Huseyin Uvet

Yıldız Technical University · Department of Mechatronics Engineering

The efficient mixing of fluids at microscale dimensions presents challenges due to the dominant laminar flow regime which restricts convective mixing. This study introduces a numerical analysis of a novel microrobotic mixing system with a levitated propeller robot, driven by magnetic fields, within a Y-shaped microchannel with a square cross-sectio...

Lumbar disk segmentation is essential for diagnosing and curing spinal disorders by enabling precise detection of disk boundaries in medical imaging. The advent of deep learning has resulted in the development of many segmentation methods, offering differing levels of accuracy and effectiveness. This study assesses the effectiveness of several soph...

Efficient mixing of fluids at microscale dimensions presents challenges due to the dominant laminar flow regime, restricting convective mixing. This study introduces a numerical analysis of a novel microrobotic mixing system with a levitated propeller robot, driven by magnetic fields, within a Y-shaped microchannel with a square cross-section (500x...

This study develops a Convolutional Neural Network (CNN) model for detecting myocardial infarction (MI) from Electrocardiogram (ECG) images. The model, built using the InceptionV3 architecture and optimized through transfer learning, was trained using ECG data obtained from the Ch. Pervaiz Elahi Institute of Cardiology in Pakistan. The dataset incl...

Accurately measuring cell stiffness is challenging due to the invasiveness of traditional methods like atomic force microscopy (AFM) and optical stretching. We introduce a non-invasive off-axis system using holographic imaging and acoustic stimulation. This system features an off-axis Mach-Zehnder interferometer and bulk acoustic waves to capture c...

Precise manipulation of flexible surgical tools is crucial in minimally invasive surgical procedures, necessitating a miniature and flexible robotic probe that can precisely direct the surgical instruments. In this work, we developed a polymer-based robotic fiber with a thermal actuation mechanism by local heating along the sides of a single fiber....

The development of additive manufacturing (AM) technologies has significantly advanced fabrication capabilities, yet achieving optimal surface quality and mechanical properties in end-use products is challenging. The primary objective of this study is to improve specific characteristics of 3D-printed components by employing a chemical post-processi...

Study design: Cross-sectional database study. Objective: The purpose of this study was to develop a successful, reproducible, and reliable convolutional neural network (CNN) model capable of segmentation and classification for grading intervertebral disc degeneration (IVDD), as well as quantify the network's impact on doctors' clinical decision-...

Funding Acknowledgements Type of funding sources: None. Background/Introduction Treadmill Exercise Test (TET) application in terms of detecting Obstructive Coronary Artery Disease is defined to be limited due to low sensitivity and specificity rates. TET results and patients' clinical symptoms influence cardiologists' decision to perform Coronary...

Hydrodynamic cavitation (HC) is a phase change phenomenon, where energy release in a fluid occurs upon the collapse of bubbles, which form due to the low local pressures. During recent years, due to advances in lab-on-a-chip technologies, HC-on-a-chip (HCOC) and its potential applications have attracted considerable interest. Microfluidic devices e...

In this study, we aim to propose a useful course design framework for undergraduate programming languages in hybrid learning environments. Hybrid learning environments are a means of delivering instructional content in that online educational materials and opportunities for interaction were combined with traditional classroom methods. We followed t...

Industry 4.0 and 5.0 topics are emerging fields and have seen rising demand recently. There is a critical need, on the other hand, for improved methods of instructing programming languages since a growing lack of student motivation during the pandemic has had a deleterious influence on the education of programmers. In this context, online/hybrid co...

Technologies that rely on the fundamental principle of thermal expansion have demonstrated high-precision, a growing demand in fields driven by miniaturization. However, scalable production of high aspect ratio devices that harness this capability while facilitating flexibility in design and functionality remains a challenge. We employed the high-t...

The purpose of this research is to create a machine learning-based smart coaching approach for football that can replace manual analysis with real-time feedback for trainers. In-depth analysis of football player data by humans is time-consuming, error-prone, and requires a lot of effort. This exploratory study demonstrates the feasibility of using...

