Hidemi Takimoto

Hidemi Takimoto
National Institute of Health and Nutrition · Department of Nutritional Epidemiology

Doctor of Medicine

About

130
Publications
29,518
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
1,717
Citations
Additional affiliations
April 2012 - present
National Institute of Health and Nutrition
Description
  • Interventions to improve maternal nutritional status in underweight pregnant women
January 2007 - December 2008
The University of Tokyo
April 2005 - March 2012
National Institute of Public Health
Position
  • Senior Researcher

Publications

Publications (130)
Article
Eating frequency has been associated with nutrient intake and diet quality. The aim of this study was to examine the association between daily nutrient and food group intake and consumption of breakfast and/or snacks among young Japanese adults, as secondary analysis of the 2012 National Health and Nutrition Survey in Japan involving 1,420 men and...
Article
Little is known about the optimal daily magnesium (Mg) intake for individuals with high levels of physical activity. The aim of this study was to clarify the optimal dietary Mg intake for people with high levels of physical activity in a scoping review. In this review, we searched MEDLINE and Japan Medical Abstracts Society for studies published up...
Article
Previous systematic reviews, which focused on sugars intake and its relationship with health issues were mainly conducted in Western countries, not Asian countries characterised by differences in dietary habits and disease prevalence. The scarcity of Asian studies may be attributed to the lack of assessment tools for estimating sugars intake. To pr...
Article
Full-text available
Identifying trends in dietary salt sources is essential for effectively reducing salt/sodium intake. This study aimed to examine the trends in dietary salt sources among Japanese adults using the 2007–2019 National Health and Nutrition Survey data collected from 95,581 adults aged ≥20 years. Dietary intake was estimated using the 1-day household-ba...
Article
Full-text available
Objectives Minor health complaints related to stress, mental health, sleep, and fatigue are closely associated with each other, and their deterioration may cause lifestyle diseases. The health status of people can be predicted through a questionnaire by exploring the relationship between their state of minor health complaints and objective health s...
Article
Full-text available
Objectives The later achievement of gross motor milestones during infancy is associated with adiposity in early childhood. However, the associations between gross motor development and adiposity after entering primary school are unclear. This study examined the associations between the ages at which six gross motor milestones were achieved and adip...
Poster
Full-text available
Several systematic reviews have focused on sugar intake and its relationship with health issues in mainly Western countries, not Asian counterparts with different dietary habits and disease structures. This scoping review aimed to show the overview of epidemiological studies of sugar intake in Asian countries, primarily focusing on the dietary asse...
Poster
Full-text available
Free sugars intake may be related to adverse cardiometabolic outcomes, including weight gain and blood pressure and lipid profile. However, the majority of studies have conducted in Western countries and investigated the effects of free sugars from soft drinks. This cross-sectional study aimed to investigate this association in Japanese adults with...
Article
Objective The association between adult-attained height and risk of colorectal cancer remains elusive among the Japanese population. We performed a systematic review and meta-analysis of epidemiological studies in Japan. Methods We systematically searched the MEDLINE (PubMed) and Ichushi databases and complemented it with manual search to identify...
Article
Objective Placenta-derived extracellular vesicles and their cargoes, especially microRNAs (EV-miRNAs), may contribute to fetal and placental development. During pregnancy, the levels of several maternal blood EV-miRNAs, including miRNAs of placental origin, vary among individuals and change throughout gestation. However, the effects of these miRNAs...
Article
Full-text available
Background Low birth weight (LBW) and fetal growth restriction are associated with the development of cardio-metabolic diseases later in life. A recent Mendelian randomization study concluded that the susceptibility of LBW infants to develop hypertension during adulthood is due to the inheritance of hypertension genes from the mother and not to an...
Article
Full-text available
We aimed to examine the relationships of lifestyle habits and nutritional status with emotional behavior among schoolchildren in Sri Lanka. Five hundred and eight schoolchildren (195 boys and 313 girls) aged 5–10 years were included. Emotional and behavioral problems were assessed using the Strengths and Difficulties Questionnaire. Nutritional stat...
Article
Background Increasing trend of diabetes is significant public health threats. This is a consecutive cross-sectional study aimed to estimate the attribution of overweight for diabetes prevalence in Japan. Methods We used individual data aged 20 years and older of National Health and Nutrition Survey in 1997 (2349 men and 3588 women), 2002 (2075 and...
Article
Full-text available
Background Obese pregnant women are known to experience poorer pregnancy outcomes and are at higher risk of postnatal arteriosclerosis. Hence, weight control during and after pregnancy is important for reducing these risks. The objective of our planned randomized controlled trial is to evaluate whether the rate of change in body weight in obese wom...
