Irami Araújo-Filho

Irami Araújo-Filho
Universidade Federal do Rio Grande do Norte | IIP · Departamento de Cirurgia

Ph.D. in Health Science
http://lattes.cnpq.br/3975706297235540 / https://scholar.google.com.br/citations?user=nyBjpccAAAAJ&hl=pt-BR/irami

About

300
Publications
119,190
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744
Citations
Citations since 2016
231 Research Items
535 Citations
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
Additional affiliations
December 2005 - present
Universidade Federal do Rio Grande do Norte
Position
  • Professor (Associate)
Description
  • http://lattes.cnpq.br/3975706297235540
Education
March 1994 - September 2007
Universidade Federal do Rio Grande do Norte
Field of study
  • MEDICINE COURSE/SURGERY/EXPERIMENTAL SURGERY/MASTER/Ph.D

Publications

Publications (300)
Research
Full-text available
Irami Araujo Filho por superar as expectativas da instituição, quanto ao seu desempenho como gestor no ano de 2020, um ano tão desafiador e de muitas adaptações. A sua dedicação contribuiu significativamente para o bom andamento da nossa missão de: "educar, produzir e disseminar o saber universal, preservar e difundir as artes e a cultura, e contri...
Article
Full-text available
Background: Hodgkin lymphoma (HL) is a rare lymphoproliferative disorder that occurs in about 10% of all cancer cases. Human immunodeficiency virus (HIV) is associated with an increased occurrence of a wide range of cancers, including HL due to progressive immunosuppression and co-infection with oncogenic viruses. However, the aim of this systemat...
Article
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Introduction: Cholecystectomy is the intervention of choice for treating acute cholecystitis; when conservative management does not work, it operates on the patient outside the critical condition. It can be performed together with or after endoscopic papillotomy through endoscopic retrograde cholangiopancreatography (ERCP) when it is concurrent wi...
Chapter
Full-text available
The management of chronic wound comprises an important aspect of medical practice and in most cases, requires specific treatment for its success. Historical records revealed that copaiba oil had been used primarily to promote wound healing and treat inflammatory and infectious diseases. However, the low solubility in water has limited its pharmacol...
Chapter
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The rapid closure of the lesion, known as wound healing, is considered the main step within the wound management treatment. An efficient wound healing process leads to a functional and aesthetically satisfactory scar as a result of a reduced microbial contamination and accelerated healing process. Among the wound treatment modalities, the use of wo...
Chapter
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The Brazilian biodiversity is considered one of the most promising sources of biomolecules, especially those related with the impressive biological activities and potent pharmacological effects observed not only at the Brazilian Amazon region, but also at the Brazilian Savana and Brazilian Atlantic Forest, where a huge biodiversity still being disc...
Article
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Introduction: Surgical meshes are common in peritoneostomies to control damage and reduce mortality in critically ill patients. The use of chitosan provides anti-adherence to the polypropylene mesh and the addition of antibiotics reduces the rate of infections. Objective: To create and test biocompatible film involving chitosan associated or not wi...
Article
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Objective: This study aimed to investigate the effect of A. chica extract on the evolution of experimental rectocolitis in rats, and the expression of the pro-inflammatory cytokines TNF-a, IL-1β and IL-6 in colonic tissue. Methods: Wistar rats weighing 275±23g were distributed into 4 groups of 6 animals each. Rectocolitis was induced in rats by rec...
Article
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The use of mobile phones has dramatically increased all over the world. Such revolution in the communication amongst individuals has a great impact in patient care, supporting their self-management and promoting shared responsibility with health services. Given that improved communication facilitates compliance with scheduled procedures and reduc...
Article
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Introduction: Vitamin D is synthesized from 7-dehydrocholesterol during a photochemical reaction, under the effect of ultraviolet radiation on the skin, obtained from food. It is hydroxylated in the liver to 25-hydroxyvitamin D3 (25(OH)D3). It is an active metabolite, which maintains the balance of calcium and phosphorus concentration in the blood,...
Article
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To analyze the pathophysiological aspects of lupus mastitis (LM), clinical presentation, epidemiology, radiological and histological findings, and treatment, to disseminate it to the academic community and draw attention to this pathology as one of the differential diagnoses in the management of breast lesions in males, especially in the case of br...
Article
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In the testicles, the expression of Angiotensin-Converting Enzyme 2 receptors makes it more susceptible to infection by Sars-CoV-2 and, therefore, to male infertility with significant health problems for the patient. Therefore, this study aimed to analyze the clinical pathophysiology and the mechanisms involved in the genesis of male infertility fr...
