inanç şamil sarıcı

Istanbul University · Department of General Surgery

Introduction and importance: Superior mesenteric artery syndrome (SMAS) is a rare but severe condition characterized by acute angulation of the aortomesenteric axis. It can result in compression and obstruction of the third part of the duodenum leading to life-threatening dilation and perforation of the proximal duodenum and stomach. Presentation...

Magnetic sphincter augmentation (MSA) was introduced in 2007 as an alternative surgical procedure for patients with gastroesophageal reflux disease (GERD). The majority of data since MSA’s introduction has focused on short and intermediate-term results, demonstrating safety and high efficacy in terms of reflux symptom control, freedom from proton p...

GERD after Peroral Endoscopic Myotomy: Assessment of Incidence and Predisposing Factors

Background: Studies show higher rates of dissatisfaction with antireflux surgery (ARS) outcomes in patients with chronic constipation. This suggests a relationship between colonic dysmotility and suboptimal surgical outcome. However, due to limitations in technology, there is no objective data available examining this relationship. The wireless mo...

Background: Peroral endoscopic myotomy (POEM) is an effective intervention for achalasia, but GERD is a major postoperative adverse event. This study aimed to characterize post-POEM GERD and identify preoperative or technical factors impacting development or severity of GERD. Study design: This is a retrospective review of patients who underwent...

Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and proces...

Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and proces...

Background: Acute appendicitis is the most frequently encountered non-obstetric disease requiring surgical intervention during pregnancy. Early diagnosis reduces maternal and fetal morbidity / mortality rates. Aim: This study aims to investigate hemogram parameters in the diagnosis of acute appendicitis in pregnant women. Material and methods:...

Background 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on...

p>Background: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications...

Background: Acute biliary pancreatitis is one of the most frequently encountered diseases among general surgeons in emergency surgical diseases. Differences in diagnosis and treatment management of these patients, varying from physician to physician, are common in clinical practice. We aimed to present these differences and discuss the results in...

Aim:The C-reactive protein (CRP)/albumin ratio is a new inflammation-based prognostic score that correlates with inflammation severity.Objective:The present study investigated the diagnostic value of the CRP/albumin ratio to distinguish between patients with simple and complicated acute appendicitis. This retrospective study was conducted at the Un...

Aim: The difficulty of detecting lesions smaller than 1 cm in the preoperative period is still a continuing problem in peritoneal carcinomatosis. Methods: The prospective data of 106 peritoneal carcinomatosis patients were included this study. Preoperative AFP, carcinoembryonic antigen, CA19.9, CA125, neutrophil/lymphocyte ratio, platelet/lymphocyt...

Purpose: Endoscopic retrograde cholangiopancreaticography (ERCP) is performed for diagnostic and therapeutic purposes in patients with pancreaticobiliary diseases. We investigated the role of simethicone and concomitant otilonium bromide during ERCP. Patients and methods: This prospective randomized study included 120 patients who underwent ERCP...

Introduction The mainstay of management for locally advanced rectal cancer is chemoradiotherapy followed by surgical resection. Following chemoradiotherapy, a complete response may be detected clinically and radiologically (cCR) prior to surgery or pathologically after surgery (pCR). We aim to report the overall complete pathological response (pCR)...

Introduction Some evidence suggests that primary anastomosis following left sided colorectal resection in the emergency setting may be safe in selected patients, and confer favourable outcomes to permanent enterostomy. The aim of this study was to compare the major postoperative complication rate in patients undergoing end stoma vs primary anastomo...

Abstract Introduction The optimal bowel preparation strategy to minimise the risk of anastomotic leak is yet to be determined. This study aimed to determine whether oral antibiotics combined with mechanical bowel preparation (MBP+Abx) was associated with a reduced risk of anastomotic leak when compared to mechanical bowel preparation alone (MBP) or...

Introduction: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been increasingly performed in many advanced centers of our country. Short-term quality of life (QoL) after the CRS with HIPEC was investigated in Turkish population. The purpose of our study was to investigate the QoL in patients operated for perit...

In patients with gastric cancer, surgical resection is the only treatment that can offer cure or increase long-term survival. With the accumulation of experience in laparoscopic radical gastrectomy and the progress in surgical instruments, laparoscopic surgery for gastric cancer has gained popularity despite initial concerns regarding safety and on...

Caecal volvulus is a result of rotation or torsion of mobilized caecum and ascending colon. It usually makes 1-3% of intestinal obstructions. Due to rarity and variable manifestations, clinical resolution may be prolonged and this may put patients into a risky status. In this study, we will discuss the clinical findings, diagnostic techniques and t...

Background: Platelets are considered an important source of prothrombotic agents associated with inflammation in cancer related diseases. We aimed to compare the diagnostic accuracy of the platelet distribution width (PDW) and CA19-9 in resectable pancreas cancer. Method: A total of 83 stage-1 and 2 pancreatic adenocarcinoma (PAC) patients, and 85...

