Hilal Kaya Erdogan

• MD
• Professor (Assistant) at Eskişehir Osmangazi University

Background/Objective: Fibromyalgia syndrome (FMS) is a chronic, generalized pain condition characterized with widespread soft-tissue pain, fatigue, sleep disturbances, and tender points on physical examination. Although, there are numerous articles about the frequency of FMS in dermatologic diseases such as psoriasis and chronic urticaria, few stud...

Background and Design: Although acne vulgaris is generally regarded as a disease of adolescence period, it can occur in infancy, early childhood and prepubertal period. Acne may emerge as the first sign of pubertal maturation. In our study, we aimed to determine the acne prevalence in primary school children, then, evaluate the pubertal signs in th...

Background Seborrheic dermatitis (SD) is a chronic, inflammatory disease characterized by unknown etiopathogenesis. It affects skin areas rich in sebaceous glands. There are strong data on the relationship between nutrition habits, body mass index (BMI), psychoemotional status, and sebaceous gland diseases such as acne, rosacea, and androgenetic al...

Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma. This study was designed to measure psychological symptoms and health-related quality of life in patients with early-stage MF and compare the results with controls. Forty patients with early-stage MF and 40 age- and gender-matched healthy controls were included in the study...

Introduction Generalized granuloma annulare (GA) is an uncommon noninfectious granulomatous dermatitis. Phototherapy is often considered first-line therapy, with more evidence for psoralen ultraviolet A than narrowband ultraviolet B (NB-UVB). We aimed to evaluate the effectiveness and safety of NB-UVB in generalized GA and to review the literature....

Background Prurigo nodularis is a chronic pruritic dermatosis and narrowband-UVB (NB-UVB) phototherapy is considered an effective and safe treatment option in patients with multiple comorbidities. Objective In this study, the authors aimed to evaluate the efficacy and safety of NB-UVB phototherapy in the management of prurigo nodularis and to comp...

Background Oral isotretinoin is the most effective systemic treatment for acne patients who fail to respond to other forms of therapies. However, hesitations and concerns regarding its side effect profile may detain the patients from treatment. This study aimed to develop and validate the Isotretinoin Hesitancy Scale (IHS) among acne patients. Met...

Background Medical emergency complications may occur during dermatological, surgical, and cosmetic procedures. Aims This study aimed to investigate the frequency of dermatologists who experienced emergency complications as well as their level of knowledge regarding emergencies and basic life support. Methods The cross‐sectional descriptive study...

Background The efficacy and safety of secukinumab in psoriasis patients has been demonstrated in randomized controlled clinical trials. Objectives The authors aimed to evaluate the efficacy and safety of secukinumab in plaque psoriasis patients followed in our clinic. Methods Data from 101 plaque psoriasis patients who received at least 16 weeks...

Bullous pemphigoid is the most common bullous dermatosis seen in elderly population and accompanied by many comorbidities. Since immunoglobuline-E (Ig-E) antibodies play an important role in the pathogenesis of the disease, omalizumab targeting Ig-E proposes an effective and safe profile. In this study, we aimed to evaluate the efficacy and safety...

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening acute mucocutaneous disorders usually triggered by drugs. In this study, we aimed to evaluate the factors affecting mortality in patients with SJS-TEN. Our study is a retrospective cohort study, analyzing data collected from a total of 12 tertiary care centers...

Background Pyoderma Gangrenosum (PG) is a chronic disease characterized by recalcitrant skin ulcers. Objective We aimed to evaluate the demographic, clinical characteristics, treatments and factors affecting the treatment responses of patients with PG. Methods We performed a multicenter study of 12 tertiary care centers. We analyzed the data of t...

Dear Editor, Hirsutism is described as the presence of extreme terminal hair in androgen-sensitive areas of the female body and it affects 5%–15% of women worldwide.1 It is known that the frequency and severity of hirsutism can vary according to ethnicity and this can also be reflected in the modified Ferriman-Gallwey (mFG) visual scoring.2 Consid...

