Hikmet Yilmaz

Hikmet Yilmaz
Manisa Celal Bayar University · Department of Neurology

Professor

About

51
Publications
18,801
Reads
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495
Citations
Citations since 2016
17 Research Items
318 Citations
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060

Publications

Publications (51)
Article
Introduction Narcolepsy type 1 (NT1) is caused by hypocretin deficiency, the pathophysiology of narcolepsy type 2 (NT2) has not been delineated. Except for the hypocretin deficiency and cataplexy, all clinical and laboratory features used in the diagnosis of NT2 are identical to those used for NT1. The aim of this study was to assess the rapid eye...
Article
Introduction Many patients with stroke also have sleep breathing disorders (SBD), most of which is obstructive sleep apnea (OSA). Methods Sixty patients with a history of stroke aged under 55 years were included in our study. The demographic characteristics (age at stroke, sex, body mass index) of the patients and etiology of stroke was evaluated...
Article
Aims: Both obesity and sleep disorders represent an important public health problem. In this study, the prevalence and consequences of obesity and associated sleep disorders were investigated in the Turkish adult population. Methodology: Data were analyzed in 5019 subjects who had available body mass index (BMI) data from a population-based study i...
Article
Full-text available
IntroductionHypoxia during sleep in obstructive sleep apnea syndrome (OSAS) increases intracranial pressure, decreases cerebral perfusion pressure, and alters vascular supply to the optic nerve. Pattern visual evoked potential (pVEP) has revealed that it causes alterations in the optic nerve, and optic coherence tomography has shown that it causes...
Article
Aim: The present study aimed to investigate and compare possible changes in amplitude and latency of pattern visual evoked potentials (PVEP) and thickness of quadrants of the macula (TQM) using optic coherence tomography (OCT). Materials and methods: According to polysomnography examinations, 30 mild, 30 severe, 30 controls were included in the...
Article
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PurposeTo investigate the possible changes in retinal nerve fiber layer (RNFL) by optic coherence tomography and in the amplitudes and peak times (PTs) in pattern visual evoked potential (pVEP) and to compare them in obstructive sleep apnea syndrome (OSAS).Methods This prospective study included patients with mild OSAS (n = 30), severe OSAS (n = 30...
Article
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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary microangiopathy with adult onset caused by a missense mutation in the NOTCH3 gene in chromosome 19p13. It presents with autosomal dominant arteriopathy, subcortical infarctions, and leukoencephalopathy. Its common clinical presentati...
Article
Abstract: Sleep problems may have negative effects on work–life balance, overall health, and safety. We aimed to investigate the association between sleep disorders and absenteeism and delay to work (being late or tardy) among the working adult population. The study was conducted by using data from a large survey of working adults who participated...
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Objective: In this study, it was aimed to compare the sleep quality of healthy children with the actigraphic evaluation and quality of life of monosymptomatic enuresis children of similar age groups. Materials and Methods: This prospective study was conducted in Celal Bayar University Faculty of Medicine and has been submitted to the Department of...
Article
Restless legs syndrome (RLS) is a disease characterized by some type of dysesthesia, an indescribable abnormal sensation in the extremities. Our objective was to determine whether the visual evoked potentials (VEP) can be used as a quantitative monitoring method to evaluate demyelination-remyelination and neurodegeneration in the patients with RLS....
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Myasthenia gravis is a disease of neuromuscular junction due to auto-immune destruction of the acetylcholine receptors. Behçet's disease, on the other hand, is a multisystemic vascular-inflammatory disease. Both conditions are not common in the general population although their association has not been reported in the literature. We wanted to prese...
Article
Introduction: Obstructive sleep apnea syndrome (OSAS) is an independent risk factor for development of atherosclerotic processes because it leads to hypertension, impaired glucose metabolism, obesity and metabolic syndrome, cardiac diseases, elevated blood pressure, and increased level of cholesterol, triglycerides, homocysteine, and coagulation. M...
