Indu SHEKHAR Thakur

Indu SHEKHAR Thakur
Jawaharlal Nehru University | JNU · School of Environmental Sciences

Ph.D

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283
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Publications

Publications (283)
Article
Full-text available
The increase in demand of fossil fuel uses for developmental activity and manufacturing of goods have resulted a huge emission of global warming gases (GWGs) in the atmosphere. Among all GWGs, CO2 is the major contributor that inevitably causes global warming and climate change. Mitigation strategies like biological CO2 capture through sequestratio...
Article
Full-text available
The present research work highlights the biosurfactant application toward enhanced pyrene degradation by Pseudomonas sp. Lipopeptide-type biosurfactant was produced from Free Air CO2 Enriched (FACE) soil bacterium Bacillus sp. SS105. The different concentrations of biosurfactant at different time intervals were optimized for maximum pyrene degradat...
Article
In the current study, the isolated Methylobacterium sp. ISTM1 simultaneously produced both extracellular polymeric substances (EPS) and polyhydroxyalkanoates (PHA) in a single-step process. The yield of biopolymers (EPS and PHA) was enhanced by optimizing the process parameters of EPS and PHA production. Methylobacterium sp. ISTM1 was able to produ...
Article
Most of the discarded waste material paves their way to the utmost common dumping grounds, Landfills. Despite their widespread use, the landfill microbiomes are still not well characterized. Metagenomics approach provides insight into the identification of operational parameters influencing the microbiome composition and their biodegradation compet...
Article
Full-text available
Among azo dyes, methyl red dye is mutagenic and its persistence causes serious impacts on the environment and human health. The current study is the first report of methyl red dye degradation by an actinobacterium, Zhihengliuella sp. ISTPL4. Strain showed 98.87% of 500 mg/L methyl red dye degradation within 12 h. Optimization of the efficient decol...
Article
The present study involves physico-chemical profiling and toxicity assessment of wastewater and sludge samples collected from subsequent treatment stages of extended aeration activated sludge (EAAS) process based municipal wastewater treatment plant (WWTP). Wastewater samples were collected from inlet, aeration tank, final settling tank and outlet,...
Chapter
In this 21st century, current greenhouse gas (GHG) concentrations and projected emissions are likely to increase global temperature by 1.2–4.8°C escalating climate change. Moreover, population explosion with declining natural resources has resulted in an upsurge in food demand burdening the agriculture sector to increase crop production. This along...
Chapter
Climate change has been associated with a range of health complications in humans and other organisms; however, how climate-related anthropogenic environmental changes produce health deficits at the organismal level remains to be fully understood. Organism adaptation to changes in the environment has been generally corelated with genomic alteration...
Chapter
Increasing environmental concentrations of methane have a huge impact on the Earth's climate, owing to its high global warming potential. Thus, its biological conversion by methane oxidizing bacteria, i.e., methanotrophs offer an environmentally friendly and cost-efficient solution to combat climate change. Advances in the omics-based study of meth...
Chapter
The dual crisis of climate change and fossil fuel depletion has led to the search for a clean, environmentally sustainable, and globally available fuel which is also able to meet the surging energy demand. Hydrogen is one such element that could fulfill all these criteria. However, the major source of hydrogen generated today globally (approximatel...
Chapter
Greenhouse gases are the major cause of global warming. Carbon dioxide, a major greenhouse gas, is released into the atmosphere because of fossil fuel burning and deforestation. Researchers are trying to control escalating level of CO2 by a global approach of carbon capture, storage, and utilization (CCSU) methodology. Bioelectrochemical system (BE...
Chapter
The dumping of unsegregated waste in landfills which contains a very high amount of organic fraction has become a factory for the production of greenhouse gases (GHGs) such as methane and carbon dioxide. Landfill sites contribute around 11% of the global methane emissions. The release of GHGs in the environment causes great damage to the ecosystem....
Chapter
Environmental DNA (eDNA) is an excellent biological resource which has not been optimally explored to monitor the climate change impact. The climate change induces both abiotic and biotic environmental stressors. Investigation of the impact of biotic and abiotic environmental stressors at the organismal levels to decipher their interactions influen...
