Ignacio Minguela

• Osakidetza

In recent years, the meaning of adequacy in peritoneal dialysis has changed. We have witnessed a transition from an exclusive achievement of specific objectives -namely solute clearances and ultrafiltration- to a more holistic approach more focused to on the quality of life of these patients. The purpose of this document is to provide recommendatio...

Peritoneal infections still represent a most feared complication of chronic Peritoneal Dialysis, due to their high incidence and relevant clinical consequences, including direct mortality, technique failure and a significant burden for the health system. The practices for prevention and treatment of this complication show a remarkable heterogeneity...

Resumen Las infecciones peritoneales siguen constituyendo una complicación muy relevante de la diálisis peritoneal, por su incidencia todavía elevada y por sus importantes consecuencias clínicas, en términos de mortalidad, fracaso de la técnica y costes para el sistema sanitario. Las prácticas de prevención y tratamiento de esta complicación muestr...

In the last years there is a growing relationship between uric acid and cardiovascular diseases and chronic kidney disease. There are several epidemiologic studies that find out an association between uric acid and the future developing of chronic kidney disease, higher rate of loss of kidney function, higher blood pressure, cardiovascular events,...

AimThe aim of this study was to evaluate the use, safety and efficacy of intravenous iron administration in the nephrology outpatient consulting room in patients not under dialysis.

Patients suffering chronic illnesses, such as those on replacement therapy, condition and are conditioned by their family, work, and social environment. A continuous psychophysical impairment occurs and alters the hormonal stress mediators from the central nervous system and the hypothalamic-pituitary-adrenal axis. Such stress situation causes a pa...

Introducción El sangrado glomerular importante puede originar un fracaso renal agudo y está en discusión si se debe a la obstrucción de las luces tubulares o a necrosis tubular aguda por toxicidad de los productos de degradación de la hemoglobina. Caso clínico Mujer de 87 años que acudió a urgencias de otro centro por anuria de 4 días de evolución...

Introducción La disfunción del catéter de diálisis peritoneal se puede originar por desplazamientos fuera del área pelviana, obstrucciones de la luz del catéter por coágulos o atrapamiento por epiplón, y solucionarlo puede requerir cirugía. Caso Mujer de 58 de edad en diálisis peritoneal (DP) continua ambulatoria desde 6 meses antes. Acude a la un...

We review the treatment of renal anemia with intravenous iron sucrose in predialysis, hemodialysis and peritoneal dialysis patients. The available evidence shows that intravenous iron sucrose is a highly effective treatment for iron-deficiency anemia in patients with renal disease.Moreover, intravenous iron sucrose is a cost-effective treatment bec...

To evaluate catheter-related complications among self-locating and other variants of Tenckhoff catheters. We studied all self-locating catheters implanted in our hospitals from May/97 to Dec/05. We extended the follow-up to Jun/05. We collected demographic data, causes of catheter withdrawal and dropping of PD. We studied data about technique and c...

We analyzed malfunction rates (obstruction, omental wrapping, displacement) and catheter survival for self-locating catheters as compared with other Tenckhoff catheter designs. We conducted our survey at two centers, prospectively studying all self-locating catheters implanted from May 1997 to October 2000 and used for peritoneal dialysis (PD). Ten...

Intraocular pressure (IOP) may rise during hemodialysis sessions in predisposed patients because of a rapid drop in osmolality at the blood compartment. A patient with diabetes had painful ocular episodes during hemodialysis that were associated with an IOP increase. We modified the dialysis parameters to prevent a rapid decrease in osmolality by c...

The Fanconi syndrome is an array of multiple proximal renal tubular dysfunctions occurring in association with several exogenous toxins, such as aminoglycosides. These antibiotics remain the drugs of choice in most gram-negative infections, but nephrotoxicity is the main drawback for them. Furthermore, the nephrotoxic effects may be overlooked with...

We studied 142 consecutive percutaneous renal biopsies (puncturing on 73 allografts and 69 native kidneys) which were performed under continuous ultrasonic guidance, on 133 adult patients. The patients were monitored, at least, during the next 24 hours. We compared the complication rate for biopsies recording clinical and biochemical data and, the...

Patients suffering chronic illnesses, such as those on replace-ment therapy, condition and are conditioned by their family, work, and social environment. A continuous psychophysical im-pairment occurs and alters the hormonal stress mediators from the central nervous system and the hypothalamic-pituitary-adre-nal axis. Such stress situation causes a...

ResumenIdioma El hierro sacarosa es una alternativa terapéutica eficaz y bien tolerada en el tratamiento y la prevención de la anemia por déficit de hierro, tanto por sí solo como combinado con terapias de agentes estimulantes de la eritropoyesis (ESA), por ejemplo, con rHvEPO. La administración intravenosa del hierro sacarosa es más eficaz y rápid...