Hualin Liu

Hualin Liu
Sun Yat-Sen University | SYSU · School of Marine Sciences

PhD

About

26
Publications
4,046
Reads
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203
Citations
Citations since 2016
26 Research Items
203 Citations
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201620172018201920202021202201020304050
201620172018201920202021202201020304050
Additional affiliations
August 2020 - present
Sun Yat-Sen University
Position
  • Zhuhai
Description
  • post-doctor, working on marine microbiomes
Education
September 2012 - December 2019
Huazhong Agricultural University
Field of study
  • Bacillus thuringiensis

Publications

Publications (26)
Article
Full-text available
Methicillin-resistant Staphylococcus aureus (MRSA) is a major human pathogen that is difficult to treat because of its resistance to several widely used antibiotics. The present study aimed to identify novel anti-MRSA bacteriocins in a prominent producer of bacteriocins, Bacillus cereus group.
Article
Bacteriocins are bacterial-derived peptides that exhibit antimicrobial activity and can be used as food preservatives. Here, using the indicator strain Bacillus cereus CMCC63301, we screened and identified a Bacillus thuringiensis LX43 strain that exhibits potent antimicrobial activity and harbors a putative leaderless bacteriocin gene cluster (thn...
Article
Full-text available
Determinism and stochasticity in microbial community composition decisions have attracted wide attention. However, there is no consensus on their interrelationships and relative importance, and the mechanism controlling the interaction between the two ecological processes remains to be revealed. The interaction of the two ecological processes on th...
Article
Full-text available
Bacillus amyloliquefaciens is a gram-positive, nonpathogenic, endospore-forming, member of a group of free-living soil bacteria with a variety of traits including plant growth promotion, production of antifungal and antibacterial metabolites, and production of industrially important enzymes. We have attempted to reconstruct the biogeographical stru...
Article
Bacillus thuringiensis (Bt) has been used as the most successful microbial pesticide for decades. Its toxin genes are used for the development of GM crops against pests. We previously developed a web-based insecticidal gene mining tool BtToxin_scanner. It has been frequently used by many researchers worldwide. However, it can only handle the genome...
Article
Full-text available
Bacteriocins have attracted increasing interest because of their potential as natural preservatives. Recent studies showed that the Bacillus cereus group is a prominent producer of bacteriocins. Using a laboratory-based screening strategy, we identified a strain in the B. cereus group, B. toyonensis XIN-YC13, with antimicrobial activity against B....
Preprint
Full-text available
More and more frequently, genomics and comparative genomics have been used as routine methods for general microbiological research. However, using several tools or even writing some scripts are required for completing a simple analysis, which is complicated for most biological researchers. To simplify the operation process, particularly for the con...
Article
Full-text available
In recent years, bacteriocins have attracted considerable interest for use as natural food preservatives against spoilage and pathogenic microorganisms. Recent studies have shown that the strains of Bacillus cereus group produce a range of highly diverse bacteriocins. In this study, we screened a large number of Bacillus cereus group strains and is...
Article
Full-text available
Circular bacteriocins are promising biopreservatives, and it is important to identify more novel circular bacteriocins to enhance the current arsenal of antimicrobials. In this study, we used an in silico approach to identify a large number of novel circular bacteriocins and classified these bacteriocins into 28 groups rather than the 2 groups that...
Preprint
Full-text available
Bacillus thuringiensis (Bt) which is a spore-forming gram-positive bacterium, has been used as the most successful microbial pesticide for decades. Its toxin genes (cry) have been successfully used for the development of GM crops against pests. We have previously developed a web-based insecticidal gene mining tool BtToxin_scanner, which has been pr...
Preprint
Full-text available
Genomics and comparative genomics have been increasingly used as routine methods for general microbiological researches. However, it is usually necessary to call several tools or even write some scripts to complete some simple analysis, which is complicated for most biological researchers. To simplify the operation process, especially for the conve...
Preprint
Full-text available
Genomics and comparative genomics have been increasingly used as routine methods for general microbiological researches. However, it is usually necessary to call several tools or even write some scripts to complete some simple analysis, which is complicated for most biological researchers. To simplify the operation process, especially for the conve...
Preprint
Full-text available
Genomics and comparative genomics have been increasingly used as routine methods for general microbiological researches. However, it is usually necessary to call several tools or even write some scripts to complete some simple analysis, which is complicated for most biological researchers. To simplify the operation process, especially for the conve...
Preprint
Full-text available
More and more frequently, genomics and comparative genomics have been used as routine methods for general microbiological research. However, using several tools or even writing some scripts are required for completing a simple analysis, which is complicated for most biological researchers. To simplify the operation process, particularly for the con...
Article
Full-text available
Despite the successful application of crystal proteins (Cry) from Bacillus thuringiensis as biological control agents against insects, there is an increasing demand to identify new Cry toxins having higher toxicity and broad-spectrum activity against insects and plant-parasitic nematodes. To find novel Cry toxins, we screened 100 whole-genome seque...
Article
Full-text available
Understanding the genetic basis of host shifts is a key genomic question for pathogen and parasite biology. The Bacillus cereus group, which encompasses Bacillus thuringiensis and Bacillus anthracis, contains pathogens that can infect insects, nematodes, and vertebrates. Since the target range of the essential virulence factors (Cry toxins) and man...
Article
Full-text available
Transposon mutagenesis and subsequent phenotype-driven screening have been extensively used to annotate gene function and uncover the mechanisms of biological phenomena. During this process, the resulting phenotypic differences are specifically attributable to the disrupted genes. In this study, the complementation of the mini-Tn10 transposon-disru...
Article
Bacillus thuringiensis serovar alesti was used to control caterpillars from 1970s. Here we reported the complete genome of BGSC 4C1, the type strain of this serovar. It has a circular chromosome and six plasmids. The largest plasmid pBMB267 contains five insecticidal crystal protein genes (two copies of cry1Ae, cry1Gb, cry2Ab, and a novel cry1M-typ...
Article
Root-knot nematodes (RKNs) which can infect almost all crops lead to huge economic losses in agriculture around the world. Unavailability of effective and environmentally friendly control of RKNs provides an opportunity to nematicidal bacteria. Fictibacillus phosphorivorans G25-29 is a gram-positive and spore-forming bacterium with nematicidal capa...
Article
Full-text available
Plant-parasitic nematodes were found in 4 of the 12 clades of phylum Nematoda. These nematodes in different clades may have originated independently from their free-living fungivorous ancestors. However, the exact evolutionary process of these parasites is unclear. Here, we sequenced the genome sequence of a migratory plant nematode, Ditylenchus de...
Article
Full-text available
Due to the rapidly increasing prevalence of multidrug-resistant bacterial strains, the need for new antimicrobial drugs to treat infections has become urgent. Bacteriocins, which are antimicrobial peptides of bacterial origin, are considered potential alternatives to conventional antibiotics and have attracted widespread attention in recent years....

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Projects

Projects (3)
Archived project
Project
Resources of bacteria, such as spore-forming Bacilli and fungi from soil and medicinal plants to control plant pathogens, such as parasitic nematodes and human and animal diseases, such as tumor in combination with genomics and metabolomics.