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Introduction
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Publications
Publications (15)
To coordinate the redundant degrees of freedom (DOF) in the action system, synergies are often proposed. Synergies organize DOF in temporary task-specific units emerging from interactions among task, organism, and environmental constraints. We examined whether task constraints affect synergies, end-effector kinematics, or both. To this end, we comp...
Background
Functional movement disorders (FMDs) pose a diagnostic challenge for clinicians. Over the years several associated features have shown to be suggestive for FMDs. We examined which features mentioned in the literature are discriminative between functional and non‐functional movement disorders (non‐FMDs) in a large cohort. In addition, we...
Background
Myoclonus is characterized by involuntary, shock‐like movements, of which cortical (CM) and non‐cortical myoclonus (NCM) are most common. Electrophysiology can help differentiate between these subtypes; however, the diagnostic value of several features is largely unknown.
Objective
This study aims to determine the diagnostic value of th...
Background
Digital technologies have become more important in the health care sector in the past decades. This transition from conventional to digital health care has been accelerated by the impact of the COVID-19 pandemic, which poses the risk of creating a “digital divide,” inadvertently placing those who are older, economically disadvantaged, an...
This study investigates the strategies used by student groups when dealing with a design issue.
Ten groups of six students participated (n=60) in a hackathon that covered one day. Students were given the following assignment: Develop a (level of a) serious game or simulation tool to prepare a future health innovator for a (typical) design challeng...
BACKGROUND
Digital technologies have become more important in the health care sector in the past decades. This transition from conventional to digital health care has been accelerated by the impact of the COVID-19 pandemic, which poses the risk of creating a “digital divide,” inadvertently placing those who are older, economically disadvantaged, an...
This chapter provides a general overview of the terms and concepts in machine learning and is written for neurology clinicians who are new in this area. We use the classification of fruit and vegetables as an illustrative example but also explain concepts in the context of movement disorders. Our aim is to give a basic understanding of machine lear...
Introduction:
Inborn errors of metabolism are genetic disorders that need to be recognized as early as possible because treatment may be available. In late-onset forms, core symptoms are movement disorders, psychiatric symptoms, and cognitive impairment. Eye movement disorders are considered to be frequent too, although specific knowledge is lacki...
Introduction:
Our aim is to develop a novel approach to hyperkinetic movement disorder classification, that combines clinical information, electromyography, accelerometry and video in a computer-aided classification tool. We see this as the next step towards rapid and accurate phenotype classification, the cornerstone of both the diagnostic and tr...
An essential step in uncontrolled manifold analysis is creating a linear model that relates changes in elemental variables to changes in performance variables. Such linear models are usually created by means of an analytical method. However, a multiple regression analysis is also suggested. Whereas the analytical method includes only averages of jo...
Goal‐directed actions become truly functional and skilled when they are consistent yet flexible. In manual pointing, end‐effector consistency is characterized by the end position of the index fingertip, whereas flexibility in movement execution is captured by the use of abundant arm‐joint configurations not affecting the index finger end position....
Flexibility in motor actions can be defined as variability in the use of degrees of freedom (e.g., joint angles in the arm) over repetitions while keeping performance (e.g., fingertip position) stabilized. We examined whether flexibility can be increased through enlarging the joint angle range during practice in a manual obstacle-avoidance target-p...
Kinematic and UCM measures.
The third tab gives the explanation of the abbreviations.
(XLSX)
Joint angle variance per joint for each Instant and for the pretest and posttest.
(DOCX)
In point-to-point reaching movements, the trajectory of the fingertip along the horizontal plane is not completely straight but slightly curved sideward. The current paper examines whether this horizontal curvature is related to the height to which the finger is lifted. Previous research suggested that the height to which the hand is lifted might b...