Hisila Santacruz

• University of Sonora

Se realizaron actividades biológicas de una fracción aislada del músculo de Litopenaeus stylirostris, la cual contiene un nuevo compuesto bioactivo derivado del alcaloide indolocarbazol, el ácido eicosapentaenoico y el dioctil ftalato. Se estudió la actividad eliminadora de especies reactivas de nitrógeno (ERN), la inhibición de la producción de óx...

Background Cathepsin D is a lysosomal enzyme that plays a critical role in the process of protein catabolism. In marine organisms, research has primarily concentrated on the identification of the enzyme. However, in crustaceans and molluscs, it is known to have digestive functions, as it is the sole enzyme responsible for protein degradation at ext...

Background: Polymeric electrospun mats have been used as scaffolds in tissue engineering for the development of novel materials due to its characteristics. The usage of synthetic materials has gone in decline due to environmental problems associated with their synthesis and waste disposal. Biomaterials such as biopolymers have been used recently d...

Mutations are the result of effects produced by mutagenic agents, which may be responsible for the generation of chronic-degenerative diseases such as cancer. The aim of this work was to detect and characterize compounds with antimutagenic activity in white shrimp (Litopenaeus vannamei) cephalothorax. A serial extraction was carried out where diffe...

This research outlines the fabrication of polymeric membranes and films of poly(lactic acid) (PLA), prepared via electrospinning and extrusion, respectively. These materials were subsequently coated with polyaniline (PANi) by using the in situ chemical polymerization technique. Scanning electron microscopy micrographs revealed that the best coating...

Histamine(β-imidazolylethylamine) (His) is a biogenic amine. It is an important mediator involved in various physiological and pathological processes, including neurotransmission and numerous brain functions, secretion of some hormones,regulation of gastrointestinal, circulatory functions, and inflammatory reactions. However, a high level of histam...

El interés por instrumentos analíticos portables que permitan la detección de metales al alcance de más usuarios ha crecido en los últimos años. Los teléfonos inteligentes se han convertido en laboratorios portátiles. La Química Analítica encontró en los teléfonos una oportunidad para detectar y cuantificar diferentes analitos en tiempo y espacio r...

The interest in portable analytical instruments that allow metal detection available to more users has grown recently. Smartphones have become portable laboratories. Analytical chemistry has found in phones an opportunity to detect and quantify different analytes in real time and space without the need of developing laboratory analysis (an example...

Conductive polymers, such as polypyrrole and polyaniline, have been extensively studied for their notable intrinsic electronic and ionic conductivities, rendering them suitable for a range of diverse applications. In this study, in situ chemical polymerization was employed to coat extruded PLA films with PPy and PANi. Morphological analysis reveals...

The properties of hydroxyapatite (HAp) obtained from tilapia (Oreochromis niloticus) bones and its potential use as a dye adsorbent using methyl orange (MO) as a model dye were evaluated. HAp was produced by the calcination of dried tilapia bones at 900 °C for 4 h. Then, HAp was characterized using thermogravimetric (TGA) and differential thermogra...

Herein, a synthesis method for obtaining lead iodide through chemical bath deposition, a type of chemical solution deposition without the use of organic solvents, is presented; the process consists of three stages. In the first stage, tin hydroxide films are produced which act as a seed layer allowing for a better adherence of the film that is to b...

This research aimed to chemically synthesize and evaluate the antiproliferative and anti-inflammatory potential of ozopromide (OPC), a novel compound recently isolated from O. vulgaris ink. After chemical synthesis, OPC structural characterization was confirmed by COSY2D, FTIR, and C-/H-NMR. OPC inhibited the growth of human breast (MDA-MB-231), pr...

The demand for jellyfish is growing worldwide, especially due to their high nutraceutical value. In this study, the extraction and characterization of crude gelatin from the brown cannonball jellyfish (Stomolophus meleagris), which is periodically found in large volumes on the American Pacific coasts, were carried out. The crude gelatin obtained by...

Pepsin-soluble collagen (PSC) from the skin of Nile tilapia (Oreochromis niloticus) was used for the obtention of collagen scaffolds, and their structural and physico-chemical properties were described. The PSC extraction yield was 18.3%, and the type I collagen was identified from it; the PSC scaffolds were successfully elaborated by electrospinni...

Betaine aldehyde dehydrogenase (BADH EC 1.2.1.8) catalyzes the irreversible oxidation of betaine aldehyde to glycine betaine using NAD⁺ as a coenzyme. Incubation of porcine kidney BADH (pkBADH) with NAD⁺ decreases the catalytic cysteine (C288) reactivity. Potassium ion increases the pkBADH affinity by the coenzyme. This work aimed to analyze pkBADH...

