Ioannis Androulakis

Ioannis Androulakis
Erasmus MC | Erasmus MC · Department of Radiotherapy

MSc in Medical Physics

About

13
Publications
4,046
Reads
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13
Citations
Citations since 2016
12 Research Items
13 Citations
20162017201820192020202120220246810
20162017201820192020202120220246810
20162017201820192020202120220246810
20162017201820192020202120220246810
Additional affiliations
January 2019 - present
Erasmus MC
Position
  • PhD
August 2017 - September 2018
Erasmus MC
Position
  • Intern
October 2016 - June 2017
University Hospital of Heraklion
Position
  • Researcher
Education
October 2015 - June 2017
September 2008 - September 2015

Publications

Publications (13)
Article
Full-text available
OBJECTIVE In High Dose Rate Brachytherapy for prostate cancer there is a need for a new way of increasing cancer cell kill in combination with a stable dose to the organs at risk. In this study, we propose a novel ThermoBrachy applicator that offers the unique ability to apply interstitial hyperthermia while simultaneously serving as an afterloadi...
Article
Full-text available
The combination of interstitial hyperthermia treatment (IHT) with high dose rate brachytherapy (HDR-BT) can improve clinical outcomes since it highly enhances the efficiency of cell kill, especially when applied simultaneously. Therefore, we have developed the ThermoBrachy applicators. To effectively apply optimal targeted IHT, treatment planning i...
Article
Full-text available
In high-dose-rate brachytherapy (HDR-BT) for prostate cancer treatment, interstitial hyperthermia (IHT) is applied to sensitize the tumor to the radiation (RT) dose, aiming at a more efficient treatment. Simultaneous application of HDR-BT and IHT is anticipated to provide maximum radiosensitization of the tumor. With this rationale, the ThermoBrach...
Article
Full-text available
The evaluation of the biological effects of therapeutic hyperthermia in oncology and the precise quantification of thermal dose, when heating is coupled with radiotherapy or chemotherapy, are active fields of research. The reliable measurement of hyperthermia effects on cells and tissues requires a strong control of the delivered power and of the i...
Article
Full-text available
Objective The addition of hyperthermia in the treatment of intact breast cancer with the aim to improve local response is currently in a research phase. First, optimal hyperthermia devices need to be developed, for which a diverse, anatomically and pathologically accurate set of patient models is necessary. Methods To investigate the effects of in...
Article
Background and Objective Magnetic hyperthermia is an oncological therapy that employs magnetic nanoparticles activated by alternating current (AC) magnetic fields with frequencies between 50 kHz and 1 MHz, to release heat in a diseased tissue and produce a local temperature increase of about 5 °C. To assess the treatment efficacy, in vivo tests on...
Preprint
The combination of interstitial hyperthermia treatment (IHT) with high dose rate brachytherapy (HDR-BT) for prostate cancer treatment and has the potential to improve clinical outcome, since it highly enhances the efficiency of cell kill, especially when applied simultaneously. Therefore, we have developed the ThermoBrachy applicators. To effective...
Preprint
Cardiac computed tomography (CT) is a valuable tool for functional mechanical heart valve (MHV) assessment. An important aspect of bileaflet MHV assessment is evaluation and measurement of leaflet opening and closing angles. Performed manually however, it is a laborious and time consuming task. In this paper, we propose an automated approach for bi...
Conference Paper
Introduction Computed tomography angiography (CTA) is a valuable tool for functional prosthetic heart valve (PHV) assessment. An important aspect of PHV assessment is evaluation of leaflet motion and measurement of leaflet opening and closing angles. Performed manually this is however a laborious and time consuming task. We developed a semiautomati...
Thesis
Full-text available
Objective: The purpose of this study was to investigate the effect of heart rate on the coronary artery calcium (CAC) score estimate provided by a modern 64-slice multi-slice CT system. Methods and Materials: Cylindrical calcified lesion phantoms of varying size and calcium concentration were constructed to mimic atheromatic plaques occurring in a...
Thesis
This thesis, after an extended analysis of the theory and the recent advances of medical image registration and fusion, investigates the output quality of a voxel based rigid registration algorithm that is being used in commercial radiotherapy treatment planning systems, when it is applied on monomodal intersubject CT images. This is being done by...

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Projects

Projects (3)
Project
The development of a complete system for enhanced HDR Brachytherapy dose with the use of interstitial hyperthermia.
Archived project
automation of PHV localization, visualization and quantification