Irshad Mohiuddin

Thapar Institute of Engineering & Technology · School of Chemistry and Biochemistry

A novel and porous molecularly imprinted polymer (PMIP) was synthesized and used as a solid-phase extraction adsorbent for preconcentration of carbamazepine (CBZ) prior to its quantitation by high-performance liquid chromatography (HPLC) in various sample forms (e.g., drinking water, river water, hospital wastewater, and pharmaceuticals). PMIP-CBZ...

Diclofenac (DCF) is one of the most widely used anti-inflammatory drugs worldwide and is ubiquitously present in various environmental compartments. The occurrence and concentration of DCF in water bodies are emerging issues due to its detrimental effects and chronic toxicity in various organisms. In an effort to develop or improve quantitation tec...

This study has developed an efficient (94.9-99.4%) and fast (5 min) method for simultaneous identification and quantification of phenolic endocrine disrupting compounds with an emphasis on bisphenol A (BPA) and 4-cumylphenol (4-CP) in food stuffs using a dual-template magnetic, molecularly-imprinted polymer (dt-MMIP). The dt-MMIP was synthesized by...

In this research, the adsorptive performance of a starch-magnesium/aluminum layered double hydroxide (S-Mg/Al LDH) composite was investigated for different organic dyes in single-component systems by conducting a series of batch mode experiments. S-Mg/Al LDH composite showed preferential adsorption of anionic dyes than cationic dyes. The marked imp...

Chiral Ionic Liquids: Applications in Chemistry and Technology provide an in-depth exploration of the synthesis, design, and diverse applications of chiral ionic liquids (CILs) in modern chemistry. This comprehensive book covers fundamental concepts such as ionic liquids' structural organization and chirality, while also discussing advanced topics...

Herein, rice straw-based biochar was intercalated with Co/Al-LDH (LDH-Biochar) using a green technique based on the co-precipitation method. LDH-Biochar was further evaluated for the naked eye detection and spectrofluorimetric analysis of dibutyl phosphate (DBP), diphenyl phosphate (DPP), and diethyl chlorophosphate (DCP), which are extensively use...

The development of selective and practically applicable sensors for monitoring trace uranyl ions (UO22+) in an aqueous medium is the biggest challenge. This study presents the development of a conjugated oligoelectrolyte-based probe (COE) for the selective detection of UO22+ ions in water bodies. The COE is a water-soluble probe having an organic b...

A one-pot hydrothermal process incorporated nitrogen-doped fluorescent carbon dots (N-FCDs) into the pores of mesoporous silica (m-SiO2). Under weakly alkaline conditions, the m-SiO2/N-FCDs were further functionalized with dopamine to develop m-SiO2/N-FCDs modified polydopamine (m-SiO2/N-FCDs/PDA). The m-SiO2/N-FCDs/PDA exhibited emission at a wave...

Dual-functioning probes capable of detecting and removing hazardous substances have recently received increased attention compared to exclusive sensory probes. Herein, a new composite is synthesized by blending polydopamine imprinted polymers with fluorescent carbon dots (PIP-FCDs) for the selective recognition and adsorption of Ibuprofen (IBF), wh...

Physochlaina is a genus of flowering plants belonging to the family Solanaceae and consists of 10 species distributed in various Asian countries. The species of the genus have been traditionally used to cure a variety of illnesses due to their highly valuable medicinal properties, including cancer, asthma, cough, weakness, stomachache, diarrhea, sw...

The proper treatment of antibiotics has become a formidable challenge in environmental remediation. In this work, a mesoporous molecularly imprinted polymer (mMIP) was successfully fabricated on SiO2 by the sol gel process and used to selectively adsorb and detect antibiotic levofloxacin (LEVO). The adsorption characteristics of LEVO-mMIP were expl...

This study presents a new and rapid analytical high-performance liquid chromatography coupled with a photodiode array detector method for determining nickel ion (Ni2+) complex with Schiff base (Z)-1-(thiophen-2-yl-methyleneamino) propane-2-ol easily. The influence of pH, surfactant, and effect of mobile phase on the formation of the Ni-(Z)-1-(thiop...

