Hossein Hooshyar

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Verified

Hossein verified their affiliation via an institutional email.

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• Ph.D
• Professor (Full) at Kashan University of Medical Sciences

Abstract Background: We aimed to review and analyze the status of Medical Parasitology course including current problems and challenges on human resources, infrastructure, research capacities, educational and investigative priorities in Iran, and to develop a roadmap and future development in this field. Methods: A questionnaire was prepared to obt...

Fascioliasis and Dicrocoeliasis are important trematode infections that affect humans and ruminants worldwide. Molecular techniques have a conclusive role in detection of liver flukes. The purpose of the current study was to find outthe genotypic diversity of Fasciola and Dicrocoelium spp. isolated from different hosts in Iran. Totally, 160 and 200...

Fascioliasis is a common hepatic parasitic disease that is caused by Fasciola, resulting in significant economic losses by reducing production and consigning viscera in animals. Currently, there is little research regarding the impact of chemical compounds on the ultrastructure and motility of adult F. hepatica. The present study aims to assess the...

Background: Opportunistic infections such as mucormycosis, are spread in COVID-19 patients due to the use of corticosteroids therapy. This study aimed to determine the prevalence of mucormycosis in patients infected with the delta strain of the COVID-19 virus and evaluated some effective factors in the prevalence and patient prognosis. Methods: Thi...

Background: Dicrocoeliasis is an important helminthic zoonosis reported from many parts of the world. Due to low-performance medications, drug delivery is a great challenge in improving the treatment of this liver fluke infection. We aimed to determine the anthelmintic properties of Nanosilver oxide (AgO) against Dicrocoelium dendriticum infection....

Background: Acanthamoeba species are recognized as the most prevalent free-living amoebae (FLA). They can cause granulomatous amebic encephalitis (GAE) and pulmonary and ocular infections. The present study aimed to isolate and identify Acanthamoeba genotypes in cancer patients referred to Kashan’s hospitals in Central Iran. Methods: This cross-sec...

Background and Aim: Toxoplasma gondii is one of the important food-borne parasitic pathogens that infect humans and a wide range of warm-blooded animals. Consumption of poultry meat, especially chicken, is a potential risk of transmission of toxoplasmosis to humans. This study aimed to determine the prevalence of T. gondii infection in industrial b...

Sarcocystis is one of the most prevalent protozoan parasites that infect many domestic and wild animals worldwide. Ruminants as one of the sources of meat products for the human are exposed to contamination with these parasites. This study aimed to determine the prevalence of Sarcocystis in slaughtered ruminants, using the histology method in the K...

Malaria is the most common cause of fever in travellers returning from malaria-endemic areas. Imported malaria can hinder the progress of elimination programs. In the present study, we describe an imported malaria case in a 45-year-old Iranian man from Ivory Coast who had returned to Iran after taking annual leave. He was hospitalized in Kamkar-Ara...

Background The mechanisms underlying the clinical outcome disparity during human infection with Giardia duodenalis are still unclear. In recent years, evidence has pointed to the roles of host factors as well as parasite’s genetic heterogeneity as major contributing factors in the development of symptomatic human giardiasis. However, it remains con...

Objectives: Endolimax is a protozoan genus belongs to Amoebida order. The member of this genus occurrence in a vast range of vertebrate and invertebrate, but the species of this genus are not well studied. This review aimed to provide an updated list and some summarized information on Endolimax species, which were identified in human and animals up...

Introduction: Trichostrongyloiasis is a prevalent infection in humans and some animals worldwide. Morphology is a reliable tool for identifying Trichostrongylus species. This study aimed to determine the prevalence of Trichostrongylus infection in livestock and compare the morphometric characteristics of the species in sheep and goats referred to K...

Cutaneous leishmaniasis (CL) frequently occurs in many rural and urban areas of Iran. Leishmania major and L. tropica are principally two causative agents of CL in Iran. We report here a case of leishmaniasis of the ear in a 61-year-old man referred to the Reference laboratory, Kashan, central Iran, in Jan 2022. He suffered from a 2-month history o...

