Ionela Andreea Neacsu

Ionela Andreea Neacsu
Polytechnic University of Bucharest | UPB · Department of Science and Engineering of Oxide Materials and Nanomaterials

Doctor of Engineering

About

36
Publications
7,251
Reads
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325
Citations
Introduction
Ionela Andreea Neacsu currently works at the Department of Science and Engineering of Oxide Materials and Nanomaterials, Polytechnic University of Bucharest. Their most recent publication is Iron Oxide–Silica Core–Shell Nanoparticles Functionalized with Essential Oils for Antimicrobial Therapies.
Additional affiliations
October 2015 - October 2020
Polytechnic University of Bucharest
Position
  • Professor (Assistant)
Education
October 2015 - October 2019
University Politehnica of Bucharest
Field of study
  • Biomaterials for tissue regeneration
March 2015 - June 2015
Linköping University
Field of study
  • Physics, Chemistry, and Biology
October 2013 - July 2015
University Politehnica of Bucharest
Field of study
  • Micro and nanomaterials

Publications

Publications (36)
Article
Full-text available
The current trend in antimicrobial-agent development focuses on the use of natural compounds that limit the toxicity of conventional drugs and provide a potential solution to the antimicrobial resistance crisis. Curcumin represents a natural bioactive compound with well-known antimicrobial, anticancer, and antioxidant properties. However, its hydro...
Article
Full-text available
This research aims to synthesize hydroxyapatite powders from a biogenic calcium source (hen eggshell) and study the effect of two maturation methods (a classical method and a combined short time maturation at 135°C in microwave-assisted hydrothermal conditions) on its final properties. The synthesized specimens consist of nanometric polycrystalline...
Article
Full-text available
In recent years, the number of people needing bone replacements for the treatment of defects caused by chronic diseases or accidents has continuously increased. To solve these problems, tissue engineering has gained significant attention in the biomedical field, by focusing on the development of suitable materials that improve osseointegration and...
Article
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In recent years, biomaterials development and characterization for new applications in regenerative medicine or controlled release represent one of the biggest challenges. Tissue engineering is one of the most intensively studied domain where hydrogels are considered optimum applications in the biomedical field. The delicate nature of hydrogels and...
Article
Full-text available
In this paper, the thermal decomposition of crystalline Al(OH)3 was studied over the temperature range of 260–400 °C for particles with a size between 10 and 150 µm. The weight losses and thermal effects occurring in each of the dehydration process were assessed using thermogravimetry (TG) and differential scanning calorimetry (DSC) thermal analysi...
Article
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Recent years have witnessed a tremendous interest in the use of essential oils in biomedical applications due to their intrinsic antimicrobial, antioxidant, and anticancer properties. However, their low aqueous solubility and high volatility compromise their maximum potential, thus requiring the development of efficient supports for their delivery....
Article
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This research focused on the synthesis of apatite, starting from a natural biogenic calcium source (egg-shells) and its chemical and morpho-structural characterization in comparison with two commercial xenografts used as a bone substitute in dentistry. The synthesis route for the hydroxyapatite powder was the microwave-assisted hydrothermal techniq...
Article
Full-text available
Aluminum hydroxide is an essential material for the industrial production of ceramics (especially insulators and refractories), desiccants, absorbents, flame retardants, filers for plastics and rubbers, catalysts, and various construction materials. The calcination process of Al(OH)3 first induces dehydration and, finally, results in α-Al2O3 format...
Article
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Microbial infections associated with skin diseases are frequently investigated since they impact on the progress of pathology and healing. The present work proposes the development of freeze-dried, glutaraldehyde cross-linked, and non-cross-linked biocomposite dressings with a porous structure, which may assist the reepithelization process through...
Article
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Hydroxyapatite (HAp) and bacterial cellulose (BC) composite materials represent a promising approach for tissue engineering due to their excellent biocompatibility and bioactivity. This paper presents the synthesis and characterization of two types of materials based on HAp and BC, with antibacterial properties provided by silver nanoparticles (AgN...
Article
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This paper proposes the development of a biomimetic composite based on naturally derived biomaterials. This freeze-dried scaffold contains a microwave-synthesized form of biomimetic hydroxyapatite (HAp), using the interwoven hierarchical structure of eggshell membrane (ESM) as bio-template. The bone regeneration capacity of the scaffold is enhanced...
Article
Full-text available
The aim of this study was to develop and characterize composite materials based on collagen, hydroxyapatite and eugenol acetate as new filler biomaterial for the reconstruction of the tissue damage arising after the resection in case of bone cancer. Composite gels consisting of collagen and hydroxyapatite in different proportions (Coll:HAp-100:0; 7...
Article
Full-text available
In this work, valuable biocompatible Ag/Fe-enhanced TiO2 nanoparticles are comparatively prepared by a conventional wet chemistry method (sol-gel) and a rapid, efficient, hybrid unconventional method (microwave-assisted hydrothermal synthesis). In order to establish their application as effective compounds in sunscreens, the obtained powders were f...
Article