A tripodal amine (TPA) with −OH, N, and S donors is synthesized to functionalize a core−shell carbon dot composite (FCDs@SiO2-TPA) for sensing application. The TPA is characterized by spectroscopic and spectrometric techniques, and the composite is characterized by Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), B...

In this study, a new Schiff base, (E)-2-(2-aminophenylthio)-N-(thiophen-2-yl-methylene) benzenamine was synthesized for selective detection of Hg²⁺. This Schiff base was characterized by proton nuclear magnetic resonance (¹HNMR), carbon-13 nuclear magnetic resonance (¹³CNMR), and Fourier-transform infrared (FTIR) spectroscopy. Binding interaction b...

A glucosyl appended chromone-based diorganotin(IV) crystalline solid (DOC) is obtained from β-D-allopyranoside substituted 3-hydroxy-benzo-γ-pyrone. The combination of organotin(IV) unit, glucosyl substituent and chromone skeleton introduced some special features to the solid including controlled solubility, water stability, and plenty of interacti...

An organic-inorganic composite was fabricated by the intercalation of chitosan Schiff base (Chitosan@SB) in the layers of Co/Al layered double hydroxide (Co/Al-LDH) to get the amalgamated properties of parent materials like fluorescent nature and porosity. The structural properties of Chitosan Schiff base intercalated layered double hydroxide (Chit...

Synthesis and Applications of Semiconductor Nanostructures consists of 15 chapters that focus on synthesis, characterization and multifaceted potential applications of semiconductor nanostructures, metal organic frameworks (MOFs) and nanostructure impregnated metal-organic frameworks (MOFs). Special materials included in the volume include doped gl...

Synthesis and Applications of Semiconductor Nanostructures consists of 15 chapters that focus on synthesis, characterization and multifaceted potential applications of semiconductor nanostructures, metal organic frameworks (MOFs) and nanostructure impregnated metal-organic frameworks (MOFs). Special materials included in the volume include doped gl...

As a commonly well-known industrial chemical, phthalates are produced in high volumes to be used in various consumer products (e.g., plasticizers, medical devices, construction materials, and toys) to enhance softness, durability, transparency, and flexibility. Phthalates are generally not chemically bonded to the polymer chain of the plastic in wh...

Molecularly imprinted fluorescent carbon dots (MI-FCDs) find numerous applications in analytical chemistry due to their outstanding photoluminescent properties and having specific pockets for the recognition of target molecules. Despite significant advances, practical applications of MI-FCDs-based fluorescent sensors are still in their initial stag...

Diclofenac (DCF) is a pharmaceutical contaminant of water bodies and therefore, improvement of analytical techniques for its removal and quantitation is one of the current interests of analysts. Herein, DCF selective magnetic molecularly imprinted polymer (MMIP) has been fabricated and characterized by Fourier transform-infrared spectroscopy, therm...

An amine-decorated zirconium based metal organic framework (MOF) UiO-66-NH2 with rod shape morphology was synthesized by solvothermal process using 2-aminoterephthalic acid as an organic linker. Crystallinity of synthesized MOF material was confirmed with PXRD technique. MOF was employed as selective and sensitive sensor for ultra-trace detection o...

In this work, a highly selective and sensitive protocol has been developed to detect aspirin (ASP) by using mesoporous silica nanoprobe equipped with molecular imprints and fluorescent carbon dots (ms-MIP-FCDs). The fabrication of nanoprobe is based on the reprocessing of rice straw to fluorescent carbon dots (FCDs) and their amalgamation with mole...

A useful tool is established for the selective identification and isolation for a list of phthalates (PTHs: e.g., dimethyl phthalate, dipropyl phthalate, dibutyl phthalate, benzyl butyl phthalate, and dioctyl phthalate) based on restricted access medium magnetic molecularly imprinted polymer (RAM-MMIP). The RAM-MMIP has been synthesized by a surfac...

An amine-decorated zirconium-based metal–organic framework (MOF, coded as UiO-66-NH 2 ) with rod shaped morphology has been solvothermally synthesized using low-cost and easily available 2-aminoterephthalic acid as an organic linker. The crystallinity of the synthesized MOF material has been confirmed by sharp PXRD diffraction pattern. Photolumines...

