Inga Mewis

Inga Mewis
Humboldt-Universität zu Berlin | HU Berlin · Faculty of Life Sciences, Albrecht Daniel Thaer-Institute of Agricultural and Horticultural Sciences

Dr.

About

158
Publications
32,696
Reads
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4,032
Citations
Citations since 2017
17 Research Items
2075 Citations
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20172018201920202021202220230100200300
20172018201920202021202220230100200300
20172018201920202021202220230100200300
Additional affiliations
November 2013 - March 2017
Julius Kühn-Institut
Position
  • Research Associate
May 2009 - April 2014
Leibniz-Institute of Vegetable and Ornamental Crops
Position
  • Phytochemistry Group

Publications

Publications (158)
Article
Full-text available
With the worldwide industrialization of black soldier fly (BSF) production, it is necessary to better understand how the rearing scale and larvae density influence the performance of larvae and the quality of the final product. In this study, a factorial experiment was conducted to test the effect of rearing scale and density on the growth and comp...
Article
Full-text available
Herbal preparations of willow bark (Salix cortex) are available in many countries as non-prescription medicines for pain and inflammation, and also as dietary supplements. Currently only little information on toxicity and drug interaction potential of the extracts is available. This study now evaluated the effects of two Salix cortex extracts on hu...
Article
Full-text available
Salix cortex-containing medicine is used against pain conditions, fever, headaches, and inflammation, which are partly mediated via arachidonic acid-derived prostaglandins (PGs). We used an activity-guided fractionation strategy, followed by structure elucidation experiments using LC-MS/MS, CD-spectroscopy, and 1D/2D NMR techniques, to identify the...
Article
Full-text available
The usefulness of anti-inflammatory drugs as an adjunct therapy to improve outcomes in COVID-19 patients is intensely discussed in this paper. Willow bark (Salix cortex) has been used for centuries to relieve pain, inflammation, and fever. Its main active ingredient, salicin, is metabolized in the human body into salicylic acid, the precursor of th...
Article
Full-text available
Willow bark is traditionally used for pharmaceutical purposes. Evaluation is so far based on the salicylate content, however, health promoting effects of extracts might be attributed to the interaction of those salicylates with other compounds, which support and complement their action. So far, only S. purpurea , S. daphnoides , and S. fragilis are...
Article
Full-text available
The current study has determined the effect of red and blue lights on the enhancement of growth, antioxidant property, phytochemical contents, and expression of proteins in Scrophularia kakudensis. In vitro-grown shoot tip explants of S. kakudensis were cultured on the plant growth regulator-free Murashige and Skoog (MS) medium and cultured under t...
Article
Full-text available
Four silica-based acaricides were examined in laboratory tests for their effectiveness against poultry red mite, Dermanyssus gallinae. All acaricides resulted in 100% mite mortality. Two groups of active ingredients could be differentiated. The products Silicosec® and Ewazid®, based on naturally occurring diatomaceous earth (DE), killed 100% of adu...
Article
Tropospheric ozone is an important ambient atmospheric pollutant component in urban areas. Determining plant reactions to ozone in plant growth and biochemical quality contents plays an important role in understanding plant metabolism. This study aimed to provide an understanding of the effect of ozone on early vegetative growth stage Pak-Choi (Bra...
Article
Determining plant reactions to atmospheric pollutants is important in predicting and planning for new horticultural production management programs and challenges in the future. A high level of ozone in the troposphere is considered the most phototoxic air pollutant, and has strong oxidative potential. This study aimed to provide understanding on th...
Article
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We previously showed that purified 1-methoxy-3-indolylmethyl (1-MIM) glucosinolate, a secondary plant metabolite in Brassica species, is mutagenic in various in vitro systems and forms DNA and protein adducts in mouse models. In the present study, we administered 1-MIM glucosinolate in a natural matrix to mice, by feeding a diet containing pak choi...
Article
Full-text available
Main conclusion This study demonstrates that the application of the PGPB strain, Kosakonia radicincitans enhances a plant’s resistance against phloem-feeding and chewing insects in Arabidopsis thaliana. The plant growth-promoting bacterial strain K. radicincitans DSM 16656 applied to A. thaliana reduced the number of phloem-feeding insects of both...
Article
Full-text available
Glucosinolates (GS) are secondary plant metabolites comprising different subgroups with opposing effects on human health. Hairy root cultures (HRC) are potent biotechnological tools allowing the biosynthesis of special substances under defined conditions. HRC of Eruca sativa, a brassicaceaous plant, were used to test different strategies to enhance...