Article
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Hypertensive patients with COVID-19 are susceptible to complications of the disease, so this study aimed to analyze the action of drugs that act on Angiotensin (TA) in the presence of COVID-19 in comparison with other antihypertensives, as well as to identify the main ones. evidence on the subject presented so far. It is an integrative literature r...
Article
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Temporomandibular Disorder (TMD) is a pathology of the stomatognathic system characterized by a set of clinical disorders that includes a temporomandibular joint, a masticatory musculature and associated structures. It is the most common orofacial pain condition of non-dental origin and which is increasing among adults in the age group between 18 a...
Article
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The rapid spread of coronavirus disease (COVID-19) worldwide urges the need for studies on the illness and its management. The COVID-19 infection leads to hypercoagulation due to inflammatory cytokine release and D-dimer increase in critically ill patients, resulting in pulmonary thromboembolism (PE) and venous thromboembolism (VTE) evolving to sep...
Article
Background and objective: The growth of the urban population exerts considerable pressure on municipalities' public managers to focus their attention on providing emergency medical care that meets the growing demand for emergency pre-hospital medical care. Currently, there are a significant number of traffic accidents and other serious occurrences...
Patent
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A presente invenção refere-se a um bioformulado denominado de MEOCOG, isento de efeito adverso, que contém óleo de copaíba (OC) veiculado em baixa concentração, em mistura com um estabilizante natural e um tensoativo biológico da classe dos sorbitanos. Dentre os estudos realizados, destacam-se: análises de cromatografia em fase gasosa de alta resol...
Patent
Full-text available
A presente invenção, situada no campo da biotecnologia, refere-se a um sistema nanoestruturado, especificamente, uma nanoemulsão contendo componentes naturais, preferencialmente, óleo de copaíba (OC) veiculado em meio salinizado com água de coco em pó (ACP), na presença de um tensoativo da classe dos sorbitanos. Este formulado possibilitou a solubi...
Patent
Full-text available
A presente invenção, situada no campo da biotecnologia, refere-se a um sistema nanoestruturado, especificamente, uma nanoemulsão contendo componentes naturais, preferencialmente, óleo de copaíba (OC) veiculado em meio salinizado com água de coco em pó (ACP), na presença de um tensoativo da classe dos sorbitanos. Este formulado possibilitou a solubi...
Patent
Full-text available
O extrato hidroalcolólico (EHA) obtido das cascas do caule da espécie medicinal Croton cajucara Benth (Euphorbiaceae), foi biodisponibilizado, para uso oral, no sistema coloidal MEHA (sistema automicroemulsificante contendo o extrato EHA de C. cajucara). A solubilização do extrato EHA na microemulsão MEHA, resultou na produção do fitoterápico MEHA...
Patent
Full-text available
Na presente invenção objetivou-se a veiculação do óleo de copaíba (OC) em baixa concentração, com indicação terapêutica odontológica. Para tanto, obteve-se um sistema automicroemulsionado do tipo SMEDDS, contendo um tensoativo da classe dos sorbitanos e fase oleosa rica em OC. O bioproduto resultante foi denominado de BIOCOPAME e sua caracterização...
Patent
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A presente invenção está situada na área da biotecnologia e refere-se ao processo de preparo, veiculação e avaliação terapêutica de bioformulados a base de Morinda citrifolia (noni). Inicialmente foram obtidos extratos hidroalcoólicos de diferentes partes do fruto de noni (polpa, semente, casca e misturas de polpa e semente). Um sistema autonanomul...
Patent
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No presente invento, amostras de óleo de copaíba (OCP) das espécies Copaifera reticulata Ducke (OCPR), Copaifera multijuga Hayne (OCPM) e de uma amostra comercial (OCPC), foram veiculadas (0,5% - 3,0%) em nanoemulsão SNEDDS (self-nanoemulsifying drug delivery system), para uso tópico associado com Laser de baixa intensidade (LLLT), 660nm, 4 j/cm²,...
Patent
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O presente invento consiste no preparo de uma formulação cicatrizante para uso tópico em feridas, desenvolvida a base de biofilme de quitosana (QUIT) associado a uma nanoemulsão carreadora do extrato hidroalcoólico obtido das cascas do caule de Croton cajucara Benth (EHA-CC). O polímero QUIT por apresentar biocompatibilidade, biodegradabilidade, se...