In this study, a new Schiff base, ( E )-2-(2-aminophenylthio)- N -(thiophen-2-yl-methylene) benzenamine was synthesized for selective detection of Hg ²⁺ . This Schiff base was characterized by proton nuclear magnetic resonance ( ¹ HNMR) spectroscopy, carbon-13 nuclear magnetic resonance ( ¹³ CNMR) spectroscopy, and Fourier-transform infrared (FTIR)...

A simple pyrazoline-based ‘‘turn off’’ fluorescent sensor 5-(4-methoxyphenyl)-3-(5-methylfuran-2-yl)-1-phenyl-4,5-dihydro-1H-pyrazole (PFM) was synthesized and well characterized by different techniques such as FT-IR, ¹H-NMR, ¹³C-NMR, and mass spectrometry. The synthesized sensor PFM was utilized for the detection of Fe³⁺ ions. Fluorescence emissio...

Continuous release of pollutants into the environment poses serious threats to environmental sustainability and human health. For trace-level analysis of pollutants, layered double hydroxide (LDH) is an attractive option providing enhanced sorption capability and sensitivity toward pollutants because of its unique layered structure, tunable interio...

A molecularly imprinted fluorescence sensor built as a mesoporous structured silica imprinted layer on the surface of carbon dots ([email protected]) was employed for the selective detection of triclosan (TRI). The fluorescence intensity of this [email protected] was strongly quenched by triclosan via an electron transfer-induced fluorescence quenc...

The compound 17β-oestradiol (E2) is a steroidal oestrogen used extensively in food processing and animal husbandry. As E2 is well-known as a typical endocrine disrupting chemical, its release, penetration, and exposure create serious environmental concerns. Carbon dots (CDs) have attracted great attention due to their excellent fluorescent and non-...

A simple pyrazoline-based ‘‘turn off’’ fluorescent sensor 5-(4-methoxyphenyl)-3-(5-methylfuran-2-yl)-1-phenyl-4,5-dihydro-1 H -pyrazole (PFM) was synthesized and well characterized by different techniques such as FT-IR, ¹ H-NMR, ¹³ C-NMR, and mass spectrometry. The synthesized sensor PFM was utilized for the detection of Fe ³⁺ ions. Fluorescence em...

The integration of metal chalcogenide nanoparticles into MOFs to develop MOF@metal chalcogenide (MOF@MC) nanocomposites has gained significant interest for application in a variety of fields including sensing, photocatalysis, and energy. MOF-chalcogenide nanocomposites not only combine the advantages of the two materials but also display new and un...

A Schiff base bis(thiophen-2-yl-methylene)benzene-1, 4-diamine (L) was synthesized and used for selective and sensitive detection of Fe³⁺. L exhibited enhanced fluorescence response at excitation of 365 nm and emission wavelength of 440 nm for Fe³⁺. The formation of a 1:1 complex between L and Fe³⁺ was suggested by Job’s plot by fluorescence titrat...

Hollow porous molecularly imprinted polymers (HPMIPs) are regarded as promising adsorbents due to many advantageous properties such as large number of imprinted cavities, highly accessible binding sites, controllable pore structure, and fast mass transfer. This permits analyte molecules to readily access the recognition sites located inside the she...

Molecularly imprinted polymers have gained attention as an efficient sorbent media to remove organic contaminants from diverse environmental matrices. In this research endeavor, multi-template molecularly imprinted polymer (mt-MIP) was synthesized and utilized in solid phase extraction (SPE) as a sorption medium for trace analysis of three tricycli...

There is a dire need for development of efficient and sensitive methods for screening for parabens. In this research, we focused on quantification of four parabens (methylparaben (MP), ethylparaben (EP), propylparaben (PP), and butyl paraben (BP)) using chitosan intercalated nickel/iron layered double hydroxide (CS-Ni/Fe-LDH) composites as solid ph...

Using a co-precipitation method, starch-Mg/Al layered double hydroxide (S-Mg/Al LDH) composites were synthesized. Their physicochemical properties were assessed by Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and thermo-gravimetric analysis. The quantification of six non-steroidal anti-inflammatory drugs...

