Hugo Cayuela

Claude Bernard University Lyon 1 | UCBL · Laboratoire de biométrie et biologie evolutive (LBBE)

1. Temperature is a critical driver of ectotherm life history strategies, whereby a warmer environment is associated with increased growth, reduced longevity, and accelerated senescence. Increasing evidence indicates that thermal adaptation may underly such life history shifts in wild populations. Single Nucleotide Polymorphisms (SNPs) and Copy Num...

Significance Using long-term demographic studies, we showed that warmer temperatures are associated with increased senescence rates and decreased lifespans in four amphibian species that are widely distributed across two continents (North America and Europe). Our study highlights the role of changing climatic conditions in the aging of ectotherms i...

Sex-related differences in mortality are widespread in the animal kingdom. Although studies have shown that sex determination systems might drive lifespan evolution, sex chromosome influences on aging rates have not been investigated so far, likely due to an apparent lack of demographic data from clades including both XY (with heterogametic males)...

Comparative studies of mortality in the wild are necessary to understand the evolution of aging; yet, ectothermic tetrapods are underrepresented in this comparative landscape, despite their suitability for testing evolutionary hypotheses. We present a study of aging rates and longevity across wild tetrapod ectotherms, using data from 107 population...

Habitat anthropization is a major driver of global biodiversity decline. Although most species are negatively affected, some benefit from anthropogenic habitat modifications by showing intriguing life-history responses. For instance, increased recruitment through higher allocation to reproduction or improved performance during early-life stages cou...

Epigenetic modifications are thought to be one of the molecular mechanisms involved in plastic adaptive responses to environmental variation. However, studies reporting associations between genome-wide epigenetic changes and habitat-specific variations in life history traits (e.g., lifespan, reproduction) are still scarce, likely due to the recent...

Actuarial senescence, the increase in adult mortality risk with increasing age, is a widespread phenomenon across the animal kingdom. Although between-species variation in the rate of increase in mortality as organisms age (i.e. ageing rate) is now well documented, the occurrence of variation in ageing rate within a given species remains much more...

In marine species experiencing intense fishing pressures, knowledge of genetic structure and local adaptation represent a critical information to assist sustainable management. In this study, we performed a landscape genomics analysis in the American lobster to investigate the issues pertaining to the consequences of making use of putative adaptive...

Amphibia is the most threatened class among vertebrates, with more than 40% of the species threatened with extinction. Pollution is thought to alter amphibian population dynamics. With the growing interest in behavioral ecotoxicology, the neurotoxic organophosphate pesticides are of special concerns. Understanding how the exposure to neurotoxics le...

The Anthropocene is tightly associated with a drastic loss of species worldwide, and consequently, with the disappearance of key ecosystem functions. The ongoing reduction in species functionality is driven by global and local threats. The orders Testudines (turtles and tortoises) and Crocodilia (crocodilians and alligators) contain numerous threat...

Human activities and resource exploitation led to a massive decline of wild salmonid populations, consequently numerous conservation programs have been developed to supplement wild populations. However, many studies documented reduced fitness of hatchery-born relative to wild fish. Here, by using both RNA sequencing and Whole Genome Bisulfite Seque...

Compensatory recruitment is a key demographic mechanism that has allowed the coexistence of populations of susceptible amphibians with Batrachochytrium dendrobatidis (Bd), a fungus causing one of the most devastating emerging infectious disease ever recorded among vertebrates. However, the underlying processes (e.g. density‐dependent increase in su...

Phenotypic plasticity, the ability of one genotype to produce different phenotypes in different environments, plays a central role in species' response to environmental changes. Transgenerational plasticity (TGP) allows the transmission of this environmentally induced phenotypic variation across generations, and can influence adaptation. To date, t...

Durant le 20 ème siècle, les populations de Sonneurs à ventre jaune (Bombina variegata) ont subi un net déclin en Europe de l'Ouest, et en France tout particulièrement. Les causes de cette régression sont possiblement multiples, incluant la perte et la fragmentation d'habitat, ainsi que les changements climatiques. De nos jours, les forêts de produ...