Objectives: Gallbladder stones are the most frequently reported etiology of acute pancreatitis in pregnancy and are often diagnosed in the third trimester. This condition is associated with both mother and infant morbidity and mortality, and its treatment remains controversial. Methods: Relevant patient data between September 2010 and April 2017...

Introduction: The present study was designed to evaluate the effects of quercetin on hepatic ischemia-reperfusion (IR) injury in rats caused by Pringle maneuver.Methods: Overall, 24 5- to 6-month-old female Wistar Albino rats weighing 200-250 mg were included in the present study. In the sham group, laparotomy was performed 15 min after anesthesia...

BACKGROUND: The present study was conducted to investigate efficacy of N-Acetylcycteine (NAC) in preventing intra-Abdominal adhesions performed experimentally in rats. METHODS: Twenty male rats of Wistar - Albino species (250-350 gr) were divided into two groups for the study. Caecum and peritoneal surface in both groups were abrased with using dry...

Purpose: To compare platelet rich plasma (PRP) and fibrin glue about the effect of anastomotic healing. Methods: Thirty six Wistar-Albino male rats diveded into 3 groups according to control(Group1), PRP (Group 2) and fibrin glue(Tisseel VH) (Group 3). The colon was transected with scissor and subsequently an end to end anastomosis was performed...

Introduction: The current literature and guidelines recommend that determination of peritoneal violation is done first in cases of anterior abdominal stab wounds. The primary endpoint of this study was to determine the reliability of computed tomographic (CT) tractography to assess peritoneal violation in anterior abdominal stab wounds. The second...

Background: The clinical approach to back/flank wounds has evolved over the years. The aim of this study was to discuss the potential of computed tomography tractography in patients with a stab wound to the back or flank. Methods: A total of 25 stable patients with stab wounds confined to the back/flank region were enrolled in this retrospective...

BACKGROUND: Curcumin is the main component of curry spices known as turmeric. Turmeric comes from the Zingiberaceae plant family and it is a traditional Chinese herb used for inflammatory conditions. It has gained popularity over the last decades and became the subject of scientific researches because of its anti-inflammatory and anti-oxidant activ...

Purpose: To evaluate the efficacy of nivolumab and comparison with dacarbazine (DTIC) on peritoneal carcinomatosis of malignant melanoma in mouse model. Methods: Mouse skin melanoma cells was injected under the capsule of the peritoneal surface in the left side of the abdomen. On postoperative day ten, mouses randomised into three groups. Group 1:...

Aim:Although the anal benign disorders cover the etiology of intermittent hematochezia, neoplastic polyps and colorectal carcinomas may also cause this situation. The necessity of performing rectosigmoidoscopy or colonoscopy is controversial. The aim of the study was to present colonoscopy findings in young adult patients with intermittent hematoch...

Introduction: The present study was designed to evaluate the effects of quercetin on hepatic ischemia-reperfusion (IR) injury in rats caused by Pringle maneuver. Methods: Overall, 24 5- to 6-month-old female Wistar Albino rats weighing 200-250 mg were included in the present study. In the sham group, laparotomy was performed 15 min after anesthesi...

Background and study aims: Gallbladder polyps (GBPs) are found in 5-7% of the adult population. However, it is very important to differentiate between benign and malignant polyps to establish an appropriate treatment. The present study aimed to determine the relevance of the 10-mm size criterion and attempted to determine the cut-off diameter of T...

Raoultella planticola is an aquatic and soil organism that does not notoriously cause invasive infections in humans. Infections in the literature are limited only in case reports. We present a very rare case of R. planticola cholecystitis. A 71-year-old female patient with abdominal pain was diagnosed with acute cholecystitis. Patient received intr...

Objective: Rare disease Background: Toothpick ingestion is implicated in bowel injuries that may cause violent complications, mimicking diseases causing acute abdomen. Case Report: A 18-year-old man was admitted with a 3-day history of a swallowed wooden toothpick. The patient had tenderness in the left flank area. Computed tomography indicated too...

We report a case of 59-year-old woman with a painful left breast mass, compatible with types II-III hydatid cyst. Lesion was evaluated with mammography, ultrasound, computed tomography, and magnetic resonance imaging modalities. Magnetic resonance imaging had important diagnostic role with demonstrating characteristic features of the lesion and had...

Introduction Transmesenteric internal hernia is defined as the herniation of the small intestine from a mesenteric defect in the abdominal cavity, and abdominal cocoon syndrome is the partial or entire encapsulation of the small bowel like the shape of an accordion, by a fibrocollagenous membrane. Presentation of case A 32-year old male patient ap...

