Igor Ponomarev

Russian Academy of Sciences | RAS · Department of Quantum Radiophysics

Introduction: Sebaceous nevus (SN) is a benign skin hamartoma with a potent transformation into benign or malignant tumors in adolescents or adults. Due to the most common location in the esthetic zone, an SN makes patients seek a dermatologist for cosmetic concerns on the face or neck. The surgical excision of a large-sized SN in the esthetic zone...

Introduction: Many clinical studies and protocols have been written about laser treatment for fair skin phototypes. However, for dark-skinned phototypes, information is limited, and the risk of burns is higher, especially if the same settings are recommended for fair skin. Competitive epidermal melanin absorption decreases the light energy reaching...

Background: This study aimed to develop the algorithm for choosing both effective and safe mode of dual-wavelengths copper vapor laser (CVL) photodestruction of dilated dermal vessels in PWS for different skin phototypes. This study is expected to assess the safe parameters for CVL treatment. Methods: We used the multilayered skin model with diffe...

Introduction. Speckled lentiginous nevus or Nevus Spilus (NS) is a congenital or acquired melanocytic nevus. NS appears as dark hyperpigmented macules or papules interspersed in the lentigo-like hyperpigmentation patch. Surgical methods for removing NS, primarily on the skin with a thin dermis, are associated with the risk of disruption of its stru...

Introduction: Surgical methods for removing eyelid nevus are associated with a risk of developing such side effects as scarring or loss of eyelashes. Although current laser modalities have shown promising results, eyelid laser surgery may cause skin discoloration and noticeable scarring. This study aims at evaluating the efficacy and safety of the...

Background. Pyogenic granuloma (PG) or lobular capillary hemangioma, ICD10 code: L98.0. appears as a single bright red or violet papule up to 20 mm in size, on the face, fingers, skull surface, arms, and intergluteal fold, as well as on the oral mucous membranes. Surgical removal of facial PG is not always possible due to insufficient thickness of...

Background. Granulomas of the vermilion border of the lips (GVBL); as a complication of lip tattooing; inevitably poses cosmetic problems. Surgical excision and cryodestruction are associated with an increased risk of scarring and recurrence of GVBL. Laser therapy can selectively destroy a pigment and achieve the desired cosmetic result with minima...

Introduction: Congenital melanocytic nevus (CMN) is a severe challenge for dermatology. This pigmented skin lesion is undesirable for patients because of its localization in open areas of the body. Various visible and near-infrared laser systems and intense pulsed light (IPL) sources have been applied for CMN treatment. However, post-traumatic hype...

Acquired melanocytic nevi in aesthetically significant areas, especially palpebral nevi (PN), are becoming a frequent reason for patients to seek dermatologists. Surgical methods for removal of PN are reported to be associated with the risk of such side effects as scars and loss of eyelashes. Aim of the study. To evaluate the efficacy of the remova...

Acquired melanocytic nevi in aesthetically significant areas, especially palpebral nevi (PN), are becoming a frequent reason for patients to seek dermatologists. Surgical methods for removal of PN are reported to be associated with the risk of such side effects as scars and loss of eyelashes. Aim of the study. To evaluate the efficacy of the remov...

Introduction. Clinical variants of congenital melanocytosis in the dermis- nevus of Ota and nevus of Ito (NOI) - may cause marked cosmetic effects; they fail to regress and are reported to be associated with the risk of malignancy. Purpose. To develop criteria and the algorithm for selecting the optimal laser system and radiation specifications to...

Introduction. Nevus sebaceous of Jadassohn (synonym: nevus of the sebaceous glands) (NSG) presents the congenital malformation of the skin with possible transformation into benign or malignant tumors during the adolescence or adulthood. Commonly appeared on the scalp or neck NSG is frequently concern with cosmetic problems making patients look for...

Introduction.Congenital melanocytic nevus (CMN) is detected at birth or shortly after birth in 1% of infants. The localization of CMN in aesthetically significant areas causes a decline in child self-esteem and causes concern for his parents. Surgical excision of skin areas with CMN is associated with an increased risk of cosmetic side effects and...

Congenital dermal melanocytosis (CDM) is a malformation of the dermis caused by antenatal impairment of melanogenesis. There are considered data on the epidemiology, history of the study, the characteristics of the pathogenesis and clinical picture of CDM. Data on the efficacy and side effects of treatment of CDM with ruby, alexandrite and neodymiu...

The use of a copper vapor laser (CVL) for the treatment of basal cell cancer (BCC) has allowed achieving highly effective elimination of BCC malignant cells without any recurrence for a long time after the procedure. According to recent translational medicine studies, the pathogenetic treatment of malignant skin diseases should include eliminating...

In young children, benign vascular tumors (VT) are most often manifested as congenital hemangioma and infantile hemangioma. There are considered clinical variants, pathogenesis, evaluation of severity and approaches to assessing the effectiveness of laser surgical treatment for VT in infants. For the first time, there are presented numerical criter...