Local PUVA is one of the treatments used for resistant cases in palmoplantar dermatoses. In this study, we aimed to evaluate the efficacy and safety of local PUVA in the treatment of palmoplantar dermatoses. A total of 115 patients who were treated with local PUVA with the diagnosis of palmoplantar dermatosis (palmoplantar psoriasis, contact dermat...

Pyoderma gangrenosum (PG) is a chronic disease characterized by recalcitrant skin ulcers. We aimed to evaluate retrospectively the demographic, clinical characteristics, treatment data and factors affecting treatment responses of patients followed up with diagnosis of PG in 12 tertiary care centers from 8 different provinces in Turkey between the y...

Cutaneous Leishmaniasis (CL) is a disease caused by leishmania-type protozoans, which is transmitted by the bite of infected female phlebotomine sandflies and is characterized by ulcerated nodular lesions. Twenty-one pediatric cutaneous leishmania cases followed by pediatric infectious diseases and dermatology were included in the study. The demogr...

Introduction: Acne occurring in adults over the age of 25 years is known as acne tarda or adult acne. Three types of adult acne are recognized: persistent, late-onset, and recurrent acne. Most studies do not compare the characteristics between the three variants. In addition, little is known about adult acne in males. This study describes the epid...

Introduction: Pityriasis lichenoides (PL) is a papulosquamous disease affecting both children and adults, for which narrowband-UVB (NB-UVB) phototherapy is regarded as a commonly used treatment option. The aim of this study was to investigate the efficacy of NB-UVB phototherapy in the management of PL and to compare response rates in pediatric and...

Objective: Pemphigus vulgaris is a rare, mucocutaneous, autoimmune disease. In this case report, the diagnosis and follow-up process of a pemphigus vulgaris patient with multiple mucosal involvements will be explained. Case: Twenty-nine-year-old female patient was admitted to our clinic with complaints of widespread bleeding, burning and discomfort...

Background: Tattoos are very popular in today's world. Objectives: The aim of this study was to determine the demographics, the characteristics of tattoos, motivations for getting tattoos, tattooing practices and tattoo regret. Materials and method: This multi-centre, cross-sectional study was conducted among. 302 patients attending to the derma...

Livedo racemosa (LRac) refers to violaceous, red, or blue netlike mottling of the skin in an irregular pattern caused by circulatory abnormalities. Central venous catheters (CVC) are widely used in neonates who require intensive care to offer steady intravenous access. CVCs are covered with a hydrophilic polymer gel that reduces friction between th...

Background: Generalized pustular psoriasis (GPP) is a rare and severe inflammatory disease characterized by widespread and superficial sterile pustules on an erythematous background. Objectives: This multicentre study aimed to determine the clinical profile and course in a large cohort of patients with GPP. Methods: One hundred and fifty-six G...

Dünya Sağlık Örgütüne göre probiyotikler; uygun miktarlarda kullanıldığında, kullanıcının sağlığını olumlu yönde etkileyen mikroorganizmalardır. Prebiyotikler ise konağın sağlığı üzerinde etkili olan, cansız gıda komponentleri olarak tanımlamıştır. Prebiyotikler tek başına kullanılabileceği gibi, probiyotiklerle takviye şekilde de kullanıma uygundu...

Background: The differentiation between the pemphigoid diseases is essential for treatment and prognosis. In Turkey, data on the incidence of these diseases are insufficient. Our aim in this study is to determine the incidence, demographics and clinical characteristics associated with diseases of the pemphigoid group. Methods: We prospectively a...

Objectives: The purpose of our study was to compare healthy lifestyle behaviors between psoriasis patients and healthy controls. Methods: This case-control study included 80 psoriasis patients and 80 sex- and age- matched healthy controls aged over 18. Participants completed the socio-demographic data form and the Health-Promoting Lifestyle Profi...

Background The rate of cosmetic procedures and use of skincare products is considered to be affected during the pandemic period; however, this has not been investigated yet. Objective To determine whether the ongoing pandemic has changed people's habits related to skincare products and cosmetic procedures. Methods We conducted a multicenter surve...