Background: Dicrocoeliasis and fascioliasis are foodborne parasitic diseases of the biliary tract, resulting from Dicrocoelium dendriticum and Fasciola hepatica causing extensive financial losses and serious health problems in ruminants. Due to low-performance medications, drug delivery is a tremendous project to improve interventions available for...

Leishmaniasis is a vector-borne protozoan disease transferred by the sting of a female sandfly. Currently, both cutaneous and visceral forms of leishmaniasis (VL) are observed in Iran. Cutaneous leishmaniasis (CL) is reported in 18 provinces in the country in rural (zoonotic) and urban (anthroponotic) forms. VL is endemic in some areas of Iran. Var...

Acanthamoeba spp. are the most common freeliving amoeba worldwide, inducing life-threatening diseases such as Granulomatous Amoebic Encephalitis, pulmonary infection, and amoebic keratitis. This study aimed to identify the FLA and Acanthamoeba genotypes in patients with pulmonary symptoms suspected of cancer in Kashan’s hospitals, Kashan, Iran. Thi...

Malaria is an imported disease in non-endemic regions of Iran. Imported malaria cases to Iran mostly come from illegal immigrants from neighboring eastern countries. The present study describes a case of imported malaria in a 14-monthold Afghan boy with prolonged fever, vomiting, and diarrhea. He was referred and hospitalized in Shahid Beheshti, Ka...

Accurate diagnosis of Entamoeba histolytica is important, as it is known as a causative agent for both invasive intestinal and extra-intestinal amoebiasis. Amoebiasis has a worldwide distribution, especially in developing countries, and it is responsible for up to 100,000 fatal cases annually. A number of diagnostic methods, including microscopy, c...

Aim: Despite the various studies done in the field of cutaneous leishmaniasis treatment, there is still no perfect and safe drug for definite treatment of this disease. Therefore, the quest to find an appropriate drug continues. Previous studies have shown that auranofin has anti-leishmanial activity; therefore, in this study; the effect of auranof...

Aims: In vitro cultivation of digenea would help the development of effective treatments and studies of the biology of the parasites. The goal of the present study was to optimize culture conditions for the maintenance liver fluke, Dicrocoelium dendriticum. Materials and Methods: Forty fresh D. dendriticum were collected from the sheep liver and wa...

Acute appendicitis is one of the most common causes of abdominal emergent surgical disease worldwide. Enterobius vermicularis, a human intestinal parasite, is reported to be associated with acute appendicitis. We report a case of an 8-year-old girl who was admitted to the emergency unit with complaints of severe abdominal pain and was diagnosed wit...

Original ArticleAims: Blastocystis species are one of the most common enteric protist infections in humans and some animals worldwide. Molecular studies have shown that there is a high level of genetic variation among Blastocystis isolates. The aim of this study was to identify the subtypes and frequency of Blastocystis isolates in patients who ref...

OriginaAims: The control of fascioliasis has depended on the utilization of a predetermined number of anthelmintic drugs. Nonetheless, the resistance of antifasciolid is presently boundless, and there is a need for potential drug properties of medicinal plants as new medications against Fasciola spp. to interrupt the parasite transmission. Material...

Aims: Hydatidosis is an important zoonotic disease that is caused by a tiny tapeworm, namely Echinococcus granulosus. In this study, three polymerase chain reaction (PCR)-based methods, including, high resolution melting (HRM) analysis, DNA sequencing, and PCR-restriction fragment length polymorphism (RFLP) have been used for genotype the identific...

Aim: Cattle is one of the main sources of food supply chain for humans in most countries. The present study aimed to identify the infection rates for Toxoplasma gondii, Neospora caninum, and Sarcocystis spp. by polymerase chain reaction (PCR) method in native slaughtered cattle in Kashan, central Iran. Materials and Methods: Totally, 159 diaphragm,...

Aims:Staphylococcus aureus is considered a major cause of food poisoning in the world. We aimed to investigate the prevalence of S. aureus isolated from hamburgers in Kashan city. Materials and Methods: In this study, 71 hamburger samples were collected from supermarkets in Kashan from March to July 2017. The samples were examined after dilution in...

Purpose In the current era, cystic echinococcosis (CE), as larval stage of Echinococcus granulosus, is considered as a threat to human health. Scolicidal agents used in the surgery of cysts have different side effects. Therefore, the present study aimed to assess the effects of chitosan nanoparticles containing curcumin (Ch–Cu NPs) on the protoscol...

