How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
Citations since 2016
11 Research Items
Designing and improving chemical analysis instrumentation from a chemometric perspective. Working as part of a team to break the sub-cellular mass spectrometry imaging barrier.
January 2016 - November 2019
- Teacher of Record
- • Analyzed samples provided to the Mass Spectrometry Center • Trained users on liquid chromatography and mass spectrometry • Developed and taught laboratory lessons on de novo peptide sequencing
For wide class characterizations of volatile organic compounds (VOCs), conventional gas chromatography mass spectrometry (GC-MS)-based techniques are utilized. These GC-MS-based chemical identification approaches typically rely on library searches against ion fragmentation patterns of known compounds. Although MS library searches can often provide...
Mass spectrometry imaging (MSI) maps the spatial distributions of chemicals on surfaces. MSI requires improvements in throughput and spatial resolution, and often one is compromised for the other. In microprobe-mode MSI, improvements in spatial resolution increase the imaging time quadratically, thus limiting the use of high spatial resolution MSI...
Radical resection for patients with oral cavity cancer remains challenging. Rapid evaporative ionization mass spectrometry (REIMS) of electrosurgical vapors has been reported for real-time classification of normal and tumor tissues for numerous surgical applications. However, the infiltrative pattern of invasion of oral squamous cell carcinomas (OS...
Time‐of‐flight (TOF) systems are one of the most widely used mass analyzers in native mass spectrometry (nMS) for the analysis of non‐covalent multiply charged bio‐macromolecular assemblies (MMAs). Typically, microchannel plates (MCPs) are employed for high mass native ion detection in TOF MS. MCPs are well known for their reduced detection efficie...
): Comprehensive characterization and structural elucidation of specific chemical sub-classes within a complex mixture often require analyte separation, a variety of spectroscopic techniques, and inquiry into reactivity patterns. Crude oil is one of the most challenging and highly complex mixtures and, for classification purposes, it is typically s...
Chemical identification often relies on matching measured chemical properties and/or spectral “fingerprints” of unknowns against their precompiled libraries. Chromatography, absorption spectroscopy, and mass spectrometry are all among analytical approaches that provide chemical measurement databases amenable to library searching. Occasionally, usin...
Objective: β-Aminoisobutyric acid (BAIBA) has shown to modulate uncoupling protein (UCP)-1 expression, which is mainly expressed in white adipose tissue; however, no studies to date have analyzed its potential effect on the main uncoupling protein of skeletal muscle, UCP-3. The main goal of this study was to assess the potential effect of acute aer...