In-Sung Yeo

Verified

In-Sung verified their affiliation via an institutional email.

Learn more

Verified

In-Sung verified their affiliation via an institutional email.

Learn more

• DDS, MSD, PhD
• Professor (Full) at Seoul National University

Considerable effort has been directed towards replacing lost teeth using tissue-engineering methods such as titanium implants. A number of studies have tried to modify bioinert titanium surfaces by coating them with functionally bioactive molecules for faster and stronger osseointegration than pure titanium surfaces. Recently, peptides have been re...

Purpose: This retrospective study compared the long-term outcomes of dental implants according to type of connection and surface. Materials and methods: Multiunit restorations were classified as follows: an external connection with a turned surface, an external connection with an anodized surface, or an internal connection with a fluoride-modifi...

Anatomically, the human tooth has structures both embedded within and forming part of the exterior surface of the human body. When a tooth is lost, it is often replaced by a dental implant, to facilitate the chewing of food and for esthetic purposes. For successful substitution of the lost tooth, hard tissue should be integrated into the implant su...

Graphene, a nanomaterial made of sp2 hybridized carbon atoms, has recently been investigated as a novel surface treatment for promoting osseointegration. This study aims to evaluate the biological effects of graphene oxide (GO) on turned and sandblasted, large-grit, and acid-etched (SLA) titanium surfaces. In vitro, bone marrow stromal cells (BMSCs...

Smile design has transitioned from traditional analog methods to modern digital techniques. This case report presents a smile design technique using a digital workflow facilitated by an application on smart devices as a reference. This approach enables real-time chairside modifications, incorporating the patient's preferences. Furthermore, it impro...

Implantable medical devices and prostheses are inherently recognized as foreign bodies by the human body [...]

An implant-retained maxillofacial overdenture with a pharyngeal speech aid prosthesis was fabricated for a patient with a nonsurgically treated cleft palate who was unable to achieve velopharyngeal closure. Computer-aided design and computer-aided manufacturing were used to fabricate a metal-reinforced prosthesis using the Ivotion Denture System an...

This study aimed to investigate the effects of sandblasting on the physical properties and bond strength of two types of translucent zirconia: niobium-oxide-containing yttria-stabilized tetragonal zirconia polycrystals ((Y, Nb)-TZP) and 5 mol% yttria-partially stabilized zirconia (5Y-PSZ). Fully sintered disc specimens were either sandblasted with...

Statement of problem. Selecting the sterilization method is important because sterilization can alter the surface chemistry of implant materials, including zirconia, and influence their cellular biocompatibility. Studies on the biological effects of sterilization on implant materials are lacking. Purpose. The purpose of this in vitro study was to...

The bone integrates with the implant surface to successfully replace a lost tooth. The microtopography and chemistry of the implant surface have been investigated to enhance osseointegration. Various topographical, physical, and chemical modifications have been applied to the commercially pure grade 4 titanium implant surface, which appear to influ...

Background It is common for dental technicians to adjust the proximal surface of adjacent teeth on casts when fabricating single crowns. However, whether the accuracy of the proximal contact is affected if this step is eliminated is unclear. Objective To evaluate the accuracy of the proximal contact of single crowns for mandibular first molars fab...

Purpose The purpose of this in vitro study was to investigate the antibacterial effect and biocompatibility of silver coatings via aerosol deposition on titanium and zirconia surfaces. Methods The surfaces of titanium and zirconia specimens were polished and coated with silver via aerosol deposition. After silver coating, the elemental composition...

The aim of this study was to investigate the surface characteristics and evaluate the bone-implant interfaces of injection molded zirconia implants with or without surface treatment and compare them with those of conventional titanium implants. Four different zirconia and titanium implant groups (n = 14 for each group) were prepared: injection-mold...

The optical property of 3 mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP) is affected by various factors. This study aimed to evaluate the effects of phase fraction of zirconia polymorphs and grain size on the translucency of 3Y-TZP. Disk-shaped 3Y-TZP specimens were fabricated. Eight groups were established based on their final sin...

The interface between a dental implant and an abutment is stabilized by two mechanical characteristics: a preload of an abutment screw and the friction between the contact surfaces of the implant and the abutment. These mechanical properties are quantitatively analyzed by using physical and mechanical formulas. The important thing is that such mech...

