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Publications (26)
The hydro distilled essential oil from the freshly cut leaves and branches of Melaleuca alternifolia Cheel. grown in India was analyzed by capillary GC and GC-MS. The leaf oil was found to contain 33 components (99.5%) of which 21 were completely identified, 6 were tentatively identified while as one remained unknown. Quantitatively the oil was cha...
GC-MS Analysis of the volatile oil of Artemisia annua Linn. resulted in isolation of 39 components, 37 of which comprising 99.2% of total volatiles were completely identified. Quantitatively the volatile oil was characterized by 65.7% of monoterpenes and 27.3% of sesquiter-penes. 1,8-cineole (15.1%) was prominent component followed by α-terpineole...
The effect of administering an ethanol extract of Cyamopsis tetragonoloba. Linn. (Leguminosae) beans on blood glucose levels in normal and alloxan-induced diabetic rats was evaluated in this study. The ethanol extract of beans at 250 mg/kg body weight significantly reduced the blood glucose levels in alloxan-induced diabetic rats within 3 h of admi...
Two new ursane-type triterpenes, zizyphursolic acid (1), and isozizyphursolic acid (2), have been isolated from the roots of Zizyphus vulgaris. Lam. (syn: Z. sativa. Gaertn.; Z. mauritiana. Lamk.) and characterized as 18β.H-urs-20 (30)-en-3β.-ol-28-oic acid and 18β.H-urs-20 (30)-en-2α.-ol-28-oic acid, respectively. Their structures were elucidated...
A new δ-lactone containing triterpene, 4β-methylcholest-20-en-12a-ol-3β-olide, was isolated from Calendula officinalis Linn. flowers in addition to three known compounds, lanast-20(22)-en-3β-ol, stigmast-5,22-dien-3β-ol, and stigmast-5,24(28)-dien-3β-ol. Their structures were elucidated by spectroscopic (UV, IR, NMR, and MS) methods and chemical re...
This study analyzed the antidiabetic properties of an ethanol extract of the stem bark of Psidium guajava, an indigenous medicinal plant used to control diabetes in Indian System of Medicine. The anti-hyperglycaemic activity of this plant on blood glucose levels of normal, normal glucose loaded (OGTT) and alloxan-induced hyperglycaemic rats was eva...
An aqueous and alcoholic extract of the roots of Aralia cachemirica (Araliaceae) were evaluated for hypoglycemic activity in normal fasted and glucose induced hyperglycemic rats. The aqueous and alcoholic extracts at a dose of 250 mg/kg showed statistically significant (p < 0.01) hypoglycemic activity in glucose loaded animals however no effect was...
One new triterpenoid of oleanene-series, cornulacic acid acetate 1 along with oleanolic acid acetate has been isolated from the flowers of Calendula officinalis Linn. The structure of 1 has been established as 3β-acetoxy-olean-12-ene-27-oic acid on the basis of spectral data analysis and chemical reactions. IPC: Int.Cl. 7 A 61 K 35/00 The genus Cal...
An aqueous extract of Pterocarpus marsupium wood was screened for hypoglycemic activity on alloxan-induced diabetic rats. During both acute and sub-acute tests, the water extract, at an oral dose of 250 mg/kg, showed statistically significant hypoglycemic activity.
Objective: To evaluate the anti-hyperglycemic activity of alcoholic extract of Aralia cachemirica Decne roots. Materials and methods: The alcoholic extract of Aralia cachemirica was tested for anti-hyperglycemic activity on normal fasted, glucose loaded and alloxan induced diabetic rats. Blood glucose levels were evaluated at 0,1 and 3 h in normal...
Objective: To evaluate the anti-hyperglycemic activity of alcoholic extract of Aralia cachemirica Decne roots. Materials and methods: The alcoholic extract of Aralia cachemirica was tested for anti-hyperglycemic activity on normal fasted, glucose loaded and alloxan induced diabetic rats. Blood glucose levels were evaluated at 0,1 and 3 h in normal...
Objective: To evaluate the anti-hyperglycemic activity of alcoholic extract of Aralia cachemirica Decne roots. Materials and methods: The alcoholic extract of Aralia cachemirica was tested for anti-hyperglycemic activity on normal fasted, glucose loaded and alloxan induced diabetic rats. Blood glucose levels were evaluated at 0,1 and 3 h in normal...
Objective: To evaluate the immunomodulatory activities of ethanolic extract of Mangifera indica, L. cultivar Neelam fruit pulp. Materials and methods: in the present study, the alcoholic extract of fruit pulp of M. indica has been investigated for its effect on cell mediated and humoral components of the immune system in mice. Results: Administrati...
Effect of feeding orally the aqueous extract of beans of Cyamopsis tetragonoloba was investigated on fasting blood glucose levels in glucose loaded, normal and alloxan-induced diabetic rats and compared with gliclazide, a reference drug. The aqueous extract of beans at 250 mg/kg body wt significantly lowered blood glucose levels in alloxan-induced...
A lanostane-type triterpene, zizyphulanostane-21-oic acid, and a terpenic delta-lactone, zizyphulanostan-18-oic acid, have been isolated from the roots of Zizyphus vulgaris Lam. (syn. Z. sativa Gaertn., Z. mauritina. Lam.) and characterized as lanosta-25 (26)-en-9alpha-ol-21-oic acid and lanosta-25 (26)-en-22beta-ol-18-oic acid 3(19)-olide, respect...
A water extract of Psidium guajava leaves was screened for hypoglycemic activity on alloxan-induced diabetic rats. In both acute and sub-acute tests, the water extract, at an oral dose of 250 mg/kg, showed statistically significant hypoglycemic activity.
Objective: To evaluate the hypoglycemic activity of ethanol extract of Psidium guajava leaves. Materials and methods: The ethanol extract of leaves of Psidium guajava was tested for its hypoglycemic activity in alloxan-induced hyperglycemic Wistar rats. Results: In both acute and sub-acute tests, the ethanol extract, at an oral dose of 250 mg/kg, s...
Objective: To evaluate the anti-hyperglycemic activity of water extract of Psidium guajava stem bark. Materials and methods: The water extract of stem bark of Psidium guajava was tested for its hypoglycemic activity in normal glucose loaded and alloxan-induced hyperglycemic Wistar rats. Blood glucose levels were evaluated at intervals of 30 and 90...
For Abstract see ChemInform Abstract in Full Text.
A new oleanene-type triterpene, named betuloleanolic acid acetate and fernane-type triterpenes, namely betufernanediol A and betufernanediol B (isomers) have been isolated from the stem bark of Betula pendula. Their structures have been established as olean-12-en-3beta-ylacetate-29-oic acid, fern-22(29)-en-3beta,12beta-diol and fem-22(29)-en-3alpha...