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September 1993 - present
Publications
Publications (92)
Background
Climate change, leading to more frequent and intense extreme weather events (EWEs), could significantly impact dengue transmission. However, the associations between EWEs and dengue remains underexplored in the Southeast Asia (SEA) region. We investigated the association between selected EWEs (i.e. heatwaves, extremely wet, and drought c...
Background
Aedes mosquitoes are the main vector of dengue infection, a global health threat affecting millions of people annually. Conventional prevention and control methods against dengue outbreaks have only achieved marginal success. Recognizing the complex issue at hand, a multilevel participatory approach is crucial. Thus, alternative strategi...
Objectives
To use a community-based participatory research (CBPR) design to explore local community behaviours and stakeholders’ challenges in engaging communities in dengue prevention behaviours in Hulu Langat, Selangor, Malaysia.
Design
This CBPR design in implementation comprised in-depth interviews (IDIs) and focus group discussions (FGDs). Th...
Penyelidikan selama 16 minggu telah dijalankan untuk menilai impak semburan Isi Padu Ultra-Rendah (ULV) minyak pati Piper aduncum ke atas populasi vektor di lapangan dengan sipermetrin berfungsi sebagai kawalan positif. Kedua-duanya dinilai terhadap sentinel dewasa yang diberi gula dan larva instar ke-3 Aedes aegypti di kawasan perumahan yang mewak...
This study investigated the depth of climate change and environmental education (CCEE) in the current syllabus implemented in Malaysia from the perspectives of teachers, which is an extension to a study entitled ‘Impact of Climate Change on Children: A Malaysian Perspective’. This qualitative study involved in-depth interviews with a pool of teache...
This study investigated the depth of climate change and environmental education (CCEE) in the current syllabus implemented in Malaysia from the perspectives of teachers, which is an extension to a study entitled ‘Impact of Climate Change on Children: A Malaysian Perspective’. This qualitative study involved in-depth interviews with a pool of teache...
The impacts of climate change and degradation are increasingly felt in Malaysia. While everyone is vulnerable to these impacts, the health and wellbeing of children are disproportionately affected. We carried out a study composed of two major components. The first component is an environmental epidemiology study comprised of three sub-studies: (i)...
Aedes mosquitoes were found to lay their eggs in the cryptic breeding sites. Eliminating cryptic and open breeding sites is essential in reducing dengue virus transmission. However, it is often challenging for health officers to assess these breeding sites which are usually missed during larval surveillance. The autodissemination approach may produ...
Background
Dengue is a significant public health issue that is caused by Aedes spp. mosquitoes. The current vector control methods are unable to effectively reduce Aedes populations and thus fail to decrease dengue transmission. Hence, there is an urgent need for new tools and strategies to reduce dengue transmission in a wide range of settings. In...
Dengue fever is a mosquito-borne disease, showing a significant impact on humans and increasing public health concern. However, existing vector control has failed to reduce dengue infections, indicating that the method may not be sufficient enough and need to be revised. Pyriproxyfen autodissemination is a novel strategy by manipulating mosquitoes...
The new emergence and re-emergence of arbovirus infections transmitted by Aedes mosquitoes have been spreading across Southeast Asia, Central Africa, United States, tropical Oceania and has become a major of public health concern. These arbovirus diseases were found to have a similar vector, symptoms, and environments. The situation is complex due...
The new emergence and re-emergence of arbovirus infections vectored by Aedes mosquitoes have been spread across Southeast Asia, Central Africa, United States, tropical Oceania and become a major of public health concerns. These arbovirus diseases found to have a similar vector, symptoms of the diseases and environments. The situation has become com...
In Malaysia, dengue fever is a common vector-borne disease. Most cases of dengue fever are reported in residential areas. Children are at high risk to be infected because they spend a lot of time around their housing area for outdoor activities. Such areas may have a high number of Aedes mosquitoes. As schools are equipped with infrastructure and m...
This is the first study to evaluate the efficacy of an autodissemination approach, as suggested by WHO. Therefore, the efficacy of an autodissemination approach in small-scale field trials against wild Aedes sp. population was evaluated in an urbanized setting, Malaysia. Lethal ovitraps enhanced with pyriproxyfen were used to control Aedes sp. popu...