Conference Paper
Full-text available
An increasing amount of greenhouse vegetables is produced using hydroponic systems. The used mineral fertilizers are often generated in energy consuming processes (esp. nitrate in Haber-Bosch) or gained from finite resources (esp. phosphate rock). Recovering the respective nutrients from waste streams is a promising option to make crop production m...
Article
Scope: Nasturtium plants contain the glucosinolate glucotropaeolin and its corresponding breakdown product benzyl isothiocyanate (BITC), the latter being intensively studied with regard to cancer chemoprevention and anti-inflammatory properties. In addition, recent research has shown that isothiocyanates are able to activate the release of several...
Chapter
Epidemiological studies have revealed an inverse association between a high consumption of vegetables and a lower risk of both cancer and cardiovascular diseases. This protective effect is mostly due to secondary plant metabolites present in plant tissues. In this context, it has become increasingly clear during the last decade that UV-B radiation...
Article
Leaves of Moringa oleifera are used by tribes as biological cancer medicine. Scientific investigations with M. oleifera conducted so far have almost exclusively used total plant extracts. Studies on the activity of single compounds are missing. Therefore, the biological effects of the two main aromatic multi-glycosylated glucosinolates of M. oleife...
Article
Full-text available
Nasturtium (Tropaeolum majus L.) contains high concentrations of benzylglcosinolate. We found that a hydrolysis product of benzyl glucosinolate—the benzyl isothiocyanate (BITC)—modulates the intracellular localization of the transcription factor Forkhead box O 1 (FOXO1). FoxO transcription factors can antagonize insulin effects and trigger a variet...
Article
Full-text available
The spider mite Tetranychus urticae Koch and the aphid Myzus persicae (Sulzer) both infest a number of economically significant crops, including tomato (Solanum lycopersicum). Although used for decades to control pests, the impact of green lacewing larvae Chrysoperla carnea (Stephens) on plant biochemistry was not investigated. Here, we used profil...
Data
C. carnea larva on a leaf of tomato S. lycopersicum “Ailsa Craig.”.
Data
Mean (±SD) peak area of the most abundant volatiles emitted by tomato S. lycopersicum “Ailsa Craig” leaves after four weeks of treatment with spider mites T. urticae and/or aphids M. persicae in the presence/absence of predaceous C. carnea larvae.
Data
Targeted-analysis of free amino acids. (A) Mean (±SD) concentration of free amino acids in the leaves of tomato S. lycopersicum “Ailsa Craig” after 4 weeks of treatment with spider mites T. urticae and/or aphids M. persicae in the presence/absence of predaceous C. carnea larvae (ng/g dry weight). (B) Mean (±SD) concentration of free amino acids in...
Data
Tentative identification (±10 ppm) of tomato metabolites (S. lycopersicum “Ailsa Craig”) significantly impacted after four weeks of treatment with spider mites T. urticae and/or aphids M. persicae in the presence/absence of predaceous C. carnea larvae (p ≤ 0.01, one-way ANOVA, fold change ≥ 2, N = 7).
Article
Full-text available
Aggregations of the striped flea beetle Phyllotreta striolata on their crucifer host plants are mediated by volatiles emitted from feeding males. The male-specific sesquiterpene, (6R,7S)-himachala-9,11-diene (compound A), was shown previously to be physiologically and behaviorally active, but compound A was attractive only when combined with unnatu...
Chapter
Full-text available
Each plant has its own native epiphytic population which is distinct from that of other plants in the vicinity. Their high tolerance to physical and chemical stresses renders them unique from other bacterial population. Phyllosphere being considered most nutrient scarce terrestrial habitat provoked us to understand the underlying mechanisms of sele...
Article
Full-text available
Spider mites, Tetranychus urticae Koch (Acari: Tetranychidae) and aphids, Myzus persicae (Sulzer) (Pterygota: Aphididae) share many host-plants, similar abiotic conditions and are world-wide distributed therefore, they often occur simultaneously in crops. However, the effects of interspecific interactions on the biology of these pests were poorly i...
Article
Full-text available
The legume pod borer, Maruca vitrata, is a pantropical pest on leguminous crops. (E,E)-10,12-Hexadecadienal, (E,E)-10,12-hexadecadienol, and (E)-10-hexadecenal were described previously as sex pheromone components for this nocturnal moth. A blend of these components in a ratio of 100:5:5 attracted males in field trapping experiments in Benin, but n...
Article
Full-text available
Link to full-text: http://pubs.acs.org/articlesonrequest/AOR-VQdfStJcVWnPy7ZASYKY Tomato is susceptible to pest infestations by both spider mites and aphids. The effects of each individual pest on plants are known, whereas multiple-pest infestations have received little interest. We studied the effects of single- versus multiplepest infestation by...
