Ho-Hsiung Lin

Ho-Hsiung Lin
National Taiwan University | NTU · Department of Pathology

About

249
Publications
18,090
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7,361
Citations
Additional affiliations
August 1986 - present
National Taiwan University
Position
  • Professor
Description
  • 1. I was promoted as a professor at this department in August 1996.
April 1979 - July 1986
The University of Tokyo, Japan
Position
  • Resident and Visiting Staff
Description
  • 1. I got PhD degree of Department of Obstetrics and Gynecology, School of Medicine, The University of Tokyo, Japan in April 1986.
July 1977 - July 1978
National Taiwan University
Position
  • Professor (Assistant)

Publications

Publications (249)
Article
Objective To compare the cesarean section (CS) rates of obstetricians with a preference of labor induction at early versus late gestational age. Material and methods Medical records of women who were low risk, nulliparous, singleton pregnancy, and >37 weeks and delivered their babies, were reviewed. Obstetricians, who preferred labor induction at<...
Article
Full-text available
The study aims to elucidate the impact of mirabegron versus solifenacin on autonomic function and peripheral arterial conditions in women with overactive bladder syndrome (OAB). All consecutive women with OAB were randomized to receive 12 weeks of mirabegron 25 mg or solifenacin 5 mg once per day. Heart rate variability, cardio-ankle vascular index...
Article
Purpose To evaluate the changes in clinical outcome and urodynamic parameters after tailored anterior transvaginal mesh (ATVM) surgeries in a mid-term follow-up. Methods Between November 2011 and December 2015, women with ≥stage II pelvic organ prolapse (POP) who underwent ATVM surgeries were retrospectively reviewed. The data-reviewing timeframe...
Article
Clinical outcome of laparoscopic myomectomy with the use of Quill™ suture seems similar to that with V‐Loc™ suture.
Article
Objective The clinical presentation of non-gastric GISTs might mimic adnexal cancer, and non-gastric GIST might be managed and treated by gynecologists. Knowledge of the clinical outcomes of women with non-gastric gastrointestinal stromal tumors (GISTs) is important. Our aim is to elucidate the factors affecting the clinical outcomes of women with...
Article
Full-text available
PurposeTo describe the prevalence and predictors of nocturnal polyuria (NP) in women with overactive bladder syndrome (OAB).Methods Between July 2009 and January 2018, women with OAB were enrolled. NP was defined when the nocturnal polyuria index (NPI) (nighttime voided volume over 24-h voided volume) was > 33% (NPI33) in women ≥ 65 years-old and >...
Article
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Background and Objectives: To identify the predictors of clinical outcomes in women with pelvic organ prolapse (POP) who underwent transvaginal reconstruction surgery, especially with transobturator mesh fixation or sacrospinous mesh fixation. Materials and Methods: All women with POP who underwent transvaginal reconstruction surgery, especially wi...
Article
Introduction and hypothesisThis study examined the associated factors (i.e., obstetric and maternal-newborn factors) related to cumulative incidence of urinary incontinence and changes in urinary incontinence during pregnancy and the first year postpartum.Methods This prospective, longitudinal, within-subject study included 501 women who completed...
Article
Objectives To determine predictive factors for the cure of or persisting or de novo overactive bladder syndrome (OAB) after a mid-urethral sling procedure (MUS) for women with stress urinary incontinence (SUI), especially for menopausal women. Study Design All women who had consecutively received MUS for SUI between January 2008 and July 2019 in a...
Article
Objective To evaluate the feasibility and effectiveness of robotic/laparoscopic repair of cesarean scar defects or cesarean scar pregnancies with a uterine sound. Materials and methods All consecutive women with cesarean scar defects or cesarean scar pregnancies who underwent robotic/laparoscopic repair with a bent uterine sound guidance were revi...
Article
Introduction and hypothesisWe examined obstetric and maternal-newborn factors and UI history for stress urinary incontinence (UI) and urge UI during pregnancy and the first year postpartum.Methods This prospective cohort study included 1447 pregnant women who underwent prenatal examinations and completed an Incontinence Questionnaire-Urinary Incont...
Article
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The repeatability of the 20-min pad test has not been reported. The aim of this study was to evaluate the test–retest reliability of the 20-min pad test in women with urodynamic stress incontinence. Among 89 enrolled women, 67 (75%) women were diagnosed with urodynamic stress incontinence and were examined in this study. The mean strong-desire volu...
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Background: to elucidate the predictors of progression-free survival (PFS) and overall survival (OS) in high-risk endometrial cancer patients. Methods: the medical records of all consecutivewomen with high-risk endometrial cancer were reviewed. Results: among 92 high-risk endometrial cancer patients, 30 women experienced recurrence, and 21 women di...