Aim: to assess the efficacy and side-effect risk of the surgical treatment of seborrheic k eratosis (SK) using a copper vapour laser (CVL). Patients and methods. 3980 patients (1214 men and 2766 women aged 20 to 78 years) suffering from SK were treated using a CVL (Yakhroma-Med model, Russian producer) equipped with a laser pen and a scanning nozzl...

Introduction: Basal cell carcinoma (BCC) is the most prevalent form of non-melanoma skin cancer commonly arising in elderly patients. Currently, many laser systems are applied for the treatment of BCC. However, up to the present, there have been several reports concerning ocular side effects due to the laser procedure in the borders of the periorbi...

There are presented data on the epidemiology, pathogenesis, and diagnosis of cutaneous simple capillary malformations, described as Nevus simplex and Nevus flammeus (NF) in the Classification of Vascular Anomalies in a revision on May 2108. There are compared the efficacy and side effects of an application of laser irradiation of different waveleng...

An increase in life expectancy in developed countries is inevitably accompanied by an increase in the number of nonmelanoma skin diseases, which are primarily represented by basal cell cancer (BCC) occurring in elderly and old-age patients. The pathogenesis of such diseases is associated both with impaired proliferation and differentiation of the k...

Numerical simulation was used to select the most efficient, safe and secure scanner operating modes when treating port-wine stains with a copper vapor laser. Scanner operating modes for selective heating of dysplastic vessels in port-wine stains were determined.

Introduction: Rhinophyma is recognized as a common and severe skin disease manifested as progressive thickening of the nasal skin due to hypertrophy of the soft tissue. The most severe complication of rhinophyma is telangiectasis. So far the pathogenetic approach for the treatment of rhinophyma should be based on the removal of the dysplastic vesse...

Background. Rhinophyma is considered to be the most severe stage of rosacea, associated with the proliferation of the nose skin epithelium, hyperproduction of the sebaceous glands and telangiectasia. The treatment of rhinophyma remains a difficult task. One of the problems associated with rhinophyma is thickened and lumpy skin, penetrated with tela...

Introduction: Different yellow lasers have been successfully used for the treatment of vascular lesions. This study is aimed to ascertain the role and efficiency of copper vapor lasers (CVLs) and pulsed dye lasers (PDLs) for the treatment of vascular lesions using numerical modeling and to compare results with our clinical experience. In this study...

Numerical simulation of blood vessel heating is used to select the most efficient and safe methods of laser treatment of “port-wine stains”. Selective heating under radiation is calculated for a 980-nm diode laser, a Nd:YAG laser, a copper vapor laser (CVL), and a pulsed dye laser (PDL). The energy exposure range (fluence), the diameter and depth o...

Aim. Comparison of effectiveness of the application of copper vapor laser (CVL) and pulsed dye laser (PDL) in clinical practice. Development of choice criteria of the more effective method of treatment.Materials and methods. The clinical data using CVL and PDL in the treatment of skin vascular malformations are presented. The treatment gave good re...

A computer simulation technique was employed to study the selective heating of a tissue vessel using emission from a pulsed copper vapor laser and a pulsed dye laser. The depth and size of vessels that could be selectively and safely removed were determined for the lasers under examination.

Цель. Сопоставление эффективности применения лазера на парах меди (ЛПМ) и импульсного лазера на красителе (ИЛК) в клинической практике. Разработка критериев выбора более эффективного метода способа воздействия. Материалы и методы. Приведен клинический опыт применения ЛПМ и ИЛК для лечения сосудистых новообразований кожи у 1242 пациентов, которые бы...

24 года, обратилась в нашу клинику со множественными образованиями в периорбитальной области, вызванными контагиозным моллюском. До этого в течение 6 мес наблюдалась у косметологов с диагнозом «фиброма». Из анамнеза: больна 7 мес. Когда впервые отметила появление одного образования на правом веке, пыталась выдавливать самостоятельно, затем процесс...

We present the experience of application of "Yakhroma-Med" copper vapor laser system for the treatment of venouse lakes (VL) of the vermilion border. The yellow wavelength of the generated laser radiation reaches 578 nm falls at the peak of hemoglobin absorption. The treatment was conducted in 58 patients with VL rising above the skin for no more t...

We present the experience of application of "Yakhroma-Med" copper vapor laser system for the treatment of venouse ectasia (VE) of the vermilion border. The yellow wavelength of the generated laser radiation reaches 578 nm falls at the peak of hemoglobin absorption. The treatment was conducted in 58 patients with VE rising above the skin for no more...

Vascular tumors occupy an important place among the benign tumors. Blood vessels tumors are studied and described in details, while there are few data about tumors of the lymphatic vessels in the literature and there are no methods of therapy. The aim of our work was to study the effectiveness of laser treatment method for patients with skin lympha...

Copper vapor laser medical system YACHROMA-MED laser treatment of benign pigmented skin lesions:selective laser therapy for lymphangioma on a Yachroma-Med medical laser system is highly effective.

The results of medical application of new generation state-of-the-art copper vapor laser for dermatology and cosmetic surgery are discussed. “YAHROMA-Med” is specially designed for the treatment of different pigmented lesions such as lentigo, cafe-au-lait stains, color tattoos

The results of medical application of new generation state-of-the-art copper vapor laser for dermatology and cosmetic surgery are discussed. “YAHROMA-Med” is specially designed for the treatment of different vascular and pigmented lesions such as port wine stains, telangiectasias, hemangiomas, lentigo, cafe-au-lait stains, color tattoos, post surgi...