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Background: Idiopathic generalized epilepsy (IGE) is an epilepsy form without an underlying brain lesion or neurological indication or symptom. Recent investigations on the genetic origins of IGE and its subtypes report that certain mutations of various ion and non-ion channels genes in the central nervous system may be associated with IGE. Purpo...
Conference Paper
Full-text available
SESSION TITLE: Sleep Disorders Posters I: Diagnosis SESSION TYPE: Original Investigation Poster PRESENTED ON: Wednesday, October 28, 2015 at 01:30 PM-02:30 PM PURPOSE: Sleep problems may have deleterious effects on work-life balance, overall health and safety. We aimed to investigate sleep related absenteeism and delay to work among the working adu...
Article
Percheron artery syndrome is characterized by infarction at the paramedian nucleus of the thalamus and mesencephalon. Its classical triad comprises altered mental status with various clinical findings ranging from confusion to coma, restricted vertical gaze, and impaired memory. In this study, three cases of occlusion of the Percheron’s artery were...
Article
Sleep disorders constitute an important public health problem. Prevalence of sleep disorders in Turkish adult population was investigated in a nationwide representative sample of 5021 Turkish adults (2598 women and 2423 men, response rate: 91%) by an interviewer-administered questionnaire. Insomnia was defined by the DSM-IV criteria, habitual snori...
Article
AimThe prevalence of insomnia is influenced by environmental factors. This study aimed to investigate the prevalence of insomnia and its sociodemographic and clinical correlates in a general population-based survey in Turkey.Methods This population-based study included 4758 subjects among 5021, who participated in TAPES (Turkish Adult Population Ep...
Article
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The association of obesity with sexual dysfunctions is complex and far from clear. Most former studies consisted of small samples and did not control several possible confounding factors. Our aim was to investigate the association of BMI with current sexual dysfunction in males and females in a nationally representative population sample after cont...
Article
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Background: The HLA-DQB1*06:02 allele across all ethnic groups and the rs5770917 variation between CPT1B and CHKB genes in Japanese and Koreans are common genetic susceptibility factors for narcolepsy. This comprehensive genetic study sought to assess variations in CHKB and CPT1B susceptibility genes and HLA-DQB1*06:02 allele status in Turkish pat...
Article
Sleep disordered breathing (SDB) represents a major public health problem. We investigated the risk of SDB and associated factors in the Turkish adult population. We collected data by an interviewer‐administered questionnaire in a nationwide representative sample of 5021 adults (2598 women, 2423 men) with a mean age of 40.7 years (SD:15.1) in 2010....
Article
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Respiratory failure is a significant cause of morbidity and mortality in neuromuscular diseases. Although clinical findings and respiratory function tests aid in diagnosing sleep-related breathing disorders, polysomnography is the gold standard for the diagnosis of these disorders. We aimed to investigate the role of sleep-wake symptoms and clinica...
Article
The aim of the study was to investigate sleep disturbances of cardiac surgery patients with or without elevated S100B levels. Twenty-two patients with serum S100B > 0.3 microg/l (study group) 12 hours after cardiac surgery with cardiopulmonary bypass and 23 patients with serum S100B < 0.3 (control group) were investigated in a prospective study. Th...
Article
Children with allergic rhinitis (AR) are reported to have disturbed sleep and daytime fatigue due to nasal obstruction. To evaluate sleep impairment in children with AR using actigraphic evaluation. Fourteen children aged 7 to 16 years with grass pollen-sensitized seasonal AR were enrolled. They completed the Total 4-Symptom Score (T4SS) scoring sy...
Article
Pregnancy is a period when the estrogen/progesterone ratio rises considerably because of the passage of estrogen from the placenta. These changes in the level of estrogen during pregnancy increase the sensitivity of the central nervous system to cathecholamines. As a result, the sensitivity of the receptors in both the visual cortex and the inner p...
Article
In patients with clinical findings of cerebrovascular accident, computed tomography is initially necessary for the differential diagnosis of mass lesions such as malignancy. If the lesion cannot be demonstrated with computed tomography or if there is a suspicion, magnetic resonance imaging should be performed. The diagnosis of a stage IV squamous c...
Article