The PMIP-based SPE combined with HPLC-PDA method has shown substantial improvements in analytical performance due to the specific and potent binding sites for the PMIP adsorbent. The recovery and reusability of the PMIP-SPE technique were far superior compared with other options including the commercially available C18 cartridges based on our exper...

In light of the significant health hazards of organic dyes, it is imperative to develop a material that can efficiently remove diverse dyes from wastewater. In this study, the potential of DS-Zn/Al LDHs as a platform to treat various organic dyes was investigated. DS-Zn/Al LDHs proved to be an immensely efficient adsorbent for the elimination of BG...

A molecularly imprinted polymer (MIP) of carbamazepine (CBZ) was synthesized so as to facilitate the selective extraction of CBZ from aqueous and bio-samples by using a non-covalent imprinting approach. Synthesized materials were characterized with Fourier-transform infrared spectroscopy and scanning electron microscopy studies. The imprinted polym...

In this study, a quantum chemical model was developed to better account for the properties of a Schiff base, (Z)-1-(thiophen-2-yl-methyleneamino) propane-2-ol, which is derived from thiophene-2-carboxy aldehyde and 1-amino-2-propanol. To predict its molecular structure, the assignment of the vibrational wavelength (for FT-IR) and chemical shift (fo...

As the presence of organic dyes is recognized as cause of many environmental problems, it is important to develop an effective approach to efficiently remove diverse dyes from wastewater. To this end, dodecylsulfate–intercalated layered double hydroxides (DS-Zn/Al LDHs) were synthesized at a Zn/Al molar ratio (2:1) based on urea-hydrolysis followed...

Zn/Al-layered double hydroxides (LDHs) modified by sodium dodecylsulfate (SDS) were synthesized as a hydrophobic organic sorbent via urea hydrolysis. LDHs were applied as adsorbent for solid phase extraction (SPE) analysis to determine three alkylphenols (namely, p-tert-amylphenol (PTAP), p-cumylphenol (PCP), and p-n-octylphenol (POP)) in water sam...

Schiff bases and their metal complexes have become well-known for catalytic (e.g., in various synthetic processes) and biological properties (e.g., antifungal, antibacterial, anti-malarial, and antiviral characteristics) since their discovery by Hugo Schiff in 1864. As synthetic compounds, they are employed as versatile tools in diverse application...

Sample preparation before analytical studies using preconcentration techniques was the first step that should be at place. Various adsorbents has been used as a preconcentration and separation materials, among them recently Schiff bases are a promising candidate. Schiff base play a great role in detection of cation and anions coupling with differen...

The eco-friendly, facile, single pot synthesis, stability and applications of iron nanoparticles has aroused wide attention in the field of pollutant remediation. In present work, croton plant was chosen for the synthesis of iron nanoparticles. Croton is a medicinal plant and leaves extract of Croton sparsiflorus morong are rich source of secondary...

The supramolecular chemistry gives broad idea of intermolecular interactions where covalent bonds are not likely to form between the interacting species. Thus, interactions have been performed by host-guest interaction. Among the host molecule cyclodextrin seems to be the most promising to form the inclusion complexes with various guest molecules w...

The medicinal plants played an importance role throughout world and primarily used against for the treatment and prevention of number of diseases. Among the medicinal plants, Eucalyptus globulus, a diverse genus of flowering trees and shrubs belongs to the family Myrtaceae, commonly known as blue gum, cultivated in palni, Nilgiris, shimla hills, Pu...

Epilepsy is a neurological condition marked by frequent and unprovoked seizures. Antiepileptic drugs (AEDs) play a prominent role for treatment of epilepsy by achieving good control with medications. But, in past few decades, lot of studies shows that with the continuous release of these drugs into the environment, equally contributes them in a cat...

Depression is a common symptom in day to day life due to hectic life schedule. It is characterized by extended periods of dysphoria, feelings of meaninglessness and hopelessness. Depression causes ill health which give rise to other health problems like loss in productivity and lack of interest in work. It is associated with impaired balance of neu...

High performance liquid chromatography can separate metal ions that have same mass but different electronic configuration, thus act as a vital tool to separate complex mixtures, to resolve ions that may be indistinguishable by mass spectrometry alone. The main feature of this technique involves speciation of metal ions which has been briefly outlin...