Chapter
Biomaterials are materials that have been engineered so that they can interact with the components of living systems. They are engineered for a medical purpose and are also used in therapeutic purposes or the diagnostic purposes. Generally, the most common biomaterials are metals, polymers, glass, or ceramics. In this chapter, microbiological impor...
Article
The presence of steroid hormones in the marine bodies, in the recent past, has led to the eruption of endocrine disrupting molecules which have detrimental effects on aquatic life. However, the resilience and robustness of diatoms to adsorb and grow under multitude of nutrient stress allows them to utilize plethora of such compounds. Hence, in this...
Article
In the present study, a bacterial strain, Parapedobacter sp. ISTM3, isolated from the cave was screened for PHA (polyhydroxyalkanoate) production using molasses (agro-industrial waste) as carbon substrate. Additionally, the production of PHA was enhanced by using different carbon substrates, incubation time, and concentration of carbon substrate. P...
Chapter
In the present world, climate change and global warming are the foremost problems in front of the human race. These problems have arisen due to the increase in Greenhouse gases (GHGs) concentration in the atmosphere. Most of the factors responsible for GHGs emissions are anthropogenic such as fossil fuel combustion, biomass burning, etc. Nature has...
Chapter
Climate change has severe effects on soil microorganisms that regulate the biochemical cycle of nutrients and other components necessary for plants growth. Understanding the nutritional viability and microbial interaction under climate change is vital for future research. Several environmental factors like elevated CO2, temperature, drought and sal...
Article
Agroforestry, an integration of farming system with woody perennials leads to the generation of potential agroforestry residues. The conventional treatment of agroforestry waste includes landfilling, thermal management, and decomposition which is accompanied with their own share of disadvantages. The ample amount of residues and products needs effe...
Article
Long-term research on biofuel production from lignocellulose did not progress much due to strong inter-unit linkages in lignin structure. Lignin contains β-O-4 linkage as a major bond (50–60%) between aromatic compounds to form a complex 3D-structure. The present study aims for the characterization of a novel strain Burkholderia sp. ISTR5 (R5) for...
Article
The present study was aimed to recover and characterize the polyhydroxyalkanoates (PHA) from secondary sludge biomass of sewage treatment plant (STP) extracted by organic solvent under optimized conditions. The maximum recovery yield and purity of PHA were 8.3% and 96%, respectively under optimized conditions of incubation time 72 h, reaction tempe...
Article
The bioconversion of 15 lignin-derived compounds (LDCs) into polyhydroxyalkanoate (PHA) was studied in the present study. PHA accumulating strain Burkholderia sp. ISTR5 was employed for the bioconversion of LDCs. Burkholderia sp. ISTR5 (R5) efficiently bioconverted LDCs into PHA. Due to low PHA yield on LDCs, the co-metabolism with agro-industrial...
Article
The current study demonstrates the enhanced production capability of strain Cupriavidus sp. ISTL7 for polyhydroxyalkanoates (PHA) using acetate and glucose (4.93 ± 0.4571 g L⁻¹) which was characterised analytically by GC-MS, FTIR and NMR analysis. Whole genome sequencing of strain ISTL7 unveiled an array of PHA metabolism genes which included phaA,...
Article
Filamentous cyanobacteria, Jacksonvillea sp. ISTCYN1 was isolated from agriculture field and cultured in BG-11 medium. This study, report the genome sequence of cyanobacteria Jacksonvillea that to the best of our knowledge is the first genome sequence of this genus. The 5.7 MB draft genome sequence of this cyanobacterium contains 5134 protein-codin...
Article
Syringyl monomeric units are the most common intermediates encountered during hardwood lignin degradation. In the present study, efficient utilization of syringaldehyde (SAld), syringic acid (SAc) by Burkholderia sp. ISTR5 (R5) has been shown. The proteogenomic analysis of Burkholderia sp. ISTR5 was done to understand the enzymes involved in the de...
Article
The present study discusses the genomic analysis of Bacillus sp. ISTL8 along with the production of EPS (Extracellular polymeric substances) using carbofuran, a toxic carbamate pesticide. Bacillus strain was isolated from landfill soil and evaluated for high growth rates and EPS production. One strain, renamed ISTL8 grew on a broad range of carbon...
Chapter
Full-text available
Fossil fuels are used for the generation of electrical power, as well as liquid fuels. There are a variety of renewable or low atmospheric pollution technologies that can generate electrical power, including solar, wind, hydroelectric, geothermal, and nuclear. However, renewable technologies to supplement or replace liquid fossil fuels are still in...