Background Acne vulgaris (AV) may affect external appearance and significantly deteriorate the quality of life of patients. Therefore, patients make various inquiries about their disease and seek treatment options. Aims To investigate the social media usage habits of patients with AV concerning their diseases, and their recommendations for dermato...

Background and Design: Several randomized clinical trials demonstrated the safety and efficacy of secukinumab in the systemic treatment of moderate-severe psoriasis; however, real-life data is limited. Thus, this study aimed to assess the efficacy and safety of secukinumab in patients with psoriasis. Materials and Methods: In this study, 32 patient...

Background: Early-onset androgenetic alopecia (AGA) is the most common cause of alopecia in men under 30 years of age; however, its prevalence and non-genetic risk factors are not well documented. Our aim was to determine the early-onset AGA prevalence and to evaluate its relationship with lifestyle and dietary habits. Methods: This study was co...

Introduction: Onychophagia is defined as putting one's fingers into the mouth and biting the nails. We sought to evaluate the prevalence of onychophagia in university and high school students and its relation to sociodemographic factors, perceived stress, and quality of life. Methods: A total of 3,475 students were included in the study. A quest...

Objectives: This study aims to investigate the frequency of fibromyalgia syndrome (FMS) in rosacea patients and the relationship between disease disability score of FMS and quality of life score of rosacea. Patients and methods: This cross-sectional controlled clinical trial was performed between December 2017 and December 2018. One hundred fema...

The pathogenesis of chronic spontaneous urticaria (CSU) is incompletely understood. There is a growing interest in the role of the coagulation cascade in chronic urticaria. Rotational thromboelastometry (ROTEM) assay enables the global assessment of coagulation status. In the present study, we aimed to test the coagulation profile in children with...

Background Hair graying is a natural process in aging and is not usually associated with a medical problem. It sometimes may occur at early age and is called premature hair graying (PHG). Pathogenesis of PHG is not clear but it was associated with various systemic diseases such as coronary artery diseases, osteopenia, and hypothyroidism. Objective...

We read Cosansu’s commentary entitled ‘’ Effectiveness of the new inflammatory parameters in patients with chronic spontaneous urticaria’’ to our study with great interest. The author remarked that a limited number patients had C-reactive Protein levels and it was not specified whether there were any other drugs used by the patients and no informat...

Background and Design: Thyroid diseases often cause various findings in hair, skin and nails. Some of them may be regressed by the treatment of thyroid disease. We aimed to evaluate the cutaneous manifestations in patients with thyroid disease under treatment. Materials and Methods: This cross-sectional study included 97 consecutive patients with t...

Background: The efficacy and safety of ustekinumab have been demonstrated in randomized clinical trials; however, there are few real-life data evaluating ustekinumab. Objectives: This observational, retrospective follow-up study included 33 patients with moderate to severe psoriasis vulgaris. Patients were >18 years old and received at least 16...

Background and Design: Clinical variants, subtypes, and early mycosis fungoides (MF) lesions may mimic other dermatoses. MF is the most common type of cutaneous T-cell lymphomas. In our study, we aimed to evaluate the clinical and histopathological features of patients with classical and variants, subtypes, or atypical forms of MF in our dermatolog...

Background: Anxiety sensitivity (AS) is a continuous fundamental fear and defined as extreme fear of anxiety sensations and symptoms. High AS can cause tendency to anxiety disorders. There are many studies evaluating the anxiety in patients with acne; however, AS has not been investigated. Objective: We aimed to investigate AS in patients with a...

Background/Objectives: Psoriasis is an inflammatory skin disease characterized by erythematous squamous plaques. It has negative physical, psychological, and social effects. Psychiatric comorbidities such as anxiety and depression can accompany to psoriasis. In our study, we aimed to evaluate the anxiety sensitivity (AS) in psoriasis patients. Meth...

Background and Design: We aimed to evaluate whether alopecia areata (AA) patients had hearing loss with pure-tone audiometry. Materials and Methods: In the study, 48 patients with AA and 39 healthy volunteers were included. All the patients were examined by the otorhinolaryngologist and audiometric examinations were performed using a pure-tone audi...

