Huong Vu

• DPhil
• Senior Research Fellow at Oxford University Clinical Research Unit Vietnam

Carbapenem-resistant Enterobacterales (CRE) is a global public health threat with high mortality and limited effective treatments available. This is particularly problematic in low-and middle-income countries with uncontrolled use of antibiotics and lack of effective infection control practices. This study aims to understand clinical characteristic...

Carbapenem-resistant Enterobacterales (CRE) is a global public health threat with high mortality and limited effective treatments available. This is particularly problematic in low-and middle-income countries with uncontrolled use of antibiotics and lack of effective infection control practices. This study aims to understand clinical characteristic...

Background: To formulate effective strategies for antimicrobial stewardship (AMS) in primary care, it is crucial to gain a thorough understanding of factors influencing prescribers' behavior within the context. This qualitative study utilizes the Theoretical Domain Framework (TDF) to uncover these influential factors. Methods: We conducted a qualit...

Objectives To understand antibiotic prescribing and influencing factors to inform antimicrobial stewardship (AMS) interventions to reduce unwanted consequences of antibiotic use in hospitals in Vietnam, a lower-middle-income country in Asia. Methods We conducted a cross-sectional study of doctors at three tertiary hospitals using non-probability c...

Objective Blood culture (BC) sampling is recommended for all suspected sepsis patients prior to antibiotic administration. We examine barriers and enablers to BC sampling in three Southeast Asian countries. Design A Theoretical Domains Framework (TDF)-based survey, comprising a case scenario of a patient presenting with community-acquired sepsis a...

In low- and middle-income countries (LMIC) such as Vietnam, most hospitals at the lower level hospitals do not have access to clinical microbiology diagnostics, which could hamper the global efforts of antimicrobial resistance (AMR) control 1. Therefore, adapted laboratory solutions for LMIC are an important area for further investigations and shou...

Objectives To investigate the feasibility of retrospective prescription-based review and to describe the antibiotic prescribing patterns to provide information for an antimicrobial stewardship programme in Viet Nam Methods This study was conducted in two provincial-level hospitals between February and April 2020. Reviews were done by a clinical te...

Low awareness of antibiotics and antibiotic resistance may lead to inappropriate antibiotic use and contribute to the problem of antibiotic resistance. This study explored levels and determinants of antibiotic awareness in a rural community in northern Vietnam, through a cross-sectional survey of 324 households in one commune of Ha Nam Province. Aw...

Background Blood culture (BC) sampling is recommended for all suspected sepsis patients prior to antibiotic administration. Here, we aimed to identify barriers and enablers to BC sampling in three Southeast Asian countries. Methods We conducted a systematic review of studies evaluating barriers/enablers to BC sampling from 1900 to 2020 globally (PR...

Introduction Antimicrobial stewardship (AMS) is an important strategy to control antimicrobial resistance. Resources are available to provide guidance for design and implementation of AMS programmes, however these may have limited applicability in resource-limited settings including those in Asia. This scoping review aims to identify context-specif...

Objectives Antibiotic overuse is one of the main drivers of antimicrobial resistance (AMR), especially in low-income and middle-income countries. This study aimed to understand the perceptions and views towards AMR, antibiotic prescribing practice and antimicrobial stewardship (AMS) among hospital physicians in Jakarta, Indonesia. Design Cross-sec...

Objectives This study aimed to analyze the current state of antimicrobial stewardship (AMS) in hospitals in Viet Nam, a lower middle-income country, to identify factors determining success in AMS implementation and associated challenges to inform planning and design of future programs. Methods We conducted a mixed-methods study in seven acute-care...

Objectives To investigate the feasibility of establishing hospital-based antimicrobial stewardship (AMS) programmes comprising action-planning, educational interventions and data feedback in two provincial-level hospitals in Viet Nam. Design and setting This was an implementation research using participatory action process and existing resources f...

Objectives: Antibiotic overuse is one of the main drivers of antimicrobial resistance (AMR), especially in low and middle-income countries. This study aimed to gain an understanding of perceptions, views, and practices regarding AMR, antibiotic prescribing, and stewardship (AMS) among hospital physicians in Jakarta, Indonesia. Design: cross-section...

Background Antimicrobial misuse is common in low-income and middle-income countries (LMICs), and this practice is a driver of antibiotic resistance. We compared community-based antibiotic access and use practices across communities in LMICs to identify contextually specific targets for interventions to improve antibiotic use practices. Methods We d...

Background Antimicrobial stewardship (AMS) programmes have been implemented around the world to guide rational use of antibiotics but implementation is challenging, particularly in low- and middle-income countries, including Vietnam. Understanding factors influencing doctors’ prescribing choices for empirical treatment can help design AMS intervent...