Article
Urban horticulture, the intensive production and cultivation of plants in dense populated areas exists since the first cities have been established by mankind. The earliest reports date back 4000 years, but the role urban horticulture has played has changed since in time and space. During periods of hunger urban horticulture is and has been product...
Article
Background and aims: Glucotropaeolin is the major glucosinolate in Indian cress (nasturtium; Tropaeolum majus L.). Its highly reactive breakdown product, benzyl isothiocyanate (BITC), demonstrated antibacterial, antitumorigenic, and anti-inflammatory properties in vitro and in rodent studies. The aim of this study was to investigate acute effects o...
Article
Moringa oleifera is widely cultivated in plantations in the tropics and subtropics. Previous cultivation studies with M. oleifera focused primarily only on leaf yield. In the present study the contents of potentially health-promoting secondary metabolites, (glucosinolates, phenolic acids, and flavonoids) were also investigated. Six different ecotyp...
Article
Glucosinolates are the characteristic secondary metabolites of plants in the order Brassicales. To date the common DIN extraction ‘desulfo glucosinolates’ method remains the common procedure for determination and quantification of glucosinolates. However, the desulfation step in the extraction of glucosinolates from Moringa oleifera leaves resulted...
Article
Poultry red mite infestation still is an unsolved problem in poultry farms. Legal regulations, residue risks, and resistances limit chemical control of mites. Alternatives to chemical acaricides for control of poultry red mite are silica-based products, which have as a main constituent silicon dioxide. The acaricidal effect is attributed to sorptiv...
Article
Two cytochrome P450 proteins, CYP79F1 and CYP79F2, are involved in the biosynthesis of aliphatic glucosinolates (GSs) in brassicaceous species. In order to increase aliphatic GS levels in Arabidopsis thaliana hairy root cultures (HRCs) with the aim of biomanufacturing GSs, CYP79F1 and CYP79F2 from either Arabidopsis thaliana or Brassica rapa were f...
Article
Full-text available
Significance Associations of plants and herbivores are regarded as the result of coevolution, which has produced an astonishing diversity of plant defenses and corresponding insect counteradaptations. We focus on the leaf beetle Phyllotreta striolata , which is adapted to the glucosinolate-myrosinase system present in its cruciferous host plants. W...
Article
High consumption of Brassica vegetables is considered to prevent especially colon carcinogenesis. The content and pattern of glucosinolates (GSLs) can highly vary among different Brassica vegetables and may, thus, affect the outcome of Brassica intervention studies. Therefore, we aimed to feed mice with diets containing plant materials of the Brass...
Article
Full-text available
Moringa is a mycorrhizal crop cultivated in the tropics and subtropics and appreciated for its nutritive and health-promoting value. As well as improving plant mineral nutrition, arbuscular mycorrhizal fungi (AMF) can affect plant synthesis of compounds bioactive against chronic diseases in humans. Rhizophagus intraradices and Funneliformis mosseae...
Article
Full-text available
In Colombia, the cape gooseberry is grown in salt-affected areas. The effect of increasing sodium chloride (0, 60 and 120 mM NaCl) stress was investigated on the growth, proline content and total antioxidant activity (TAA) in leaves of cape gooseberry plants kept in 2 L pots and grown under greenhouse conditions. Plant leaves were analyzed 45, 55,...
Article
Full-text available
Hairy root cultures transformed with Agrobacterium rhizogenes or undifferentiated callus cultures are used for production of plant secondary metabolites. Glucosinolates (GS) are a group of secondary metabolites that produce a variety of bioactive compounds upon hydrolysis. Several studies report the successful production of high concentrations of s...
Article
1-Methoxy-3-indolylmethyl (1-MIM) glucosinolate, a secondary metabolite of Brassicales species, and its breakdown product 1-MIM alcohol are mutagenic in cells in culture after activation by plant β-thioglucosidase and human sulphotransferase, respectively. In the present study, we administered these compounds orally to mice to study time course, do...
Article
Full-text available
Die stark zunehmende Luftverschmutzung urbaner Räume durch Feinstaub stellt ein Problem für die menschliche Gesundheit dar. Pflanzen besitzen die Eigenschaft, Luftpartikel an ihre Oberfläche zu binden und somit aus dem Luftraum zu entfernen. Dachbegrünungen können dazu beitragen, die Feinstaubbelastungen in der Stadt zu reduzieren. Um Dachbegrünung...