Dispersal is a central process in ecology and evolution with far reaching consequences for the dynamics and genetics of spatially structured populations (SSPs). Individuals can adjust their decisions to disperse according to local fitness prospects, resulting in context-dependent dispersal. By determining dispersal rate, distance and direction , th...

Across a species range, multiple sources of environmental heterogeneity, at both small and large scales, create complex landscapes of selection, which may challenge adaptation, particularly when gene flow is high. One key to multidimensional adaptation may reside in the heterogeneity of recombination along the genome. Structural variants, like chro...

The interplay between recombination rate, genetic drift and selection modulates variation in genome-wide ancestry. Understanding the selective processes at play is of prime importance toward predicting potential beneficial or negative effects of supplementation with domestic strains (i.e., human-introduced strains). In a system of lacustrine popula...

When facing an emerging infectious disease of conservation concern, we often have little information on the nature of the host-parasite interaction to inform management decisions. However, it is becoming increasingly clear that the life-history strategies of host species can be predictive of individual and population-level responses to infectious d...

Increasing evidence shows that structural variants represent an overlooked aspect of genetic variation with consequential evolutionary roles. Among those, copy number variants (CNVs), including duplicated genomic region and transposable elements (TEs) may contribute to local adaptation and/or reproductive isolation among divergent populations. Thos...

The molecular mechanisms underlying intraspecific variation in life history strategies are still poorly understood, despite the importance of this question for understanding of organism's responses to environmental variability. Theoretical work proposed that epigenetic mechanisms such as DNA methylation might regulate intraspecific variation in lif...

Understanding the mechanisms underlying population decline is a critical challenge for conservation biologists. Both deterministic (e.g. habitat loss, fragmentation, and Allee effect) andstochastic (i.e. demographic and environmental stochasticity) demographic processes are involved in population decline. Simultaneously, a decrease of population si...

Across a species range, spatially-varying environments can drive the evolution of local adaptation. Multiples sources of environmental heterogeneity, at small and large scales, draw complex landscapes of selection which may challenge adaptation, particularly when gene flow is high. Because linkage opposes gene flow but also limits the efficiency of...

Aim When modelling future or past geographic distributions of a species, attention should be paid to the possible differentiated responses to climate changes between lineages. Dispersal also plays an important role in the capacity of species to track suitable climate, which is particularly relevant for amphibians with limited dispersal ability. In...

Aging evolutionary theories predict that patterns of actuarial and reproductive senescence should be aligned, with a common onset of senescence set at the age of first reproduction. However, a few empirical studies reported asynchrony between actuarial and reproductive senescence. This asynchrony is expected to be particularly pronounced in organis...

Copy number variants (CNVs) are a major component of genotypic and phenotypic variation in genomes. To date, our knowledge of genotypic variation and evolution has largely been acquired by means of single nucleotide polymorphism (SNPs) analyses. Until recently, the adaptive role of structural variants (SVs) and particularly that of CNVs has been ov...

Gene flow has tremendous importance on local adaptation, by influencing the fate of de novo mutations, maintaining standing genetic variation, and driving adaptive introgression. Furthermore, structural variation as chromosomal rearrangements may facilitate adaptation despite high gene flow. However, our understanding of evolutionary mechanisms imp...

Increasing evidence shows that structural variants represent an overlooked aspect of genetic variation with consequential evolutionary roles. Among those, copy number variants (CNVs), including duplicated genomic region and transposable elements (TEs) may contribute to local adaptation and/or reproductive isolation among divergent populations. Thos...

Identifying the drivers of population fluctuations in spatially distinct populations remains a significant challenge for ecologists. Whereas regional climatic factors may generate population synchrony (i.e., the Moran effect), local factors including the level of density‐dependence may reduce the level of synchrony. Although divergences in the scal...

Dispersal is a central process in ecology and evolution. It strongly influences the dynamics of spatially structured populations and affects evolutionary processes by shaping patterns of gene flow. For these reasons, dispersal has received considerable attention from ecologists, evolutionary biologists, and conservationists. Although it has been st...