72 Пациентка Н. (26 лет) обратилась в декабре 2015 г. с жалобами на множе-ственные высыпания на коже лица. Анамнез болезни: впервые высыпания на коже лица появились в возрас-те 14 лет. Лечилась наружными средствами (ретиноиды, азелаиновая кис-лота), но без существенного результата. В течение последнего года стала отмечать ухудшение состояния кожи,...

В статье обсуждаются механизмы лазерного лечения сосудистых дефектов кожи. Проводится сравнение различных систем и импульсных источников света.

The possibility of using copper vapour laser (CVL) for a selective deposition printing viscous inks from an ink carrier (transparent substrate) to an image carrier for non-impact high-definition imaging systems was studied. The CVL radiation was focused by a long focused lens on the boundary between transparent substrate and printing viscous inks....

Topics relating to spectroscopic applications of a new generation of metal vapour lasers are discussed. These lasers are distinguished by a high efficiency, compact size, air cooling, and user friendliness. Practical results are given of an investigation of the Raman scattering of light in gallium phosphide, silicon, graphite, and diamond films dir...

The correct selection of patients is the most difficult part of the laser treatment. Since 1985 the total number of patients treated by us using different laser systems was 1544. High power lasers: Nd:YAG and CO2 lasers were used by us for surgical treatment. Low power lasers: Helium-Neon, Copper vapor, gold vapor and dye lasers were applied by us...

New advances of copper vapor laser (CVL-laser) have been studied. Two wavelength radiation of the laser (511 nm and 578 nm) gives deeper permeability into organic tissues. Besides, the short pulse prevents the warm relaxation of small vessels. The technical data of CVL-laser: operating regime -- pulse, pulse duration -- 20 ns, pulse frequency 15000...

One of the main problems which arise employing PDT is the patient's sensitization to the sunlight during a 4 - 6 week period after the i/v photosensitizers injection. Applying PDT for patients with head and neck cancer there often is the possibility to inject photosensitizer (the doses of photosensitizer used were many times smaller than in ordinar...

Form 1989 to 1994 more than 600 various malignant foci were treated by more than 400 courses of PDT in the Lithuanian Oncology Center. During the application of PDT we used the following lasers: 35 MW He-Ne laser with 630-1 nm wavelength; 100-300 MW dye lasers with a wavelength of 629-3 nm, and a 100- 300 MW gold vapor laser, with a wavelength of 6...

Populations of CuI ground state, resonance, and metastable levels have been measured in CuBr laser with and without hydrogen additives. Temporal evolution and spatial distribution populations have been studied during the excitation pulse and also during the interpulse period of time. Addition of hydrogen results in a smaller rate of resonance and m...

An analysis was made of a method of measuring the ground-state population of copper atoms in the medium of a self-heated copper vapor laser. The active medium was probed using radiation from a pulsed dye laser (temporal resolution 5 ns, spatial resolution 2 mm). An investigation was made of the ground-state kinetics during an excitation pulse and i...

Kinetics of population and depopulation of atomic copper ground state, resonance and metastable levels and also some higher laying levels were measured in active medium of copper vapor laser. A typical commercial sealed-off self-heated discharge tube was studied. Simultaneously at the same conditions of operation characteristics of excitation pulse...

A technique for measuring the population of the copper atom ground state in the medium of a self-heated copper-vapor laser is developed. The pulsed dye laser was used to sound the active medium (the temporal resolution was 5 ns and the spatial resolution was 2 mm). The kinetics of the ground state was studied in the excitation pulse and in the inte...

The kinetics of the active levels of a copper vapor laser excited by pulse pairs was studied experimentally for the first time. It was found that as the delay was reduced, the lasing parameters in the second pulse were mainly limited by the prepulse population of the metastable level.

The kinetics of the excitation of copper-vapor laser working levels in the twin pulse regime is studied experimentally. The populations of the resonance and metastable levels are measured by means of resonant absorption of the active medium of the radiation of the pulsed dye laser. It is shown that the parameters of the laser action in the second p...

An experimental investigation was made of the relaxation of the populations of 2D5/2 and 2D3/2 metastable states of the copper atom in the interpulse period in the active medium of a copper bromide vapor laser under near-optimal lasing conditions. Measurements were resolved over the cross section of the discharge zone. The processes responsible for...

A study was made of the spatial kinetics of the decay of metastable atoms, resolved over the radius of a copper vapor gas discharge tube, under conditions typical of the self-heating regime. The investigations were carried out for a time interval of 1–100μsec after the excitation pulse, with a radial resolution of 2–3 mm, in the entire lasing tempe...

A mean generation of 18 w with a practical effectiveness of 1% is achieved in copper bromide vapor lasers with additions of small quantities of hydrogen (0. 3 mmHG) to the buffer gas (neon). An investigation is performed on the electrical characteristics of the excitation pulses. The mechanism which causes the effect of hydrogen on the generation c...