Herve Platel

University of Caen Normandy | UNICAEN · UFR de Psychologie

Introduction Reminiscence therapy (RT), which engages individuals to evoke positive memories, has been shown to be effective in improving psychological well-being in older adults suffering from PTSD, depression, and anxiety. However, its impact on brain function has yet to be determined. This paper presents functional magnetic resonance imaging (fM...

A central question in understanding cognition and pathology-related cognitive changes is how we process time. However, time processing difficulties across several neurological and psychiatric conditions remain seldom investigated. The aim of this review is to develop a unifying taxonomy of time processing, and a neuropsychological perspective on te...

Resilience mechanisms can be dynamically triggered throughout the lifecourse by resilience factors in order to prevent individuals from developing stress-related pathologies such as posttraumatic stress disorder (PTSD). Some interventional studies have suggested that listening to music and musical practice after experiencing a traumatic event decre...

Background: Alzheimer’s disease (AD) and Korsakoff’s syndrome (KS) are two major neurocognitive disorders characterized by amnesia but AD is degenerative while KS is not. The objective is to compare regional volume deficits within the Papez circuit in AD and KS, considering AD progression. Methods: 18 KS patients, 40 AD patients (20 with Moderate A...

People with Alzheimer’s disease (PWAD) show preservation of remote memory for songs. However, our recent findings suggest that they may also be able to encode new musical stimuli, but only for non-verbal information. Here, we tried to assess whether verbal and musical features of unknown songs could be encoded after 8 days of exposures sessions wit...

A central question in understanding cognition and pathology-related cognitive changes is how we process time. However, time processing impairments across several neurological and psychiatric disorders remains seldom investigated, with no unified understanding. In this review, an international group of experts from different backgrounds (cognitive p...

Despite severe amnesia, some studies showed that Alzheimer Disease (AD) patients with moderate to severe dementia keep a consistent, but impoverished representation of themselves, showing preservation of the sense of identity even at severe stages of the illness. Some studies suggest that listening to music can facilitate the reminiscence of autobi...

Cognitive decline appears across aging. While some studies report beneficial effects of musical listening and practice on cognitive aging, the underlying neurobiological mechanisms remain unknown. This study aims to determine whether chronic (6 h/day, 3 times/week) and long-lasting (4-8 months) music exposure, initiated at middle age in rats (15 mo...

The effects of musical practice on cognition are well established yet rarely compared with other kinds of artistic training or expertise. This study aims to compare the possible effect of musical and theater regular practice on cognition across the lifespan. Both of these artistic activities require many hours of individual or collective training i...

Background: Encoding of new information is considered to be impossible in people with Alzheimer's disease (PWAD) at a moderate to severe stage. However, a few case studies reported new learning under special circumstances, especially with music. Objective: This article aims at clarifying PWAD's learning capacities toward unknown material under m...

Musical interventions are now largely supported by many national health agencies as pertinent nonpharmacological care in pathological aging. Particularly, in the context of neurodegenerative diseases, such as Alzheimer’s, the interest of these interventions is typically to allow, notably during the early stages of the disease, significant reduction...

Research in cognitive neurosciences has developed significantly and has enabled the mechanisms of neuroplasticity to be studied in order to understand the effect of music practice. In children, this research concerns mainly the impact of music learning in the setting of a music conservatory. Moreover, recent studies have also sought to measure the...

Through this review of 25 clinical and experimental works on long-term musical memories in Alzheimer's disease (AD) patients, we attempt to clarify the conceptual understanding of musical memories, identify their evolution across the stages of the pathology, and propose possible explanations concerning the neural and cognitive mechanisms that under...

Research in cognitive neurosciences has developed significantly and has enabled the mechanisms of neuroplasticity to be studied in order to understand the effect of music practice. In children, this research concerns mainly the impact of music learning in the setting of a music conservatory. Moreover, recent studies have also sought to measure the...

Research and care have improved a lot for persons with dementia (PWD) in France. However, most studies are essentially descriptive, and very few researches have focused on theoretical framework that may help understand and help their caregivers (CG). Yet, some approaches exist, and have proven to be efficient in other countries. The main interest o...

Las agnosias auditivas, la sordera verbal pura y la sordera cortical constituyen los trastornos de la percepción auditiva de origen cerebral relacionados con una lesión del hemisferio derecho, izquierdo o bilateral que afecta en la mayoría de los casos a la corteza temporal. Las amusias son agnosias auditivas especializadas para la música. El estud...

The hippocampus has classically been associated with episodic memory, but is sometimes also recruited during semantic memory tasks, especially for the skilled exploration of familiar information. Cognitive control mechanisms guiding semantic memory search may benefit from the set of cognitive processes at stake during musical training. Here, we exa...

Brain activity and structure are shaped by life experiences. This plasticity has often been demonstrated with different types of expertise by using functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). Experts showed domain-specific functional neural changes during completion of a task when compared to non-experts. However,...

