Ilkka Vuori

Ilkka Vuori
Tampere University | UTA

Doctor of Medicine

About

338
Publications
32,276
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22,965
Citations
Citations since 2016
5 Research Items
5190 Citations
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800
20162017201820192020202120220200400600800

Publications

Publications (338)
Chapter
Scientific evidence indicates that practicing regular moderate-intensity aerobic physical activities such as walking and cycling is associated with preventive benefits by decreasing the risk of many common diseases, and systematic aerobic exercise training is often beneficial as part of the treatment or rehabilitation for many chronic conditions. O...
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Full-text available
The World Health Organization (WHO) is a respected name as the global leader in the fight against critical health challenges such as malaria, tuberculosis, HIV, and noncommunicable diseases. Because of the great impact of WHO in influencing various health matters, there is wide interest and intensive effort to include new and important health issue...
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Full-text available
Without effective countermeasures, the musculoskeletal system is altered by the microgravity environment of long-duration spaceflight, resulting in atrophy of bone and muscle tissue, as well as in deficits in the function of cartilage, tendons, and vertebral disks. While inflight countermeasures implemented on the International Space Station have e...
Article
There is great need to increase health-enhancing physical activity in most populations. At individual and group level, guidance provided by health professionals can be effective. The primary health care system (PHCS) is in principle a favorable channel to provide physical activity (PA) counseling, but in reality this service is offered to only a sm...
Article
Single healthy living habits such as non-smoking and regular physical activity decrease the risk of common non-communicable diseases, unsuccessful aging and premature death to a small to moderate degree. Their cumulative effects are, however, large. Only a small minority of people adhere well to all healthy living habits or even the healthiest ones...
Article
Full-text available
Purpose: This randomized controlled study was designed to investigate the effects of a 4-month whole body vibration-intervention on muscle performance and body balance in young, healthy, nonathletic adults. Methods: Fifty-six volunteers (21 men and 35 women, aged 19-38 yr) were randomized to either the vibration group or control group. The vibratio...
Article
Physical activity (PA) and exercise training (ET) have great potential in the prevention, management, and rehabilitation of a variety of diseases, but this potential has not been fully realized in clinical practice. The health care system (HCS) could do much more to support patients in increasing their PA and ET. However, counseling on ET is not us...
Article
Physical activity (PA) is healthy, and it offers a practical and safe means to decrease substantially the burden of diseases. However, due to lack of sufficient PA in most populations, this potential is in partial use only. The health care system should support the patients and the population at large to increase their PA to sufficient level for he...
Article
To determine which approaches promote cycling, the size of the effects, and whether there are associated benefits on physical activity or anthropometric measures, by means of a systematic review. Intervention studies with a cycling outcome measure were identified from searches of 13 databases, previous systematic reviews, Web sites, and reference l...
Article
Lähtökohdat Bioimpedanssin avulla on mahdollisuus mitata dialyysipotilaiden kuivapainoa ja ravitsemustilaa. Suuri osa hemodialyysipotilaista ei ole oikeassa kuivapainossa, mikä vaikeuttaa dialyysihoidon toteuttamista ja lisää kuolleisuutta. Kuivapainon kliininen määrittäminen on epävarmaa. Menetelmät Järjestelmällisellä kirjallisuushaulla haettiin...
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This study examined the associations of body mass index (BMI), waist circumference (WC), and cardiorespiratory fitness (CRF) with incident functional limitation (IFL) in adults. Patients (n = 2400), 30+ years [mean age, 45.2 (SD, 8.3); 12% women], completed a baseline health examination during 1979 to 1995. CRF was quantified by age-and sex-specifi...
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Full-text available
A rapid increase in economic well-being and urbanization in Kuwait have been accompanied by profound changes in lifestyle, including low levels of physical activity in all population groups. These changes have contributed to a high prevalence of overweight and obesity and to the escalation of the non-communicable disease rates, particularly coronar...
Article
Bone mineral density (BMD) and clinical status of 42 patients treated surgically 10–11 years earlier for an acute knee ligament injury were determined. The BMD was measured at the spine (L2–4) and the femoral neck, distal femur, patella, proximal tibia, and calcaneus of both lower extremities using dual-energy x-ray absorptiometric (DXA) scanner. T...
