Irma Salimović-BešićClinical Center University of Sarajevo · Clinical Microbiology
Irma Salimović-Bešić
Associate Professor
About
43
Publications
6,215
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
178
Citations
Citations since 2017
Introduction
Additional affiliations
February 2001 - February 2015
Education
October 2010 - June 2013
October 2001 - June 2003
September 1997 - June 2000
Slovak Academy of Sciences, Institute of Virology
Field of study
- The role of MN/CAIX protein-protein interactions in cancer cells
Publications
Publications (43)
Circulation of the Omicron variant with the reemergence of the N501Y mutation along with many others in the spike protein has once again stirred the academic community. Interestingly, tracing the genetic diversity of SARS-CoV-2 shed light on a less frequent N501Y+ Delta variant which has been in the global circulation for some time before the Omicr...
Phylogenetic analysis and mutation profile of HIV-1 G+CRF02_AG isolates in Bosnia and Herzegovina
A measles outbreak with two epidemic waves involving 4649 probable and laboratory-confirmed cases was recorded in six out of ten cantons of the Federation of Bosnia and Herzegovina between February 2014 and April 2015.The majority of the patients had never received measles vaccination (3115/4649, 67.00%) and the vaccination status of another 23% wa...
The objectives of this study were to identify human papillomavirus (HPV) genotypes in a group of Bosnian-Herzegovinian women with abnormal cytology and to assess their potential coverage by vaccines. HPVs were identified by multiplex real-time PCR test (HPV High Risk Typing Real-TM; Sacace Biotechnologies, Italy) of 105 women with an abnormal cervi...
This study compares the type-specific human papillomavirus (HPV) DNA test with E6/E7 mRNA detection assay because of their importance in cervical cancer screening programs. A total of 105 women with positive high-risk Hybrid Capture 2 or Abbott RealTime High Risk HPV screening test and an abnormal cervical Pap smear were enrolled in the study. HPV...
Performance characteristics and utilization of a rapid antigen-based test for SARS-CoV-2
Aim Phlebotominae sandflies are primary vectors of phleboviru-ses, causing the sandfly fever disease. The aim of this study was to detect and report the presence of flaviviruses in Phlebotominae sandflies captured in Bosnia and Herzegovina. Methods After a microscopic and morphometric analysis, the final identification of collected Phlebotomus spec...
Klebsiella pneumoniae is the second most prevalent gram-negative rod that causes nosocomial infections in hospitalized or otherwise immunocompromised patients. It can develop multiple drug resistance that results in limited treatment options and increased use of carbapenems. Various mechanisms are related to the development of carbapenem resistance...
Aim To present combined measles cases data and phylogenetic analysis of the virus circulated in 2018 in the Federation of Bosnia and Herzegovina (FB&H, the entity of Bosnia and Herzegovina), in order to analyse endemic transmission patterns of circulating strains and its implications for elimination efforts. Methods The data were derived from epide...
Aim This cross-sectional study of a group of women with abnormal cytology and high-risk human papillomavirus (hrHPV) infection compared genotyping HPV DNA and mRNA assays according to two age categories of women (S1: ≤30 and S2: >30 years).
Methods The hrHPV DNA positive results of 105 cervical samples of women were pooled and those harbouring HPV...
Evaluate serological testing for Lyme disease using two-step algorithm in our clinical laboratory.
In this study, novel hexa coordinated ruthenium(III) complex of the type Na[RuCl2L2)] (where L = monobasic bidentate Schiff base derived from the condensation of 5-nitrosalicyladehyde with aniline) has been synthesized and characterized by electrospray ionization time-of-flight mass spectrometry, infrared spectroscopy and ultraviolet/visible spectr...
Acinetobacter calcoaceticus-A. baumannii complex (ACB complex) is a nosocomial pathogen. Due to its high ability to develop antibiotic resistance, it has become a problematic challenge in the modern healthcare system. The molecular and genetic mechanisms of gaining multidrug resistance in ACB complex are well known. This study focuses on providing...
Presentation No.1035: HPV15-0727
Clinical Science -Clinical Aspects of Screening Tests: Application of diagnostics on the individual level
HPV DNA DETECTION WITH SIMULTANEOUS GENOTYPING OF HPV16 AND HPV18: INSIGHT INTO THE PROGNOSTIC VALUE AND POTENTIAL COVERAGE BY VACCINES
I. Salimovic-Besic 1, E. Dervovic 1, A. Dedeic-Ljubovic 1
1 University Cli...
EV1083
ePoster Viewing
- Virology non-HIV/non-hepatitis
The potential impact of climate conditions and catastrophic floods in Bosnia and Herzegovina on expanding hantavirus infection during April-September 2014
E. Dervovic1, I. Salimovic-Besic1, M. Seremet1, Z. Knezevic1, A. Dedeic-Ljubovic1, M. Hukic2,3
(1) University Clinical Centre- Sarajevo, S...
Between January 2014 and the beginning of February 2015, the Federal Institute of Public Health in the Federation of Bosnia and Herzegovina has reported 3,804 measles cases. Notable transmission has been observed in three Central Bosnia Canton municipalities: Bugojno, Fojnica and Travnik. Most cases were unvaccinated 2,680 (70%) or of unknown vacci...
A mumps outbreak reported from the Federation of Bosnia and Herzegovina involved 7,895 cases between December 2010 and September 2012. This was the largest outbreak in the country since the introduction of the measles, mumps and rubella vaccine in 1980. The highest disease incidence was found among 15 to 19 year-olds. About 39% (3,050/7,895) of cas...
