Holger Arndt

Spring Techno GmbH & Co. KG

Gait analysis has evolved significantly during last years due to the great development of the Medical Internet of Things (MIoT) platforms that allow an easy integration of sensors (inertial, magnetic and pressure in our case) to the complex analytics required to compute, not only relevant parameters, but also meaningful indexes. In this paper, we e...

Background: Research efforts to measure the concept of healthy ageing have been diverse and limited to specific populations. This diversity limits the potential to compare healthy ageing across countries and/or populations. In this study, we developed a novel measurement scale of healthy ageing using worldwide cohorts. Methods: In the Ageing Trajec...

We present INforE, a prototype supporting non-expert program- mers in performing optimized, cross-platform, streaming analytics at scale. INforE offers: a) a new extension to the RapidMiner Studio for graphical design of Big streaming Data workflows, (b) a novel optimizer to instruct the execution of workflows across Big Data platforms and clusters...

We investigated the relation between alcohol drinking and healthy ageing by means of a validated health status metric, using individual data from the Ageing Trajectories of Health: Longitudinal Opportunities and Synergies (ATHLOS) project. For the purposes of this study, the ATHLOS harmonised dataset, which includes information from individuals age...

Background: Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people. The aims of this study are to evaluate the temporal variations of pain rates among general populations for the period 1991-2015 and to project 10-year pain rates. Methods: We used the...

Background: Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people, and with increasing trends in general populations. Different risk factors for pain have been identified, but generally from studies with limited samples and a limited number of candidat...

A synergetic understanding of cancer evolution and the effect of combination drug therapies on the disease is the cornerstone for developing effective personalized treatments, which can radically improve patients' well-being and their quality of (work and social) life. By extension, improving the treatment of patients indirectly enhances the qualit...

The Ageing Trajectories of Health – Longitudinal Opportunities and Synergies (ATHLOS) cohort harmonizes existing longitudinal data from 17 international cohort studies. It aims to achieve a better understanding of the impact of ageing on health and to propose timely clinical and public health interventions to optimize and promote healthy ageing....

Background Studies on the effects of sociodemographic factors on health in aging now include the use of statistical models and machine learning. The aim of this study was to evaluate the determinants of health in aging using machine learning methods and to compare the accuracy with traditional methods. Material/Methods The health status of 6,209 a...

Background The use of Cardiovascular Disease (CVD) risk estimation scores in primary prevention has long been established. However, their performance still remains a matter of concern. The aim of this study was to explore the potential of using ML methodologies on CVD prediction, especially compared to established risk tool, the HellenicSCORE. Met...

Background Aging is a multidimensional process with a remarkable inter-individual variability. This study is focused on identifying groups of population with similar aging patterns, and to define the health trajectories of these groups. Socio-demographic and health determinants of these trajectories are also identified. Methods Data from the Engli...

One of the aims of the ATHLOS project is to develop a single metric of healthy ageing. Using as a paradigm the ELSA study – English Longitudinal Study on Aging (n= 11,906 participants, entry 1998–2001, last follow up 2011–12, 6 waves) - and applying the Item Response Theory (IRT) approach and multi-level Factor Analyses the metric of healthy aging...

A most challenging task for scientists that are involved in the study of ageing is the development of a measure to quantify health status across populations and over time. In the present study, a Bayesian multilevel Item Response Theory approach is used to create a health score that can be compared across different waves in a longitudinal study, us...

Constant monitoring of gait in real life conditions is considered the best way to assess Fall Risk Index (FRI) since most falls happen out of the ideal conditions in which clinicians are currently analyzing the patient's behavior. This paper presents the WIISEL platform and results obtained through the use of the first full-wireless insole devices...

This paper presents the final results and future projection of the European project WIISEL (Wireless Insole for Independent and Safe Elderly Living), that reached to build the first full-wireless insole (that include both wireless communication and wireless charging). These insoles provide a new set of non-invasive tools that can be used either at...

Practical guide on the setup and coding of financial trading systems with examples, written in Tradestation Easy Language. German.