Article
This paper summarizes the evidence on the relationship between physical activity (PA) and cardiovascular disease (CVD) that has been published mainly during the past 10 years. The primary focus is on aspects related to the primary prevention of the clinical events of coronary heart disease and stroke. The material was collected by conducting a sear...
Article
Three hundred and thirty healthy Finnish girls and premenopausal women, aged 7-47 years, were examined to evaluate the natural development of bone mineral mass and density from early childhood to menopause. Bone mineral content (BMC,g) and areal density (BMD, g/cm2) were measured from the spine (L2-L4), femoral neck, trochanter region of the femur,...
Article
The first objective of this study was to design a hip protector that would effectively attenuate and shunt away from the greater trochanter the impact energies created in typical falls of the elderly. As the shock absorption material, the protector included the 12 mm-thick Plastazote, which was found to be the most efficient energy-absorbing materi...
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After an immobilization period of 3 weeks, the effects of free remobilization (8 weeks) as well as low- and high-intensity treadmill running on the bone mineral content (BMC) and density (BMD) of the hindlimbs of Sprague-Dawley rats (n = 70) were studied using a dual-energy x-ray absorptiometric scanner. In the low-intensity running program, the ra...
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The aim of this study was to review studies reporting cost-effectiveness of exercise-based interventions in treatment of various diseases. Systematic literature search using several databases. Abstracts initially screened independently by two authors, full-text articles again evaluated by two authors, who decided whether an article should be includ...
Article
The purpose of this study was to determine and compare the force attenuation properties of various external trochanteric padding materials under in vitro conditions simulating characteristic falling of the elderly. The selected materials had to be practically suitable for external hip padding so that the main criteria for the materials were good en...
Article
Currently, chronic non-communicable diseases, notably metabolic and cardiovascular diseases, are a major health-related burden of the populations of the industrialized and increasingly so also of the non-industrialized countries. Physical inactivity is one of the living habits that have been shown to be causally related to the most common metabolic...
Article
This study evaluated the effects of long-term unilateral physical activity (tennis) on the playing arm humerus. Total lengths of both humeri, site-specific widths, and the bone mineral contents (BMC) at the proximal, middle, and distal parts of the bones were measured using dual-energy X-ray absorptiometry (DXA). Bone mineral apparent density (BMAD...
Article
Poor glucose control increases the risk of vascular complications and cardiovascular mortality in patients with diabetes mellitus (DM). Our aim was to evaluate the efficacy of a long-term exercise training program on metabolic control and arterial stiffness in patients with type 2 DM. Fifty men with DM (age 52.3 +/- 5.6 years) were randomly assigne...
Article
The aims of this study were to examine the effects of 12 months unilateral high-resistance strength training and 8-month detraining on bone mineral content (BMC), density (BMD) and estimated mechanical characteristics of upper limb bones, and also to estimate consequent loading induced strains on forearm bone shafts. Thirteen female physiotherapy s...
Article
The long-term effects of bone fractures on bone mineral density (BMD) at various skeletal sites are poorly established, although a serious fracture, such as a tibia fracture, followed by long immobility and disuse may lead to permanently decreased BMD and, through this mechanism, may be a risk factor for osteoporotic fractures in later life. To det...
Article
Type 2 diabetes mellitus (DM) enhances the development of atherosclerosis and reduces the activity of the oxidative myeloperoxidase (MPO) enzyme. MPO gene has a functional promoter polymorphism -463G/A which leads to high- (GG) and low-expression (AG, AA) genotypes. We studied the association of MPO polymorphism with carotid artery intima-media thi...
Chapter
Classical referenceCardiovascular diseaseIntroductionOsteoporosis and related fracturesPhysical activity and low back painOverweight and obesityType 2 diabetesHypertensionCancerImmune systemMental healthMultiple choice questions
Chapter
IntroductionBone turnoverMechanical adaptation of boneOther factors modifying bone adaptation to mechanical loadingMethodological considerationsBone mineral density and content in female athletesConclusion Recommendations for future research
Article
Several stress echocardiography (SE) modalities have been introduced for diagnosing coronary artery disease (CAD). Exercise and dobutamine SE are commonly considered to have a better diagnostic accuracy than vasodilator SE. The purpose of this study was to assess the agreement between the test results and the segmental concordance between three SE...