Purpose: OSAS is a disease which involves a wide range of symptoms from simple snoring extending up to the tables accompanied by serious cardiovascular, pulmonary, endocrine and psychiatric diseases. In our study; we aimed to look into the variety of the psychiatric diseases observed in patients with diagnosis of OSAS and to discuss the spectrum of...
Article
Catathrenia is a rare, idiopathic, sleep-related respiratory condition characterized by irregular groans, which occur during prolonged expiration in sleep. The origins of catathrenia remain inexplicable, the long-term prognosis unexplained. Moreover, empirical treatment with neither pharmacological nor non-pharmacological approaches was satisfactor...
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There is not a wide agreement upon rate of conversion disorder within Turkish population. The aim of this study was to determine the prevalence of conversion disorder with pseudoneurological symptoms or deficits and related risk factors in a city. In total, 1,086 people, aged 15-65 years old, were selected from the city of Manisa, Turkey to take pa...
Article
The purpose of this study was to investigate the changes in sleep characteristics in patients who underwent coronary artery bypass grafting (CABG) surgery, using both subjective and objective tests in the early (preoperative) and late (postoperative) periods. Forty-five patients who underwent CABG and did not previously have any sleep disturbance w...
Article
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Levetiracetam-treated patients commonly report daytime drowsiness, fatique, asthenia and decreasing of motor activity. However the origin of these reported side effects are still debated, we aimed to clarify effect of levetiracetam on sleep. Therefore this prospective study was conducted to evaluate the effects of levetiracetam on motor activity, a...
Article
The purpose of this study was to investigate changes in sleep characteristics by examining both subjective tests and objective parameters such as actigraphic sleep analysis in patients who underwent coronary artery bypass graft surgery (CABG). Forty-five patients who underwent CABG operations and did not have any sleep disturbance were examined. Th...
Article
Cognitive brain dysfunction after open heart surgery is a serious complication caused by cardiopulmonary bypass (CPB). The presence of gaseous and/or particulate emboli in the CPB circuit and cerebral hypoperfusion may be the causes of neurologic problems after cardiac operations. In this prospective study we examined 42 consecutive cardiac surgery...
Article
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This study aimed to investigate the toxic effects of paclitaxel on sensory and motor nerve conduction velocities (SNCV and MNCV) and motor unite action potentials (MUAP) in adult male Spraque-Dawley rats. Rats were divided into two equal groups as the control and paclitaxel group. Control animals were injected with 0.5 ml normal saline, while those...
Article
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Parkinson's disease (PD) is clinically characterized by a resting tremor, bradykinesia, cogwheel phenomenon, rigidity, disorder of postural reflexes and especially changes in voice and speech. We studied 30 PD patients who were treated with dopamine and 20 normal subjects as the control group. The parameters of vocal fold edges, glottal closure, ve...
Article
As a result of a regression in the ovarian functions, oestrogen level in circulation during the menopause drops to 1/50 of its value in the normal reproductive cycle. Excitatory oestrogen increases the sensitivity of the central nervous system to catecholamines by changing the opening frequency of voltage-related L-type calcium channels and augment...
Article
Hormonal changes that occur during the menstrual cycle of women influence the visual function of females. Estrogen is reported to cause a decrease in the visual transmission time by increasing the sensitivity of receptors in the optic pathways to dopamine. The aim of this study was to search if pattern reversal evoked potentials (PRVEPs) changed du...
Article
Full-text available
ÖZET Amaç: Obstrüktif Uyku Apne Sendromu (OSAS) basit horlamadan ciddi hastal›klar›n (pulmoner, kardiyovasküler, psikiyatrik vb) birlikte görüldü¤ü tablolara kadar uzanan genifl semptomlar dizi- sini kapsar. Çal›flmam›zdaki amac›m›z elde ettiimiz ham verilerden yola ç›karak, OSAS tan›s› konan hastalar- da gözlenen psikiyatrik hastal›klar›n çeflitli...
Article
Full-text available
Epilepsi klinik yelpazesi geniş heterojen bir hastalıktır. Yelpazenin en solunda uygun tedavi ile nöbetsiz yada seyrek nöbet geçiren olgular yer alırken; yelpazenin en sağında ilaç tedavisine rağmen nöbetleri ısrar eden, motor-mental retardasyonun eşlik ettiği, sık nöbetlerin ve kadastrofik epilepsi tablolarının eşlik ettiği olgular bulunmaktadır....

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