Accurate assessment of cell stiffness distribution is essential due to the critical role of cell mechanobiology in regulation of vital cellular processes like proliferation, adhesion, migration, and motility. Stiffness provides critical information in understanding onset and progress of various diseases, including metastasis and differentiation of...

Introduction TET results and patients' clinical symptoms influence cardiologists' decision to perform Coronary Angiography (CAG) which is an invasive procedure. Since TET has high false positive rates, it can cause an unnecessary invasive CAG. Our primary objective was to develop a machine learning model capable of optimizing TET performance based...

Cell migration is closely associated with various pathological conditions such as tumor invasion and metastasis as well as cell proliferation. The in vitro wound healing assay involves a simple and affordable technique and is used to examine the migration abilities of cells in a wound area created on confluent cell culture. Although this technique...

Dermoscopy is the visual examination of the skin under a polarized or non-polarized light source. By using dermoscopic equipment, many lesion patterns that are invisible under visible light can be clearly distinguished. Thus, more accurate decisions can be made regarding the treatment of skin lesions. The use of images collected from a dermoscope h...

Creating the best possible conditions is essential for proper cell growth. Incubators, a type of biotechnological instrument, are used to simulate this condition and maintain the cells within them. The processes involved in creating a mobile incubator, which are essential for monitoring a cell culture's physiological parameters, are outlined in thi...

Background: The diagnosis of superficial fungal infections is still mostly based on direct microscopic examination with Potassium Hydroxide solution. However, this method can be time consuming and its diagnostic accuracy rates vary widely depending on the clinician's experience. Objectives: This study presents a deep neural network structure tha...

Skin cancer is one of the deadly types of cancer and is common in the world. Recently, there has been a huge jump in the rate of people getting skin cancer. For this reason, the number of studies on skin cancer classification with deep learning are increasing day by day. For the growth of work in this area, the International Skin Imaging Collaborat...

The purpose of this study is to find ideal forces for reducing cell stress in wound healing process by micro robots. Because of this aim, we made two simulations on COMSOL Multiphysics with micro robot to find correct force. As a result of these simulation, we created force curves to obtain the minimum force and friction force that could lift the c...

Objective: Hydrodynamic cavitation is characterized by the formation of bubbles inside a flow due to local reduction of pressure below the saturation vapor pressure. The resulting growth and violent collapse of bubbles lead to a huge amount of released energy. This energy can be implemented in different fields such as heat transfer enhancement, wa...

Clinical dermatology, still relies heavily on manual introspection of fungi within a Potassium Hydroxide (KOH) solution using a brightfield microscope. However, this method takes a long time, is based on the experience of the clinician, and has a low accuracy. With the increase of neural network applications in the field of clinical microscopy it i...

This study investigates the effects of porosity on flying creatures such as dragonflies, moths, hummingbirds, etc. wing and shows that pores can affect wing performance. These studies were performed by 3D porous flapping wing flow analyses on Comsol Multiphysics. In this study, we analyzed different numbers of the porous wing at different angles of...

The importance of an untethered microrobotic platform that can operate on high flow rate microfluidic channels for in-vitro applications is increasing rapidly. This paper presents a method to manipulate a microrobot in a fluidic chip when high flow rates (4 mL/min, 82.304 mm/s) are applied. This method is based on a novel permanent magnet-based dia...

Accurate assessment of stiffness distribution is essential due to the critical role of single cell mechanobiology in the regulation of many vital cellular processes such as proliferation, adhesion, migration, and motility. Cell stiffness is one of the fundamental mechanical properties of the cell and is greatly affected by the intracellular tension...

This study presents a method based on carpet bombardment of immobilized cells with cavitating flows. For this, immobilized cancer cell lines are exposed to micro scale cavitating flows from the tip of a micro nozzle under the effect of cavitation microbubbles. The deformation as a result of cavitation bubbles on exposed cells differs from one cell...