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Full-text available
Myocardial diastolic tissue velocities are reduced already in newly onset Type 2 diabetes mellitus (T2D). Poor disease control may lead to left ventricular (LV) systolic dysfunction and heart failure. The aim of this study was to assess the effects of exercise training on myocardial diastolic function in T2D patients without ischemic heart disease....
Article
This work examined whether prediction models based on a 2-km walking test are valid for predicting the Vo2max of middle-aged, healthy, moderately to highly physically active adults. Sixty-seven 35- to 45-year-old moderately active men and women and 44 35- to 55-year-old healthy men who participated regularly in marathon-long sports competitions wer...
Article
Sixty-eight previously sedentary volunteers (38 men and 30 women) were randomly divided into active and control groups and subjected to a 10-week programme of walking or cycling while commuting to and from work. The active commuters and the controls complied with the programme on 75–78% and 92% of the workdays, respectively. The mean walking distan...
Article
The health-related physical activity of Finns was studied during the 1980s by analysing changes in activity in a 10-year follow-up of a representative population cohort aged 20–65 years at the onset of the study. The proportion of apparently healthy people exercising at least twice a week for fitness and health increased from about 40% to over 50%....
Article
A 2-km walking test was developed previously to predict maximal oxygen uptake (Vo2max) in field conditions. The prediction is based on the time required for the 2-km fast walk, heart rate at the end of the walk, age and body mass index. This study examined the effects of the walking speed on the prediction of Vo2max in 111 moderately to highly acti...
Article
Forty-nine previously sedentary women, mean age 30 ± 91 years, participated in this study of the relative importance of strength training resistance. The total work was the same in each group, but the work intensity (85%, 50% and 25% of one repetition maximum, 1-RM) and number of sets (3 sets × 5 repetitions, 5 sets × 5 repetitions and 10 sets × 5...
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Unlabelled: This epidemiologic study determined the trend in the number and incidence (per 100,000 persons) of hip fracture among older adults in Finland, an EU country with a well-defined white population of 5.2 million, between 1970 and 2004. The results show that the alarming rise in the fracture incidence from early 1970s until late 1990s has...
Article
The aim of this study was to evaluate myocardial function using pulsed and color-coded tissue Doppler imaging (TDI) and vascular wall elasticity using whole-body impedance cardiography (ICG) in patients with newly diagnosed Type 2 diabetes mellitus (DM2), and to compare the measurements with those of healthy controls. Systolic (SBP) and diastolic (...
Article
Leukocytosis is known to predict future cardiovascular events even in subjects without coronary heart disease (CHD), but its association with early atherosclerotic changes has remained less certain. The aim of the present study was to investigate how the blood leukocyte count compares with several other risk factors for CHD in determining carotid a...
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Full-text available
Menopause may induce a phase of rapid decreases in bone mineral density, aerobic fitness, muscle strength, and balance, especially in sedentary women. The purpose of this study was to examine the effects and feasibility of an exercise program of 1 or 2 bouts of walking and resistance training on lower-extremity muscle strength (the force-generating...
Article
The authors investigated the associations of the amount, frequency and intensity, and type of leisure-time physical activity (LTPA) with the risk of self-reported difficulty in walking (WD) and stair climbing (SCD) over 16 years in a population-based cohort age 40-64 years at the onset of the study. Their results indicated that the risk for SCD was...
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Full-text available
Bone fragility and decreased functional performance are risk factors for osteoporotic fractures. The influence of long-term recreational gymnastics on the maintenance of bone rigidity and physical performance was evaluated. One hundred and seven gymnasts and 110 referents (93% of the original sample) participated in this 6-year prospective study. A...