Chapter
Full-text available
Today, more than two-thirds of global energy supplies come from fossil fuels. However, dwindling reserve of fossil fuels, precarious global oil market, energy geopolitics, and associated environmental impacts due to fossil fuel burning have compelled almost all the nations of the world to search for clean and renewable alternatives for energy, fuel...
Chapter
The rising carbon dioxide (CO2) emission leading to global climate change is one of the greatest environmental challenges that the world faces today. The link between the anthropogenic CO2 emissions and its increased atmospheric concentration resulting in global average temperature rise and consequent sea level rise is well established. The CO2 mit...
Chapter
Polyphosphate (PolyP), formerly referred to as volutin granules, is ubiquitous with a diverse range of functions. PolyP is present in substantial amounts in prokaryotes and has extensively been researched for various enzymes and pathways involved in its synthesis and degradation. Both the formation and degradation of PolyP are enzyme-mediated proce...
Chapter
Industrialization, globalization and the human population explosion has resulted in the injection of toxic chemicals into the environment. One class of such chemicals that has shown its presence in most of the existing water bodies today is high atomic weight metals, collectively called heavy metals, like mercury, arsenic, lead, cadmium, and chromi...
Article
Polycyclic aromatic hydrocarbons (PAHs) such as pyrene are universal contaminants existing in the environment which have known cancer-causing and mutagenic characteristics. A psychrophilic bacterialstrainShewanellasp. ISTPL2 was isolated from the sediment sample collected from the Pangong lake, Jammu & Kashmir, India. In our previous study, the pyr...
Article
Treatment of wastewater for heavy metal removal is gaining much attention due to increase in pollution and insufficiency of water. Wastewater treatment processes is important in preventing heavy metal pollution of the receiving waters when discharged particularly from industrial effluents including electroplating industries. In this article, a nove...
Article
Landfill soil pollution is a huge cause of concern particularly in the developing countries like India where unsegregated wastes are disposed off in the open dumping sites, posing a high health risk to workers and rag pickers. This necessitates an efficient strategy for landfill soil reclamation. The present study evaluates the efficiency of a bios...
Article
The strain Burkholderia sp. ISTR5 (R5) was studied for polyhydroxyalkanoate (PHA) production on Kraft lignin (KL) and lignosulfonate (LS) as substrates. During the initial screening, the maximum PHA mass fraction in biomass produced on KL and LS was 23% and 18%, respectively, at 96 h. PHA production on KL was further optimized using the Box-Behnken...
Article
Full-text available
A psychrophilic and halophilic bacterial isolate, Shewanella sp. ISTPL2, procured from the pristine Pangong Lake, Ladakh, Jammu and Kashmir, India, was used for the production and characterization of the psychrophilic and alkalophilic α-amylase enzyme. The α-amylase is a critical enzyme that catalyses the hydrolysis of α-1,4-glycosidic bonds of sta...
Article
Phthalates are a group of emerging xenobiotic compounds commonly used as plasticizers. In recent times, there has been an increasing concern over the risk of phthalate exposure leading to adverse effects to human health and the environment. Therefore, it is necessary to not only understand the current status of phthalate pollution, their sources, e...
Article
Full-text available
Purpose: Nuclear respiratory factor 1 (NRF1) drives estrogen-dependent breast tumorigenesis. Herein we examined the impact of NRF1 activity on the aggressiveness and disparate molecular signature of breast cancer in Black, White, Asian, and Hispanic women. Methods: NRF1 activity by transcription factor target enrichment analysis and causal NRF1-...
Chapter
Full-text available
Fossil fuels are used for the generation of electrical power, as well as liquid fuels. There are a variety of renewable or low atmospheric pollution technologies that can generate electrical power, including solar, wind, hydroelectric, geothermal and nuclear. However, renewable technologies to supplement or replace liquid fossil fuels are still in...
Article
Full-text available
The present research investigates potential of microalgae isolated from sewage treatment plant to utilize sodium bicarbonate as carbon source for CO2 sequestration and biodiesel production. Eight algal isolates were isolated from waste water of sewage treatment plant, Amity University Haryana, India. The most potent algal isolates were identified a...
