Hilary Curtis

This audit assessed adherence to standards specified in the BASHH national guidance for management of infection with Neisseria gonorrhoeae (2018). All UK GUM/Integrated Sexual Health Services (Level 3 STI services) were invited to complete a brief survey of clinic service arrangements and case note review of the 40 individuals per clinic diagnosed...

Objectives We aimed to describe clinical policies for the management of people with HIV/hepatitis C virus (HCV) coinfection and to audit routine monitoring and assessment of people with HIV/HCV coinfection attending UK HIV care. Methods This was a clinic survey and retrospective case‐note review. HIV clinics in the UK participated in the audit fro...

Background BASHH/MEDFASH (Medical Foundation for HIV and Sexual Health) Standards for the Management of Sexual Health Services 20141 set out a number of recommendations regarding time between contacting a service to being seen, time to receiving results, and time to treatment. This audit investigated if UK practice is compliant with BASHH standards...

HIV partner notification (PN) is a highly effective strategy to identify people living with undiagnosed HIV infection. This national audit of HIV PN is against the 2015 British Association of Sexual Health and HIV (BASHH)/British HIV Association (BHIVA)/Society of Sexual Health Advisers (SHAA)/National AIDS Trust (NAT) HIV PN standards, developed i...

The British HIV Association recommends that new diagnoses be reviewed by an HIV specialist within two weeks. NHS England outcome measures include the proportion of new diagnoses commencing antiretroviral therapy (ART) within 91 days. We aimed to review the extent to which these recommendations were followed, to explore the topics discussed with new...

Objectives The aim of the study was to describe a UK‐wide process to assess adherence to guidelines for the routine investigation and monitoring of HIV‐positive adults aged ≥ 50 years and provide clinical services with individual feedback to support improvement in quality of care. Methods The British HIV Association (BHIVA) invited HIV clinical ca...

The revised British Association of Sexual Health and HIV UK guidelines on the management of syphilis were published in 2015 and this audit measures performance against those standards and recommendations. Although not included in the guideline recommendations, an exploratory question on clinics’ HIV testing policy was also included. The audit was c...

Late HIV diagnosis is associated with significant mortality in people living with HIV (PLWH) and high numbers of missed opportunities (MO) for earlier testing have been identified. A pilot of a national late diagnosis review process (LDRP) was undertaken in 15 HIV services evaluating the feasibility of LDRP implementation, as a patient safety initi...

Findings from a national pilot process for reviewing very late HIV diagnoses in England and Wales

Objectives The aim of this national audit was to assess adherence of services providing HIV care in the UK to national standards and guidelines regarding psychological support and the assessment of alcohol and recreational drug use (including chemsex drugs) in people living with HIV (PLWH). Methods Participating sites completed a survey of their s...

Objectives Late diagnosis of HIV continues to be associated with high levels of morbidity and mortality. We sought to determine the processes HIV services use to review newly diagnosed individuals with advanced HIV infection and the outcomes of these processes. Methods UK specialist HIV services were invited to participate in a clinical audit compr...

This national audit of 142 clinics demonstrated that the majority of clinics surveyed had policies and agreed clinical practice for alcohol and recreational drug enquiry, as well as documentation of HIV test refusal, although this was not the case in 24% of clinics as regards alcohol usage, 21% of clinics as regards recreational drugs use and 43% o...

This national audit demonstrated discrepancies between actual practice and that indicated by clinic policies following enquiry about alcohol, recreational drugs and chemsex use. Clinics were more likely to enquire about risk behaviour if this was clinic policy or routine practice. Previous testing was the most common reason for refusing HIV testing...

Background The clinical care of people living with HIV changed fundamentally as a result of the development of effective antiretroviral therapy (ART). HIV infection is now a long-term treatable condition. We report a national audit to assess adherence to British HIV Association guidelines for the routine investigation and monitoring of adult HIV-1-...

Background Feedback tools for clinical audit data that compare site-specific results to average performance over all sites can be useful for quality improvement. Proposed tools should be simple and clearly benchmark the site’s performance, so that a relevant action plan can be directly implemented to improve patient care services. We aimed to devel...

Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to reduce risk has been developed. This project aims to review UK management of HIV in pregnancy as part of the British HIV Association (BHIVA) audit programme. Methods The National Study...

Objectives Partner notification (PN) is a key public health intervention in the control of STIs. Data regarding its clinical effectiveness in the context of HIV are lacking. We sought to audit HIV PN outcomes across the UK. Methods All UK sexual health and HIV services were invited to participate. Clinical audit consisted of retrospective case-not...

Background: Regular clinical care is important for the well-being of people with HIV. We sought to audit and describe the characteristics of adults with diagnosed HIV infection not reported to be attending for clinical care in the UK. Methods: Public Health England (PHE) provided clinics with lists of patients diagnosed or seen for specialist HI...

Background: UK National Guidelines for HIV testing were published in 2008 by the British HIV Association (BHIVA), British Association of Sexual Health and HIV (BASHH) and the British Infection Association (BIA). The guidelines identify 11 AIDS-defining conditions (ADC) and 37 clinical indicator diseases (CID) for which HIV testing is recommended....

The aim of the 2010 BHIVA audit was to assess the impact of the 2008 UK HIV testing guidelines on clinical practice. Here, we report one aspect of the audit comprising a survey of local testing policy and practice at centres providing adult HIV services across the UK. Selected recommendations from the 2008 national HIV testing guidelines were asses...

The late diagnosis of HIV in patients across the UK is an increasing problem. Here, we report on a retrospective case-notes audit carried out to assess the impact of the 2008 UK HIV testing guidelines on clinical practice and identify missed opportunities for HIV testing. The audit was carried out in 2010 and focussed on patients with newly diagnos...

This audit aims to compare UK management of tuberculosis (TB)/HIV co-infection with recommended practice and to describe local care arrangements. Services providing HIV care were invited to complete a survey of care arrangements and to review case notes of HIV positive patients aged over 16 who started therapy for active TB between October 2007 and...

The aim of this work was to survey current service provision and adherence to the British HIV Association (BHIVA) guidelines for the management of HIV and hepatitis B/C co-infected patients in the UK. Sites were invited to complete a survey of local care arrangements for co-infected patients. A case-note audit of all co-infected attendees during a...

This 2007 cross-sectional survey is illustrative of UK HIV hospitalization patterns. Data were received for 255 inpatients of whom 43.9% had AIDS-defining illnesses (ADIs). A total of 56.3% had CD4 counts <200 mm(3) and 17% were diagnosed with HIV on their current admission. In those diagnosed for >3 months with CD4 < 200/mm(3) (90/188), 47% were n...

The aim of this work was to audit the extent to which routine HIV care in the UK conforms with British HIV Association (BHIVA) guidelines and specifically the proportion of patients starting highly active antiretroviral therapy (HAART) who achieve the outcome of virological suppression below 50 HIV-1 RNA copies/mL within 6 months. A prospective coh...

The British HIV Association (BHIVA) audit subcommittee aimed to survey UK clinic policy and practice regarding baseline assessment and immunization of newly diagnosed HIV-positive patients, and frequency of follow-up and testing in established patients in the UK. UK centres providing HIV care were requested to complete an online survey between Octo...

This review describes patterns of mortality among adults infected with HIV in the UK and assesses the contributions of late diagnosis of HIV infection and non-HIV-related disease to such mortality. In total, 387 adults with HIV who died between 1 October 2004 and 30 September 2005 after receiving care at 90 clinical centres in the UK were reviewed....

The aim of the study was to explore the factors surrounding modification of the first antiretroviral (ARV) regimen where drug switch occurred 3 months or more after initiation. Reference was made to the British HIV Association (BHIVA) guidelines on HIV management. A case note and questionnaire-based audit was carried out. Toxicity was the single mo...

The objective of this study is to evaluate the current management practices of patients with HIV and hepatitis B or C co-infection. A postal survey was made of 186 clinics in the UK between October 2003 and January 2004. In total, 100/186 (54%) clinics responded: 16% estimated their hepatitis B prevalence to be above 10%, 27% estimated their hepati...

