called witchweed, is a major constraint to growth and productivity of cowpea (Vigna unguiculata L. Walp) throughout West Africa. We have screened the cowpea accessions available in the germplasm collections from Ghana for their reaction to Striga gesnerioides, with the aim of identifying new sources of resistance to th...
Peptic ulcer is among the most serious gastrointestinal diseases in the world. Several orthodox drugs are employed for the treatment of the disease. Although these drugs are effective, they produce many adverse effects thus limiting their use. In recent years, there has been a growing interest in alternative therapies, especially those from plants...
The microbial load of the “old” and “new” Ghanaian Cedi notes and coins obtained from vari- ous sources in Cape Coast, Ghana was studied using the dilution plate technique between Sep- tember 2005 - March 2006 and September 2008 - March 2009. Isolations were made on Mac- Conkey agar for coliforms and other enteric bacteria, Plate Count agar for tot...
Cassava (Manihot esculenta Crantz) is an important food crop in many tropical countries in Africa, South America and Asia. However, yields are below the productivity of the crop. This requires breeding and selection for improved varieties. The current study therefore investigated genetic diversity among some Ghanaian preferred accessions which coul...
Glucose-6-phosphate dehydrogenase (G-6-PD) is a cytoplasmic enzyme involved in the metabolism of glucose. It has been reported that G-6-PD deficiency confers protection against falciparum malaria. Contrary to this, other researchers have reported that the presence of G-6-PD-deficiencieny does not necessarily prevent individuals from developing mala...
Genetic diversity and phylogenetic relationships among 141 cowpea (Vigna unguiculata L. Walp.) accessions collected throughout the nine geographical regions of Ghana were evaluated using simple sequence repeat (SSR) molecular markers. Twenty-five primer combinations pre-selected by their ability to polymerase chain reaction amplify SSRs from a set...
The scientific and economic significance of plant senescence means that much effort has been made to understand the processes involved and to devise means of manipulating them agriculturally. During the past few years there has been considerable progress in this regard, especially in the molecular, genetic and genomic aspects. Senescence has a trem...
Improved tolerance of cocoa to full sunlight has the potential of increasing yields while reducing the need for shade management. The effects of irradiance on growth and leaf adaptations in plants grown from seeds cr cuttings and subjected to full sunlight (1800 μmol m-2 s-1) or shaded conditions (900 μmol m-2s-1) were investigated. Leaf size, inte...
The effects of full sunlight and 50% sunlight on pigment content, gas exchange, and chlorophyll fluorescence were compared, with the aim of identifying physiological characteristics which can enhance tolerance to high irradiance in cocoa. Chlorophyll and carotenoid levels were reduced in full sunlight, but the mean chlorophyll-carotenoid ratio was...
This study was conducted in Domini and Amansuri Lagoons in the Western Region of Ghana in January, 2011 with the aim of assessing their physico-chemical and ecological health conditions using ecological indices e.g. richness and diversity of macroinvertebrate fauna along environmental gradients. Lagoon ecosystems have several physiographic attribut...
Glucose-6-phosphate dehydrogenase (G-6-PD), an enzyme expressed in most human tissues is important in the generation of reduced glutathione -a key product in the control of oxidative stress. A low activity of this enzyme in red blood cells leads to Glucose-6-phosphate dehydrogenase deficiency (G-6-PDD). This disease has been overlooked as one of th...
Supervisors : C.R. McDavid, F.B. Lopez, J.A. Spence. Thesis (M. Phil.)--The University of the West Indies, St. Augustine, Trinidad, 1994. Bibliography : leaves 125-136.