Ibrahim Demirkan

Afyon Kocatepe University | AKU · Department of Veterinary Surgery

Morphology and Volume Measurement of Bursa Fabricius by Stereology in Merlin (Falco Columbarius) ABSTRACT Bursa fabricius (Bursa cloacalis or Bursa fabricii) is a lymphoepithelial organ of poultry and serves as the primary lymphoid organ. In addition to the development and differentiation of Bursa Fabricius B lymphocytes, immunoglobulin is also res...

The treatment of cancer is highly challenging and contains surgery, chemotherapy and radiotherapy alone or combinations which have various side effects on the patient health. This study aimed at observing the possible antineoplastic activity of AK27-herbal mixture, a combination of pistachio resin, rhus resin, pollen, Nigella sativa seed, pomegrana...

The aim of this study was to evaluate the efect of dexketoprofen trometamol (DEX) on acute cortisol, infammatory response and oxidative stress following hot-iron disbudding in calves. Twelve male Holstein Friesian dairy calves, weighing between 52 and 82 kg and 6-8 weeks of age were used for disbudding procedure. While calves (n = 6) in DEX group w...

Increase in intra-abdominal pressure may affect gastric emptying time but the precise effect has not been demonstrated. Effects of acute increase of intra-abdominal pressure on gastric emptying time can not be demonstrated in clinical or experimental studies. In this study we aimed to study the effect of increased intra-abdominal pressure on gastri...

The purpose of this study was to describe arteries supplying the ovaries and uterus in the chinchilla. Five healthy adult female chinchillas were used. In order to reveal the arterial network by dissecting under a stereoscopic microscope, latex coloured with red ink was injected through the common carotid artery. The ovaries of the chinchilla are s...

Bovine digital dermatitis (BDD) is an epidermitis which is a leading cause of infectious lameness. The only recognized diagnostic test is foot inspection, which is a labour-intensive procedure. There is no universally recognized, standardized lesion scoring system. As small lesions are easily missed, foot inspection has limited diagnostic sensitivi...

Bovine digital dermatitis (BDD) is a debilitating infection that is being increasingly recognized in livestock worldwide. Several treponeme phylotypes have been identified in BDD lesions, although only a single BDD-associated treponeme taxon (Treponema brennaborense) has been proposed thus far. In a previous study, we observed that four BDD-associa...

This study used a PCR-based approach targeting 16S rRNA gene fragments to determine the occurrence and association of the three bovine digital dermatitis (BDD) treponeme phylogroups within lesions found in cattle from the United Kingdom. Examination of 51 BDD lesions collected from infected cattle across the United Kingdom revealed that BDD trepone...

Bovine digital dermatitis (BDD) is an infectious lameness in cattle, which has a large global impact in terms of animal welfare and cost. The majority of evidence suggests that spirochaetes are the aetiological agent of this disease. The aim of this study was to identify the susceptibility of BDD associated spirochaetes to a range of antimicrobial...

The aim of this experimental study was to investigate the possible protective effect of dantrolene on neuronal injury induced by aortic ischemia/reperfusion (I/R). Nineteen rabbits were divided into three groups: sham (group 1, n = 5, no I/R), control (group 2, n = 7, only I/R) and dantrolene (group 3, n = 7, dantrolene + I/R). Abdominal aortic occ...

Bovine digital dermatitis (BDD) is a severe infectious cause of lameness which has spread through dairy cattle populations worldwide, causing serious welfare and agricultural problems. Spirochetes are the main organisms implicated and have previously proven difficult to isolate. This study aimed to isolate and characterise the range of spirochetes...

A case of uterine macro abscess associated with unilateral pyometra and cystic endometrial hyperplasia in a 7 year old multiparous Pointer bitch is reported and discussed.

This study aimed to document the detailed features of the hind limb bones in chinchillas (Chinchilla lanigera). Twenty chinchillas (10 females and 10 males) were used. Animals were euthanized and X-ray of appendicular skeleton of pelvis was taken immediately. Then the bones were macerated. The iliac wing was considerably long and the gluteal line f...