Purpose: The purpose of this study was to analyze retrospectively the risk factors for incisional hernia (IH) in a group of gynecological cancer patients operated with abdominal midline incisions. Methods: We retrieved retrospectively data of gynecological cancer patients with midline incisions from the clinical database of Kanuni Sultan Suleyman T...

Introduction: Pancreatic cancer (PAC) is the fourth leading cause of cancer death in man and women. The aim of this study was to investigate the prognostic significance of three systemic inflammation-based factors, preoperative neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and mean platelet volume (MPV) in patients undergoing P...

Objective: To investigate leukocyte count, neutrophil percentage, Neutrophil-Lymphocyte Ratio (NLR), Platelet-Lymphocyte ratio (PLR), mean platelet volume (MPV), red cell distribution width (RDW), platelet distribution width (PDW) and CRP in the diagnosis of acute appendicitis (AA). Materials and methods: A retrospective case-controlled study was d...

Introduction The aim of this prospective study was to investigate the diagnostic value of the fibrinogen level, platelet (PLT) count, mean platelet volume (MPV), lymphocyte count, neutrophil/lymphocyte ratio (NLR) and C-reactive protein (CRP) level with white blood cell (WBC) and neutrophil count in acute appendicitis (AA). Methods One hundred and...

Objective: Postoperative iPTH assay may predict significant hypocalcemia after thyroid surgery. The present study aimed to evaluate the ability of iPTH assay to monitor parathyroid function and to identify the risk of postoperative hypocalcemia in patients underwent thyroid surgery. Materials and methods: One hundred patients participated in the...

Elastofibroma dorsi(EFD) is slow-growing, benign, soft tissue tumor of unclear pathogenesis, typically located at the subscapular region of elderly people. It may be unilateral or bilateral. As it exhibits benign behavior, it should be surgically removed only in symptomatic patients. Magnetic resonance imaging (MRI) is a useful tool for assessment...

Background: To investigate the rate of operative success in excision of nonpalpable lymph nodes with metastatic disease achieved with radioguided occult lesion localization (ROLL) and intraoperative ultrasonography (IOUS) in patients with papillary thyroid cancer (PTC). Methods: Twenty consecutive PTC patients with nonpalpable lymph nodes with m...

Objective: The aim of this study is to review our experience with percutaneous ultrasonography (USG) guided thrombin injection to treat iatrogenic femoral artery pseudoaneurysms and to assess the safety of the procedure. Material and Methods: From January 2007 to January 2011, 41 patients with iatrogenic femoral pseudoaneurysms, were included in th...

Objective: Hemoglobinopathy is one of the most widespread inherited disorders in Turkey and preventable with premarital screening programs. The aim of this study was determining the pre- valence of hemoglobinopathies in Kadirli and discussing the necessity of premarital screening in this prevalent region by evaluating the results of premarital scre...

Background: Mesenteric vein thrombosis occurs rarely and is responsible for approximately 5-15% of all cases of acute mesenteric ischemia. The aim of this report was to discuss the management of mesenteric vein thrombosis based on our experience with 34 patients. Methods: In the present study, 34 patients who were admitted to our emergency surge...

A wide variety of drugs have been reported to cause pancreatitis. Although the incidence of drug induced acute pancreatitis is low, the disease is associated with substantial morbidity and mortality, which makes timely identification of the causative agent important. Herein, we report two patients with clinical, biochemical, and radiological eviden...

Introduction: Venous balloon dilation and stent therapy have been proposed as effective treatments for chronic iliofemoral thrombosis. In this study, we report our experience and describe the one-year outcome and efficacy of balloon angioplasty and stenting for the treatment of post-thrombotic syndrome (PTS) in iliofemoral vein segments. Methods:...

Background The aim of the study was to evaluate the local thrombolytic therapy (LTT) in combination with laparoscopy, in management of acute mesenteric ischemia (AMI). Methods From January 2000 to January 2010, patients who were admitted to the hospital with AMI due to acute arterial occlusion were analysed retrospectively. Patients presenting wit...

Background. The purpose of this study was to assess the factors that affect the false-negative outcomes of fine-needle aspiration biopsies (FNABs) in thyroid nodules. Methods. Thyroid nodules that underwent FNAB and surgery between August 2005 and January 2012 were analyzed. FNABs were taken from the suspicious nodules regardless of nodule size. Re...

Introduction: Primary teratomas of retroperitoneum are not usual in the adult population. These tumors most commonly seen at the gonadal and sacrococcygeal regions. Herein we describe a case of an 18-year-old female who had a benign cystic teratoma at the retroperitoneum. Presentation of case: The patient underwent an operation at another hospit...

We reviewed retrospectively TV-related injuries to determine the risk factors, type of injuries, and operative intervention(s) required in children injured by falling TVs. This was a retrospective descriptive study conducted on 42 pediatric patients who were admitted to Istanbul University, Istanbul Medical Faculty, Emergency Surgery Department. Ca...