BACKGROUND: Dicrocoeliasis is one of the commonest parasitic diseases of the bile ducts and gallbladder in a wide range of mammals including ruminants and sometimes human being. The disease is really important in medicine, economy, and veterinary medicine. Annually, slaughter house loses a huge amount because of losing a great deal of valuable prot...

Background and Aims: The aim of this study is to clarify nitric oxide (NO)-production by spleen and the importance of spleen in malaria infection in murine model. Materials and Methods: Thirty outbred NMRI female mice were divided into four groups, Group I: No intervention (Healthy control), Group II: With splenectomy (Healthy test), Group III: No...

Giardiasis has a global distribution and it is a common cause of diarrhea in both children and adults and is transmitted via the fecal-oral route through direct or indirect ingestion of cysts. The laboratory diagnosis of Giardia spp. is mainly based on demonstration of microscopic cyst or trophozoite in stool samples but several immunological-based...

Recurrence of hydatidosis may results from cyst fluid spillage during surgery. To inactivate the cyst content, different scolicidal agents have been introduced. Nevertheless, novel and more effective treatments are needed due to the associated complications. In the current study, we examined the scolicidal effects of gold nanoparticles on Echinococ...

Aim Fasciolosis and dicrocoeliosis are important parasitic diseases worldwide, causing significant financial losses due to decrease in production and viscera condemnation in animals. We performed the current research to assess the epidemiology of these infections and determine their significance from an economic perspective in Arak, Iran. Material...

The most important transmission path of intestinal parasites is the consumption of contaminated water and food. This survey was conducted to determine the prevalence of intestinal parasites among food handlers in Kashan, central Iran. This cross-sectional study was carried on 1018 food handlers who referred to the health centers in order to receive...

Background: Acanthamoeba is one of the mostcommonopportunistic free-living amoebae, with ubiquitous presence in various environmental sources. Pathogenic strains of Acanthamoeba are the causative agents of amoebic keratitisandgranulomatous amoebic encephalitis. Objectives: The aim of the present study was to identify Acanthamoeba genotypes in soil,...

Trichomoniasis, which is caused by Trichomonas vaginalis, is the most common non-viral sexually transmitted infection (STI) in the world including Iran. There were roughly 250 million new cases all over the world in a year. T. vaginalis as an important disease has been associated with HIV (in terms of exposure to sexually transmitted infection, STI...

Introduction: Intestinal parasitic infections are among the most common diseases worldwide and are significant indicators of the health status of communities, especially in developing countries. This study aims to determine the prevalence of intestinal parasites infection in patients referring to Kashan diagnostic laboratories from July 2015 to Aug...

Background: The protozoan Trichomonas vaginalis is a sexually transmitted disease (STD). Metronidazole is a chosen drug for the treatment. This study evaluated the anti trichomonal activity of alcoholic extracts of combination Verbascum thapsus and Ginger officinale. Methods: This experimental study was conducted in the Parasitology Laboratory, Ka...

Background: Intestinal parasites are one of the most important human infections in many tropical and sub-tropical areas. Objectives: The aim of the present study was to determine the prevalence of intestinal parasites and their association with some demographic factors in patients referred to the Ghamar Bani Hashem hospital Khoy, West Azarbaijan pr...

The results indicated that the monthly average of the number of total coliforms in raw sewage and effluent are 3.84 E6 and 7.01E2 respectively and also the fecal Coliform is 2.7 E6 and 4.76E2 MPN/100 ml respectively. Therefore, the overall efficiency of wastewater treatment in the removal of total coliforms, fecal Coliforms and the nematodes eggs a...

Background and Aim: Due to the high prevalence and worldwide distribution of Enterobius vermicularis and its readily transmission among children, parents’ knowledge and health education have an important role in restriction and infection control. This study was performed to evaluate the girl students’ knowledge about transmission, symptoms, and pre...

The prevalence of bovine Sarcocystosis is high in the most regions of the world. It can be a human health problem due to consumption of raw or under cooked hamburgers or other bovine meat products. This study was carried out to investigate the prevalence and species identification of Sarcocystis among of hamburgers, using PCR–RFLP methods in Kashan...