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Purpose To evaluate the prevalence of detrusor underactivity (DU) and bladder outlet obstruction (BOO) in women with high-grade cystocele and the impacts of cystocele repair. Methods Between November 2010 and September 2018, women with ≥stage II cystocele were included. DU (detrusor pressure at maximum flow rate (PdetQmax) < 20 cmH2O, maximum flow...
Article
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Background: We aimed to compare the clinical outcomes between intraperitoneal chemotherapy and dose-dense chemotherapy for the frontline treatment of advanced ovarian, fallopian tube and primary peritoneal cancer in women not receiving bevacizumab. Methods: All consecutive women with stage II~IV cancer treated with either frontline intraperitoneal...
Article
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The pathophysiology of female overactive bleeder syndrome (OAB) remains undetermined. Our aim is to elucidate the role of vacularization and overall perfusion of the bladder wall in women with OAB. Between 2010 and 2016, women with OAB and the asymptomatic controls were enrolled. Women with OAB were treated with tolterodine. Women with OAB (n = 40)...
Article
Full-text available
Purpose: The Q-tip test is used to measure urethral hypermobility and can predict surgical outcomes. However, certain factors may affect the reliability of this test. Our aim was to identify independent clinical and urodynamic predictors of the results of the Q-tip test. Methods: Between January 2014 and June 2019, 176 consecutive women with low...
Article
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Background/purpose Factors affecting the anti-incontinence efficacy of a tailored anterior transvaginal mesh (ATVM) surgery are undetermined. Thus, our aim was to investigate predictors for anti-incontinence efficacy of this ATVM surgery. Methods Medical records of women with pelvic organ prolapse and concomitant evident or occult urodynamic stres...
Preprint
Background: Knowledge of the clinical outcome of women with non-gastric gastrointestinal stromal tumors (GISTs) is important for preoperative and postoperative consultation, especially for gynecologic oncologist. The aim of this study is to elucidate the factors affecting the clinical outcome of women with non-gastric GISTs. Methods: Between Januar...
Article
Full-text available
Taiwanese women frequently receive Shenghua decoction treatment for uterus involution. However, prolonged Shenghua decoction treatment can be detrimental. Herein, we report the case of a woman with disastrous postpartum hemorrhage after prolonged Shenghua decoction treatment. A 36-year-old woman underwent scheduled cesarean delivery due to cephalop...
Article
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Purpose: To evaluate the post-hysterectomy vault prolapse (PHVP) rates performed using different methods of vaginal total hysterectomy (VTH). Methods: A total of 251 women who underwent VTH with/without concomitant surgeries between January 1986 and December 2001 in a tertiary center. Thirty-eight women were excluded due to not only a vaginal ap...
Article
Full-text available
Fluid overload is a potential complication of hysteroscopic procedures with the possibility of dangerous electrolyte changes. This prospective randomized controlled trial aimed to compare perioperative outcomes and changes in electrolytes after hysteroscopic procedures between the manual infusion (MI) and the pump infusion (PI) methods for distendi...
Article
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Background/purpose: The most suitable surgical technique for pelvic organ prolapse (POP) remains undetermined. The aim of this study was to compare clinical outcomes of the tailored transvaginal mesh (TVM) surgery and vaginal native tissue repair (NTR) surgery for POP. Methods: Between November 2011 and August 2014, medical records of 339 women...
Article
Objectives: The aim of this study is to compare the re-treatment probabilities after a 3-month versus a 6-month course of antimuscarinic treatment for women with overactive bladder syndrome (OAB). Study design: A prospective randomized controlled study. Main outcome measures: Between-group differences in the probability of re-treatment for OAB...
Article
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Purpose To identify factors predicting the presence of overactive bladder syndrome (OAB)-wet, compared with OAB-dry. Methods Between September 2007 and September 2013, the medical records of 623 women with OAB who completed a 3-day bladder diary and underwent urodynamic studies in a medical center were retrospectively reviewed. OAB-wet was diagnos...
Article
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Background: Lymphoceles could represent a detrimental complication after retroperitoneal lymph node dissection. Our aim was to elucidate predictors of lymphoceles. Methods: Between 2011 and 2017, medical records of consecutive women who underwent laparotomic retroperitoneal lymph node dissection for FIGO stage I or II gynecologic cancer were review...
Article
Background: The ideal surgical procedure for interstitial pregnancy remains undetermined. The aim of this study was to assess whether surgical method is a factor in predicting subsequent pregnancy in women with interstitial pregnancy who underwent laparoscopic cornuostomy or laparoscopic wedge resection. Methods: Medical records of all women wit...
