Iria Seoane-Viaño- PhD
- PostDoc Position at University of Santiago de Compostela
Iria Seoane-Viaño
- PhD
- PostDoc Position at University of Santiago de Compostela
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22
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Publications (22)
Despite the high success rates of dental implants, peri-implantitis is currently the most common complication in regard to dental implantology. Prophylaxis and different treatment methods, such as local and systemic antibiotics and antiseptic treatments, have been widely discussed in recent decades, and surgical and nonsurgical techniques present b...
Despite the high success rates of dental implants, peri-implantitis is currently the most common complication in dental implantology. Peri-implantitis has an inflammatory nature, it is associated with the accumulation of plaque in the peri-implant tissues, and its evolution can be progressive depending on various factors, comorbidities, and poor or...
Three-dimensional (3D) printing technologies have gained increased attention in the manufacture of pharmaceuticals in recent years. These rapid prototyping technologies have a wide range of applications, from the manufacturing of personalised printlets (3D printed tablets) to medical devices and 3D bioprinting of living tissues. In the pharmaceutic...
Chronic retinal diseases, such as age-related macular degeneration (AMD), are a major cause of global visual impairment. However, current treatment methods involving repetitive intravitreal injections pose financial and health burdens for patients. The development of controlled drug release systems, particularly for biological drugs, is still an un...
Pharmaceutical 3D printing (3DP) is one of the emerging enabling technologies of personalised medicines as it affords the ability to fabricate highly versatile dosage forms. In the past 2 years, national medicines regulatory authorities have held consultations with external stakeholders to adapt regulatory frameworks to embrace point-of-care manufa...
Inkjet printing has been extensively explored in recent years to produce personalised medicines due to its low cost and versatility. Pharmaceutical applications have ranged from orodispersible films to complex polydrug implants. However, the multi-factorial nature of the inkjet printing process makes formulation (e.g., composition, surface tension,...
Inkjet printing has the potential to advance the treatment of eye diseases by printing drugs on demand onto contact lenses for localised delivery and personalised dosing, while near-infrared (NIR) spectroscopy can further be used as a quality control method for quantifying the drug but has yet to be demonstrated with contact lenses. In this study,...
Recent advancements in next generation spacecrafts have reignited public excitement over life beyond Earth. However, to safeguard the health and safety of humans in the hostile environment of space, innovation in pharmaceutical manufacturing and drug delivery deserves urgent attention. In this review/commentary, the current state of medicines provi...
Diabetes mellitus is a major health problem with increasing prevalence at a global level. The discovery of insulin in the early 1900s represented a major breakthrough in diabetes management, with further milestones being subsequently achieved with the identification of glucagon-like peptide-1 (GLP-1) and the introduction of GLP-1 receptor agonists...
Three-dimensional (3D) printing is a revolutionary technology that is disrupting the pharmaceutical development by enabling the production of personalised printlets (3D printed drug products) on demand. By creating small batches of dose flexible medicines, this versatile technology offers significant advantages for clinical practice and drug develo...
Three-dimensional (3D) printing is an innovative additive manufacturing technology, capable of fabricating unique objects in a layer-by-layer manner. Semi-solid extrusion (SSE) is a subset of material extrusion 3D printing, based on the sequential deposition of layers of gel or paste to create an object of a desired size and shape. In comparison to...
The manufacture of pharmaceutical products is moving toward the production of smarter and more personalized drug delivery devices, more cost-effective, and with better outcomes for the patients. The era of “one-size-fits-all” approach is coming to an end, and three-dimensional printing (3DP) technology is forecast to revolutionize the medicine manu...
The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an experimental model of inflammatory bowel disease. Blends of Gelucire 44/14 and coconut oil were employed as lipid excipients to obtain suppository formulations with self...
Ulcerative colitis is a global health problem, affecting millions of individuals worldwide. As an inflammatory condition localised in the large intestine, rectal delivery of immunosuppressive therapies such as tacrolimus is a promising strategy to maximise drug concentration at the site of action whilst minimising systemic side effects. Here, for t...
Following oral administration, gastric emptying is often a rate-limiting step in the absorption of drugs and is dependent on both physiological and pharmaceutical factors. To guide translation into humans, small animal imaging during pre-clinical studies has been increasingly used to localise the gastrointestinal transit of solid dosage forms. In c...
Inflammatory Bowel Disease (IBD) is a group of chronic disorders of the gastrointestinal tract, which two main types are Crohn’s disease and ulcerative colitis. Although conventional therapeutic strategies have demonstrated to be effective in the IBD treatment, it is necessary to incorporate novel therapeutic agents that target other mechanisms inv...
Inflammatory bowel disease (IBD) is a group of chronic disorders of the gastrointestinal (GI) tract, which two main types are Crohn´s disease (CD) and ulcerative colitis (UC). The exact causes of IBD still remain unknown but are accepted to be multifactorial. For this reason, the use of animal models of IBD is gaining importance in preclinical rese...
Crohn’s disease (CD) and ulcerative colitis (UC) are the two main types of an autoimmune disease called Inflammatory Bowel Disease (IBD). Since the beginning of the 21st century, IBD has become a global disease with an increasing incidence in newly-industrialized countries whose societies have become Westernized. Although in Europe and North Americ...
Inflammatory bowel disease (IBD) is a group of chronic disorders of the gastrointestinal tract, which two main types are Crohńs disease and ulcerative colitis. It has multifactorial etiologies, being essential the use of animal models and disease activity measures to develop new therapies. With this aim, the use of animal models in combination with...