Aims: Toxoplasma gondii is a protozoan parasite and congenital transmission, abortion, and prenatal mortality are major problems of this parasite. This study was carried out to determine the seroprevalence of Toxoplasma infection in the pregnant women, referring to Khoy Public Hospital, Iran, during 2015–2017. Materials and Methods: In this descrip...

Trichomonas vaginalis is a flagellated parasite affecting about 276 million people annually worldwide. Tricomoniasis is associated with different complications in pregnant women and infants. 5'-nitroimidazole derivatives (metronidazole, ornidazole, and tinidazole) are FDA approved drugs recommended for trichomoniasis treatment. Treatment with metro...

Background: One of the most important zoonotic helminths in the world is known as Echinococcus granulosus. Different strains of the E. granulosus have been described based on morphological and molecular characterizations, however, there is limited information regarding the characteristics of the phenotypes and genotypes of E. granulosus in Iran. Me...

Background: Propolis is one of the most potent natural antibiotics. Propolis as an active natural substance is attractive due to its antimicrobial properties. Propolis has been used in folk medicine for centuries. It is known that propolis possesses anti- microbial, antioxidative, anti-ulcer and anti-tumor activities. Therefore, propolis has attrac...

Background: Amebiasis with up to 100 000 human deaths each year is the third cause of human deadly parasitic disease. With regard to the fact that cysteine protease 5 is known to be one of the most important pathogenicity factors of the Entamoeba histolytica and also, CP5 gene has been observed only in E. histolytica, hence we discriminated E. hist...

Introduction: Intestinal parasitic infections (IPIs) are important causes of morbidity and mortality in patients with immunocompromising conditions. Objective: The aim of this study was to determine the prevalence of IPIs in different groups of immunocompromised patients, including hemodialysis patients (HD), renal transplant recipients (RTR), can...

Background: Based on genotyping study of human isolates of Giardia lamblia; humans are mainly infected by two assemblages A and B. The present study was carried out to determine the sub-assemblages of G. lamblia isolated from food handlers referred to Kashan health centers, central Iran, 2015. Methods: In this cross-sectional study, 3653 stool samp...

Objective: Acanthamoeba is one of the most abundant free-living amoebas that is widely distributed in natural and artificial environment resources. Acanthamoeba pathogenic genotypes cause chronic human diseases including amoebic keratitis and granulomatous amoebic encephalitis. The aim of this study was to determine and identify Acanthamoeba genoty...

Background: Trichomoniasis is the most common sexually transmitted protozoan diseases in the worldwide. Metronidazole is the choice drug for trichomoniasis treatment, however, metronidazole resistant Trichomonas vaginalis (T.vaginalis) has been reported. Natural products are the source of most new drugs, and Zingiber officinale (Ginger) is widely u...

Aims: In this study, we examined stool specimen from a 3-year-old domesticated dog, which was referred to a veterinary clinic with clinical signs such as nausea or vomiting, dysentery, cachexia and rash in Mashhad city, northeast of Iran. Patient & Methods: A 3-year-old pet dog was referred to veterinary clinic of Mashhad in February 2016 by sympto...

Toxoplasma gondii is one of the important opportunistic pathogen among solid-organ transplant recipients and hemodialysis patients (HD). This study was aimed to detect toxoplasmosis among 50 renal transplant recipients (RTR), 135 HD and 120 healthy individuals in two cities (Kashan and Qom) that located in the center of Iran, from 2014 to 2015. Ser...

Cutaneous leishmaniasis (CL) is endemic in the northwest of Isfahan province, Iran. Increase in the incidence of the disease in Kashan has made it necessary to find out the best method for diagnosis and molecular characterization of Leishmania species. In the present study, 130 patients suspected to cutaneous leishmaniosis referred to health care c...

Background: Insecticide resistance is one of the serious problems for German cockroach control program. This study was conducted to determine the bendiocarb and Carbaryl resistance mechanisms in German cockroaches using the piperonyl butoxide (PBO). Methods: Bioassay tests were conducted with 4 to 6 different concentrations of both insecticides...