Melanom dışı deri kanserleri beyaz ırkta en sık görülen kanserlerdir ve bunlar arasında en sık bazal hücreli karsinom (BHK) görülür. BHK yavaş ilerleyen, lokal agresif ve nadiren metastaz yapan bir deri kanseridir. Mortalitesi düşük olmasına rağmen morbiditesi ve hastalık maliyet yükü yüksektir. Kutanöz skuamöz hücreli karsinom (SHK) ise ikinci en...

The purpose of this study was to compare distress tolerance in patients with psoriasis and patients with non-psychodermatological diseases and healthy controls. Parameters including sociodemographic data such as age, gender, cigarette and alcohol habits were studied, and the Distress Tolerance Scale (DTS) and Beck Anxiety Scale (BAS) were used for...

Aim Premature hair graying (PHG) is commonly observed in society, but there are a few studies evaluating risk factors associated with PHG. We aimed to evaluate the socio‐clinical risk factors associated with PHG in this study. Methods A total of 1192 volunteers between 18 and 20 years old were included in this cross‐sectional study. Volunteers wer...

Objective: T regulatory (Treg) cells play a role in autoimmunity and vitamin D is one of the factors involved in regulation of Treg cells. In this study, it is aimed to evaluate the relationship between Treg cells and disease-related parameters and serum vitamin D levels in chronic spontaneous urticaria (CSU) patients. Methods: The percentage of Tr...

Background and Design: Herpes zoster (HZ) occurs by reactivation of the latent varicella zoster virus at dorsal root ganglia. In the literature, there are studies on socio-demographic and clinical characteristics of patients with HZ in our country and in the world, however, there has been no study performed in our region. We aimed to evaluate demog...

Introduction: This study used real-world data to evaluate the effectiveness and reliability of omalizumab in treating recalcitrant chronic spontaneous urticaria in Turkish patients. Methods: Study data were collected retrospectively from eight tertiary-care hospitals in Turkey. This study included 132 patients with chronic spontaneous urticaria...

Background: Irisin, a hormone like myokine, is identified to the relation with insulin resistance and metabolic syndrome recently. In the literature to date, there are no studies evaluating serum irisin levels in psoriasis patients. We aimed to elucidate the pathogenesis of insulin resistance in psoriasis patients by evaluating serum irisin levels...

In this study, we aimed to investigate the bone mineral density (BMD) of psoriasis patients, compare with healthy control group, and to evaluate whether topical corticosteroids and systemic treatments affect BMD in psoriasis patients. Forty psoriasis patients admitted to dermatology outpatient clinic and 36 healthy subjects were included in the stu...

Purpose: The mechanism of action of omalizumab in chronic spontaneous urticaria (CSU) is not exactly known. In previous studies, D-dimer which is a fibrin-degradation product and interleukin-31 which has a role in inflammation were found to be decreased in patients with chronic urticaria (CU) treated with omalizumab. However, to our knowledge, ther...

Background Rosacea is a common dermatosis characterized by erythema, telangiectasia, papules and pustules. Objective We aimed to evaluate contact sensitivity in the rosacea patients. Methods We included 65 rosacea patients and 60 healthy volunteers in the study. The patient and control groups were patch tested with European baseline series and co...

Introduction Rosacea is a chronic, inflammatory dermatosis which develops due to the effect of genetic and environmental factors. Aim To evaluate the oxidative stress in rosacea patients by measuring serum total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) and advanced oxidation protein products (AOPP) levels...

Scabies is a common, extremely pruritic and contagious mite infestation caused by Sarcoptes scabiei var. hominis. Scabies in infants has a different clinical appearance from adults with the presence of more vesicles, pustules, and crusts; involvement of palms, soles, fingers, facial and scalp more frequently, and more inflammatory lesions. The diag...

Background While phototherapy is a well-established treatment for many dermatoses, data from the literature regarding its use in elderly patients are quite limited. Objective In this study, we aimed to determine the phototherapy indications in geriatric patients and to evaluate the effectiveness and reliability of phototherapy in this group. Meth...