There is growing evidence that anthropogenic landscapes can strongly influence the evolution of dispersal, particularly through fragmentation, and may drive organisms into an evolutionary trap by suppressing dispersal. However, the influence on dispersal evolution of anthropogenic variation in habitat patch turnover has so far been largely overlook...

Copy number variants (CNVs) are a major component of genotypic and phenotypic variation in genomes. Yet, our knowledge on genotypic variation and evolution is often limited to single nucleotide polymorphism (SNPs) and the role of CNVs has been overlooked in non-model species, partly due to their challenging identification until recently. Here, we d...

Patterns of actuarial senescence can be highly variable among species. Previous comparative analyses revealed that both age at the onset of senescence and rates of senescence are linked to position of a species along the fast‐slow life‐history continuum. As there are few long‐term datasets of wild populations with known‐age individuals, intraspecif...

Phenotypic plasticity, the ability of one genotype to produce different phenotypes in different environments, plays a central role in species’ response to environmental changes. Transgenerational plasticity (TGP) allows the transmission of this environmentally-induced phenotypic variation across generations, and can influence adaptation. To date, t...

There is growing evidence that anthropogenic landscapes can strongly influence the evolution of dispersal, particularly through fragmentation, and may drive organisms into an evolutionary trap by suppressing dispersal. However, the influence on dispersal evolution of anthropogenic variation in habitat patch turnover has so far been largely overlook...

Assessing the immediate and long‐term evolutionary consequences of human‐mediated hybridization is of major concern for conservation biology. Several studies have documented how selection in interaction with recombination modulates introgression at a genome‐wide scale, but few have considered the dynamics of this process within and among chromosome...

Population genetic theory states that adaptation most frequently occurs from standing genetic variation, which results from the interplay between different evolutionary processes including mutation, chromosomal rearrangements, drift, gene flow and selection. To date, empirical work focusing on the contribution of standing genetic variation to local...

Kin selection and dispersal play a critical role in the evolution of cooperative breeding systems. Limited dispersal increases relatedness in spatially structured populations (population viscosity), with the result that neighbours tend to be genealogical relatives. Yet the increase in neighbours’ fitness-related performance through altruistic inter...

Actuarial senescence has been viewed for a long time as an inevitable and uniform process. However, the work on senescence has mainly focused on endotherms with deterministic growth and low regeneration capacity during the adult stage, leading to a strong taxonomic bias in the study of aging. Recent studies have highlighted that senescence could in...

Understanding the mechanisms underlying biological extinctions is a critical challenge for conservation biologists. Both deterministic (e.g. habitat loss, fragmentation) and stochastic (i.e. demographic stochasticity, Allee effect) demographic processes are involved in population decline. Simultaneously, a decrease of population size has far-reachi...

Assessing the immediate and long-term evolutionary consequences of human-mediated hybridization is of major concern for conservation biology. Several studies have documented how selection in interaction with recombination modulates introgression at a genome-wide scale, but few have considered the dynamics of this process within and between chromoso...

Actuarial senescence appears to be a common process, and senescence patterns are highly variable across the tree of life. To date, studies on animal senescence have largely focused on model species, such as as fruit flies, humans and a few other endotherms. In contrast, our knowledge about ageing remains fragmentary in ectotherm vertebrates, such a...

Abstract Transport infrastructure such as roads has been reported to negatively affect dispersal. Their effects on dispersal are thought to be complex, depending on the characteristics of the structure and the intensity of the traffic using it. In addition, individual factors, such as age, may strongly affect dispersal decisions and success when in...

Patterns of actuarial senescence can be highly variable among species. Previous comparative analyses revealed that both age at the onset of senescence and rates of senescence are linked to the species' position along the fast-slow life-history continuum. As there are few long-term datasets of wild populations with known-age individuals, intraspecif...

Actuarial senescence (hereafter 'senescence') has been viewed for a long time as an inevitable and uniform process. However, the work on senescence has mainly focused on endotherms (especially mammals) with deterministic growth and low regeneration capacity at adult stages, leading to a strong taxonomic bias in the study of aging. Recent studies ha...