Background: There are scant evidences between giardiasis and enterobiasis with human mal-absorption of micronutrient. Objectives: The aim of the present study was to found out the changes in the serum zinc, copper, magnesium and vitamin B12 levels in schoolchildren infected with Giardia intestinalis and Enterobius vermicularis. Patients and Methods...

Objectives: Physical transmission of microorganisms from hands, surfaces and the environment can contaminate paper currencies since almost every socioeconomic setting commonly hold and transfer paper currencies. Contamination of objects by pathogen microorganisms is the serious concern of public health as transmitting contaminated materials with ha...

Trichomoniasis is a sexually transmitted disease (STD) caused by a tiny parasite called Trichomonas vaginalis. Metronidazole is used as routine treatment of disease. Some reports have confirmed the potential carcinogenic and teratogenic effects of this drug on fetus and indication of drug resistance. Verbascum thapsus belongs to the family of Scorp...

The number of valid of pathogen and non-pathogen species of Entamoeba has continuously increased in human and animals. This review is performed to provide an update list and some summarized information on Entamoeba species, which were identified up to the 2014. We evaluated the Entamoeba genus with a broad systematic review of the literature, books...

Background: Trichomonas vaginalis is a flagellate pathogenic protozoa of human urogenital tract,that infect 170 million new cases through the word annually. Considering to the side effects of metronidazole as common drug to treatment of this disease ,this study was conducted to evaluate thein vitro activity of extract of Allium cepa, Oliveria decum...

Background: This study was conducted to determine acute and chronic toxoplamosis in pregnant women and its complications in newborn. Materials and Methods: In this cohort study, 798 pregnant women were tested for Toxoplasma IgG/ by ELISA. PCR and IgM were performed on 4 newborns of acute and 5 chronic maternal infections; were followed for 1 year....

Introduction: Toxoplasmosis, caused by Toxoplasma gondii, is a protozoan parasitic infection distributed worldwide. Early infection by this protozoa can lead to abortion and congenital toxoplasmosis in pregnant women. This study was conducted to determine the seroprevalence of T. gondii infection among pregnant women referring to Shahid Akbar Abadi...

Objective: To determine the prevalence and economic losses of Fasciola spp. incurred due to liver condemnation from ruminants in Kashan region, center o fi sIroalant efrso amn d2 0c1o2s ttos 2013. Methods: In this cross-sectional study, a total number of 251 325 slaughtered sheep, goats and cinadttules tr(8ia8 l9 3K9a sshheaenp a, b1a5t1t o9i2r4s g...

Background: Cutaneous leishmaniasis (CL) is common and endemic in many areas of Iran, caused by species of a protozoan parasite belonging to the genus Leishmania. There is not any effective vaccine against leishmaniasis; so, therapy is important for prevention and separation of disease. Herbal extract for treatment of CL is cost-effective, applicab...

Introduction: Intestinal parasitic infections are still a healthy problem in many developing countries, although intestinal parasitic infection has reduced in recent years, it is still prevalent in many regions of Iran. This study was carried out in order to determine fauna and prevalence of human intestinal parasites in patients referred to Kashan...

Dear Editor, In Vol.5, No.2, 2012, Jundishapur Journal of Microbiology a paper entitled “A study on prevalence of gastrointestinal parasitic infections in HIV (+) patients referred to Ahvaz Razi Hospital in 2008-2009” was published. We are grateful to Dr Yosefi et al. for his effective paper in this journal. We read this manuscript with a great int...

Many microscopic-based epidemiological surveys on the prevalence of human intestinal pathogenic and nonpathogenic protozoa including intestinal amoeba performed in Iran show a high prevalence of human intestinal amoeba in different parts of Iran. Such epidemiological studies on amoebiasis are confusing, mainly due to recently appreciated distinctio...

Background: Entamoeba histolytica/Entamoeba dispar and Enterobius vermicularis are the major health problems in the developing countries especially in Iran. The prevalence of infection is variable among different social groups in the world. Objectives: Since elderly and mentally retarded are high risk group, the present survey was carried out in or...

Background: Regarding the increasing number of acanthamoebiasis cases in recent decades, investigating the environmental pollution of this amoeba is now a focus of more attention. Surface stagnant water is considered as one of the important sources of human infections. Objective: The aim of this study was isolation and molecular identification of A...