This study presents an untethered magnetic manipulation technique for controlling a microrobot position under high rate laminar flows up to 4.5 mL/min. An increase in flow rate exponentially increases the drag force on the microrobot and negatively impacts its positioning accuracy. Increasing the longitudinal force generated by the microrobot's dri...

A three-dimensional profile reconstruction of live cells in dynamic cell cultures is a challenging problem due to the highly scattering nature of cell mediums. Furthermore, it is an interesting problem since these cultures present the optimal in vitro conditions that most closely resemble the cells’ natural conditions. In this paper, we report a ho...

A comprehensive study on machine and deep learning techniques for classification of normal and abnormal cervical cells by using pap smear images from Herlev dataset results are presented. This dataset includes 917 images and 7 different classes. All techniques used in this study are modeled by using Google Colab platform with scikit-learn and Keras...

This work proposes an interferometric method to simultenously measure the refractive index change and thickness of live cells under applied electrical fields. It may allow practical and accurate assessment of intracellular response to electrical stimulation.

This study reports the holographic reconstruction method for capturing high frequency vibration patterns on live cell membranes. Periodic vibration patterns generated on cell membrane is recorded by modulation of a high-speed camera in real-time.

This paper describes a mini unmanned glider's design, simulation, and manufacturing with a wing-folding mechanism. The mini-glider is designed for the CANSAT 2016 competition, which has the theme of a Mars glider concept with atmosphere data acquisition. The aim is to facilitate transportation and to land it to the destination point. Having a light...

his paper presents a concept for the semi- automatic Warehouse INventory management Device (WIND) that can be installed on reach truck (RT) vehicles. Inventory counting is a compulsory operational process in supply chain management. Current counting methods often threats employee’s health and safety and are not cost efficient. The WIND is designed...

In this paper, detailed magnetic force analysis of a 4-pole hybrid electromagnet system providing an advantage of full-redundant levitation is studied. The novel fragmented magnetic equivalent circuit method (MEC) is developed to accurately capture inherited nonlinear characteristics of 4-pole hybrid electromagnet to investigate force characteristi...

This paper describes a mini unmanned glider’s design, simulation, and manufacturing with a novel wing-folding mechanism. The mini-glider is designed for CanSat competition, which has a theme of a Mars glider concept with atmosphere data acquisition. The aim is to facilitate the transportation of the glider and to land it on the destination point by...

Magnetically actuated microrobot in a liquid media is faced with the problem of head-tilting reaction caused by its hydrodynamic structure and its speed while moving horizontally. When the instance microrobot starts a lateral motion, the drag force acting on it increases. Thus, the microrobot is unable to move parallel to the surface due to the exi...

This study presents a biomedical device prototype based on small scale hydrodynamic cavitation. The application of small scale hydrodynamic cavitation and its integration to a biomedical device prototype is offered as an important alternative to other techniques, such as ultrasound therapy, and thus constitutes a local, cheap, and energy-efficient...

In this study, we present a theoretical and numeric analysis of an untethered microrobot manipulation technique that can be used in a liquid environment. A microrobot, which is levitated on a pyrolytic graphite surface, allows us to achieve high precision positioning (at nano level) and control with lower external magnetic force requirements due to...

: In this article, we present a microrobot manipulation technique with high precision positional ability to move in a fluid environment with diamagnetic levitation. Untethered manipulation of microrobots by means of externally applied magnetic forces has been emerging as a promising field of research, particularly due to its potential for medical a...

This paper describes a mini unmanned glider's design, simulation, and manufacturing with a wing-folding mechanism. The mini-glider is designed for the CANSAT 2016 competition, which has the theme of a Mars glider concept with atmosphere data acquisition. The aim is to facilitate transportation and to land it to the destination point. Having a light...

Kidney stone and prostate hyperplasia are very common urogenital diseases all over the world. To treat these diseases, one of the ESWL (Extracorporeal Shock Wave Lithotripsy), PCNL (Percutaneous Nephrolithotomy), cystoscopes or open surgery techniques can be used. Cystoscopes named devices are used for in-vivo intervention. A flexible or rigid cyst...