ABSTRACT Aim: The glutathione-S-transferases (GSTs) refers to a group of detoxification enzymes that are pivotal components of the cellular defense against oxidative stress and the expressions of GST isoforms have been shown in human skin. This study was planned to determine the effects of GST polymorphisms on the molecular etiology of the lichen p...

Objective: Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous disease characterized by annular plaques. In this study, we aimed to describe the clinical and pathological features of the patients diagnosed with AEGCG. Methods: The demographic, clinical and pathological features of patients who diagnosed with AEGCG were recorde...

Porokeratosis mibelli (PM) is a rare, chronic keratinization disorder that has unknown etiology and may be inherited. PM is considered a premalign lesion, characterized by thin plaques with atrophic center and surrounded by a hyperkeratotic border. PM is more common in men and is usually located in the extremities, but occasionally the involvement...

Objective: We aimed to evaluate the role of neurotrophins in relation to metabolic syndrome (MetS) and psoriasis by determining brain derived neurotrophic hormon (BDNF), nerve growth factor (NGF), tumor necrosis factor-α (TNF) and interleukin-6 (IL) levels in serum and skin samples of psoriasis patients and healthy controls. Methods: The BDNF, NGF...

Giriş: Psoriasis eritemli skuamlı plaklar ile karakterize kronik, inflamatuar bir deri hastalığıdın Psoriasis hastalannda anksiyete, depresyon, cinsel bozukluklar, uyku bozukluklan ve madde bağımlılığı gibi bir çok psikiyatrik komorbiditenin daha sık olduğu bildirilmiştir. Amaç: Biz de çalışmamızda psoriasis hastalarında anksiyete duyarlılığını değ...

Giriş: Akne pilosebase ünitenin kronik inflamatuvar bir hastalığıdır. Toplumda oldukça yaygın görülen akne aktif evrede sıklıkla eritemli papülopüstüler lezyonlara neden olur, bu lezyonlar skar ve pigmentasyon bırakarak geriler. Hastalarda dış görünüş ile ilgili memnuniyetsizlik, utanç, öz beğeni eksikliği, yaşıtlar ve karşı cins ile sosyal iletişi...

Kaposi's sarcoma (KS) is a multifocal and angioproliferative neoplasm. KS may be accompanied by psoriasis; however, in most of these cases the main mechanism involves iatrogenic KS associated with the immunosuppressive drugs that are used in psoriasis treatment. In angioproliferative lesions as a result of venous insufficiency and stasis dermatitis...

Objective: To evaluate the relationship between the serum resistin levels and metabolic syndrome (MetS) in chronic spontaneous urticaria (CSU) patients. Methods: In the study 42 CSU patients and 42 healthy volunteers were included. Height, weight, waist circumference, and blood pressure measurements were assesed for both of the groups. Fasting bloo...

Nevus comedonicus is a rare hamartoma of pilosebaceous unit. Lesions are found the most common in face and neck, body, upper arm, respectively, and localized, linear numerous groups of comedones. Sometimes, after lesion inflammation fistulas, sinuses and severe scars can often seen. Nevus comedonicus has been described in association with various s...

Prurigo pigmentosa is a rare skin disease of unknown etiology. Prurigo pigmentosa is seen frequently in young Japanese women. It is characterized by pruritic, erythematous macular, papular, papulovesicular lesions and reticular pigmentation. Lesions often localize back, neck, and chest. Dapsone and minocycline are most commonly used in the treatmen...

Attention deficit hyperactivity disorder (ADHD) is characterized by attention, concentration, mobility, and impulse control problems and is among the most frequently seen psychiatric disorders during childhood. Our aim was to evaluate cutaneous findings in children and adolescents with ADHD. In our study we found that onychophagy, traumatic skin ch...

Background: Androgenetic alopecia (AGA) is the most common cause of alopecia in men. In the literature, although there are in vitro studies investigating the relationship between oxidative stress and AGA, any in vivo study does not exist. Aim: Our aim was to evaluate the oxidative stress status in male patients with early-onset AGA by measuring...