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Full-text available
Objective To assess the impact of the transobturator mid-urethral sling (MUS) procedure on female sexual function and their partners’ sexual activity. Materials and methods Sexually active women with stress urinary incontinence who underwent a transobturator MUS procedure at the Department of Obstetrics and Gynecology of two medical centers were p...
Article
Study objective: To identify factors predictive of persistent ectopic pregnancy (PEP) in women who have undergone laparoscopic salpingostomy or salpingotomy for tubal pregnancy. Design: Retrospective cohort study (Canadian Task Force classification II-2). Setting: Tertiary referral center. Patients: Ninety-nine women who underwent laparoscop...
Article
Full-text available
Objective To elucidate whether robotic assisted laparoscopic myomectomy (RALM) with barbed sutures is superior to traditional laparoscopic myomectomy (TLM) with barbed sutures. Material and methods Medical records of all women with symptomatic uterine myomas who underwent RALM with barbed sutures or TLM with barbed sutures were reviewed. The patie...
Article
Objective: To identify factors predicting cervical elongation in women with uterine prolapse. Study design: The medical records of women with uterine prolapse who underwent vaginal hysterectomy were reviewed. Multivariable logistic regression analysis was performed to identify predictors of cervical elongation. Results: Of 295 women with uteri...
Article
Background: The association between sexual function and depression has yet to be examined in a prospective cohort study with prolonged postpartum follow-up. Aim: We investigated whether sexual dysfunction predicted depressive symptoms during the 24-month postpartum period and examined the influence of obstetric factors. Methods: This prospecti...
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This retrospective study is aimed to present videourodynamic findings of women with symptoms of voiding dysfunction in a medical center. Of 1914 women, the diagnoses included bladder outlet obstruction (BOO, n = 810, 42.3%), bladder dysfunction (n = 1,048, 54.8%) and normal tracings (n = 56, 2.9%). Anatomic BOO (n = 49) included cystocele (n = 19)...
Article
Aim: We aimed to clarify the impact of night-time dosing with tolterodine extended release (ER) on nocturia. Methods: The bladder diaries, urodynamic studies, and medical records of female patients with overactive bladder syndrome who were diagnosed between January 2005 and December 2015, and treated with tolterodine ER 4 mg once per day (night-...
Article
The aim of this study was to evaluate the efficacy and feasibility of a novel pusher device for performing extracorporeal knot tying. Each of the 3 laparoscopists randomly performed 10 device-assisted double sheet bends (the device group), ten 4s modified Roeder sliding knots (the sliding group), and 10 laparoscopic traditional extracorporeal stati...
Article
Objectives: The impact of mirabegron on clinical outcome and urodynamic parameters may be important for clinical practice. Thus, the aim of this study was to compare the clinical outcomes and urodynamic effects of mirabegron (Betmiga 50 mg) versus tolterodine (Detrusitol ER 4 mg) treatment for women with overactive bladder syndrome (OAB). Methods...
Article
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Objective: Management of cornual gestational trophoblastic neoplasia (GTN) has never been reported. Here, we describe the first case of cornual GTN. Case Report: A 32-year-old woman was diagnosed with left cornual GTN after evacuation of a complete mole. Laparoscopic cornuostomy was performed with intramural vasopression injection and barbed suture...
Article
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Objective: Previous studies evaluating the situation-background-assessment-recommendation (SBAR) have been shown to increase effective nurse–physician communication and collaboration. The purpose of this study is to evaluate the impact of the SBAR technique on safety attitudes in the obstetrics department. Materials and Methods: This study implemen...
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Ovarian cancer is the most lethal of the gynecologic malignancies. N-acetylgalactosaminyltransferase 6 (GALNT6), an enzyme that mediates the initial step of mucin type-O glycosylation, has been reported to regulate mammary carcinogenesis. However, the expression and role of GALNT6 in ovarian cancer are still unclear. Here we showed that high GALNT6...
Article
Full-text available
The aim of this study was to identify factors predicting large post-void residual (PVR) (defined as ≥200 mL), an important unsolved problem, after an intravesical injection of onabotulinumtoxinA in patients with overactive bladder syndrome. The data showed that 133 of 290 patients had a large PVR after treatment. Multivariate analysis found that th...
Article
Introduction and hypothesisThe impact of the IncontiLaseTM procedure on lower urinary tract symptoms (LUTS) remains unclear. Our aim was to evaluate the effects of the IncontiLaseTM procedure for urodynamic stress incontinence (USI). Methods All consecutive women with USI prospectively underwent the IncontiLaseTM procedure. Urodynamic studies, pad...
Article
Objective: The aim of the study was to investigate predictive factors of the need for persistent antimuscarinic therapy or re-treatment (PR) after discontinuation of antimuscarinic therapy for women with overactive bladder syndrome (OAB). Methods: All consecutive OAB women were enrolled in a prospective cohort study, and treated with solifenacin...