This study documents the detailed features of the morphological structure and the innervation areas of the plexus brachialis in the chinchilla (Chinchilla lanigera). The animals (5 female and 5 male) were euthanased with ketamine hydrocloride and xylazine hydrocloride combination, 60 mg/kg and 6 mg/kg, respectively. Skin, muscles and nerves were di...

There are several factors affecting the aggressiveness of animals and human beings, particularly abnormal serum lipid concentrations have been associated with aggression in humans, and were also scarcely reported in aggressive dogs. The possible link between serum lipid concentrations and degrees of aggression in MPD (military patrol dogs) trained...

The aim of the study was to characterize a spirochaete isolated from the lesions of a cow with digital dermatitis (DD). The characterization was on the basis of its light and electron microscopic appearance, enzymic profile and DNA sequence analysis of its flagellin and 16S rRNA genes. The spirochaete was 6-8-microm long and 0.2-0.3 microm in diame...

A potential pathological role for spirochaetes in bovine digital dermatitis (bovine DD) and severe virulent ovine foot rot (SVOFR) has been considered and a treponeme isolate obtained from each disease in the UK. In this work, we have investigated the hypothesis that the two diseases may have a shared (common) spirochaetal aetiology. Experiments we...

In this study, it was aimed to examine the urinary system and to determine normal ultrasonographic appearance by rectal ultrasonography in Holstein cows. The study material consisted of 20 bladders, 20 urethras, and 20 right and 20 left kidneys, in 20 Holstein cows. A portable ultrasonograph combined with a 6 MHz linear rectal probe (transducer) wa...

Bovine digital dermatitis causing lameness in a dairy herd in Turkey is described. The lesions were similar to those described for Mortellaro disease. Inflammation of the skin was mostly located at the plantar aspect of the foot, just above the interdigital cleft, and resembled strawberry-coloured epidermal erosion, which was prone to bleed when vi...

A sloughed hoof in a young bull as a sequela of foot and mouth disease was treated by skin grafting. Skin blocks obtained from the craniolateral thoracic area of the same animal were placed in slit-like pockets created on the coronary band. New hoof formation was completed within 20 weeks.

Twenty young bulls suffering from penile tumors were treated by the removal of neoplastic tissues either by electrocautery or scalpel excision and the results were compared. It was observed that electrocautery appeared to be superior to the scalpel excision in young bulls and it can be used clinically.

To evaluate the effectiveness of transposition of the sacrotuberous ligament (LST) for the treatment of coxofemoral luxation in the dog. In vivo experimental study. Ten mixed-breed dogs (weighing 12 to 26 kg). After general anesthesia, the LST was exposed and released from the sacrum with a sacral bone fragment. Coxofemoral luxation was created by...

Digital dermatitis, presenting as a focal necrotic dermatitis on the skin of cows' feet adjacent to the interdigital space, has been associated with dermal infection by spirochaetes. Lesions cause severe, transient lameness. An enzyme-linked immunoassay (ELISA) was used to measure IgG(2) antibody titres against three different spirochaetes: USA bov...

A novel spirochaete was isolated from a case of severe virulent ovine foot rot (SVOFR) by immunomagnetic separation with beads coated with polyclonal anti-treponemal antisera and prolonged anaerobic broth culture. The as yet unnamed treponeme differs considerably from the only other spirochaete isolated from ovine foot rot as regards morphology, en...

A potentially infectious aetiology for digital dermatitis in dairy cattle was investigated and centred on the possible involvement of spirochaetes. An enzyme-linked immunosorbent assay (ELISA) was developed to detect bovine anti-Borrelia burgdorferi (B31) and anti-Treponeme (USA bovine isolates) antibodies in the sera of cows; sera were further tes...

A study was carried out to determine whether spirochaetes are frequently associated with digital dermatitis in United Kingdom (UK) dairy cattle. Histopathological examination of lesions using a silver stain showed a large number of unidentified spirochaete-like organisms present in digital dermatitis hoof skin tissue in all examined biopsies. Immun...