Background Acne vulgaris (AV) is a chronic, inflammatory skin disease that may cause various psychiatric and/or psychological problems. Objective In this study, we aimed to determine the effect of AV on the quality of life in the Turkish population using the Turkish Acne Quality of Life Index (TAQLI). Methods A total of 960 patients with AV who a...

Öz Özet: Psoriazis eritemli, skuamlı ve endure plaklarla karakterize, en sık saçlı deri ve ekstansör yüzeyleri tutan kronik bir dermatozdur. Metotreksat psoriazis tedavisinde yaygın kullanılan sentetik bir folik asit analoğudur. Kanda nadiren toksik düzeylere ulaşarak şiddetli yan etkilere sebep olur. Bu durumda akut dönemde psoriatik plaklarda ül...

ZET: Miyazis, Diphtera takımı sinek larvalarının oluşturduğu parazitik infestasyondur. Tropikal ve subtropikal bölgelerde sık görülmekle birlikte, ülkemizden de bildirilen vakalar bulunmaktadır. Burada 81 yaşında erkek hastada, uzun süreli ve ihmal edilmiş bazal hücreli karsinom üzerinde gelişen miyazis olgusu sunulmaktadır. ANAHTAR KELİMELER: Baza...

Pilomatricoma (PM; calcifying epithelioma of Malherbe) is a benign tumor originating from the matrix of the hair follicles. Clinical types of the tumor are familial, perforating, multinodular, exophytic, anetodermic, and giant PM. The bullous type is seen only in 3 to 6% of cases. Because the bullous areas detected in PM are filled with lymphatic l...

Febrile Ulceronecrotic Mucha-Habermann disease is a rare and potentially fatal variant of pityriasis lichenoides et varioliformis acuta and is characterized by high fever, constitutional symptoms, and acute oncet of ulceronecrotic lesions. We present an 11-year-old male with Febrile Ulceronecrotic Mucha-Habermann disease who was cured with methotre...

Fox-Fordyce Disease (FFD) is a rare, chronic, pruritic, inflammatory disorder of apocrine glands. It is characterized by dome-shaped, firm, discrete, skin-colored, and monomorphic perifollicular papules. The most common sites of involvement are axillae and anogenital and periareolar regions which are rich in apocrine sweat glands. Treatment is diff...

Cutaneous leiomyomas are rare benign tumors arising from smooth muscle cells. The combination of cutaneous leiomyomatosis, uterine leiomyomatosis and renal cell cancer is referred to as ''multiple cutaneous and Uterine Leiomyomatosis syndrome (Reed's syndrome)''. A forty-five-year-old female patient was admitted to our clinic with multiple painful...

ZET: Psoriasisde kalıcı deri inflamasyonu endotelyal disfonksiyonu ve sonrasında gelişen ateroskleroz ile kardiyovasküler hastalıkların başlangıcını oluşturmaktadır. Subklinik aterosklerozun değerlendirilmesinde karotid arter intima media kalınlığının (kİMK) ultrasonografi ile değerlendirilmesi önem taşımaktadır. Biz de çalışmamızda psoriasis hasta...

Background and Design: The definition of emergent diseases includes potentially risky diseases that need urgent medical intervention. Diagnostic and therapeutic processes are managed mostly at ourpatient setting in dermatology. Therefore, it is unclear that which diseases are real emergencies and which patients apply urgently. There are a few studi...

The neonatal period is regarded as the first 4 weeks of extrauterine life. In the literature, there are numerous articles about the skin findings in neonates and the results of these studies show differences according to races and environmental factors. Our objective was to evaluate the skin lesions seen in neonates delivered in our hospital and to...

Observations: We report a 75-year-old woman with bullous morphea characterized by disseminated erythemato-pigmentous plaques and a few blisters on some morphea plaques at the beginning of first visit. While she was under narrow band UV therapy, she discontinued the treatment and refused to have any more after 13 sessions. One month later, she reapp...