Article
Full-text available
The maternal diet can potentially influence the life-course health of the child. A poor-quality maternal diet creates nutrient deficiencies and affects immune–metabolic regulation during pregnancy. The nutrient-based overall dietary quality can be assessed using the Nutrient-Rich Food Index 9.3 (NRF9.3), which measures adherence to the national ref...
Article
Objectives The purpose of this study was to examine the prevalence of frailty and its associated factors in community-dwelling middle-aged and elderly adults in Settsu and Hannan cities, which are located in the north and south of Osaka prefecture, respectively.Methods We conducted a mailed, self-administered, questionnaire survey of individuals ag...
Article
Full-text available
Dish-based nutrient profile analyses are essential for setting goals to achieve a balanced diet. In 2014, the Japanese government proposed the “Healthy Meal” criteria, which requires a salt content of 3 g/650 kcal per meal. To examine the current intake status of a nationally representative sample, we conducted a series of secondary analyses of the...
Article
Objectives The Japanese diet pattern is closely associated with seasonal supply, but there are limited studies on how seasonal changes affect dietary intake in Japan. Hokkaido, located in the northernmost tip of Japan, is a region with abundant dairy and agricultural produce. The diet in Hokkaido may be sensitive to the seasonal supply. This study...
Article
Objectives Dish based nutrient profile analyses are essential in setting goals to achieve a balanced diet. The Japanese enjoy longevity, but their current diet is still high in salt, which was 10.1g/day among adults in the 2019 National Health and Nutrition Survey. In 2013, the Japanese government's “Health Meal” proposed the salt content of 3g/650...
Article
Full-text available
Background/objectives Although higher diet quality is related to higher socioeconomic status among adults, it is unclear whether this result could be generalized to children. Elementary and junior high school lunch programs may contribute to the reduction of socioeconomic disparities in diet quality. We examined the association between diet quality...
Article
Objective: Nutrient profile (NP) models, which classify or rank foods according to their nutritional composition, are commonly used as a nutrition policy in countries outside of Japan to evaluate the nutritional quality of foods. This study investigated the characteristics of NP models in other countries to determine the challenges that should be c...
Article
Full-text available
Background Previous epidemiological studies have demonstrated the prevalence and relationship of various factors associated with sarcopenia in older adults; however, few have examined the status of sarcopenia in middle-aged adults. In this study, we aimed to, 1) evaluate the validity of the finger-circle test, which is potentially a useful screenin...
Article
Full-text available
Background Consumption of home-prepared meals may lead to better nutritional intake. Few studies have examined the association between the frequency of consuming meals prepared away from home and the inadequacy of nutritional intake based on nutritional standards and food group intake. We therefore aimed to investigate this issue among Japanese adu...
Preprint
Full-text available
Low birth weight is associated with the development of cardio-metabolic diseases later in life1-4. A recent Mendelian Randomization Study concluded that the susceptibility of low-birth-weight infants to develop hypertension during adulthood is due to the inheritance of hypertension genes from the mother, and not to an unfavorable intrauterine envir...
Article
DNA polymerase ζ (pol ζ) is involved in translesion replication (translesion synthesis, TLS) and plays an essential role in embryogenesis. In adults, pol ζ triggers mutation as a result of error-prone TLS and causes carcinogenesis. The catalytic subunit of pol ζ, REV3, is evolutionarily conserved from yeast and plants to higher eukaryotes. However,...
Article
Objective: This study aimed to compare dietary reference intakes (DRIs) and their applications in Japan and other countries to facilitate future development of DRIs for Japanese. Methods: Information on DRIs in Japan, the United States/Canada, the United Kingdom, Australia/New Zealand, and the European Union was collected mainly through webpages of...
Article
In Japan, mean birth weight has decreased and prevalence of low birth weight babies is higher than other OECD countries. We examined the relationship of maternal weight gain with dietary intake and smoking during pregnancy. Women with singleton pregnancies without any complications who had prenatal medical check ups at a hospital in Tokyo from July...
Preprint
Full-text available
Background: Prior epidemiological studies have demonstrated the prevalence and the relationship of various factors associated with sarcopenia in older adults; however, few have examined sarcopenia status in middle-aged adults. In the present study, we aimed: 1) to evaluate the validity of the finger-circle test, which is potentially a useful screen...
Article
Full-text available
PurposeThe association between free sugars and nutrient intake is unclear in Japanese adults with relatively low free sugars intake. This cross-sectional study aimed to elucidate this relationship using data from the 2016 National Health and Nutrition Survey, Japan, and according to the current World Health Organization (WHO) guidelines for the pre...
