Imran Ghani

East Coast Community Healthcare CIC

Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenual area. Therefore, target subtotal resections usin...

Study Design Retrospective cohort study. Objectives Intraoperative neurophysiological monitoring (IONM) is widely used in spinal neurosurgery, particularly for intramedullary tumours. However, its validity in intradural extramedullary (IDEM) spinal tumours is less clearly defined, this being the focus of this study. Methods We compared outcomes f...

AIMS 5-ALA (Gliolan©) is a valuable surgical tool used predominantly in high grade tumours, which utilises tissue fluorescence to improve the visualisation of the brain-tumour interface. This ensures safe maximal resection, while preserving healthy brain. While Gliolan© use in low grade tumours has previously been reported with variable results, re...

Objective: Intradural-extramedullary tumours are rare tumours. Advancements in imaging, surgical techniques, and intraoperative monitoring has led to greatly improved prognosis over the years. However, it is difficult to establish specific guidelines for diagnosis and management of IDEM tumours. We present a clinical case series of surgically opera...

Method Results • Our LD infection rate over 10 years in 450 patients is 14%. • Factors associated with increased incidence of LD infection • Time between LD insertion and removal (unadjusted OR 1.884 [1.330, 2.668]) • Number of CSF samples (unadjusted OR 8.877[4.975, 15.840]). • Factors associated with reduced incidence of lumbar drain infection •...