Hester Eppinga- MD PhD
- Department of Dermatology at Erasmus MC
Hester Eppinga
- MD PhD
- Department of Dermatology at Erasmus MC
About
15
Publications
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Introduction
Current institution
Publications
Publications (15)
Background:
Anti-NMDA-receptor-encephalitis is a progressive autoimmune disease with significant mortality if left untreated.
Case description:
A 58-year-old man without previous psychiatric or neurologic history presented at the emergency department after brief loss of consciousness at work. Within a few hours, the patient developed acute neuro...
Background
The concurrent occurrence of gut and skin diseases has led to the postulation of the existence of a gut-skin axis in which gut microbiota is thought to contribute to extra-intestinal skin manifestations. A dysbiotic skin microbiome has been demonstrated in the chronic inflammatory skin disease hidradenitis suppurativa (HS), but it remain...
Background:
Psoriasis, psoriatic arthritis (PsA), and inflammatory bowel disease (IBD) are related inflammatory immune-mediated diseases, with considerable overlap. However, it is as yet unclear whether co-occurrence of these diseases affects disease course and characteristics of the individual complaints. The objective of this study was to identi...
Background
Psoriasis and inflammatory bowel disease (IBD) are chronic inflammatory diseases sharing similar pathogenic pathways. Intestinal microbial changes such as a decrease of bakers’ yeast Saccharomyces cerevisiae have been reported in IBD, suggesting the presence of a gut-skin axis.
Objective
To investigate whether the S. cerevisiae abundanc...
Supplementary text.
(DOCX)
Accumulation of intermediate metabolites of the tricarboxylic acid (TCA) cycle in tumor cells can cause epithelial-to-mesenchymal transition (EMT), although the exact mechanisms remain elusive. Recent studies show that the oncometabolite fumarate, which accumulates in fumarate hydratase-deficient renal cancers, confers tumor aggressiveness by causi...
Background and aims:
Psoriasis and Hidradenitis Suppurativa (HS) co-occur more often with Inflammatory Bowel Disease (IBD) than expected due to shared pathogenic and genetic features. It is known that IBD patients harbour an altered intestinal microbiome characterized by a depletion of Faecalibacterium prausnitzii and increase of Escherichia coli....
In past decades, gut microbiome perturbations appeared to play a role in the
development of several autoimmune diseases. Microbiome dysbiosis together with
genetic, lifestyle and/or diet factors may composedly affect the etiology of autoimmune
diseases. Studies about the role of the gut microbiome in psoriatic arthritis (PsA),
a chronic autoimmune...
Psoriatic arthritis is a chronic inflammatory joint disease, seen in combination with the chronic inflammatory skin disease psoriasis and belonging to the family of spondylarthritides (SpA). A link is recognized between psoriatic arthritis and inflammatory bowel disease (IBD). Environmental factors seem to induce inflammatory disease in individuals...