In recent years, serosurveillance has gained momentum as a way of determining disease transmission and immunity in populations, particularly with respect to vaccine-preventable diseases. At the end of 2017, the Oxford University Clinical Research Unit and the National Institute of Hygiene and Epidemiology held a meeting in Vietnam with national pol...

Background: As in many other low and middle income countries (LIMCs), Vietnam has experienced a major growth in the pharmaceutical industry, with large numbers of pharmacies and drug stores, and increasing drug expenditure per capita over the past decade. Despite regulatory frameworks that have been introduced to control the dispensing and use of...

Background: Streptococcus suis is a zoonotic disease mainly affecting men of working age and can result in death or long-term sequelae, including severe hearing loss and vestibular dysfunction. We aimed to quantify the burden of disease and economic impact of this infection in Viet Nam. Methods: The annual disease incidence for the period 2011-2...

[This corrects the article DOI: 10.1371/journal.pone.0206760.].

Introduction Ventilator associated respiratory infections (VARIs) are the most common hospital acquired infections in critical care worldwide. This work aims to estimate the total annual direct hospital cost of treating VARI throughout Vietnam. Methods A costing model was constructed to evaluate the excess cost of diagnostics and treatment of VARI...

Assumed aetiology of ventilator associated respiratory infections. (DOCX)

Background Ventilator-associated pneumonia (VAP) is the commonest hospital-acquired infection (HAI) in intensive care. In Asia, VAP is increasingly caused by resistant gram-negative organisms. Despite the global antimicrobial resistance crisis, the epidemiology of VAP is poorly documented in Asia. Methods We systematically reviewed literature publ...

Objectives: Streptococcus suis is a zoonotic cause of severe meningitis and sepsis in humans. We aimed to assess the long-term outcomes in patients who survived S. suis infection, in particular the progress and impact of vestibulocochlear sequelae. Methods: This case-control study evaluated outcomes of S. suis infection at discharge and 3 and 9...

Porcine reproductive and respiratory syndrome (PRRS) outbreaks in pigs are associated with increased susceptibility of pigs to secondary bacterial infections, including Streptococcus suis - an important zoonotic pathogen causing bacterial meningitis in humans. This case-control study examined the association between human S. suis infection and PRRS...

We assessed consumption of raw pig blood, which is a risk factor for Streptococcus suis infection in Vietnam, by using a mix-method design. Factors associated with consumption included rural residency, age, sex, occupation, income, and marital status. We identified risk groups and practices and perceptions that should be targeted by communication p...

Details on data collection, characteristics of participants, questionnaire, and data analysis for raw pig blood consumption and potential risk for Streptococcus suis infection, Vietnam.

Streptococcus suis, a bacterium that affects pigs, is a neglected pathogen that causes systemic disease in humans. We conducted a systematic review and meta-analysis to summarize global estimates of the epidemiology, clinical characteristics, and outcomes of this zoonosis. We searched main literature databases for all studies through December 2012...

Details of publications in a review of the epidemiology, clinical manifestations, and outcome of Streptococcus suis infection in humans.

Streptococcus suis, a pig bacterium, is an emerging but neglected zoonotic disease in humans. We conducted a systematic review and meta-analysis to summarize the global estimates on the epidemiology, clinical characteristics and outcomes of this important zoonosis. Main literature databases were searched for all studies by December 2012 using the s...

Community acquired K. pneumoniae pneumonia is still common in Asia and is reportedly associated with alcohol use. Oropharyngeal carriage of K. pneumoniae could potentially play a role in the pathogenesis of K. pneumoniae pneumonia. However, little is known regarding K. pneumoniae oropharyngeal carriage rates and risk factors. This population-based...

Systemic Streptococcus suis infections in sick pigs from farms with confirmed porcine reproductive and respiratory syndrome and temporal distribution of outbreaks of porcine reproductive and respiratory syndrome in swine, 3 provinces, Vietnam, 2010.

Vitamin D is necessary to maintain healthy bones, and may prevent other chronic diseases. There is limited information regarding the vitamin D status of people living in climates with relatively high ambient ultraviolet radiation. We therefore aimed to determine serum 25(OH)D levels in a group of office-workers in subtropical Australia. We collecte...

Hepatitis B is a significant public health challenge within some subpopulations in Australia, including Chinese and Vietnamese migrants. There has been limited research on hepatitis B knowledge and actions in these communities. The authors conducted a self-administered survey among 442 Chinese and 433 Vietnamese in Brisbane. Generally, the knowledg...

Sun exposure is the main source of vitamin D. Increasing scientific and media attention to the potential health benefits of sun exposure may lead to changes in sun exposure behaviors. To provide data that might help frame public health messages, we conducted an online survey among office workers in Brisbane, Australia, to determine knowledge and at...