Le agnosie uditive, la sordita verbale pura e la sordita corticale costituiscono i disturbi della percezione uditiva di origine cerebrale, in rapporto con una lesione dell’emisfero destro, sinistro o bilaterale che interessa, il piu delle volte, la corteccia temporale. Le amusie sono agnosie uditive specializzate per la musica. Lo studio di queste...

Mémoire et identité sont liées intrinsèquement. Dans la maladie d’Alzheimer où la mémoire est très altérée, les patients perdent-ils toute représentation cohérente d’eux-mêmes ?

Congenital amusia, a neuro-developmental disorder of music perception and production, has been associated to abnormal anatomical and functional connectivity in a right fronto-temporal pathway. To investigate whether spontaneous connectivity in brain networks involving the auditory cortex is altered in the amusic brain, we ran a seed-based connectiv...

Relations between sensory functions and Alzheimer's disease are still under-explored. To understand them better, the Fondation Médéric Alzheimer has brought together a multi-disciplinary expert group. Aristote's five senses must be enhanced by today's knowledge of proprioception, motor cognition and pain perception. When cognition breaks down, the...

Given that there may well be no significant advances in drug development before 2025, prevention of dementia-Alzheimer's disease through the management of vascular and lifestyle-related risk factors may be a more realistic goal than treatment. Level of education and cognitive reserve assessment in neuropsychological testing deserve attention, as we...

Relations between sensory functions and Alzheimer's disease are still under explored.To understand them better, theFondation MédfJricAlzheimer has brought together a multi-disciplinary expert group. Aristote's five senses must be enhanced by today's know ledge of proprioception, motor cognition and pain perception. When cognition breaks dawn, the p...

La question de l’existence de substrats cérébraux spécifiques à la musique n’est pas nouvelle. En neurologie, à la fin du 19e siècle, les premières observations de dissociations cliniques montrant des patients aphasiques sans trouble amusiques ou l’inverse, ont appuyé initialement l’idée de régions cérébrales dédiées spécifiquement à la fonction mu...

Because of permanent use-dependent brain plasticity, all lifelong individuals' experiences are believed to influence the cognitive aging quality. In older individuals, both former and current musical practices have been associated with better verbal skills, visual memory, processing speed, and planning function. This work sought for an interaction...

La prise en charge de la maladie d’Alzheimer repose sur une approche multidisciplinaire. Elle nécessite une prise en charge globale intégrant les traitements médicamenteux et non médicamenteux. Les interventions psycho-sociales concourent au maintien ou à la réhabilitation des capacités fonctionnelles, des fonctions cognitives et sensorielles, au m...

The aim of this study was to explore whether musical practice-related gray matter increases in brain regions are accompanied by modifications in their resting-state functional connectivity. 16 young musically experienced adults and 17 matched nonmusicians underwent an anatomical magnetic resonance imaging (MRI) and a resting-state functional MRI (r...

Brain plasticity allows the central nervous system of a given organism to cope with environmental demands. Therefore, the quality of mental processes relies partly on the interaction between the brain’s physiological maturation and individual daily experiences. In this review, we focus on the neural implementation of musical expertise at both an an...

Objectives: The aim of this overview is to present the developments of music therapy in France, its techniques, mechanisms and principal indications, mainly in the context of Alzheimer's disease. Methods: An international review of the literature on music therapy applied to Alzheimer's disease was conducted using the principal scientific search...

L'Art est une forme de mystère. Il habite l'humain depuis la nuit des temps sous toutes les latitudes et dans toutes les cultures. Cet ouvrage collectif réunissant chercheurs et cliniciens est le fruit d'un Forum de la Société de Neuropsychologie de Langue Française consacré à ce thème pour deux raisons. Tout d'abord, la nécessité de faire le point...

In Alzheimer patients with a solid musical background, isolated case-reports have reported the maintenance of remarkable musical abilities despite clear difficulties in their verbal memory and linguistic functions. These reports have encouraged a number of scientists to undertake more systematic studies which would allow a rigorous approach to the...

Musical practice and cerebral plasticity: Can musical expertise prevent from cognitive aging? The intelligence of an organism expresses itself, in particular, by its ability to understand the environment and cope with its requests. This function is subserved by the high plastic properties of the brain where the anatomy of areas responsible for our...

The ever-improving emergency care of those who have suffered serious cerebrovascular disease has shifted the treatment objective towards helping sufferers regain independence - meaning that there is an increased need to understand, manage and treat the residual deficits. The Behavioral and Cognitive Neurology of Stroke focuses on the diagnosis and...

Recognizing a musical excerpt without necessarily retrieving its title typically reflects the existence of a memory system dedicated to the retrieval of musical knowledge. The functional distinction between musical and verbal semantic memory has seldom been investigated. In this fMRI study, we directly compared the musical and verbal memory of 20 n...

Examples of stimuli used during the familiarity task. (0.38 MB MP3)

List of the musical excerpts used in the musical familiarity task. (0.07 MB DOC)

The development of musical skills by musicians results in specific structural and functional modifications in the brain. