About
28
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Introduction
Dr Ijeoma Uzoma research is in Immunology, hematology, cancer genetics, and Bioinformatics. She is a qualified Medical Scientist (BMLS) with an MSc (Haematology); a Certificate in Business Management and a PhD in Cell Biology and Genetics.
Additional affiliations
October 2015 - present
Publications
Publications (28)
Background
The present study aimed to classify lymphoid neoplasms according to the latest World Health Organization (WHO) classification and outlining the distribution in Nigeria of different entities. Additionally, the study describes the prevalence of lymphoid neoplasms associated with Epstein-Barr virus (EBV) infection in the Nigerian population...
Background:
Coronaviruses are a group of viruses that belong to the Family Coronaviridae, genus Betacoronavirus. In December 2019, a new coronavirus disease (COVID-19) characterized by severe respiratory symptoms was discovered. The causative pathogen was a novel coronavirus known as 2019-nCoV and later as SARS-CoV-2. Within two months of its disc...
Background
Integrity of nucleic acids derived from archived formalin-fixed paraffin-embedded (FFPE) cancer specimens affects diagnosis, prognosis, and therapy. Several factors affect the quality and quantity of extracted nucleic acids and one of such factors is storage period.
Aim
We investigated the impact of storage duration on the quality and q...
Science is crucial for evidence-based decision-making. Public trust in scientists can help decision makers act on the basis of the best available evidence, especially during crises. However, in recent years the epistemic authority of science has been challenged, causing concerns about low public trust in scientists. We interrogated these concerns w...
Science is integral to society because it can inform individual, government, corporate, and civil society decision-making on issues such as public health, new technologies or climate change. Yet, public distrust and populist sentiment challenge the relationship between science and society. To help researchers analyse the science-society nexus acros...
The co-occurrence of human immunodeficiency virus and malaria presents a complex medical scenario, significantly impacting the quality of life for affected individuals. This comprehensive review synthesizes current knowledge, challenges, and strategies concerning the concurrent management of these infections to improve overall well-being. Epidemiol...
Scientific information is crucial for evidence-based decision-making. Public trust in science can help decision-makers act based on the best available evidence, especially during crises such as climate change or the COVID-19 pandemic 1,2. However, in recent years the epistemic authority of science has been challenged, causing concerns about low pub...
Background:
Therapy-related acute myeloid leukemia (t-AML) is a well-recognized clinical syndrome occurring in a significant fraction of patients who have undergone previous chemotherapy for a solid tumour.
Objectives:
We aim to evaluate the effect of aqueous extract of fresh Allium sativum cloves on haematological parameters, bone marrow and DN...
Background:
Length at birth is important for evaluating childhood growth and development. It is of interest in Pediatrics because of its implications for perinatal and postnatal morbidity and mortality. Predicting birth length will be useful in anticipating and managing possible complications associated with pregnancy and birth of babies with abno...
Background
The incidence of allergy among mill workers has been a public health concern over
the years. The human allergen-specific immunoglobulin G (IgG) and the total
immunoglobulin E (IgE) are markers for allergic disorders and are important in
health monitoring of individuals exposed to allergens. Nonadherence to health and
safety precautions b...
BACKGROUND: Sickle cell anaemia (SCA, HbSS) is a genetic
disorder of haemoglobin with marked variation in clinical
manifestation. The aim of this study was to determine the foetal
haemoglobin (HbF) status of patients with HbSS, compared with
that of individuals with HbAS and HbAA control as well as to
establish the relationship between HbF level an...
Background
Coronaviruses are a group of viruses that belong to the Family Coronaviridae, Genus Betacoronavirus . In December 2019, a new coronavirus disease (COVID-19) characterized by severe respiratory symptoms was discovered. The causative pathogen was a novel coronavirus known as 2019-nCoV and later as SARS-CoV-2. Within two months of its disco...
Aim: To evaluate the interleukin 3 levels in some Hepatitis B virus and Human immunodeficiency virus (HIV) positive subjects. Study Design: Cross sectional study. Place and Duration of Study: Haematology Department, University of Nigeria Teaching Hospital Enugu, Nigeria, between June and September, 2019. Methodology: A total of 86 subjects were rec...
The presence of BCR-ABL1 fusion gene resulting from a t(9; 22) reciprocal chromosome translocation is the molecular hallmark of chronic myeloid leukemia (CML). In the diagnosis and treatment of CML, peripheral blood or bone marrow samples are usually taken for analysis. However, both methods are invasive sample collection methods, thus a noninvasiv...
Background: The presence of BCR‑ABL1 fusion gene resulting from a t(9; 22)
reciprocal chromosome translocation is the molecular hallmark of chronic myeloid
leukemia (CML). In the diagnosis and treatment of CML, peripheral blood or
bone marrow samples are usually taken for analysis. However, both methods are
invasive sample collection methods, thus...
Aim: The aim of this study was to evaluate the effect of chronic occupational exposure to petroleum products on Hematological indices and liver biochemical profile among petrol station attendants in Enugu, Nigeria.
Subjects and Methods: Ninety participants in Enugu metropolis were recruited comprising of 30 control group (shopkeepers), thirty (30)...
Background: BCR-ABL1 fusion gene is the molecular hallmark of most cases of chronic myeloid leukaemia and some cases of acute lymphoblastic leukaemia. All CML cases that have Philadelphia chromosome, t (9; 22) (q34; q11) translocation express BCR-ABL1. For both diagnosis and minimal residual disease monitoring, Real Time PCR is used to quantify BCR...
Objective:
To measure the transcript levels of Aurora kinases and compare them to their immunoreactivity patterns in prostate tumors.
Materials and methods:
A total of 26 cases of prostate cancer (PCa) and 38 cases of benign nodular hyperplasia (BPH) were sampled from archived formalin-fixed paraffin-embedded tissues. Tissue sections were lysed,...
Questions
Question (1)
I wish to know how to compare mean age of different types of lymphoid neoplasms classified in a study.