Article
Full-text available
Objective: Many countries have noted a substantial increase in the cesarean section rate (CSR). Several methods for lowering the CSR have been described. Understanding the impact of clinical audits on the CSR may aid in lowering CSR. Thus, our aim is to elucidate the effect of clinical audits on the CSR. Materials and Methods: We retrospectively an...
Article
Objectives: Details on the therapeutic effects of long-term antimuscarinic therapy have not been reported. Thus, the aim of this study is to evaluate the detailed long-term therapeutic effect of antimuscarinic therapy. Methods: All consecutive patients who visited the urologic outpatient clinics of a medical center for treatment of overactive bl...
Article
Aim: To investigate the efficacy and urodynamic effects of baclofen in women with functional bladder outlet obstruction. Methods: Between January 2011 and December 2012, women who underwent baclofen treatment for functional bladder outlet obstruction, defined as <15 mL/s maximum flow rate and >20 cmH2 O detrusor pressure at maximum flow rate, bu...
Article
Full-text available
Objectives: To analyze the predictors of therapeutic efficacy after intravesical botulinum toxin A injection for overactive bladder syndrome (OAB) refractory to antimuscarinic therapy. Methods: All consecutively OAB patients, who visited the urologic outpatient clinics of a medical center and refractory to antimuscarinic treatment, were prospect...
Data
Raw data of this study. (XLS)
Data
The study record detail of the clinical trial. (PDF)
Article
Full-text available
Objective . To evaluate the clinical outcomes and urodynamic effects of tailored anterior transvaginal mesh surgery (ATVM) and tailored posterior transvaginal mesh surgery (PTVM). Methods . We developed ATVM for the simultaneous correction of cystocele and stress urinary incontinence and PTVM for the simultaneous correction of enterocoele, uterine...
Article
Objective: Mucin (MUC) 20 has recently been implicated to play a role in human carcinogenesis. However, the role of MUC20 in epithelial ovarian cancer (EOC) remains to be elucidated. Methods: MUC20 expression was assessed in tissue microarray and tumor specimens of EOC patients by immunohistochemistry. Effects of MUC20 on cell viability, adhesio...
Article
Full-text available
Objectives: To determine the factors influencing the abortion interval (AI) for medical termination of second-trimester pregnancy using misoprostol. Materials and methods: All patients who were admitted for second-trimester pregnancy termination between January 2008 and August 2013 were reviewed. Those who received either 200 μg or 400 μg of pri...
Article
Full-text available
Purpose: To determine the duration of antimuscarinic therapy for overactive bladder syndrome (OAB) appropriate for assessment of the efficacy of treatment, and to evaluate the possible predictive factors for response to therapy. Methods: All OAB patients who visited a urology outpatient clinic of a tertiary referral center and who were prescribe...
Article
Full-text available
Objective: Mirabegron, a β3-adrenoceptor agonist, has been shown to be effective and safe in the treatment of overactive bladder (OAB). The aim of this study was to assess the efficacy and safety of mirabegron (50 mg) versus placebo in Taiwanese patients with OAB. Materials and patients: This was a multicenter, randomized, double-blind, parallel-gr...
Article
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Article
Primary ovarian carcinoid tumors are rare entities, they may appear with other teratomatous components, and can be often being mistaken as part of mature cystic teratomas. Consistent with their rarity and low incidence, imaging clues that could have led to suspicion of this tumor are not well-documented. Herein, the authors present a rare case of p...
Article
To examine changes in health-related quality of life throughout the course of pregnancy and among three pairs of consecutive periods (pre-pregnancy to early pregnancy, early to middle pregnancy and middle to late pregnancy), as well as to identify associated obstetric factors during the entire period of pregnancy. Only sparse data are available con...
Article
Aims: To analyze the predictors of therapeutic success after solifenacin treatment. Methods: Between January 2008 and December 2011, all patients with overactive bladder syndrome (OAB) who consecutively visited the urologic outpatient clinics of a medical center were prospectively enrolled. All enrolled patients received 5 mg solifenacin once a...
Article
Symptomatic uterine diverticula are rare and, to our knowledge, have never been reported as a cause of postpartum hemorrhage. A 35-year-old woman presented with severe vaginal bleeding on the 47th day after a cesarean section. She had received endometrial curettage due to postpartum hemorrhage a few days earlier in another local hospital. Transvagi...
Article
To examine the association between vaginal or cesarean delivery and urinary incontinence (UI) and identify the trend in the change in UI within the first 12 months postpartum. This was a prospective longitudinal study of 330 of 749 women who completed a UI questionnaire and a personal characteristics questionnaire over five visits in a medical cent...