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Introduction
Current institution
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January 2010 - present
Publications
Publications (60)
Objetivo: Avaliar, dentre os medicamentos mais prevalentemente prescritos nas Unidades de Terapia Intensiva (UTI) de um hospital público de ensino, aqueles que demandam ajuste de dose conforme função renal e apresentar o papel do farmacêutico nesse cenário assistencial. Métodos: Foi realizado um estudo observacional transversal, sendo coletados dad...
Objective
To identify new articles that describe services provided by pharmacists during the first year of the COVID-19 pandemic.
Methods
An update scoping review was conducted in MEDLINE, Embase, Scopus, LILACS, and Google Scholar between 21 May 2020 and 31 May 2021. Study selection and data extraction were performed by two independent authors. D...
Treating multiple myeloma is complex, and providing supportive care through an interdisciplinary approach is essential.
To report and synthesize pharmacists' clinical activities and impact on the care of patients with multiple myeloma.
This was a scoping review that followed the PRISMA-ScR reporting recommendations. A search was conducted in PubMed...
Objective: To evaluate, in the scenario of rapid infusion, the effectiveness of the different regimens of supportive therapy employed in the prevention of nephrotoxicity and electrolyte depletion induced by cisplatin (CDDP). Methods: Data from patients who used CDDP weekly (30 to 40mg/m2) with an infusion time of 60-120 minutes were analyzed. The r...
Objective
To describe the resident pharmacist’s participation in Shared Medical Appointments (SMA) in palliative care.
Methods
The resident pharmacist participated in face-to-face SMA with the attending physician, medical and gerontology students, and a nurse.
Key findings
The resident pharmacist supported interdisciplinary discussions and perfor...
https://www.atheneu.com.br/farmacia-clinica-e-cuidado-farmaceutico-ciencia-educacao-e-pratica-profissional
https://www.atheneu.com.br/farmacia-clinica-e-cuidado-farmaceutico-ciencia-educacao-e-pratica-profissional
Background
Key performance indicators (KPIs) are a set of indicators that improve the quality of services provided by pharmacists. They enable the monitoring and evaluation of result progress and optimize decision-making for stakeholders. Currently, there is no systematic review regarding KPIs for pharmaceutical services.
Objectives
To identify an...
Introdução: O câncer colorretal é o segundo câncer mais incidente na população brasileira e o terceiro com maior taxa de mortalidade. No SUS, a assistência oncológica é custeada via sistema de Autorização de Procedimentos de Alta Complexidade – APAC/Oncologia. Objetivo: Avaliar se o ressarcimento disponibilizado pelo SUS aos centros de tratamento e...
Consolidated and reliable evidence regarding the effectiveness of pharmacist interventions for deprescribing benzodiazepines in older outpatients is lacking.
This study evaluated and summarized the impact of pharmacist interventions on benzodiazepine deprescribing among older outpatients.
A literature search was conducted until August 2022 in PubMe...
Background:
Pharmacy students are at high risk of developing depressive symptoms that can adversely influence their professional future. However, there are no summarized data on the subject.
Objective:
To summarize the prevalence and incidence of depressive symptoms in pharmacy students.
Methods:
A literature search was performed using PubMed,...
Objective
To identify and evaluate the quality of mobile apps available in Brazil focused on the care of patients with anxiety disorders.
Methods
A comprehensive search was conducted until October 2021 on Play Store (Android) and Apple Store (iOS) in Brazil, using the terms “anxiety,” “phobia,” “panic attack,” and “social phobia.” Two independent...
Global healthcare systems, including the National Health System in Brazil – one of the largest public models in the world –, continue to evolve, as well as populations' health needs, currently shaped on individuals feeling a greater desire to manage their own health. Self-care practices are part of several public policies and clinical guidelines in...
Adolescent pregnancy is associated with health, social and economic burdens.
Different strategies have been implemented to prevent this outcome; yet few
updated data on their effectiveness exist. We aim to synthetize the available
evidence on the impact of interventions to delay sexual activity onset in
adolescents by means of a broader systematic...
In book: Adolescent Pregnancy Prevention: Educational Strategies and Implementation Science for Public Health
Introdução: Estima-se que 10 milhões de gestações indesejadas em adolescentes ocorrem todos os anos em países em desenvolvimento, tendo consequências sociais, econômicas e na saúde. Ações educativas, que utilizam conhecimentos estruturados sem necessidade de alta tecnologia, representam tecnologias leve-duras, sendo sua avaliação importante no forn...