Article
In the current study, EPS producing strain Parapedobacter sp. ISTM3 was isolated from Mawsmai cave, Meghalaya, India. The strain ISTM3 showed enhanced EPS production (4.65 ±0.10 g L⁻¹) at optimized parameters, i.e., pH 8 and 3% molasses as a carbon source. The extracted EPS was structurally characterized by GC-MS, NMR, and FTIR analysis to investig...
Article
Full-text available
Most of environment-related diseases often result from multiple exposures of abiotic and/or biotic stressors across various life stages. The application of environmental DNA/RNA (eDNA/eRNA) to advance ecological understanding has been very successfully used. However, the eminent extension of eDNA/eRNA-based approaches to estimate human exposure to...
Article
The emission of greenhouse gases and global warming are the major environmental concerns that has affected the normal geochemical cycles and climate conditions on the earth. However, a controlled production, conversion and utilization of these gases for energy generation in day to day activities of human beings can solve the problem of climate chan...
Article
To mitigate the rising level of CO2, biological method of CO2 sequestration is one of the effective methods. Chemolithotrophic microbes are able to fix atmospheric CO2 and precipitated polymorphic minerals like calcite, vaterite and aragonite. Based on this, bioactive glass was synthesized by sol–gel process using polymorphic calcium carbonate mine...
Article
The aim of present study is to investigate the effect of different solvent on lipids extraction efficiency and biodiesel production under optimized process parameters from tannery sludge. Results have revealed that standard chloroform-methanol method has a higher lipid yield of 22.8% (w/v), corresponding to 98.5% (w/v) of lipid extraction efficienc...
Article
Excessive utilization of synthetic plastics has led to a major detrimental impact on the environment. Plastic pollution and accumulation in water bodies have particularly threatened the survival of marine life. Plastic pollution can be prevented by using biopolymers that are eco-friendly and can be naturally produced by certain living organisms. Th...
Chapter
Pulp and papermaking industry is a large consumer of fresh water and an important source of wastewater, generated during various stages of pulping and papermaking activities. The dark-brown-colored wastewater discharged from pulp and paper industry remains toxic and complex and retains lignin, lignin residues, resins, acids, chlorinated phenols, an...
Chapter
Full-text available
Environmental pollution has become a serious concern in the current world, and therefore, its mitigation is urgent to safeguard the environment and public health. Bioremediation is identified as an eco-friendly and sustainable remediation technology to minimize and control environmental pollution. It uses an array of microbes/plants to degrade and...
Article
Toxicity of AMD on rice seedlings lead to abnormal growth and development. Concentration (mg/L) of Mn (1671.17), Cu (84.55), Al (4530), Ti (834.97), Si (1974), S (1028) and Fe (12462) were detected in AMD. We developed an integrated bacteria-algal technology efficiently removing > 95% of toxic metals from AMD after 48 h of treatment following micro...
Article
Production of biodiesel from lipids of Serratia sp. ISTD04 by lipase of Pseudomonas sp. ISTPL3 immobilised on biocomposite materials to increase the enzyme stability and reusability was studied. Lipase extracted, partially purifiedand immobilized onto activated biochar, impregnated with calcite obtained from biomineralization-based conversion of CO...
Article
Bacterial, algal and bacto-algal cultures were set up with 50 ppm lindane to study the degradation and detoxification potency of the strains. Several intermediate metabolites like pentachlorocyclohexenes, tetrachlorocyclohexenes, trichlorocyclohexane, dichlorocyclohexane, aliphatic chlorinated compounds, phenols were detected using GC–MS. It was ob...
Article
Burkholderia, a bacterial genus comprising more than 120 species, is typically reported to inhabit soil and water environments. These Gram-negative bacteria harbor a variety of aromatic catabolic pathways and are thus potential organisms for bioremediation of sites contaminated with aromatic pollutants. However, there are still substantial gaps in...
Article
The current review explores the potential application of algal biomass for the production of biofuels and bio -based products. The variety of processes and pathways through which bio - valorization of algal biomass can be performed are described in this review. Various lipid extraction techniques from algal biomass along with transesterification re...
Article
The present study intends to evaluate the potential of co-digestion for utilizing Organic fraction of Municipal Solid Waste (OFMSW) and sewage sludge (SS) for enhanced biogas production. Metagenomic analysis was performed to identify the dominant bacteria, archaea and fungi, changes in their communities with time and their functional roles during t...