Article
Full-text available
Objective: This study aimed to describe prevalence and trends in Japan in nutritional indicators/nutritional status, according to the Global Nutrition Monitoring Framework on Maternal, Infant and Young Child Nutrition (WHO, 2014). Methods: We used vital statistics data on birth weight since 1951. Height and weight data for children, adolescents, an...
Article
Objective: There are regional health disparities in Japan regarding the physical condition and lifestyle as demonstrated in the gaps among prefectures. However, no regional annual trends have been reported. This study investigated the regional trends in dietary intake among Japanese adults. Methods: Overall, 140,817 Japanese participants (64,773 me...
Article
Objective: This paper describes the key laws, policies, and activities related to Shokuiku (food and nutrition education). Methods: The Basic Law on Shokuiku, the Basic Program for Shokuiku Promotion, and Shokuiku promotion programs by prefectural and municipal governments were summarized. Results: The Basic Law on Shokuiku (enacted in 2005) aimed...
Article
Objectives: The National Health and Nutrition Survey (NHNS; formerly the National Nutrition Survey) has been conducted every year in Japan for the past 75 years. From its start and to the present, it has changed in order to focus on the public health issues of the time, which is the unique characteristic of this survey. Therefore, our aim is to sum...
Article
Objective: To describe the nutritional issues faced during the search for the "optimal diet" in modern Japan, how it evolved into the development of the current Dietary Reference Intakes, and its future perspectives for further health promotion. Methods: We investigated and summarized the history of the Dietary Reference Intakes in Japan, by review...
Article
Objective: In the dietary survey of the National Nutrition Survey (NNS) and National Health and Nutrition Survey (NHNS), which has been conducted for more than 70 years, the reference weight of food portion is indispensable for accurately assessing the dietary intake. Thus, we summarized the history of the food composition table and the food number...
Article
Full-text available
The relationship between free sugars intake and cardiometabolic risk factors is unclear in Japanese adults. This cross-sectional study aimed to investigate this association using data from the 2016 National Health and Nutrition Survey, Japan. The percentage of energy intake from free sugars was estimated based on the 1-day weighed dietary record da...
Article
Full-text available
The influence of free sugars intake on nutrient intake remains unclear in Japanese children and adolescents with relatively low free sugars intake. This cross-sectional study aimed to investigate the relationship between free sugars and selected nutrients intakes using data from the 2016 National Health and Nutrition Survey, Japan, based on the Wor...
Article
Full-text available
Background: Although assessing nutrient intake through dietary surveys is desirable, it can be effort- and time-intensive. We aimed to develop a brief screening method for determining sodium intake in order to raise public awareness regarding the Dietary Reference Intakes for Japanese (DRI-J) 2020. Methods: Using data from the 2015 National Heal...
Article
Full-text available
Few studies have reported association between sodium-to-potassium (Na-K) ratio and risk factors related to cardiovascular diseases (CVDs) among the general population in Asian countries. This study aimed to investigate the dietary sodium-to-potassium (Na-K) ratio association with CVD risk factors among Japanese adults. This retrospective cross-sect...
Article
Objective To investigate the relationship between nutrient intake and a straightforward Japanese nutritional goal of consuming a meal that includes staple, main and side dishes (SMS meal) more than twice a day. Design This was a cross-sectional, observational study using the data from de-identified records of the 2012 National Health and Nutrition...
Article
Objective To examine 44-year trends in height, weight and BMI, and the prevalence of overweight/obesity and underweight in the elderly Japanese population because Japan, the country with the longest life expectancy, has the highest ageing population. Design Using the nationally representative cumulative data from the Japan National Health and Nutr...
Article
Objective: Based on the provisions of Article 8 of the Health Promotion Act, each prefecture has established a "Prefectural Health Promotion Plan." In 2018, the government conducted an interim evaluation of Health Japan 21 (second term). However, the interim evaluation status of each prefectural health promotion plan is unknown. Accordingly, to des...
Article
Objective To examine nutrient and food intakes according to the levels of skeletal muscle mass index (SMI) in the elderly. Design Cross-sectional study. Setting Data were derived from the 2017 National Health and Nutrition Survey in Japan. SMI was calculated by dividing appendicular skeletal muscle (or lean) mass (kg) by height squared (m ² ). We...
Preprint
Full-text available
Background: Consumption of home-cooked meals may lead to better nutritional intake. Few studies have examined the effect of frequency of home-cooked meal consumption on inadequacy of nutritional intake based on nutritional standards. We therefore aimed to examine the association between the frequency of home-cooked meal consumption and nutrient int...
Preprint
Full-text available
Background: Consumption of home-prepared meals may lead to better nutritional intake. Few studies have examined the association between the frequency of consuming meals prepared away from home and the adequacy of nutritional intake based on nutritional standards. We therefore aimed to investigate this issue among Japanese adults. Methods: This stud...