Article
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The world panorama of disseminating the new coronavirus SARS-CoV-2 is considered a pandemic by the World Health Organization (WHO) with the risk of complications due to the imbalance of immune responses. The present study evaluated whether the use of corticosteroids has scientifically proven efficacy in treating patients with the severe form of COV...
Research
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Background The growth of the urban population exerts considerable pressure on municipalities’ public managers to focus their attention on providing emergency medical care that meets the growing demand for emergency pre-hospital medical care. Currently, there are a significant number of traffic accidents and other serious occurrences, such as heart...
Article
Full-text available
Extracellular vesicles (EVs), especially from stem/stromal cells (SCs), represent a cell-free alternative in regenerative medicine holding promises to promote tissue healing while providing safety and logistic advantages in comparison to cellular counterparts. Herein, we hypothesize that SC EVs, administered locally in a thermoresponsive gel, is a...
Technical Report
Full-text available
Irami Araujo Filho por superar as expectativas da instituição, quanto ao seu desempenho como gestor no ano de 2019, contribuindo significativamente para a melhoria da UFRN e cumprimento da sua missão de: "educar, produzir e disseminar o saber universal, preservar e difundir as artes e a cultura, e contribuir para o desenvolvimento humano, compromet...
Article
Full-text available
Purpose: The hospital is an organization that has its own characteristics that differentiate it from other institutions. It is characterized as a company providing services of social purpose, with a great operational complexity, due to the diversity of services provided. These organizations are dependent on technology to play the role of assisting...
Article
Full-text available
The attempt to repair skin wounds dates back many years. We have observed bone fragments for making needles, hair, fibers, and animal tissues as sutures and even applying sensors to accelerate the healing process throughout history. Despite all the developments, the need for a qualified professional and prior local anesthesia to perform the suture...
Article
Full-text available
COVID-19 disease is a pandemic, with severe clinical manifestations, high lethality and which has reached at least 128 countries. In this sense, the bioprotection of health professionals is a fundamental principle in preserving the lives of those who work in the direct care of patients who are victims of SARS-CoV-2. Each day the number of confirmed...
Article
Full-text available
The growth of the urban population exerts considerable pressure on municipalities’ public managers to focus their attention on providing emergency medical care that meets the growing demand for emergency pre-hospital medical care. It is estimated that, by 2050, urban areas should have a population of 6.29 billion people, equivalent to 69% of the wo...
Article
Full-text available
Guanosine (GUO) is an endogenous guanine nucleoside to which several neuroprotective and neurotrophic effects have been attributed in experimental in vitro and/or in vivo models of central nervous system (CNS) diseases, including ischemic stroke, Alzheimer's, Parkin-son's disease, spinal cord injury, nociception and depression. The objective of thi...
Article
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The coronavirus pandemic transformed the world abruptly due to the speed of transmission and high morbidity and mortality. Many deaths have been quantified, and the scientific community intensifies the search for molecular targets, protein sequences and polymorphismson SARS-CoV-2, to improve the clinical evolution and survival of patients. Initiall...
Article
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SARS-CoV-2, a severe acute respiratory syndrome caused by Coronavirus 2, discovered in 2019 in China, is responsible for the current pandemic declared by the WHO since March 2020. The clinical syndrome caused by Covid-19 has a broad spectrum of severity. The most common clinical manifestations are fever, dry cough, dyspnea, fatigue, and anosmia. Th...
Article
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The clinical syndrome caused by SARS-CoV-2 was called COVID-19 and became a pandemic from March 2020. Fever, dry cough, and dyspnoea are the predominant clinical manifestations of the disease. However, symptoms such as diarrhea, nausea, vomiting, and abdominal discomfort can also be found in infected patients. Despite the increased prevalence since...
Article
Full-text available
COVID-19 disease is a pandemic, with severe clinical manifestations, high lethality and which has reached at least 128 countries. In this sense, the bioprotection of health professionals is a fundamental principle in preserving the lives of those who work in the direct care of patients who are victims of SARS-CoV-2. Each day the number of confirmed...
Article
Full-text available
O trauma cirúrgico produz disfunção imunológica profunda. As estratégias terapêuticas direcionadas à restauração da homeostase devem ter como objetivo corrigir ou desequilibrar o fisiológico pró-inflamatório e anti-inflamatório associado a cirurgias de grande porte. Cada vez mais, foi comprovada a influência das cirurgias laparoscópicas para a redu...
