Hong-tian Li

Peking University Health Science Center · Department of epidemiology

The association of gestational weight gain (GWG) with perinatal outcomes seems to differ between women with and without gestational diabetes mellitus (GDM). Whether GDM is an effect-modifier of the association has not been verified. This study aimed to assess the modifying effect of GDM on the association of GWG with perinatal outcomes. Data on 12,...

Background: Cesarean delivery vs vaginal delivery was reported to increase the risks of childhood obesity, pneumonia, anemia, and neurobehavioral disorders, but few studies were able to deal with the confounding biases associated with medical conditions indicating cesareans. This prospective cohort study aims to investigate the associations of non...

Cesarean delivery (CD) versus vaginal delivery was reported to increase the risks of childhood obesity, pneumonia, anemia, and neurobehavioral disorders, but few studies were able to deal with the confounding biases associated with medical conditions indicating cesareans. This prospective cohort study aims to investigate the associations of non-med...

Folate status for women during early pregnancy has been investigated, but data for women during mid-pregnancy, late pregnancy, or lactation are sparse or lacking. Between May and July 2014, we conducted a cross-sectional study in 1211 pregnant and lactating women from three representative regions in China. Approximately 135 women were enrolled in e...

[This corrects the article DOI: 10.1016/j.xinn.2020.100028.].

Background: Observational studies have shown promising therapeutic effects of long-pulsed neodymium-doped yttrium aluminum garnet (LP-Nd:YAG) laser on warts. Objective: To evaluate whether LP-Nd:YAG laser was superior to cryotherapy for cutaneous warts. Methods: In this study, 150 adult patients with warts were randomized equally to receive la...

Since the outbreak of Covid-19, many randomized controlled trials have been launched to test the efficacy of promising treatments. These trials will offer great promise for future treatment. However, a public health emergency calls for a balance between gathering sound evidence and granting therapeutic access to promising trial drugs as widely as p...

Background: Screening-based and risk-based strategies are the 2 strategies for preventing group B streptococcus (GBS) diseases in neonates. We aimed to compare the effects of these 2 strategies in reducing the incidence of early-onset GBS sepsis (GBS-EOS) and their effects on the incidence of non-GBS sepsis. Methods: PubMed, Embase, Web of Scien...

Inappropriate cesarean delivery rates pose a risk to the health of women and infants. In 2014, the cesarean delivery rate in China was 34.9%, with geographic variation ranging from greater than 60% in some supercities to less than 10% in some rural areas.

Objective To measure the association of China’s universal two child policy, announced in October 2015, with changes in births and health related birth characteristics. Design National, descriptive before-and-after comparative study. Setting Every county in 28 of 31 provinces of mainland China. Participants Births included in two national databas...

Adequate docosahexaenoic acid (DHA) is essential for the optimal growth and development of the fetus. Maternal DHA content fluctuates during pregnancy. The correlation of DHA content with dietary intake might be varied over the course of pregnancy. We aimed to compare the dietary DHA intake, estimated by a DHA-specific semiquantitative food frequen...

Importance The increasing use of cesarean delivery is an emerging global health issue. Prior estimates of China’s cesarean rate have been based on surveys with limited geographic coverage. Objective To provide updated information about cesarean rates and geographic variation in cesarean use in China. Design, Setting, and Data Sources Descriptive...

Objective: We tested whether melamine nephrotoxicity was exacerbated by urate (a typical component of renal stones in humans) in rats with hyperuricemiainduced by the uricase inhibitor, potassium oxonate (Oxo). Methods: Rats were exposed to melamine or Oxo alone or combinations of melamine (200-400 mg/kg) and Oxo (200-600 mg/kg) for 3 consecutiv...

Few studies have examined docosahexaenoic acid (DHA) in pregnant and lactating women in developing countries like China, where DHA-enriched supplements are increasingly popular. We aimed to assess the DHA status among Chinese pregnant and lactating women residing areas differing in the availability of aquatic products. In total, 1211 women in mid-p...

Cesarean delivery may reduce placental-fetal transfusion and thus increase the risk of early childhood anemia compared with vaginal delivery, but this notion has not been carefully studied in longitudinal cohorts. The aim was to assess the association of cesarean delivery with anemia in infants and children in 2 longitudinal Chinese birth cohorts f...

To prospectively evaluate the health status of infants with exposure to melamine-contaminated milk formula prior to September 2008. The cohort study was conducted in an area close to the manufacturer of Sanlu dairy products. There were three groups (n = 47 each). In September 2008, the exposure group I included infants with exposure to melamine and...

To the Editor In the Clinical Crossroads article on cesarean delivery on maternal request (CDMR), Dr Ecker1 enumerated short- and long-term risks to maternal health, risks for future pregnancies, and short-term health risks to the infant. However, his review did not cover long-term health risks to the infant.This is an important omission. Increasin...

To explore the secular trends of cesarean delivery and cesarean delivery on maternal request(CDMR) among multiparous women who delivered a full-term singleton in Southern China during 1993-2005. The Perinatal Healthcare Surveillance System was established in 21 cities/ counties of 2 Chinese Southern provinces since 1993. A total of 191 058 multipar...

Objectives To assess the impact of caesarean delivery including non-medically indicated maternal request caesarean delivery on childhood overweight. Methods We conducted a prospective investigation of a Chinese birth cohort involving 181380 children, who were born during 1993-1996 to mothers registered in a perinatal care surveillance system and wh...

Introduction: Studies have reported inconsistent results regarding clinical feature and the prognosis status of the affected children in China melamine-contamination event. We summarized available literatures by performing a review and meta-analysis. Methods: Statistical pooling was performed using random-effects model; the sources of heterogene...

To explore the secular trends of cesarean delivery and cesarean delivery on maternal request (CDMR) among primiparous women with singleton pregnancy in Southern and Northern China. The Perinatal Healthcare Surveillance System was established in 26 counties/cities of 3 Chinese provinces since 1993. A total of 1 317 774 primiparous women with singlet...

Herpes zoster (or shingles), an infectious disease caused by reactivation of latent varicella-zoster virus (VZV) in the dorsal root or cranial nerve ganglia, typically manifests as unilateral acute pain accompanied by a vesicular rash. The acute pain and rash usually resolve within 2– 4 weeks without treatment. Postherpetic neuralgia, commonly defi...

Cesarean section births have been steadily increasing over the past decade and have become an epidemic in China. Cesarean delivery on maternal request is a major contributor to this upward trend, and there has been of much concern about its impact on maternal and child health. Most of mothers believe that cesarean delivery on maternal request can i...

Children's behavior is complex and may involve both genetic and environmental influences, [33-37] but it is important to note that assessments of children's behavior should take into account the cultural environment and social content. There is a clear need to establish the use of the ASEBA for Mainland China populations, particularly in order to a...

To study the current status of spontaneous abortion of primigravid women in Jiaxing areas of Zhejiang province of China. We analyzed the data from both perinatal healthcare surveillance program and spontaneous abortion, collected in Jiaxing areas by the Institute of Reproductive and Child Health, Peking University. The study population consisted of...

To determine the association between pregnancy-induced hypertension(PIH) and risk of preterm delivery (PD) and low birth weight (LBW). A prospective cohort was established based on 131 867 women who delivered a singleton baby in seven cities or counties in Zhejiang province, China, during the period of 1995 - 2000. The exposure group included 14 27...