In this paper, we will start off by introducing the classical Ross–Macdonald model for vector-borne diseases which we use to describe the transmission of dengue between humans and Aedes mosquitoes in Shah Alam, which is a city and the state capital of Selangor, Malaysia. We will focus on analysing the effect of using the Mosquito Home System (MHS),...
Dengue fever is endemic and remains a public health concern in Malaysia. The highest number of dengue cases occurred in Selangor in 2015. The majority of hotspot and outbreak areas in Malaysia were located in residential areas. Despite the high number of dengue prevalence in Malaysia, evidence for the level of community knowledge and practice of me...
Background: Dengue fever is endemic in Malaysia and continues to be a public health concern. Selangor was the top hit and there is a paucity of information on knowledge, attitudes, and practices (KAP) of Bandar Baru Bangi residents regarding dengue infection. Therefore, the objective of this study is to describe dengue related knowledge, attitudes...
Exposure to pesticides and fertilizers lowers the level of trace elements in the human body for several reasons. This study aimed to investigate the effect of pesticide exposure to the levels of trace elements of farmers in Bachok and Tumpat, Kelantan, Malaysia. This cross sectional study involved 89 farmers. Demographic data and information on the...
The essential oils of Litsea elliptica, Piper aduncum, and Piper sarmentosum were prepared as repellents in gel formulation, and their repellent properties against Aedes aegypti were experimentally investigated. The lowest effective doses against adult mosquitoes were 0.8%, 0.5%, and 0.4% for Lit. elliptica, P. sarmentosum and P. aduncum, respectiv...
TOP 10 Outstanding poster in 3rd Pan-Asian Biomedical Science Conference 2016
Background: One of the key requirements for accomplishing a mutual goal is the formation of partnerships. ‘Partnership’ is an ill-defined concept, subject to multiple interpretations and frequently used interchangeably with alliance, coalition, network and collaboration among other terms. World Health Organisation had emphasized dengue prevention a...
The control of mosquitoes is threatened by the appearance of insecticide resistance and therefore new control chemicals are urgently required. Here we show that inhibitors of mosquito peptidyl dipeptidase, a peptidase related to mammalian angiotensin-converting enzyme (ACE), are insecticidal to larvae of the mosquitoes, Aedes aegypti and Anopheles...
In recent times, several infectious and zoonotic diseases have emerged as major threats to the health of people and animals globally, resulting in suffering and death of human and animals. The One Health Manual, an initiative of Malaysia One Health University Network (MyOHUN), is the first local Manual to deal with zooneses outbreak investigation b...
Background:
Pesticide exposure possesses risk of genotoxicity to humans, particularly farmers. Despite accumulating evidences linking genotoxicity to pesticide exposure, epidemiological studies to address pesticide toxicity in occupationally exposed farmers in Malaysia remain underreported. Thus, this study was aimed to determine the presence of n...
Forensic entomology refers to the science of collection and analysis of insect evidence in order to determine the minimum time period since death. This study aimed to investigate the occurrence of forensically important flies on 34 human remains referred to Universiti Kebangsaan Malaysia Medical Centre over a period of three years. Entomological sp...
The essential oil (EO) of Piper aduncum Linnaeus, known as ‘sireh lada’ to locals Malaysian, has the potential to be used as an alternative to synthetic insect repellents such as N,N-diethyl-meta-toluamide. However, the EO's efficacy as a repellent decreases after application due to the high volatility of its active ingredients. A number of studies...
Objective: Given the increasing number of abandoned dead bodies found in high-rise buildings in Malaysia, a study was conducted to investigate the decomposition stages of the carcasses and the distribution of forensically important flies in a high-rise building in Malaysia. Methods: Two dead monkeys were exposed simultaneously, one was placed at th...
Agriculture is an important component of the Malaysian economy. Pesticides are widely used by farmers to increase crop production. Acetylcholinesterase (AChE) is known to play an important role in the degradation of acetylcholine (ACh) at the neuromuscular junction of the nervous system. The purpose of this study was to determine the effect of pest...
The distributions of flies are not only confined to ground level but can also be at higher altitudes. Here, we report three forensic cases involving dipterans in high-rise buildings in Kuala Lumpur, Malaysia. Case 1 involved a corpse of adult female found at the top floor of a fifteen-story apartment. Case 2 dealt with a body of a 75-year-old femal...