Livro de resumos do 2º Congresso Brasileiro de Farmacoterapia e Farmácia Clínica - 2022. A farmácia clínica e a farmacoterapia são áreas do saber por si só transformadoras, já que, através das competências relacionadas ao uso racional de medicamentos e do cuidado ao paciente, tem potencial para mudar vidas. Ao longo dos anos, essas áreas têm agrega...
Objetivos: 1) descrever o processo de gestão de medicamentos judicializados a nível de um hospital terciário, avaliando suas potenciais fragilidades e necessidade de intervenções; 2) avaliar uma amostra do cenário nacional quanto à gestão de medicamentos judicializados, com base nos aspectos previamente elencados a nível institucional. Métodos: No...
O câncer é um conjunto de doenças causadas pela multiplicação descontrolada
de células anormais, sendo a segunda maior causa de morte nos países industrializados, seguida das doenças cardiovasculares. Nesses países, uma em cada quatro pessoas desenvolve câncer (FONTES; CESAR; BERALDO, 2005). No Brasil estima-se que mais de 600.000 pessoas serão dia...
Introdução: A baixa adesão ao tratamento com antineoplásicos orais reflete a necessidade de medidas que facilitem o cumprimento da terapia, como a provisão de materiais educativos. Objetivo: Desenvolver e validar cartilhas orientando o uso dos medicamentos tamoxifeno, anastrozol e capecitabina no tratamento do câncer de mama. Método: Para a definiç...
Objectives: To assess if the antiemetic prophylaxis prescribed to patients exposed to chemotherapy is following the Antiemesis guideline published by the National Comprehensive Cancer Network (NCCN) version 3.2018. Methods: A medication review was performed, considering antiemetic´s prescriptions of adult patients under treatment with moderate and...
Introduction:
Cardiovascular diseases are the main cause of mortality worldwide, and systemic arterial hypertension is associated with a large number of these cases. The objective of health professionals and health policies should be searching for the best therapeutics to control this disease. A recent consensus indicated that β-blockers have rece...
Objectives:
This is a randomized controlled trial that aims to evaluate the impact of pharmacist-led discharge counseling on reducing pharmacotherapy problems in the 30-day postdischarge period of cardiology patients from a tertiary hospital in Brazil.
Methods:
At discharge, two cardiovascular pharmacy residents performed a medication counseling...
Aims
Despite their overall favourable safety profile, tyrosine kinase inhibitors (TKIs) are related to severe adverse events including haematological toxicities such as anaemia, leucopenia, neutropenia and thrombocytopenia. We designed a systematic review and network meta‐analysis of randomised controlled trials to compare safety among TKIs (bosuti...
Background The Cochrane collaboration risk of bias assessment (RoB) tool is used in several fields to evaluate the methodological quality of studies. Its strengths and challenges are discussed. Objective To assess the sensitivity of the RoB tool in studies of pharmacist interventions. Setting DEPICT database was used to pool randomized controlled t...
Background:
Transitions of care can contribute to medication errors and other adverse drug events.
Purpose:
The aim of this study was to evaluate the impact of pharmacist-led discharge counseling on hospital readmission and emergency department visits through a systematic review and meta-analysis.
Edata sources:
Lectronic searches were perform...
The definition of antineoplastic administration sequences can help planning of therapeutic regimens in a more rational way, and thus optimize chemotherapy effects on patients, increasing efficacy and reducing toxic effects. In this way, this study aimed to evaluate the infusion order of antineoplastic agents of the main therapeutic protocols used i...
OBJECTIVES
This study aimed to evaluate the impact of pharmacist-provided discharge counseling on mortality rate, hospital readmissions, emergency department visits, and medication adherence at 30 days post discharge.
METHODS
This randomized controlled trial was approved by the local ethics committee and included patients aged 18 years or older ad...
Objective:
Pharmacists have adopted an active role in asthma management. This review aimed to analyze the intervention dose, understood as the "amount of program delivered," and core components of the intervention provided by pharmacists in asthma management.
Data sources:
A literature search was conducted in December 2016 using PubMed.
Study s...
Rationale, aims, and objectives
Discharge medication counselling has produced improved quality of care and health outcomes, especially by reducing medication errors and readmission rates, and improving medication adherence. However, no studies have assembled an evidence‐based discharge counselling process for clinical pharmacists. Thus, the present...
Systematic reviews and pairwise meta-analyses of randomized controlled trials, at the intersection of clinical medicine, epidemiology and statistics, are positioned at the top of evidence-based practice hierarchy. These are important tools to base drugs approval, clinical protocols and guidelines formulation and for decision-making. However, this t...
Objective
To implement a clinical pharmacy service focused on the comprehensive review of antineoplastic drugs used in therapy of hematological diseases.
