Isaac Fradkin

Isaac Fradkin
Hebrew University of Jerusalem | HUJI · Department of Psychology

Phd

About

28
Publications
5,177
Reads
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233
Citations

Publications

Publications (28)
Article
Full-text available
To attain goals, people must proactively prevent interferences and react to interferences once they occur. Whereas most research focuses on how people deal with external interferences, here we investigate the use of proactive and reactive control in dealing with unwanted thoughts. To examine this question, we asked people to generate an association...
Article
The finding that human decision-making is systematically biased continues to have an immense impact on both research and policymaking. Prevailing views ascribe biases to limited computational resources, which require humans to resort to less costly resource-rational heuristics. Here, we propose that many biases in fact arise due to a computationall...
Article
An open trial of a therapist-guided internet cognitive-behavioral therapy (ICBT) for panic disorder with and without agoraphobia (PD/A) was conducted. Ninety adults diagnosed with PD/A were treated using ICBT adapted from a face to face (FTF) protocol. Results were benchmarked against two FTF samples, one at the same research site using the same pr...
Article
Background and objectives This study examined whether ritualistic behaviors characteristic of obsessive-compulsive disorder (OCD) are a product of dysfunctional goal-directed behavior leading to habitual behavior (Gillan & Robbins, 2014). We used an explicit motor sequence learning task to investigate the repetition of chunked action sequences acro...
Article
The purpose of this study was to examine whether anxious and avoidant attachment styles improve during guided internet-based cognitive behavioral treatment (ICBT) for panic disorder, and if so, to identify potential theoretically driven mechanisms related to the change. We examined changes in anxious and avoidant attachment and their time-lagged (1...
Article
Experiencing doubt in an uncertain situation has been theorized to be an antecedent of compulsive checking. However, whether and when obsessive compulsive (OC) symptoms are associated with experiencing doubt and increased checking is unclear. In this study, we investigated the relationship between OC symptoms, the experience of doubt, and checking...
Article
Objective: This study examines relationships among different aspects of therapeutic alliance with treatment outcome, adherence and attrition in internet delivered cognitive behavioral therapy (ICBT) for panic disorder. Methods: We examined alliance-outcome relationships in ICBT (N = 74) using a newly developed self-report alliance measure that dis...
Article
The Pathological Narcissism Inventory (PNI) is a popular measure and the first to attempt to tap into both grandiose and vulnerable narcissism (GN/VN). However, data have raised questions as to whether it appropriately formulates GN and differentiates it from VN. In this study, we examined the Brief-PNI’s structure and construct validity, by using...
Chapter
Although exposure is considered one of the most effective treatments for the anxiety disorders, theories underlying the efficacy of the treatments vary. This chapter examines various forms of exposure in terms of emotional processing theory, the inhibitory learning model, and cognitive theory. The authors discuss how each relates to current literat...
Article
In this article, we develop a computational model of obsessive-compulsive disorder (OCD). We propose that OCD is characterized by a difficulty in relying on past events to predict the consequences of patients' own actions and the unfolding of possible events. Clinically, this corresponds both to patients' difficulty in trusting their own actions (a...
Article
Full-text available
Obsessive compulsive (OC) symptoms involve excessive information gathering (e.g., checking, reassurance-seeking), and uncertainty about possible, often catastrophic, future events. Here we propose that these phenomena are the result of excessive uncertainty regarding state transitions (transition uncertainty): a computational impairment in Bayesian...
Article
Compulsive checking is the most common ritual among individuals with obsessive-compulsive disorder (OCD). Yet, other than uncertainty, the variables prompting checking are not fully understood. Laboratory studies suggest that task conditions - whether threatening (anxiety-relevant) or neutral, and task type - whether requiring perceptual or reasoni...
Article
Obsessions are commonly described as intrusive, ego-dystonic, and ‘coming out-of-nowhere’. This might reflect an experience of low sense of agency (SoA), with SoA referring to the experience of being the source of our thoughts. The current study investigates the relationship between obsessive compulsive (OC) symptoms and the SoA over thoughts. Part...
Article
Full-text available
In the version of this Perspective originally published, at the end of the first paragraph of the section ‘Neural prediction as a potential mechanism for how experience sculpts the developing brain’ the citation to ref. 76 should have been to ref. 74, and at the end of the first sentence of the next paragraph ref. 76 should have been cited alongsid...
Article
It has long been assumed that social animals, such as humans, are born with a brain system that has evolved to support social affiliation. However, the evidence does not necessarily support this assumption. Alternatively, social animals can be defined as those who cannot survive alone and rely on members from their group to regulate their ongoing p...
Article
Full-text available
Information stored in visual short-term memory is used ubiquitously in daily life; however, it is forgotten rapidly within seconds. When more items are to be remembered, they are forgotten faster, potentially suggesting that stronger memories are forgotten less rapidly. Here we tested this prediction with three experiments that assessed the influen...
Data
A pilot experiment that quantifies the expected interaction between exposure duration and delay. This experiment was designed to generate an interaction between exposure duration and delay to be used as informed priors in the Bayesian inference. We used prior research that showed clear and robust modulation of forgetting rate and used it to make a...
Data
The Bayesian model. Bayesian linear regression. (PDF)
Data
Sensitivity analysis. We conducted sensitivity analysis to verify that the choice of non-informative priors did not significantly alter the posterior distributions. (PDF)
Data
Model fit comparison. Many studies in the field have modeled the distribution of errors and used a parameter of the distribution to quantify the precision in which items were recalled. Here we compared three models: the variable-precision (VP) model, a 2 part mixture model and a 3 part mixture model. (PDF)
Article
Obsessions are often described as aversive thoughts that come out-of-nowhere. Indeed, several models of obsessive compulsive symptoms postulate that obsessions are characterized by being unrelated to several levels of context (e.g. self-concept, external stimuli). In the current study we aim to broaden this notion by presenting a multidimensional c...
Article
Several recent models of obsessive compulsive disorder (OCD) consider it to be a neurocognitive disorder involving inflexibility and disinhibition. Indeed, previous reviews of neuropsychological functioning in OCD suggested impaired performance in flexibility tasks. The current meta-analysis examines whether the reported differences in flexibility...
Poster
The adaptive weighting of sensorimotor prediction errors in the ascription of agency over action
Article
Scrupulosity, or obsessive-compulsive symptoms related to religiosity or religion, is a common presentation of obsessive compulsive disorder (OCD), and it is important to elucidate its phenomenology and measurement. Today, the most widespread questionnaire for the assessment of scrupulosity is the Penn Inventory of Scrupulosity (PIOS). The current...
Conference Paper
Intrusive thoughts constitute a key feature of OCD. While the DSM-5 characterizes obsessions as intrusive and unwanted thoughts, and studies show that OCD patients report on a lower sense of control over thoughts, to our knowledge the question of authorship over thoughts in OCD was never tested experimentally. In this study we found that that high...
Presentation
Deficits in sensorimotor predictive coding in individuals with high obsessive-compulsive tendencies

Questions

Question (1)
Question
Hello.
I use Brainvision analyzer to analyze ERP data, and lately I've started to collect ECG in parallel to the EEG recording, in order to see the correlation between some ERP components and HR related measures (Specifically - the heart rate deceleration seems like a good candidate, as it is event related, but I'm also thinking about using HRV in an event-related style, if it's possible). I have some experience with using Analyzer for ERP analyses, and I was wondering whether anyone has any advise on how to use Analyzer to detect R-R intervals, and to analyze related measures.
Thanks a lot,
Isaac.

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