Ingrid Farias

Ingrid Farias
Universidade Federal de São Paulo | UNIFESP · Center of Celular and Molecular Therapy


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Master's student in the Microbiology, Immunology and Parasitology Program at the Federal University of São Paulo (UNIFESP) and the main interest of my project is to investigate the role of inflammasomes in ZIKV infection in glial cells of the central nervous system.


Publications (2)
Full-text available
The content of tumor-derived extracellular vesicles (EVs) can regulate the tumor microenvironment and functionally acts in favor of cancer aggressiveness. To better elucidate the role of EVs in the interplay between immune system and tumor microenvironment, the purpose of this study was to analyze the effect of head and neck squamous cells carcinom...
Astrocytes and microglia are the most abundant glial cells. They are responsible for physiological support and homeostasis maintenance in the central nervous system (CNS). The increasing evidences of their involvement in the control of infectious diseases justify the emerging interest in the improvement of methodologies to isolate primary astrocyte...


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Project (1)
Inflammasomes are multiprotein capsules present in the cell cytosol capable of activating a caspase-1 protease in the cleavage of IL-1β / IL-18 proinflammatory cytokines capable of also forming a G-pore-forming protein D, causing an inflammatory cell death called pyroptose . Inflamasome-mediated viruses may be as beneficial both for viral control and for exacerbation of infection-related pathology, the central effect of which is to investigate the causes of inflammation in the central nervous system's glial cells by Zika virus (ZIKV), an arbovirus associated with neurological disorders.