Background/purpose Dental implants are inevitably exposed to bacteria in oral cavity. Understanding the colonization of bacteria on implant surface is necessary to prevent bacteria-related inflammation surrounding dental implants. The purpose of this study was to investigate the effect of surface properties on biofilm formation on the implant surfa...

There are often different interpretations by clinicians, manufacturers, and researchers regarding what defines a bioactive material. This has led to confusion amidst varying claims by individual stakeholders. Unlike the more traditional passive materials, bioactive materials are designed to elicit a desired therapeutic or beneficial response. Such...

PURPOSE: This in vitro study aimed to evaluate the surface characteristics of a full veneer crown fabricated chairside (CS) from a (Y, Nb)-TZP zirconia block in response to conventional zirconia grinding and polishing. MATERIALS AND METHODS: Zirconia crowns (n = 40) were first prepared and divided into two groups of materials: Labside (LS) and CS,...

Now it is right in the digital age. Everything in the world seems to be rebuilt inside the computer. Digital technology have been already close to us and we have to feel that trend in the field of dentistry. Especially, dental prosthodontics and clinical implantology have taken the lead in adopting digital technology, and now clinical restorative p...

Histological analysis is considered to be the gold standard method of evaluating osseointegration around a bone-implant. However, this method requires invasive specimen preparation and is capable of representing only one plane. By comparison, micro-computed tomography (μCT) is a fast and convenient method that offers three-dimensional information b...

Surface characteristics are an important factor for long-term clinical success of dental implants. Alterations of implant surface characteristics accelerate or improve osseointegration by interacting with the physiology of bone healing. Dental implant surfaces have been traditionally modified at the microlevel. Recently, researchers have actively i...

Establishing aesthetic outcomes in peri-implant soft tissues of anterior implants is challenging for many clinicians. In this report, a 23-year-old woman with prolonged retention of the primary mandibular right central incisor was referred after completing orthodontic treatment. A one-piece mini-implant was immediately placed after extraction using...

Statement of problem: Interim restorations are often used along with mouth rinses during the healing period following surgical procedures. However, evidence regarding the color and surface properties of digitally fabricated interim restorations after oral rinsing is lacking. Purpose: The purpose of this in vitro study was to evaluate whether differ...

This was one of the presentations invited in a Symposium entitled, 'Bioactive Dental Materials - Developing, Promising, Confusing'.

Purpose Osseointegration consists of bidirectional bone formation around modified implant surfaces by contact osteogenesis and distance osteogenesis. This study tested whether contact osteogenesis on the surface of a modified titanium (Ti) implant is stimulated by cytokines in the blood. Methods In the first two types of experiments, sandblasted,...

With the development of digital dentistry, it is being applied in various ways of dental treatment. This case report presents the definitive prosthesis designed in advance with a re-established vertical dimension and the digital technology, which determined the amount of tooth preparation, in order to preserve as much tooth structure as possible in...

Installation of dental implants at optimal angles and positions is critical in longterm stable implant-supported restorations. Surgery and prosthodontic procedures should be performed accurately as the treatment is planned. In this clinical case, Computer aided design and manufacturing technology was used not only to establish a precise surgical pl...

The dental implant relies on osseointegration and the response of bone to the implant surface. This process comprises bidirectional bone formation, including bone deposition on the implant surface toward the existing bone (contact osteogenesis) and vice versa (distance osteogenesis). It is unclear whether these processes are independent or whether...

The aim of the present study was to evaluate the in vivo bone response to an additively manufactured zirconia surface compared to osseointegration into titanium (Ti) surfaces. Scanning electron microscopy, confocal laser scanning microscopy, and electron spectroscopy for chemical analysis were performed to assess the surface characteristics of impl...

Purpose: This study aimed to find a correlation between the occlusal plane and two reference planes that are frequently used in semi-adjustable articulators. Materials and Methods: Sixty-two males and fifty females with normal articulation were recruited and the lateral cephalograms of these patients were taken. The angles between the Frankfort hor...

PURPOSE The purpose of this in vitro study was to investigate the wear resistance and surface roughness of three interim resin materials, which were subjected to chewing simulation. MATERIALS AND METHODS Three interim resin materials were evaluated: (1) three-dimensional (3D) printed (digital light processing type), (2) computer-aided design and c...