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This paper aims to improve medical strategies regarding cancer treatment, by developing new targeted cancer therapy nanostructured systems, based on magnetite and natural catabolism products as coating agents (glutamic acid, tartaric acid), with induced cellular internalization. In order to create hydrophilic, biocompatible systems, suitable for ta...
Article
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This paper is focused on the basic properties of ceramic composite materials used as thermal barrier coatings in the aerospace industry like SiC, ZrC, ZrB2 etc., and summarizes some principal properties for thermal barrier coatings. Although the aerospace industry is mainly based on metallic materials, a more attractive approach is represented by c...
Article
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Surface modification of zinc oxide nanoparticles (ZnO NPs) is a strategy to tune their biocompatibility. Herein we report on the synthesis of a series of fluorescent ZnO NPs modified with 2–10% (3-glycidyloxypropyl)trimethoxysilane (GPTMS) to investigate the fluorescence properties and to explore their applications in microbiology and biomedicine....
Thesis
The present thesis aims to present different synthesis routes and characterization techniques in order to design both bone and skin tissue regeneration materials with enhanced properties in terms of antimicrobial effect and biocompatibility requirements. Hydroxyapatite and its derivatives provide biocompatibility and promote the bone regeneration p...
Article
Full-text available
The purpose of this study was the synthesis of two types of biodegradable materials with synthetic polymers (PLGA) or natural polymers (collagen) and hydroxyapatite, followed by determination of the encapsulation percentage of the drug in the polymer. Regardless of the chosen method, the percentage of the encapsulated drug was found to be quite hig...
Article
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Luminescent europium-doped hydroxylapatite (EuXHAp) nanomaterials were successfully obtained by co-precipitation method at low temperature. The morphological, structural and optical properties were investigated by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier Transform Infrared (FT-IR),...
Article
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The most important properties of performant wound dressings are biocompatibility, the ability to retain large amount of exudate and to avoid complications related with persistent infection which could lead to delayed wound healing. This research aimed to obtain and characterize a new type of antimicrobial dressings, based on zinc oxide/sodium algin...
Article
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Background and objectives: In the last few years, graphene oxide has attracted much attention in biomedical applications due to its unique physico-chemical properties and can be used as a carrier for both hydrophilic and/or hydrophobic biomolecules. The purpose of this paper was to synthesize graphene oxide and to obtain multifunctional platforms b...
Article
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Synthesis of biomimetic materials for implants and prostheses is a hot topic in nanobiotechnology strategies. Today the major approach of orthopaedic implants in hard tissue engineering is represented by titanium implants. A comparative study of hybrid thin coatings deposition was performed by spin coating and matrix-assisted pulsed laser evaporati...
Article
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One new, promising approach in the medical field is represented by hydroxyapatite doped with luminescent materials for biomedical luminescence imaging. The use of hydroxyapatite-based luminescent materials is an interesting area of research because of the attractive characteristics of such materials, which include biodegradability, bioactivity, bio...
Article
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The purpose of this study was to obtain and characterize composite hydroxyapatite and graphene oxide-based materials for subsequent bone tissue regeneration applications. Synthesis of pure hydroxyapatite and samples with variable graphene oxide content were performed by microwave assisted hydrothermal method, thus obtaining dimensional homogeneous...
Article
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Although engineered silver (Ag) nanopowders offer great promise in various fields of biomedical, industrial and ecological applications, insufficient data is known about their cytotoxicity. The purpose of the present study was the synthesis and then the determination of cytotoxicity effect of Ag powders using the pyrosol method, at various temperat...
Article
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The aim of this study was to synthesize and characterize a ceramic material with a high porosity, which can be used as a support for the microorganisms' colonies for water purification. Given the target application, in order to obtain a composition of the ternary system MgO-Al2O3-SiO2, there were selected two natural materials: kaolin and talc powd...
Article
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In this review are highlighted the corrosion and biocompatibility of biodegradable Mg alloys for their use in orthopedic applications. It was revealed that mixing with alloying elements, such as Mn and Zn, provides improved corrosion resistance to Mg alloys; this pursuit is built on the fact that Mg and its alloys are degradable through their time...
Article
Full-text available
In this work, several nanostructures (nanopowders and nanostars) of undoped and 1%, 3% and 5% europium (Eu3+)-doped ZnO have been synthesized via coprecipitation method using oxalic acid and sodium hydroxide as precipitation agents. Starting from zinc acetate and europium acetate, nanopowders were obtained by coprecipitation with oxalic acid. ZnO b...
Chapter
Full-text available
When choosing adequate materials for applications that require implantation in living organisms, knowing their properties is fundamental. Hence, for implants dedicated to bone tissue replacement, advanced mechanical properties and biocompatibility are key targets, while for blood vessel implants the key requirements are the surface properties and e...

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