Objective To assess adherence to the British HIV Association (BHIVA) 2001 guidelines for the management of HIV-infected pregnant women.MethodsA survey and a case note review were carried out using structured questionnaires sent to providers of adult HIV care in the UK and Ireland. Participants were women with HIV infection who delivered a live or s...

Objectives To assess the impact of and adherence to the British HIV Association (BHIVA) guidelines in routine clinical practice in the UK and Ireland.MethodsA self-completed postal survey of practice with regard to HIV management and maternity care of HIV-positive women was carried out. A case-note review of all patients starting their first antire...

We reviewed the impact of and assessed adherence to British HIV Association (BHIVA) guidelines in routine clinical practice. Feedback has been provided to clinical centres to facilitate any necessary change. We used a questionnaire to gauge clinicians' views on the guidelines and availability of antiretroviral therapy (ART) drugs and specialized te...

Full textFull text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (283K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References. 230 Selected References These references are in PubMed. This may not be the complete lis...

Editor-After all that has been written about AIDS, I am surprised that the BMJ should publish Bernard Rabinowitz's personal view.1 In portraying current ethical standards as the result of an unprincipled cave-in to some homosexual lobby Rabinowitz distorts both those standards and the history of public health medicine. For example, as early as the...

Treatment of the pentaruthenium salt [N(PPh3)2]2[Ru5C(CO)14] with an excess of [Rh(Cod)2][SbF6](cod = cycloocta-1,5-diene) yielded the monoanion [Ru5RhC(CO)14(cod)]– which has been isolated as its [N(PPh3)2]+ salt 1. Reaction of the monoanion with HBF4·Et2O gave the hydrido derivative [Ru5RhH(C)(CO)14(cod)]2. Compound 1 reacted with the gold salts...

The X-ray structure analysis shows that the octahedral hexanuclear mixed-metal cluster mu-carbido-mu-carbonyl-4:5 kappa(2)C-tridecacarbonyl-1 kappa(3)C,2 kappa(3)C,3 kappa(3)C,4 kappa(2)C,5 kappa(2)C-[6(eta(5))-pentamethylcyclopenyl]-octahedro-pentarutheniumrhodium(4 Rh-Ru)(8 Ru-Ru) [Ru5Rh(mu(6)-C)(CO)(13)(mu-CO)(eta(5)-C10H15)], encapsulating a C...

Treatment of the pentanuclear cluster [Ru4RhC(CO)12(η5-C5Me5)]1 with an excess of [NEt4][BH4] yielded the monoanion [Ru4RhC(CO)11H(η5-C5Me5)]– which has been isolated as its [NEt4]+ salt 2. Reaction of the monoanion with iodine solution gave the novel derivative [Ru4RhC(CO)11H(η5-C5Me5)I]3. Compound 3 crystallises in the monoclinic space group P21/...

Treatment of the hexanuclear cluster [Ru5RhC(CO)14(η5-C5Me5)]1 with 80 atmospheres of CO under 80 °C resulted in a series of decapping reactions yielding the complexes, [Ru3(CO)12], [Ru5C(CO)15] and a new green compound [Ru4RhC(CO)12(η5-C5Me5)]2. Cluster 2 crystallises in the monoclinic space group P21/n with a= 19.180(3), b= 13.940(3) and c= 10.72...

Das durch Birch-Reduktion aus 2,4-Dimethylanisol synthetisierte 1,4-Cyclohexadien (I) reagiert mit Fe-pentacarbonyl zu einem Gemisch der isomeren Komplexe (II) und (III).

The mixture of tricarbonyliron complexes produced from 1-methoxy-2,4-dimethylcyclohexa-1,4- diene was converted by CF3CO2H into a single product, tricarbonyl(1–5-η-2,4-dimethylcyclohexadienyl)iron hexafluorophosphate, without prior separation by chromatography. The corresponding 2-methoxy-3,5-dimethylcyclohexadienyl salt was the only complex obtain...

Iodine-132 was used as a tracer to demonstrate that ozone causes iodine vapor to be released from the sea surface. This rate of release was proportional to zone concentration in the range 0-100 ppb and depended on mixing of the water phase. At the mean ozone concentration existing at the sea surface the rate of iodine release was equivalent to an a...