Türkiye Robotbilim Konferansı, 2016 Özetçe-Minimal invaziv cerrahisi, açık ameliyatlarda hasta vücuduna açılan büyük kesiler yerine küçük kesilerden müdahale etme yöntemidir. Bu bildiride minimal invaziv yönteminin ürogenital sistem üzerinde kullanılmasını sağlayan sistoskopun tasarımı, deney düzeneği ve doğrulaması sunulmaktadır. Geliştirilen sist...

Recent studies show the destructive effect of the energy released from the collapse of cavitation bubbles, which are generated in micro domains, on the targeted surfaces. The cavitation phenomenon occurs at low local pressures within flow restrictive elements and strongly affects fluid flow regimes inside microchannels which results in spray format...

In this paper, we propose multi-view object detection methodology by using specific extended class of haar-like filters, which apparently detects the object with high accuracy in the unconstraint environments. There are several object detection techniques, which work well in restricted environments, where illumination is constant and the view angle...

In this paper, we discuss the single cell dispensing system to increase both the speed and the success rate of single cell dispensing. Two pairs of capacitance sensors are placed in a biochip to detect the flow velocity of cells, and the air pressure is applied to eject cells by synchronizing the timing. Then, the system theoretically has a capabil...

This paper presents on-demand microbeads delivery system in a microfluidic chip by magnetically driven microtool (MMT). The four of horizontally arranged permanent magnets and the piezoelectric vibrator are used to actuate the Ni based microtool precisely in the chip. The MMT injects the beads mechanically to flow and then into ejection operation p...

In this paper, on-chip particle loading and dispensing modules are presented with their results for the automation of a single particle retrieving from a microfluidic channel. Our proposed microfluidic chip has several modules. Each one of them has important functions as (a) loading micro-particles singly to main microfluidic flow by the aid of mag...

In this paper, we propose an illumination normalization approach, which apparently improves the face recognition accuracy in outdoor environments. The proposed approach computes the frequency variability and reflection direction on local face regions where the direction of the light source is unknown. It effectively recovers the illumination on a fa...

In this paper, we presented a design for an automated single cell loading and supply system that can be used with complex microfluidic applications requiring single cell loading such as the current nuclear transplantation method. The aim of the system is to automatically transfer mammalian donor (~15 ¿m) or egg (~100 ¿m) cells one by one from a c...

We have proposed cell coupling system for mammalian somatic cell cloning process in microfluidic chips. There are two kinds of nuclear transfer methods, microinjection and cell fusion; we selected the cell fusion method. Unlike the conventional method by the manual labor under the microscope, our aim is developing automated cloning work which is be...

We succeeded in automatic dispensing of a single swine oocyte (I=100 m) from a biochip to atmosphere using de-veloped cell ejection system. The developed system is composed of a cell loader, an inkjet mechanism and a capacitance sensor to dispense a droplet with a single cell. The performance of the sensor and the inkjet were evaluated using the fa...

Micro tasks dealing with live cells and tissues in bio science and technology require dexterous and skillful manipulation under microscope, and are mostly executed manually. Microfluidic cell manipulation techniques are being developed to achieve their automation to improve the manipulation productivity. We are developing a cell supply system, wher...

We proposed an automated cell coupling system for mammalian somatic cell cloning process in microfluidic chips. There are two kinds of nuclear transfer methods, microinjection and cell fusion; we selected the cell fusion method. Unlike the conventional manual method under the microscope, our aim is developing automated cloning wor k which is being...

In this paper, we presented a design for an automated cell supply system that can be used with complex microfluidic applications requiring single cell loading such as the current nuclear transplantation method. The aim of the system is to automatically transfer mammalian donor (~15 ¿m) or egg (~100 ¿m) cells one by one from a container to a PDMS...

Recently, micro valves to control some kinds of fluids in channels in a microchip have been developed. Now we pay attention to in-chip somatic cell cloning with microfluidic technology. There are some steps, cell supply, cutting, sorting, coupling, fusion and so on, for this work. And we focused on a cell supply system spending cells one by one in...