Hydatid disease, caused by larval stage of Echinococcus granulosus, is a common parasitic infection of human and animal. Although liver and lung are the most commonly affected area, hydatid cyst may develop any part of the body. Primary subcutaneous hydatid cyst is extremely rare. We report a case of 54 years old man who presented with palpable mas...

It has been hypothesized that leishmania parasites escape the host defence mechanisms by mimicry of human blood group antigen, conflicting reports have been published. The distribution of blood goup types of human infected with cutaneous leishmaniasis was compared with control subjects. For each patient and control the following data were collected...

Application of solar energy for wastewater treatment has shown to have the least negative effects and costs. This experimental research was carried out in pilot-scale on the effluent of the extended aeration activated sludge wastewater treatment system in Kashan. The plant is located at the Kashan University of Medical Sciences campus and receives...

Background: Entamoeba histolytica/Entamoeba dispar and Enterobius vermicularis are the major health problems in the developing countries especially in Iran. The prevalence of infection is variable among different social groups in the world. Objectives: Since elderly and mentally retarded are high risk group, the present survey was carried out in or...

Cutaneous leishmaniasis is still a health problem in many rural and urban regions of Iran and drug resistance has emerged as a major impediment in the treatment of leishmaniasis. This study aims to determine the drug resistance gene in cutaneous leishmaniasis by PCR in some endemic areas of Iran. Ninety seven samples were collected from ulcers of l...

Liver fluke are common parasites of herbivores in most of Middle East countries including Iran. The choroic infections of this parasite cause biliary liver cirrhosis in cattle, sheep and goats that leads to huge economic losses. This cross-sectional study was carried out to determine the prevalence of fascioliosis and dicrocoelioss in Slaughtered a...

Background: We examined a molecular method with a single-PCR for amplification of a part of CP5 gene enabling us to differentiate the pathogenic species, Entamoeba histolytica, from the non-pathogenic species, E. dispar. Methods: We developed a single PCR method for this purpose. After investigation of GenBank, primer pairs were designed from high...

Trichomoniasis is a worldwide protozoan parasitic disease and metronidazole is a choice drug for its treatment. Because of disease importance in public health and its controversial ideas about the prevalence of drug resistance, this study was carried out. Fifty-two suspected vaginal samples were collected from 2006 to 2007 in Gynecology Maryam Hosp...

The main objective of the present work was to investigate the epidemiology of toxocariosis due to Toxocara cati in stray cats inhabiting the metropolitan region of the city of Tehran, Iran. Furthermore, as the etiological confirmation of this nematode depends on the availability of efficient diagnostic techniques, in this work, Toxocara cati antige...

Introduction and objective: Otomycosis is a fungal infection of external auditory meatus. The acute form of the disease causes secretion and pruritus. The usual prescribed medicines for otomycosis are topical clotrimazole 1%, amphotericin B and otosporin. The aim of the present study was to evaluate the efficacy of treatment with isopropyl alcohol...

Background and the purpose of the study: This study was designed to evaluate the effectiveness of different concentrations of Nanosilver solution against Iranian strain of Leishmania major (MRHO/IR/75/ER) both in vitro and in vivo on BALB/c mice model for the first time. Methods: this is an interventional study which was conducted on the infected m...

Toxocaracati is one of the most important and widespread of the helminth zoonosis. In the present study, helminthosis due to Toxocaracati in 55 stray cats in Tehran was studied by necropsy. In addition, two different diagnostic methods, including serological and coprological tests, for infection with this parasite were compared. The dot-ELISA assay...

Considering the role of parasites in contamination of human beings and domestic animals and lack of information in the region, the present study was performed to investigate the infection status of helminthes and protozoa of stray cats in central Iran. A cross - sectional study was conducted on 113 stray cats trapped from different geographic regio...

The nucleotide sequences of Serine-Rich Entamoeba histolytica Protein (SREHP) gene have already exhibited stable and significant polymorphism in the gene studies. Serine-rich protein is also present and polymorphic in Entamoeba dispar which called SREDP. The polymorphism of the Serine-Rich Entamoeba dispar Protein (SREDP) gene among 8 isolates obta...