Relocations are increasingly popular among wildlife managers despite often low rates of relocation success in vertebrates. In this context, understanding the influence of extrinsic (e.g., relocation design, habitat characteristics) and intrinsic factors (e.g., age and sex) on demographic parameters, such as survival, that regulate the dynamics of r...

Dispersal is a key process in ecology and evolution. Both theoretical and empirical evidence in actively dispersing organisms support the general notion that the use of nearly straight dispersal paths is a highly efficient way to maximize dispersal success in heterogenous landscapes. In homogeneous landscapes, in contrast, the benefits of a straigh...

Life-history theory states that, during the lifetime of an individual, resources are allocated to either somatic maintenance or reproduction. Resource allocation trade-offs determine the evolution and ecology of life-history strategies and determine an organisms’ position along the fast-slow continuum. Theory predicts that environmental stochastici...

Understanding age-dependent mortality processes is a critical challenge for population biologists. Actuarial senescence appears to be a common process across the tree of life. Senescence patterns are highly variable in pluricellular organisms: senescence can be gradual or sharp and its onset may be early or delayed. By contrast, studies revealed th...

Dispersal is a central mechanism in ecology and evolution. Dispersal evolution is driven by a trade-off between costs and benefits, which is influenced by interindividual variability and local environmental conditions (context-dependent dispersal). Many studies have investigated how dispersal decisions may be influenced by environmental factors, in...

1. Understanding the mechanisms that regulate the dynamics of spatially structured populations (SSP) is a critical challenge for ecologists and conservation managers. Internal population processes such as births and deaths occur at a local level, while external processes such as dispersal take place at an inter-population level. At both levels, den...

Kin selection and dispersal play a critical role in the evolution of cooperative breeding systems. Limited dispersal dramatically increases relatedness in spatially structured populations (population viscosity), with the result that neighbours tend to be genealogical relatives. Yet the increase in neighbour performance through altruistic interactio...

Life-history theory states that, during the lifetime of an individual, resources are allocated to either somatic maintenance or reproduction. Resource allocation trade-offs determine the evolution and ecology of life-history strategies and determine an organisms' position along the fast-slow continuum. Theory predicts that environmental stochastici...

Dispersal is one of the main processes that determine community structure. Individuals make dispersal decisions according to environmental and/or social cues that reflect the fitness prospects in a given patch. The presence and abundance of heterospecifics within the same ecological guild, and/or their breeding success, may act as public informatio...

Dispersal is a central process in ecology and evolution. It strongly influences the dynamics of spatially structured populations, by affecting population growth rate and local colonization-extinction processes. Dispersal can also influence evolutionary processes because it determines rates and patterns of gene flow in spatially structured populatio...

Dispersal is a central process in ecology and evolution. It strongly influences the dynamics of spatially structured populations, by affecting population growth rate and local colonization-extinction processes. Dispersal can also influence evolutionary processes because it determines rates and patterns of gene flow in spatially structured populatio...

Relocations are increasingly popular among wildlife managers despite sharp debate and low rate of relocation success in vertebrates. In this context, understanding the influence of extrinsic (e.g., relocation design, habitat characteristics) and intrinsic factors (e.g., age and sex) on demographic parameters such as survival that regulate the dynam...

Understanding the impact of weather fluctuations on demographic parameters is of crucial interest to biodiversity research in a context of global climate change. Amphibians are valuable candidates for investigating this topic due to their strong physiological dependence on water availability and temperature. In this study, we took advantage of data...

Dispersal (i.e. movement from a natal or breeding site to another breeding site) is a central process in ecology and evolution as it affects the eco-evolutionary dynamics of spatially structured populations. Dispersal evolution is regulated by the balance between costs and benefits, which is influenced by the individual phenotype (i.e. phenotype-de...

Dispersal is a central process in ecology and evolution. At the individual level, the three stages of the dispersal process (i.e. emigration, transience and immigration) are affected by complex interactions between phenotypes and environmental factors. Condition and context‐dependent dispersal have far‐reaching consequences, both for the demography...