Article
In the period of 30 years, i.e. from 1973 to 2002, we noticed in Croatia 6 sudden and unexpected cardiac deaths in male athletes during or after training. Two were soccer players, 2 athletic runners, one was a rugby player and one was a basketball player. All of them were without cardiovascular symptoms. At the forensic autopsy, the first athlete,...
Article
Unlabelled: We studied clinical performance of serum TRACP 5b and other bone turnover markers, including S-CTX, U-DPD, S-PINP, S-BALP, and S-OC, for monitoring alendronate treatment. TRACP 5b had higher clinical sensitivity, area under the ROC curve, and signal-to-noise ratio than the other markers. Introduction: The purpose of this study was to...
Article
Leisure time physical activity (LTPA) has been found to prevent several diseases, but little is known about its protective effect against decline in perceived health. The purpose of the present study is to analyze the protective effect of LTPA against the risk of decline in perceived health in a cohort of 19- to 63-year-old Finnish men (n = 1205) a...
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Full-text available
This prospective study set out to determine factors that underlie changes in bone characteristics and physical performance during postmenopausal years. Of 101 peri-menopausal women that originally participated in a randomized, controlled exercise intervention trial, 80 attended the follow-up measurements 9 years later. At follow-up, bone mineral co...
Article
Apolipoprotein E (ApoE) is known to modulate lipoprotein transport and metabolism. The common APOE epsilon2/epsilon3/epsilon4 polymorphism explains part of the variation in plasma cholesterol levels. Polymorphisms of the APOE gene regulatory region are suggested to be involved in explaining variation of lipoprotein levels within the APOE epsilon2/e...
Article
The purpose of this study was to evaluate the remaining effects of 12-month intervention of alendronate and exercise on selected risk factors of fragility fractures in 15-month follow-up after withdrawal of intervention among early postmenopausal women. The trial consisted four experimental groups: (1) 5 mg of alendronate daily + exercise (Al+Ex+),...
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Full-text available
Five sudden cardiac deaths in male adolescents (age 14-18 years) were detected in a 5-year period in Croatia. Two of them had been engaged in physical exercise at school, one as a professional soccer player, one in recreational swimming, and the fifth had just finished secondary school and was working at the site. All of them were autopsied and in...
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This article describes the development of sports and physical activity policies and programs in Finland during the past 30 years. The past two decades have been marked by a shift in emphasis from competitive and elite sports to health-enhancing physical activity for all, as seen most clearly in two successive sports acts and a government resolution...
Article
The purpose of this study was to get reliable insight into injury risk in various commuting and lifestyle activities, as well as recreational and competitive sports. A cohort of 3 657 persons was randomly selected from the 15- to 74-year-old Finnish population. Ninety-two percent (n = 3 363) of the subjects accepted to participate the one-year foll...
Article
Circulating oxidized low-density lipoprotein (oxLDL) has been suggested to play an important role in atherosclerosis development. According to previous observations, oxLDL correlates with clinically manifest coronary and carotid artery disease. We investigated the association between the oxLDL concentration measured directly in plasma and common ca...
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Full-text available
Exercise is recommended to enhance bone health but data on the maintenance of the exercise-induced bone benefit is sparse. The purpose of the study was to assess the maintenance of the musculoskeletal benefits obtained in an 18-month intervention of high-impact exercise in premenopausal women (34 former trainees and 31 controls). Physical performan...
Article
Uvod Čvrsti znanstveni dokazi pokazuju da su mnoge bolesti ili prekursori bolesti češći u osoba koje se rijetko ili uopće ne bave tjelesnom aktivnošću nego kod redovito fizički aktivnih osoba. Broj bolesti ili stanja koje potiče tjelesna neaktivnost posljednjih je desetljeća kontinuirano rastao. Tjelesna je aktivnost bila i ostaje neizostavan biolo...
Article
We studied the fractionization of walking training and searched for the minimum dose to affect coronary risk factors in two randomized controlled trials. Altogether 134 (Study I) and 121 (Study II) healthy, sedentary postmenopausal women started the trials, and 130 (Study I) and 116 (Study II) completed them. In Study I the exercise intensity was 6...