Chitosan (85% deacetylated, viscosity > 400 MPa, and molecular weight of 570.3 kDa)/squid gelatin hydrolysates (SGH) were prepared by incorporating SGHs (10%, 20%, and 40%) into chitosan films. SGH were obtained from squid skin gelatin by hydrolysis with Alcalase. The effects of adding SGH on the physical, chemical structure, mechanical, degradabil...

Significant opportunities exist in the use of seafood by-products to create new beneficial products. Moreover, cephalopod skin is a good source of bioactive compounds. The present study compares the chemical structure properties and antioxidant activity of pigments extracted from the skin of Octopus vulgaris (OVS) and Dosidicus gigas (DGS) with met...

Cancer is a noncommunicable disease of rising worldwide concern. Marine food products such as Octopus vulgaris ink (OI) could be sources of compounds addressing these concerns. This study aimed to evaluate the antimutagenic, cytoprotective, antiproliferative, proapoptotic, and antioxidant capacity of OI extracts on human cancer cell lines (22Rv1, H...

El libro Química Analítica II. Manual de Laboratorio, tiene como finalidad facilitar el desarrollo del programa actual de esta asignatura que se impar- te en el Departamento de Ciencias Químico Biológicas de la Universidad de Sonora; asimismo, se puede utilizar en asignaturas donde se lleve a cabo análisis químico por métodos espectroscópicos en ot...

Four tubular membranes based on PLA and gelatin with different arrangements (PLA, gelatin, PLA-gelatin Blend and PLA/gelatin Core/Shell) were prepared by the electrospinning technique, the gelatin within the materials was crosslinked with genipin and all the meshes were characterized by SEM, ATR-FTIR, TGA, DSC, XRD and mechanical tests, also a viab...

Cation–π interactions between molecules and graphene are known to have a profound effect on the properties of the molecule/graphene nanohybrids and motivate this study to quantify the attachment of the rhodamine 6G (R6G) dye molecules on graphene and the photocarrier transfer channel formed across the R6G/graphene interface. By increasing the R6G a...

To perform improvements in food science, it is fundamental to understand the physicochemical properties of proteins since their interaction with other macromolecules plays an essential role in food systems. Collagen and paramyosin help in the maintenance of the matrix structure cells, the textural behaviour and the technical functionality of the pr...

The oxidative stress damage on cells is an example of roles in the pathogenesis of different degenerative diseases and the search of compounds that can slow this oxidation is continuous. The aim of this work was to obtain bioactive fractions from wild shrimp (Litopenaeus stylirostris) muscle, in order to evaluate their protective capacity and chemo...

This study investigated the performance of chitosan based films with added, high‐intensity ultrasound‐pulsed, gelatins (42, 52, 71 and 84 W cm⁻²). The mechanical, structural, chemical and antioxidant properties were investigated, to evaluate the potential of ultrasound as a technique to improve film properties. The tensile strength and elastic modu...

Ultrasonic pulses are considered green technology for the improvement of the functional properties of proteins. In this study, four high-intensity ultrasound pulse treatments (ultrasound-pulsed gelatin (UPG)-42, UPG-52, UPG-71, UPG-84, and non-pulsed control gelatin (CG)) were applied to tilapia (Oreochromis niloticus) skin gelatin in order to stud...

Marine bioactive compounds have been found in very different sources and exert a very vast array of activities. Squid skin, normally considered a discard, is a source of bioactive compounds such as pigments. Recovering these compounds is a potential means of valorizing seafood byproducts. Until now, the structure and molecular properties of the bio...

Las características físicas y químicas de las gónadas de erizo S. franciscanus fueron estudiadas usando métodos destructivos y no destructivos. Los organismos fueron recolectados en San Carlos, Nuevo Guaymas y procesados para ser evaluados. Se determinó la composición proximal de las gónadas obteniéndose el contenido de proteínas, lípidos, cenizas...

Background: Cathepsin D is a lysosomal enzyme that is found in all organisms acting in protein turnover, in humans it is present in some types of carcinomas, and it has a high activity in Parkinson's disease and a low activity in Alzheimer disease. In marine organisms, most of the research has been limited to corroborate the presence of this enzym...

Foodborne diseases have increased, and with it, the interest to discover new natural antimicrobials; the use of aromatic plants, due to the extraction and use of the essential oil (EO), are widely studied and with great biological activity. However, studies with hydrosols (HS) from aromatic plants are limited. The aim in this study was to evaluate...

El presente trabajo reporta la síntesis de un nuevo sensor fluorescente de cadena abierta tipo biscromofórico con grupos éter y aminos como unidades receptoras y naftaleno como unidad indicadora (L1), y la síntesis del ligante (M1) por el método de síntesis orgánica en fase sólida (SOFS) soportado en resina de Merrifield el cual presenta una estruc...