Panoramic radiographs, also known as orthopantomograms, are routinely used in most dental clinics. However, it has been difficult to develop an automated method that detects the various structures present in these radiographs. One of the main reasons for this is that structures of various sizes and shapes are collectively shown in the image. In ord...

Fifteen participants (9 male, 6 female) received a total of 15 monolithic single restorations made from fully sintered (Y, Nb)-TZP (tetragonal zirconia polycrystal) block. The restorations were clinically evaluated for survival, success rate, and periodontal probing depths 6 months after the insertion of the restorations. Esthetic, functional, and...

Determining the peri-implant marginal bone level on radiographs is challenging because the boundaries of the bones around implants are often unclear or the heights of the buccal and lingual bone levels are different. Therefore, a deep convolutional neural network (CNN) was evaluated for detecting the marginal bone level, top, and apex of implants o...

A three-dimensional (3D) intraoral scanner, which is one of the major developments in digital dentistry, is widely used in fixed prosthodontics. The application of intraoral scanner is now increasing in removable prosthodontics. Sclerotic change induced by scleroderma causes the limitation of mouth opening and multiple loss of the teeth. Convention...

Dental implants should be placed at ideal sites for implant-supported restorations. For a patient with insufficient residual ridge, mouth preparation including surgical intervention can be indicated to establish a soft and hard tissue environment favorable for a definitive prosthesis. Prosthodontic design based on computer-guided surgery and comput...

The Special Issue, “Dental Implant Materials 2019”, has tried to introduce recent developments in material science and implant dentistry with biologic and clinical aspects [...]

A connection structure using both a screw and friction is advantageous to secure an abutment to an implant. Understanding the biomechanics of the implant-abutment connection is necessary for the long-term clinical survival of a dental implant with decreased complications. The internal conical friction connection structure and micro-threads have sho...

Translucent zirconia, manufactured by increasing the yttria content, offers improved translucency, but may have a negative effect on esthetic outcomes under clinical conditions such as discolored abutment because of the reflection of the underlying color. The purpose of this in vitro study was to compare the translucency parameter and masking abili...

Computer-aided design and manufacturing technology has been closely associated with implant-supported restoration. The digital system employed for prosthodontic restorations comprises data acquisition, processing, and manufacturing using subtractive or additive methods. As digital implantology has developed, optical scanning, computer-based digital...

High‐translucency restorative materials are commonly used in the restoration of anterior teeth where aesthetics is a critical factor. In this in vitro study, the impact of mouthwash on the colour stability and surface characteristics of high‐translucency computer‐aided design and computer‐aided manufacturing (CAD‐CAM) dental restorative materials w...

Peri-implantitis is an inflammatory disease that results in bone destruction around dental implants. A preclinical study using beagle models is frequently performed prior to clinical application in dentistry. Previously, we proposed an immediate peri-implantitis experimental model with a shorter experimental duration and less expense than the conve...

Early implant loading is very important for reducing the duration of missing teeth in human patients. The laminin‐derived peptide, DLTIDDSYWYRI motif (Ln2‐P3), accelerates bone healing. Therefore, to investigate the hypothesis that Ln2‐P3 increases the bone response to sandblasted, large‐grit, acid‐etched (SLA) titanium implants, the effect of the...

Rationale: The iliac bone graft procedure is one of the treatment options for individuals with extremely resorbed alveolar bones. An autogenous block bone graft can allow the use of an implant-supported fixed dental prosthesis, rather than conventional removable dentures, by completely edentulous patients. However, the iliac bone graft technique i...

Background: Leukocyte- and platelet-rich fibrin (L-PRF) has been suggested to enhance bone healing and the effects of L-PRF need to be evaluated in lateral residual alveolar bone augmentation. This in vivo study aimed to analyze the effects of L-PRF as a membrane on bone regeneration in lateral residual alveolar augmentation. Methods: Eight mong...

The stability of peri-implant tissue is essential for the long-term success of dental implants. Although various types of implant connections are used, little is known about the effects of the physical mechanisms of dental implants on the stability of peri-implant tissue. This review summarizes the relevant literature to establish guidelines regard...

With the evolution of the computer-aided design/computer-aided manufacturing (CAD/CAM) technology, the intraoral scanners are playing an increasingly important role, as they are the first step towards a completely digital workflow. The CAD/CAM double scanning technique has been used to transfer the information from provisional restorations to defin...