Article
In this randomized, double-blind, placebo-controlled 12-month trial we evaluated effects of weight- bearing jumping exercise and oral alendronate, alone or in combination, on the mass and structure of bone, risk factors for falling (muscle strength and power, postural sway, and dynamic balance), and cardiorespiratory fitness in postmenopausal women...
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Full-text available
Type 2 diabetes is a strong risk factor for coronary heart disease and sudden cardiac death. It is associated with reduced baroreflex sensitivity (BRS) and heart rate variability (HRV), which are indicators of increased risk for mortality and morbidity in various patient populations. This study was designed to assess the effects of exercise trainin...
Article
The purpose of this cohort study was to focus on factors associated with bone mass and structure of lower limbs and physical performance after menopause. Eighty nonsmoking women with a mean age of 62.1 (SD 0.8) years participated in the study. They were classified into two groups by their use of hormone replacement therapy (HRT), either the current...
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Full-text available
Recent animal studies have given evidence that vibration loading may be an efficient and safe way to improve mass and mechanical competence of bone, thus providing great potential for preventing and treating osteoporosis. Randomized controlled trials on the safety and efficacy of the vibration on human skeleton are, however, lacking. This randomize...
Article
The objective of this study is to assess the impact on insomnia symptoms of somatic diseases, psychological factors, living habits and life events during the previous year. Although health problems are a significant cause of insomnia, psychosocial factors are considered to be even more important. The relative impact of these and other factors on in...
Article
Bone characteristics of the humeral shaft and distal radius were measured from 64 female tennis and squash players and their 27 age-, height-, and weight-matched controls with peripheral quantitative tomography (pQCT) and dual energy X-ray absorptiometry (DXA). The players were divided into two groups according to the starting age of their tennis o...
Article
To investigate age, period, and cohort effects on functional status. A prospective cohort study with measurements in 1981, 1990, and 1996. Three municipalities in north east Finland. A regionally representative sample of 19 to 63 year old men and women was drawn from the census data in 1979, of which 758 men and 1033 women initially aged 39-63 year...
Article
The skeletal response to exercise and training on bone is exceptionally good during the growing years. However, it is not known whether the benefit of training on bone is maintained after the training. This 20-month follow-up study assessed the effect of a 9-month jumping intervention on bone gain and physical performance in 99 girls (mean age 12.5...
Article
Full-text available
This randomized controlled study was designed to investigate the effects of a 4-month whole body vibration-intervention on muscle performance and body balance in young, healthy, nonathletic adults. Fifty-six volunteers (21 men and 35 women, aged 19-38 yr) were randomized to either the vibration group or control group. The vibration-intervention con...
Chapter
Human survival and physical performance depend to a large extent on locomotion. The bony skeleton provides a sturdy framework for other locomotive organs and functions. To provide this framework, bones should be strong enough to resist both ordinary and exceptional forces imposed on them, but at the same time weigh as little as possible. The requir...
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Full-text available
The American College of Sports Medicine recommends 20-60 minutes of aerobic exercise three to five days a week at an intensity of 40/50-85% of maximal aerobic power (VO(2)MAX) reserve, expending a total of 700-2000 kcal (2.93-8.36 MJ) a week to improve aerobic power and body composition. To ascertain the minimum effective dose of exercise. Voluntar...
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Full-text available
Physical training may be able to improve bone strength through site-specific changes in the composition, size and structure of the bone without notable increases in volumetric density. To address this possibility specifically, we compared 14 competitive female weightlifters with 14 female physical therapy students. Peripheral quantitative computed...
Article
To evaluate the feasibility and health-related content validity of 6 health-related fitness (HRF) and 3 functional performance (FP) tests among middle-aged and older persons. Cross-sectional methodologic study. Field laboratories in 3 communities of northeast Finland. A regionally representative, community-based cohort of 55- to 79-year-old men (n=...
Article
We compared the effects of one vs two daily bouts of walking on aerobic fitness and body composition in postmenopausal women. One hundred and thirty-four subjects were randomized into exercise groups or a control group and 130 completed the study. The subjects walked 5 d/week for 15 weeks at 65% of their maximal aerobic power expending 300 kcal (12...