Article
A liquid chromatography–tandem mass spectrometry (LC-MS/MS) method was developed and validated to determine the concentration of benzyl isothiocyanate (BITC) metabolites in human plasma and urine. In this study, the following BITC metabolites have been considered: BITC–glutathione, BITC–cysteinylglycine, BITC–cysteine, and BITC–N-acetyl-l-cysteine....
Article
To obtain healthy plant material from Moringa oleifera regardless of season, weather, and degree of infestation, a procedure to establish an in vitro culture of M. oleifera from nodes using 0.2 % mercury chloride was developed. It was not possible to create an in vitro culture of M. oleifera from seeds. Nodes were cultivated on MS medium with diffe...
Article
Full-text available
Modern research on the insecticidal effects of inert dusts as a stored-grain protectant and for plant protection purposes began in the 1920's. The main advantage of inert dusts is their low environmental thread. One group of inert dusts used for pest control is amorphous silica. Amorphous silica has been tested as a whole and is according to the In...
Article
Die insektizide Wirkung inerter Stäube ist bereits seit Jahrhunderten bekannt, jedoch wurde der genaue Wirkmechanismus vieler Stäube erst in den letzten Jahrzehnten untersucht. Die insektizide Eigenschaft von Silikatstäuben wird auf die Physisorption von Cuticularlipiden und damit einhergehende Zerstörung der Wachsschichtder Epicuticula sowie folge...
Article
Full-text available
Although some study have established hairy root cultures from brassicaceous plants with glucosinolates (GS) as characteristic secondary metabolite, studies are missing which compare hairy roots with the corresponding mother plants. Therefore, two different plant species-Sinapis alba and Brassica rapa subsp. rapa pygmeae teltoviensis-were transforme...
Article
Full-text available
Plant growth-promoting bacteria (PGPB) affect plant cellular processes in various ways. The endophytic bacterial strain Enterobacter radicincitans DSM 16656 has been shown to improve plant growth and yield in various agricultural and vegetable crops. Besides its ability to fix atmospheric nitrogen, produce phytohormones, and solubilize phosphate co...
Article
Full-text available
Little is known about how drought stress influences plant secondary metabolite accumulation and how this affects plant defense against different aphids. We therefore cultivated Arabidopsis thaliana (L.) plants under well-watered, drought, and water-logged conditions. Two aphid species were selected for this study: the generalist Myzus persicae (Sul...
Data
Full-text available
Primers list of genes associated with glucosinolate, camalexin biosynthesis or signaling pathways. (PDF)
Data
Full-text available
UV-spectra of desulfo GS from Arabidopsis (Col-0). (PDF)
Article
The larvae of the legume pod borer, Maruca vitrata (Lepidoptera: Pyralidae), cause severe damage on economically important legume crops in the tropics. The female moth produces volatile components to attract males for mating. The so-called sex pheromones are species-specific multi-component blends and are used as lures in crop protection for pest m...
Article
Full-text available
Parthenium is an exotic invasive weed that originated in tropical America, but now occurs widely in India, Australia, and Africa. In Ethiopia, it is growing in different ecological zones, covering altitudes between 900 and 2500 m above sea level. We analyzed secondary metabolites in Parthenium grown in different regions of Ethiopia. Sesquiterpene l...
Article
In Brassica vegetables, heating processes lead to thermally induced degradation of glucosinolates (GSLs), resulting in the formation of nitriles and isothiocyanates (ITCs). To date, the mechanism is not yet satisfyingly elucidated. Thermally induced degradation of the model GSL sinigrin was studied in dry as well as aqueous medium at different pH v...
Chapter
Plants encounter multiple stresses in the field and drought is a major environmental stress that can alter their chemical composition, which influence their tolerance to insect herbivory. Brassica oleracea var. italica Plenck (broccoli) was grown under well-watered and drought conditions and artificially infested with two aphid species, the special...
Article
Glucosinolates, present in Brassica vegetables, are thought to contribute to human health prevention because of their enzymatically induced breakdown products, primarily isothiocyanates (ITCs). ITCs are reactive substances that readily react with nucleophilic (food) compounds. The reactivity of allyl-ITC and 4-(methylsulfinyl)butyl-ITC (sulforaphan...
Article
Full-text available
Only a few environmental factors have such a pronounced effect on plant growth and development as ultraviolet light (UV). Concerns have arisen due to increased UV-B radiation reaching the Earth’s surface as a result of stratospheric ozone depletion. Ecologically relevant low to moderate UV-B doses (0.3–1 kJ m–2 d–1) were applied to sprouts of the i...
Article
Full-text available
Epidemiological studies have revealed an inverse association between the consumption of fruit, vegetables, a