This review paper describes several recent modification methods for biocompatible titanium dental implant surfaces. The micro-roughened surfaces reviewed in the literature are sandblasted, large-grit, acid-etched, and anodically oxidized. These globally-used surfaces have been clinically investigated, showing survival rates higher than 95%. In the...

Introduction: A resected mandibular edentulous ridge resulting from an ameloblastoma and marginal mandibulectomy is a restorative challenge. To maintain oral hygiene, recurrent examinations, and for long-term maintenance, a removable dental prosthesis is preferred to an implant-supported fixed dental prosthesis. Patient concerns: A 28-year-old A...

Rationale: Full-mouth rehabilitation of patients with bruxism and severely worn dentition poses a great challenge to clinicians. Several treatment planning methods and restorative materials are used to treat tooth wear in modern dentistry. Clinicians should be able to select the most suitable treatment planning methods and materials for individual...

In this study, we evaluated early bone responses to a vitronectin-derived, minimal core bioactive peptide, RVYFFKGKQYWE motif (VnP-16), both in vitro and in vivo, when the peptide was treated on sandblasted, large-grit, acid-etched (SLA) titanium surfaces. Four surface types of titanium discs and of titanium screw-shaped implants were prepared: con...

This study reported the treatment of a patient with excessive worn dentition and limited maxillo-mandibular space for restoration, utilizing the computer-aided design and computer-aided manufacturing (CAD/CAM) technology. After the thorough examination of the patient's occlusal vertical dimension (OVD), full mouth rehabilitation was planned with in...

Purpose: Nature of bone–implant interface remains unknown. Histologic findings from undecalcified specimens using light microscopes are helpful to understand the interface. However, other resources are still needed. This presentation introduces some approaches to evaluating quality of the interface: X-ray microtomography-based three-dimensional (3D...

Research on whether the number or location of missing teeth affects the accuracy of intraoral scanners in partial edentulous patients is scarce. This study aimed to evaluate the precision of complete-arch scan data of various partial edentulous arches acquired by intraoral scanners. Five different maxillary models were scanned using Carestream CS36...

Objective: The purpose of this study was to measure the 3-dimensional (3D) bone-to-implant contact (BIC) ratios calculated with an associated software algorithm on 3D micro-computed tomography (μCT) scans and compare them with measurements made with 2-dimensional histomorphometry. Study design: For uncomplicated calculation of the 3D BIC ratios,...

Ultraviolet (UV) photofunctionalization has been suggested as an effective method to enhance the osseointegration of titanium surface. In this study, machined surface treated with UV light (M + UV) was compared to sandblasted, large-grit, acid-etched (SLA) surface through in vitro and in vivo studies. Groups of titanium specimens were defined as ma...

Statement of problem: The effect of different build angles on the tissue surface adaptation of complete denture bases manufactured by digital light processing (DLP) is unclear. Purpose: The purpose of this in vitro study was to evaluate the effect of build angle on the tissue surface adaptation of DLP-printed complete denture bases. Material an...

Purpose: This study aimed to evaluate the effect of two different implant-abutment connection structures with identical implant design on peri-implant bone level. Materials and methods: This clinical study was a patient-blind randomized controlled trial following the CONSORT 2010 checklists. This trial was conducted in 24 patients recruited betw...

It is challenging to remove dental implants once they have been inserted into the bone because it is hard to visualize the actual process of bone formation after implant installation, not to mention the cellular events that occur therein. During bone formation, contact osteogenesis occurs on roughened implant surfaces, while distance osteogenesis o...

Esthetic restorations using highly translucent ceramics powered by chairside digital dentistry are becoming popular. The purpose of this in vitro study was to investigate the impact of ultrasonic scaling on the optical and surface properties of highly translucent ceramic materials for digital dentistry. A resin nanoceramic (Lava Ultimate; LU), dual...

We evaluated the shear bond strength of bone–implant contact, or osseointegration, in the rabbit tibia model, and compared the strength between grades 2 and 4 of commercially pure titanium (cp-Ti). A total of 13 grades 2 and 4 cp-Ti implants were used, which had an identical cylinder shape and surface topography. Field emission scanning electron mi...