Objectives. Recent data have shown the rotavirus as a major cause of acute viral gastroenteritis in Bosnia and Herzegovina. The aim of the study was to determine the distribution of norovirus, rotavirus and adenovirus during the Spring/Summer period and to specify the relationship between these infections and the age of patients. Methods. The study...
A rubella outbreak involving 1900 cases was recorded in the Federation of Bosnia and Herzegovina between mid-December 2009 and the end of May 2010. Sera from 389 suspected rubella cases were examined for the presence of rubella-specific IgM and IgG antibodies. A total of 32 throat swabs from suspected rubella cases were tested by RT-PCR and were us...
The countries of the Balkan Peninsula have become the region with frequent outbreaks of the emerging and re-emerging diseases during the last decade of the 20th and the first decade of the 21st century. The majority of outbreaks were wildlife zoonotic, and vector-borne diseases, such as brucellosis, leptospirosis, listeriosis, tularemia, Q-fever, L...
The countries of the Balkan Peninsula have become the region with frequent outbreaks of the emerging and re-emerging diseases during the last decade of the 20th and the first decade of the 21st century. The majority of outbreaks were wildlife zoonotic, and vector-borne diseases, such as brucellosis, leptospirosis, listeriosis, tularemia, Q-fever, L...
Sandfly fever viruses (SFV) are endemic in the Mediterranean, Middle East, northern African and western Asian countries. Toscana virus (TOSV), serotype of Sandfly fever Naples virus, is among of the three most prevalent viruses associated with meningitis during the warm seasons in northern Mediterranean countries. The historical data of the sandfly...
Purpose: Relative importance of the different enteropathogens depends on geographical
location and season of study. Identification of gastroenteritis viruses seasonally
distributed in Bosnia and Herzegovina was the aim of the study. Methods:
Stool specimens of 544 patients with acute gastroenteritis were examined by direct
electron microscopy (rota...
Objective: Acute diarrhea diseases are a major cause of morbidity in
children through the world. The most important and dominate of viruses
is Rotavirus of the viral family Reoviridae. Estimated that each year 25
million children before age 5 with rotavirus gastroenteritis, clinic visits,
2 million hospitalizations, and 600. 000 died. Preliminary e...
[corrected] The choice of diagnostic tool for the detection of oncogenic HPV types affects in a great manner on the uterine cervical carcinoma prevention in women with early stage of cervical dysplasia.
In this study 148 women with three subsequent cervical cytologic tests within two years showing mild dyskaryosis (Pap II) were enrolled. HPV infect...
Molecular epidemiology studies have shown that some types of HPV are causally linked with precancerous lesions of cervix and invasive cervical cancer. In our study, we enrolled HPV infected women with repeated Pap smears (Pap II) in Slovenia and verified HPV infection. HPV genotypes were determined using the method of enzyme restriction of PCR prod...
Seasonal distribution of gastroenteritis viruses in Bosnia and Herzegovina during 2002/2003
Abstract number: 1135_237
Salimovic- Besic I., Hukic M., Dervovic E.
Objective:
The relative importance of the different enteropathogens depends on a variety factors. Some of them are geographical location and season of study.
Methods:
547 stool specime...
In the detection of precancerous lesions the cervical Papanicolaou smear screening is used in Slovenia and worldwide. Management of patients with repeat abnormal smears (Pap II) represents a great and complex clinical and public health problem. Repeated cytologic examinations are routine procedure in many countries, also in Slovenia, although the s...
Projects
Projects (2)
Project holder: Clinical Center of the University of Sarajevo, Bosnia and Herzegovina. The project is financially supported by the Federal Ministry of Education and Science, Bosnia and Herzegovina. Contract No. 01-04-11936-1 (KCUS), 05-35-1809-1/21 (FMNO).
Ciljevi realizacije ove studije su usmjereni na određivanje onkogene aktivnosti visoko-rizičnih genotipova HPV-a, detekcijom transkripta (mRNA) virusnih onkogena E6 i E7, kod grupe žena sa potvrđenom HPV infekcijom i prekanceroznim promjenama na grliću materice. U ovom istraživanju ćemo:
Odrediti zastupljenost HPV genotipova (HPV16, HPV18, HPV31, HPV33, HPV45) u istraživanoj grupi pacijentica.
Ispitati povezanost HPV genotipa sa starosnom dobi pacijentica.
Ispitati povezanost HPV genotipa sa citološkom dijagnozom pacijentica.
Na uzorcima pacijentica sa detekovanom visoko-rizičnom HPV infekcijom izvesti test detekcije onkogene aktivnosti visoko-rizičnih HPV tipova (HPV16, HPV18, HPV31, HPV33, HPV45).
Ispitati povezanost testa za određivanje onkogene aktivnosti HPV-a i HPV DNA skrining testa s obzirom na citološku dijagnozu pacijentica.
Ispitati međusobnu povezanost u ekspresiji virusnih onkogena E6 i E7 pojedinačnih visoko-rizičnih HPV tipova sa citološkom dijagnozom.
Izvršiti evaluaciju rezultata dobivenih sa testovima tri različita proizvođača, zasnovana na različitim principima molekularne dijagnostike (Hybrid Capture 2 HPV DNA test, Qiagen, Njemačka; RealTime High Risk HPV Assay, Abbott Diagnostics, Njemačka i NucliSENS Easy Q® HPV v1.1, bioMérieux SA, Francuska), a u svrhu izrade dijagnostičkog protokola HPV infekcije, koji će biti preporučen za rutinsku upotrebu.