The uncontrolled use of insecticides has caused major problems including resistance of mosquito towards the insecticides, environmental pollution, and effects on non-target organisms. Therefore, the potential of bismuth(III) dithiocarbamate compounds to be developed as insecticides to overcome these problem was explored in this study. The aim of th...
Health awareness promotion among farming communities are important for a sustainable agriculture activities. A crosssectional study was conducted to assess health status among farming communities in Cameron Highlands, Pahang (n = 61) and Bachok and Pasir Puteh, Kelantan (n = 143). Mobile Health Screening Programme composed of assessment of blood gl...
Chromium is an essential mineral and cofactor for insulin that plays an important role as hormone that helps in the blood sugar regulation. Kelantanese were known as sugar-based food consumer. Farmers have high risk of health problem because of exposure to pesticide and sugar-based food intake can give an effect on the level of chromium. The object...
ABSTRAK Kromium merupakan mineral yang penting dan kofaktor insulin yang memainkan peranan penting sebagai hormon yang membantu dalam regulasi gula dalam darah. Penduduk Kelantan sering dikaitkan dengan pengambilan makanan berasaskan gula. Petani merupakan golongan yang berisiko tinggi kerana pendedahan terhadap pestisid dan pengambilan makanan ber...
Dengue is a major public health threat in Malaysia, which is known for the hyperendemicity with all the four serotypes of the dengue virus circulating concurrently. Annual dengue cases reported were 43,000 cases for 2013, and this imposed a heavy toll on the resources for dengue prevention and control program. The objective of mapping in our study...
The current study determined the prevalence of intestinal protozoan infections among the Orang Asli schoolchildren in Pos Senderut, Pahang, Malaysia. The overall intestinal protozoan infection rate was 85% (261 out of 307). The highest prevalence rates were due to Entamoeba coli (24.4%), Giardia lamblia (21.8%), Blastocystis hominis (21.2%) and Ent...
Chromium is an essential mineral and cofactor for insulin that play an important role as hormone that helps in the blood sugar regulation. Kelantanese were known as sweet food consumer. Farmers have high risk of health problem because of exposure to pesticide and sweet food intake can give an effect on the level of chromium. The objective of this r...
Dengue is a vector borne disease which is one of the major threats to public health in Malaysia. Mapping of dengue distribution in spatial and spatial-temporal aspects can be a useful method in assessing the risk of dengue to the community. This study aimed to map the spatial and spatial-temporal distribution of dengue cases in Seremban district. T...
Pesticide exposure can lead to low trace elements levels in human body. Trace element plays important role in body metabolism. The aim of this study was to study the levels of selenium, zinc and chromium among paddy farmers who expose to pesticide in Wilayah I, MADA, Perlis. This cross sectional study involved 70 males paddy farmers and 57subjects...
Social networking site Facebook is the latest online avenue for social interactions. Facebook commands a lot of popularity among the students. This study was conducted to determine the relationship between time spent on Facebook and the Cumulative Grade Point Average (CGPA) of third year Biomedical Science students in the Faculty Health Sciences, U...
Litsea elliptica Blume has been traditionally used to treat headache, fever, and stomach ulcer, and has also been used as an insect repellent. The acute and subacute toxicities of L. elliptica essential oil were evaluated orally by gavage in female Sprague-Dawley rats. For the acute toxicity study, L. elliptica essential oil was administered in dos...
Entamoeba histolytica and/or Entamoeba dispar is an intestinal protozoa that has a high prevalence of infection among the indigenous aboriginal community. It is widespread in tropical and subtropical areas and in developing countries compared with developed countries. A total of 111 fecal samples of aboriginal children from the Jahai tribe was scre...
Introduction: This study observed the pattern of reported dengue infections, clinical manifestations, and circulating dengue serotypes in Negeri Sembilan, Malaysia. The aim of this study is to determine the co-circulation of the four different dengue virus serotypes in Negeri Sembilan,
Methodology: We analysed the surveillance data (VEKPRO) from Ne...
To evaluate the effectiveness and residual effects of trypsin modulating oostatic factor-Bacillus thuringiensis israeliensis (TMOF-Bti) formulations against Aedes aegypti (Ae. aegypti) (L.) larvae at UKM Campus Kuala Lumpur.