Methods
An interventional study was conducted in a Brazilian tertiary teaching hospital in two different periods, with and without a clinical pharmacy service, respectively. This service consiste...
Background:
Cardiovascular disease (CVD) is the leading cause of death worldwide and has a substantial impact on people's health and quality of life. CVD also causes an increased use of health care resources and services, representing a significant proportion of health care expenditure. Integrating evidence-based community pharmacy services is see...
A critical analysis of the research on clinical pharmacy services with regards to study characteristics has not been undertaken since 1998. However, several meta-analyses have been conducted to demonstrate the impact of pharmacists’ interventions in specific medical conditions. These meta-analyses present high heterogeneity in part because the inte...
The objective of this systematic review was to evaluate the impact of pharmacists' interventions on clinical asthma outcomes on adult patients and to identify the outcome indicators used.
PubMed, Scopus, Web of Science and Scielo were searched. Studies addressing pharmacists' interventions on adult asthma patients reporting clinical asthma outcomes...
Background:
Multiple reviews have evaluated the impact of pharmacist-delivered patient care on health-related outcomes. However, it is unclear which of the pharmacist-delivered interventions in these services are the most effective. Aim of the review To gather the evidence of the impact of clinical pharmacy services on the medication use process o...
DEPICT (Descriptive Elements of Pharmacist Intervention Characterization Tool) was created in response to the frequently reported issue of poor intervention description across studies assessing the impact of clinical pharmacy activities. The aim of this study was to create an improved version of DEPICT (i.e. DEPICT 2) to better characterize clinica...
This study evaluated the drug-related morbidity and mortality in Brazil, its prevalence, the pharmacological groups and risk factors associated. We performed a systematic review of observational studies published up to August 2012, without restriction start date, in the databases Medline, Lilacs, SciELO, EMBASE, IPA, Science Direct, Scopus and Web...
Background Pharmacists' counseling has improved health-related outcomes in many acute and chronic conditions. Several studies have shown how pharmacists have been contributing to reduce morbidity and mortality related to drug-therapy (MMRDT). However, there still is a lack of reviews that assemble evidence-based clinical pharmacists' counseling. Eq...
This chapter on athlete's foot contains sections titled Background, Questions, and References. The Background includes the subheadings, definition of the disease, incidence/prevalence, etiology, diagnostic tests, aims of treatment, relevant outcomes, and methods of search (of systematic reviews and randomised clinical trials). The relevant answerab...
We conducted a systematic review and metaanalysis of randomized placebo-controlled trials in moderate-to-severe psoriasis treated with biological agents, with a follow-up of 10-14 weeks. Overall, 41 studies, with mean Jadad score of 4.4, and 15,586 patients were included. For the efficacy outcomes PASI 50, 75 and 90 our findings are not conclusive...
In Reply
Our systematic review and mixed-treatment comparison meta-analysis showed no significant differences among 14 topical antifungal agents for mycologic cure.¹ We also have found that butenafine, naftifine, and terbinafine might be the best treatments for maintaining a cure in patients with dermatophytosis.¹ German language randomized clinica...
Background:
The complexity of clinical pharmacy services usually leads to an inconsistent or even poor description of their interventions in scientific reports. To ensure comparability and reproducibility of the evidence, an in-depth description of pharmacist interventions is required.
Objective:
To validate a new tool called DEPICT (Descriptive...
Importance:
Considering that most randomized controlled trials compare antifungals with placebo instead of other antifungals, conventional meta-analysis is insufficient to define superiority between the evaluated strategies. To our knowledge, this is the first mixed-treatment comparison meta-analysis on antifungal treatments in the literature and...
To compare the efficacy of nucleoside or nucleotide analog monotherapy for the treatment of chronic hepatitis virus B (HBV) with adefovir dipivoxil, entecavir, lamivudine, telbivudine, and tenofovir disoproxil fumarate.
Mixed-treatment comparison meta-analysis of nine randomized controlled clinical trials.
A total of 3972 adults with a diagnosis of...
To evaluate and compare the efficacy of topical antifungal drugs applied to the treatment of each dermatomycosis.
A systematic review of randomized clinical trials, published in Portuguese, Spanish and English until July 2010, which compared the use of azole and allylamine antifungal drugs among themselves and with placebo in the treatment of cutan...
The analysis of comparative efficacy and safety of topical antifungals in the literature is restricted to the treatment of tinea pedis and onychomycosis. Therefore our objective was to evaluate and compare the efficacy and safety of topical antifungals used in the treatment of dermatomycosis, we performed a comprehensive search for randomized contr...
