I-Te Wang

Taipei Medical University Hospital | TMUH · Department of Obstetrics and Gynecology

Overactive bladder (OAB) and interstitial cystitis/painful bladder syndrome (IC/PBS) are 2 lower urinary tract disorders with urgency and bladder pain for diagnosis and with several other shared symptoms. Because of their overlapping symptoms, precise differential diagnosis of OAB and IC/PBS remains difficult. Thus, we characterize a subgroup of OA...

Objective To assess the association between antipsychotic use in early pregnancy and the risk of maternal and neonatal metabolic complications. Methods We conducted a population-based retrospective cohort study (January 1, 2010, to December 31, 2016) using the Health and Welfare Database in Taiwan. Pregnant women (18 to 49 years of age) were group...

Objectives: To compare the survival outcomes between minimally invasive surgery (MIS) and laparotomy radical hysterectomy in patients with early-stage cervical cancer. Methods: We conducted a retrospective study involving women who received a radical hysterectomy for cervical cancer, stage IA1 with lymphovascular invasion, IA2, IB1, IB2, or IIA...

In 2013, the U.S. Food and Drug Administration issued a safety warning that cautioned against using magnesium sulfate (MgSO4) injections for more than 5 to 7 days to stop preterm delivery due to the bone problems subsequently observed in infants. However, the warning was mainly based on case reports, and further investigation is necessary to determ...

Cold atmospheric plasma (CAP) is a promising tool to overcome certain cancerous and precancerous conditions in dermatology. A scheme of transferred CAP was first developed to treat melanoma (B16F10) skin cancer cells as well as non-malignant (L929) cells in vitro. CAP was transferred using a silicone tube with a jet system that was developed and wa...

Background Evidence regarding prenatal antidepressant use and the development of hypertensive disorders during pregnancy is inconsistent. Previous studies have reported that antidepressant use during pregnancy increases the risk of gestational hypertension and preeclampsia, but the results of these studies are potentially confounded by important me...

A novel device for cholesteric liquid crystal (CLC)-based microfluidic chips, accommodated in a polydimethylsiloxane material, was invented. In this device, the reorientation of the CLCs was consistently influenced by the surface of the four channel walls and adjacent CLCs. When the inside of the microchannel was coated with the alignment layer, th...

The purpose of this study was to evaluate the association between tocolysis for preterm uterine contraction and the risk of nonreassuring fetal status. This was a retrospective cohort study using data from the Taiwan National Health Insurance Research Database. Pregnant women were enrolled if they delivered a baby during January 1, 2003 to December...

Cervical cancer is one of the most common gynecological cancers in association with high mortality and morbidity. The present study was aimed to investigate the in vitro effects of zoledronic acid (ZA) on viability and induction of apoptosis and autophagy as well as inflammatory effects in three human cervical cancer cell lines (HeLa, SiHa, and CaS...

Objectives The safety and efficacy of the RevoLix 2-μ continuous wave laser for hysteroscopic myomectomy (HM) was evaluated. Materials and methods A retrospective study was undertaken to evaluate 13 patients with symptomatic submucous myomas, who were treated with HM using a RevoLix laser application. The evaluation items included blood loss from...

Purpose: We aimed to explore the relationship between physician characteristics and their prescribing behavior regarding category D and X drugs for pregnant women by using a population-based data set in Taiwan. Methods: The sampled population for the study included 14,430 women. These women received a total of 198,420 prescriptions during pregna...

Using 2 nationwide population-based datasets, this study aimed to assess the risk of adverse pregnancy outcomes, including low birthweight (LBW), preterm birth, small for gestational age (SGA), cesarean section (CS), lower Apgar score, and preeclampsia/eclampsia, between women with and without pneumonia. This study included 1462 women who had been...

We examined the risk of adverse pregnancy outcomes, including low birthweight (LBW), preterm birth, small for gestational age (SGA), cesarean section (CS), low Apgar score (at 5 minutes after delivery), and preeclampsia in pregnant women with and without obstructive sleep apnea (OSA). Our subjects included 791 women with OSA and 3955 randomly selec...

This population-based study aimed to compare the risk of postpartum hemorrhage (PPH) for patients who underwent cesarean section delivery (CS) with general vs spinal/epidural anesthesia. We identified 67,328 women who had live singleton births by CS by linking the Taiwan National Health Insurance Research Dataset and the national birth certificate...

To evaluate the therapeutic efficacy of laparoscopic uterine artery occlusion combined with myomectomy through a minilaparotomy in the treatment of recurrent uterine myomas, compared with myomectomy alone. Controlled, nonrandomized clinical study. University-affiliated tertiary care referral center. Eighty-two women with symptomatic, recurrent myom...

Background: Even though cervical cancer is largely considered to be a sexually transmitted disease with a viral etiology, other modes of transmission are theoretically possible. Case: A 38-year-old woman with cervical squamous cell carcinoma adamantly denied having ever had sexual intercourse due to personal, religious and cultural beliefs. Con...

Objective: To evaluate the therapeutic effects of uterine artery ligation for pregnant women with uterine leiomyomas, who are undergoing cesarean section. Design: Prospective clinical study without randomization. Setting: University-affiliated tertiary referral center. Patient(s): Forty-eight women with uterine leiomyomas undergoing cesarean sectio...

Objective: To evaluate the therapeutic effects of uterine artery ligation for pregnant women with uterine leiomyomas, who are undergoing cesarean section. Design: Prospective clinical study without randomization. Setting: University-affiliated tertiary referral center. Patient(s): Forty-eight women with uterine leiomyomas undergoing cesarean...

The physiological changes in endometriosis involving multiple steps of matrix remodeling include abnormal tissue growth, invasion, and adhesion formation. Endometriosis-associated abnormal matrix remodeling is affected by several molecular factors including proteolytic enzymes and their inhibitors, which mediate tissue turnover throughout the repro...