Preprint
Full-text available
Background: Consumption of home-prepared meals may lead to better nutritional intake. Few studies have examined the association between the frequency of consuming meals prepared away from home and the inadequacy of nutritional intake based on nutritional standards and food group intake. We therefore aimed to investigate this issue among Japanese ad...
Article
Full-text available
Dietary intake of adequate quality and quantity in early life is essential for healthy growth and development. This study aimed to examine the association between one-year change in growth and diet quality in preschool children in Adachi City, Tokyo, Japan. A total of 110 participants (49% boys, four to five years old at baseline) were included in...
Article
Full-text available
The double burden of malnutrition (under- and overnutrition) is a serious public health issue in childhood. The mid-upper arm circumference (MUAC) is a simple tool for screening nutritional status, but studies of the optimal cutoff to define malnutrition are limited. This study aimed to explore the prediction of malnutrition by MUAC in Sri Lankan s...
Article
Objective: The Japanese National Health and Nutrition Survey (JNHNS) is conducted to estimate intakes of foods and nutrients among Japanese people. This study aimed to compare national nutrition surveys conducted in other countries to the JNHNS. Methods: Information on national nutrition surveys in Australia, Brazil, Canada, China, Finland, Germany...
Article
Full-text available
Objective Although several studies in Western countries show that higher socioeconomic status is associated with higher diet quality, no study has observed this association in Japan. In the current study, we examined the association between diet quality and the combinations of age, sex, and household income, and also compared the dietary intake bet...
Article
Lower birth weight is associated with a risk of type 2 diabetes in adulthood. However, it is not clear whether this association is modified by physical activity. This study aimed to examine the association between birth weight and glycemic status and whether this association is mediated by moderate- and vigorous-intensity activity (MVPA) in Japanes...
Article
Full-text available
Child malnutrition and maternal obesity are serious public health issues in Sri Lanka. This study explores the associations between socioeconomic status and the double burden of malnutrition among school-aged children and within their household. A total of 543 primary school children aged 5-10 years (204 boys and 339 girls) in Gampaha District, Sri...
Article
Full-text available
Consumption of dairy products in the usual diet may be important for improving the overall quality of dietary intake. This study aimed to assess the difference in nutrient intake adequacy according to the intake of dairy products based on a 1-day weighed dietary record of Japanese adults from the 2016 National Health and Nutrition Survey. Nutrition...
Article
Objective: To improve the "Cooking Courses for Men," which have been conducted for men for over 20 years in the suburbs of Tokyo, we conducted a questionnaire survey to determine the food attitudes and behaviors of participants. Methods: The "Cooking Courses for Men" was a living care prevention course series sponsored by the C Welfare Public Corpo...
Article
Objective Previous studies have associated dietary patterns with diabetes risk in Western countries, but such studies among the Japanese population are scarce. The present study aimed to investigate dietary patterns associated with abnormal glucose tolerance determined by elevated glycated Hb (HbA1c) levels. Design The 2012 National Health and Nut...
Article
Full-text available
Mid-to-late gestation is a unique period in which women experience dynamic changes in lipid metabolism. Although the recent intensive epigenome-wide association studies (EWAS) using peripheral leukocytes have revealed that lipid-related traits alter DNA methylation, the influence of pregnancy-induced metabolic changes on the methylation levels of t...
Article
To clarify the degree of consistency between the international recommendations and the national Japanese system, the nutrient reference values (NRVs) adopted by the CODEX were compared with current Japanese NRVs 2015, the dietary reference intakes for Japanese (DRIs-J) 2015, and actual nutrient intake levels by the Japanese population. The Japanese...
Article
This study aimed to identify the influence of revisions to the food composition database in Japan, on nutrient intake estimates using one-day food intake data from 26,133 participants of the National Health and Nutrition Survey, 2016. The nutrient profiles of food intakes were developed using two editions of the Japanese Standard Food Composition T...
Article
Full-text available
While previous studies have reported the association between food portion size and health outcomes, the association between food seasonings and blood pressure (BP) has not been clarified. This study aimed to investigate the association between the portion sizes of traditional Japanese seasonings and BP. Data on 25,738 Japanese participants (10,154...
Article
Background and objectives: Recent studies have analyzed dietary patterns to assess overall dietary habits, but there have been no studies of dietary patterns among the contemporary Japanese population nationwide. The objective of this study was to identify dietary patterns based on consumption of food items among Japanese adults, and to examine wh...
Article
Background and objectives: Little is known about the association between dietary patterns and cardiovascular disease risk factors among Japanese adults based on nationally representative data. This study aimed to explore the association between dietary patterns and hypertension or blood lipid profiles among Japanese people. Methods and study desi...