Patent
Full-text available
71) Depositante(es): MARIA APARECIDA MEDEIROS MACIEL. (72) Inventor(es): MELYSSA LIMA DE MEDEIROS; JOHERBSON DEIVID DOS SANTOS PEREIRA; BERNARDO BRUNO DIAS BARACHO; MAGNALDO INÁCIO TAVARES MEDEIROS; IRAMI ARAÚJO FILHO; VALDIR FLORÊNCIO DA VEIGA JUNIOR; MILENA CAMPELO FREITAS DE LIMA; RICARDO LUIZ CAVALCANTI DE ALBUQUERQUE JÚNIOR; LIVIA DOS ANJOS TA...
Technical Report
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As a general surgeon, I never thought of research in my field. What I liked was to operate and is in the operating room. It was through my professor and master and doctoral advisor that I discovered the possibility of researching surgery. I learned that through research in medicine, we could evaluate established treatments, scientifically validate...
Article
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Introduction: Technological advances in imaging studies have led to an increase in early diagnosis of benign and focal liver tumors such as simple cyst, hemangioma, focal nodular hyperplasia (UFH), adenoma. Objective: To evaluate the prevalence of benign liver lesions in the largest reference center for hepatology in the Rio Grande do Norte - Unive...
Article
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Background: Therapy for the Hepatitis C Virus (HCV) has undergone a revolution with the introduction of Direct-Acting Antivirals (DAA). DAAs achieve Sustained Virological Response (SVR) in 90-95% of treated patients, compared to 50-70% of those receiving dual pegylated interfere on and ribavir in therapy. Although they are already available, there...
Article
Full-text available
1. Abstract Hepatocellular carcinoma is the most common primary malignant tumor of the liver. Cirrhosisis associated with its carcinogenesis, so periodic surveillance is necessary. Ultrasonography is currently the most appropriate test for screening hepatocellular carcinoma, and alpha-fetoprotein is the most used biomarker despite its low sensitivi...
Article
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A pesquisa tem como objetivo avaliar a resiliência de adolescentes participantes e não participantes de projetos sociais esportivos relacionando-a ao seu perfil sociodemográfico. Estudo de corte transversal, comparativo e analítico, abrangeu 134 adolescentes, com faixa etária compreendida de 12 a 17 anos, residentes em zona de alta vulnerabilidade...
Article
Full-text available
The aim of this study was to evaluate the resilience of adolescents participants and non-participants of social projects for sports relating it to their sociodemographic profile. Cross-section Study, comparative and analytical, covered 134 adolescents, from ages 12 to 17, residing in a social zone of high vulnerability in a Northeastern Brazilian c...
Chapter
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Current therapies for neurodegenerative diseases offer only limited benefits to their clinical symptoms and do not prevent the degeneration of neuronal cells. Neurological diseases affect millions of people around the world, and the economic impact of treatment is high, given that health care resources are scarce. Thus, many therapeutic strategies...
Chapter
Full-text available
Current therapies for neurodegenerative diseases offer only limited benefits to their clinical symptoms and do not prevent the degeneration of neuronal cells. Neurological diseases affect millions of people around the world, and the economic impact of treatment is high, given that health care resources are scarce. Thus, many therapeutic strategies...
Article
Full-text available
Purpose: Evaluate the knowledge regarding the theoretical calculation of refractometry among professionals who prescribe eyeglass lenses and develop a new simulator application to assist them in this task. Methods: A questionnaire was developed and answered by 51 randomly selected professionals with the purpose of evaluating their level of knowledg...
Article
Full-text available
Hepatocellular carcinoma (HCC) is the sixth most common cause of cancer in the world, with more than 740,000 cases/year. Hepatocellular carcinoma is related to chronic liver diseases (hepatitis B, C, cirrhosis). Treatment of HCC is variable and may or may not be successful. After treatment, the patient is followed up to prevent and diagnose recurre...
Article
Full-text available
Introduction: Injury to the cord spinal is a complex medical disease, associated with a serious and disabling incapacity in life, predisposing to a systemic dysfunc-tion that must lead to a secondary process, with a high risk of death. Objective: The objective of this study was to analyze the effects of sciatic nerve fragmentation in the presence o...
Article
Full-text available
Introduction: Recently, an expressive interest has developed about the importance of the condition known as male climacte-ric or andropause. In men this process is not universal, occurring in a portion of the male population with clinical manifestations that are more gradual than those occurring in menopausal women. Objective: The present study aim...