Twenty first instar Ae. aegypti larvae were added in each bucket containing 4 L of water supplied with crushed dried leaf pow...
Heavy metals, particularly cadmium, lead, and arsenic, constitute a significant potential threat to human health. This study was conducted to determine the levels of cadmium, lead, and arsenic in nail samples from farmers at Muda Agricultural Development Authority (MADA), Kedah, Malaysia, and evaluate factors that can contribute to their accumulati...
A study on mosquito ecology is important in planning control activities for mosquitoe borne diseases. A study on Aedes ecology was conducted in Senawang, Negeri Sembilan from July 2009 to Febuary 2010. Senawang is located at the city fringe and is an industrial area for small and medium industries, with high population density. This study aims to d...
Dengue fever and dengue haemorrhagic fever have been on an increasing trend for the past two decades. The aim of this study is to determine the cost of illness as a result of dengue fever and dengue haemorrhagic fever. The research method is based on the calculation of cost of illness. Cost-of-illness is operationalized via direct and indirect cost...
AbStRAK entamoeba histolytica dan/atau entamoeba dispar merupakan protozoa usus yang mempunyai prevalens infeksi yang tinggi dalam kalangan masyarakat pedalaman terutamanya masyarakat Orang Asli. Ia tersebar secara meluas di kawasan tropika dan subtropika serta di negara membangun berbanding negara maju. Sebanyak 111 sampel feses kanak-kanak Orang...
Effective learning intervention should include early detection of problems in academic performance, strategies to help students develop better approaches for academic success and facilitation of self-directed learning. While the program incurred some hidden and indirect costs, the intervention can be significant, delivering the wanted result throug...
The bioefficacy of Piper aduncum L. essential oil formulated in aerosol cans was evaluated against Aedes aegypti and Aedes albopictus in a simulated room. The aerosol spray test was based on the Malaysian test standard for aerosol (MS 1221:1991UDC 632.982.2 modified from WHO 2009 methodology) and examined the knockdown effect within 20 minutes of e...
Trypsin Modulating Oostatic Factor (TMOF) terminates trypsin biosynthesis in adult and larval mosquito gut. It will inhibit the growth and development of mosquito larvae feeding on it resulting in death by starvation. The objective of this study is to determine the effective dose of Pichia-TMOF and the combination of Pichia-TMOF with Bacillus thuri...
Ovitrap surveillance was conducted in methodically selected areas in Bentong, Pahang, Malaysia from June 2008 till December 2009 in order to identify insular sites with stable Aedes aegypti population. Eleven sites were surveyed in Bentong district, Pahang, and one of these locations (N3º33' E101º54') was found to have an ovitrap index of Ae. aegyp...
A cross sectional study was carried out to examine the relationship between self –esteem and students' academic performance among the second year undergraduates of Faculty of Health Sciences and Faculty of Medicine, UKM session 2010/2011. Undergraduates (n= 220, 110 males) were selected via systemic random sampling, responded on survey domains rega...
Litsea elliptica Blume (Lauraceae), known as Medang pepijat in Malaysia. It has been proven to have promising insecticidal activities. L. elliptica essential oil was evaluated for its acute toxicity (14 days) by the oral route in Sprague-Dawley rats. In this study, acute oral toxicity of the essential oil using female Sprague-Dawley rats (10/group)...
This study was carried out in an oil palm plantation in Tanjung Sepat, Selangor in September 2007 by using pigs (Sus scrofa L.) as a carcass model in a forensic entomological research. A 2.5 month old pig (10 kg) which died naturally was hanged on a palm tree to observe the insect succession and decomposition stages. Observation was made for 16 day...
This paper reports six male undergraduate students living at a local university hostel who were infested with cat fleas (Siphonaptera Pulicidae Ctenocephalides felis felis) m February 2009 All of them suffered from maculopapular rashes and severe pruritus after the bites Investigation revealed the presence of a stray cat in the hostel building, fiv...
This paper reports the infestation of psocid, Liposcelis bostrychophila Badonnel (Psocoptera: Liposcelidae) in the insect museum at Medical Entomology Unit, Institute for Medical Research, Kuala Lumpur. These tiny organisms were recognized as museum insect pest and found frequently in the insect boxes containing mosquitoes, flies, cockroaches and b...