Chapter
The increasing load on the ecosystem with activities, such as deforestation, exploited land use, industrialization, and excess waste generation, leads to a global climate shift, which is one of the leading environmental issues of the world today. The basic biomolecules for the production of biofuel include fatty acids, alcohols, and alkanes. Biodie...
Article
To mitigate the rising level of CO 2 , biological method of CO 2 sequestration is one of the effective methods. Chemolithotrophic microbes are able to fix atmospheric CO 2 and precipitated polymorphic minerals like calcite, vaterite and aragonite. Based on this, bioactive glass was synthesized by sol-gel process using polymorphic calcium carbon-ate...
Chapter
This chapter highlights the importance of anaerobic digestion in pulp and paper mill waste (PPMW) treatment. Due to increasing environmental concerns and strict laws about the effluents from industries, it becomes imperative to use such a technology. PPMW contains a vast amount of organic contaminants that are recalcitrant. Postaerobic treatment, a...
Chapter
Water is a critical necessity and every life form is dependent on it. Wastewater is the liquid waste generated by anthropogenic activities (e.g., industrial, domestic, commercial, agriculture activities), which alters the physical, chemical, and biological quality of water. Hospital wastewater (HWW) contains different chemical and biological agents...
Chapter
Rapid industrialization, urbanization, and agricultural practices have led to the generation and release of various toxic organic and inorganic contaminants into the environment. These toxic contaminants can accumulate and persist for long periods of time and deteriorate the surrounding environment. Thus remediation of contaminated sites using micr...
Chapter
The industrial revolution and continuous greenhouse gases (GHGs) emission may lead to environmental changes to severe and irretrievable state. To mitigate this change not only reduction in GHGs emission but also atmospheric carbon dioxide capture and storage (CCS) will also be required. Bioenergy with CCS (BECCS) has been modeled to bring down the...
Article
Full-text available
Background: Lignin is the second most abundant natural polymer on earth. Industries using lignocellulosic biomass as feedstock generate a considerable amount of lignin as a byproduct with minimal usage. For a sustainable biorefinery, the lignin must be utilized in improved ways. Lignin is recalcitrant to degradation due to the complex and heteroge...
Article
This study deals with optimizing the pretreatment process for Leucaena leucocephala wood. Total 51 experiments were conducted. Three parameters were optimized i.e. catalyst concentration (1–3%), duration (120–300 min) and temperature (100–150 °C). Improvement in saccharification efficiency was evaluated using commercial cellulases. Single response,...
Article
Full-text available
In recent impetus of phycological research, microalgae have emerged as a potential candidate for various arena of application-driven research. Omics-based tactics are used for disentangling the regulation and network integration for biosynthesis/degradation of metabolic precursors, intermediates, end products, and identifying the networks that regu...
Article
Polycyclic aromatic hydrocarbons (PAHs) are universal environmental contaminants of great concern with regard to their potential exposure and deleterious effect on human health. The current study is the first report of phenanthrene degradation by a psychrotolerant (15 °C), halophilic (5% NaCl), and alkalophilic (pH 8) bacterial strain Zhihengliuell...
Article
Full-text available
In the present study, genomic analysis of a previously reported carbon dioxide (CO2) sequestering bacterium Serratia sp. ISTD04 was performed along with exopolysaccharide (EPS) production. Genomic analysis identified key and accessory enzymes responsible for CO2 sequestration. EPS synthesis genes were discovered in the genome and identified 8 putat...
Article
Full-text available
In the present study, genomic analysis of a previously reported carbon dioxide (CO2) sequestering bacterium Serratia sp. ISTD04 was performed along with exopolysaccharide (EPS) production. Genomic analysis identified key and accessory enzymes responsible for CO2 sequestration. EPS synthesis genes were discovered in the genome and identified 8 putat...
Article
The present study demonstrates EPS production by Cupriavidus sp. ISTL7 along with its capability to remediate a toxic carbamate pesticide, carbofuran. The strain ISTL7 efficiently degraded approximately 98% of carbofuran (400 ppm) within 96 h. GC–MS analysis showed catabolic metabolites of degradation which included carbofuran-7-phenol, methylamine...