This in vitro study investigated the impact of various dentifrices on the shade, translucency, gloss, and surface characteristics of polishing- or glazing-finished monolithic zirconia surfaces after simulated toothbrushing. Eighty square-shaped monolithic zirconia specimens were divided into two major groups based on the finishing methods—polished...

Purpose: The goal of this study was to compute the estimated cumulative survival and success rates of alumina-toughened zirconia (ATZ) abutments used for external connection-type implant-supported fixed dental prostheses (FDPs) after a mean follow-up of 6.9 years (82.3 months). Materials and methods: From May 1998 to July 2016, patients who prov...

Computer aided design and manufacturing and implant surgery using a guide template improve restoration-driven implant treatment procedures. This case utilized those digital technologies to make definitive prostheses for a patient. According to the work flow of digital dentistry, cone beam computed tomography established the treatment plan, which wa...

PURPOSE This study tried to find the most significant factors predicting implant prognosis using machine learning methods. MATERIALS AND METHODS The data used in this study was based on a systematic search of chart files at Seoul National University Bundang Hospital for one year. In this period, oral and maxillofacial surgeons inserted 667 implant...

Purpose: This study aimed to investigate the in vitro and in vivo bone-forming potential of a sandblasted, large-grit, acid-etched (SLA) titanium (Ti) surface treated with a laminin-derived functional peptide, PPFEGCIWN (DN3). Materials and methods: Human osteoblast-like MG63 cells were cultured with SLA Ti discs untreated or treated with DN3 or...

Screw loosening is one of the most frequent complications in implant-supported restoration. However, many dental clinicians misunderstand the exact mechanism of screw loosening. Screw loosening can trigger peri-implantitis more severely than what dental clinicians usually think. Just a change of abutment screws cannot solve this complication. The d...

Purpose: This in vivo study used control variable implants to compare early bone responses in fluoride-modified (F-mod) and hydrophilic, sandblasted, large-grit, acid-etched (modSLA) surface implants that differed in implant design. Materials and methods: Four different types of implants (n = 24) were prepared: F-mod surface with Astra Tech impl...

Purpose Bone-to-implant contact (BIC) is difficult to measure on micro-computed tomography (CT) because of artifacts that hinder accurate differentiation of the bone and implant. This study presents an advanced algorithm for measuring BIC in micro-CT acquisitions using a spiral scanning technique, with improved differentiation of bone and implant m...

This study investigated the influences of acidity, ethanol, and pigment on the optical properties, microhardness, and surface roughness (Ra) of a nanohybrid dental composite resin. A total of 108 disc-shaped specimens were fabricated using a nanohybrid dental composite and allocated into 36 different storage solutions according to the levels of pH...

Screw loosening, which is closely associated with the preload of an abutment screw, is one of the most frequent complications in clinical implantology. The aim of the present study was to investigate the preload prediction of a joint screw assembly between an implant and abutment based on a mechanical analysis. A mechanical formula was determined t...

Purpose Contact and distance osteogenesis occur around all endosseous dental implants. However, the mechanisms underlying these processes have not been fully elucidated. We hypothesized that these processes occur independently of each other. To test this, we used titanium (Ti) tubes to physically separate contact and distance osteogenesis, thus all...

Purpose: Avoiding excessive trauma--thermal or otherwise--during dental implant site preparation is considered critical to implant success; overheating is considered to be a major cause of bone necrosis. Studies evaluating thermal and mechanical effects of implant drill design are limited, and effects of flute design have not been accounted for. T...

Using the digital technology, monolithic zirconia implant restoration, which has minimum amount of interference during the lateral excursive movement, can be fabricated from intraoral scan data with the help of virtual articulator function in the dental CAD software. In this case report, three implant cases were successfully finished by fabricating...

This study analyzed volatility comovement and contagion in the stock markets of four countries (China, Japan, Korea, and Taiwan) in East Asia, which are closely connected with each other geographically and economically in terms of short-term and long-term perspectives. The volatility of stock returns has complex properties of not only volatility cl...

A recent study on implantology reported a statistical linear correlation between two measures at the bone-implant interface: Periotest evaluation of the damping effect at the interface and resonance frequency analysis. The publication formulated a linear function of the dependent variable, the Periotest value (PTV), to the independent variable, the...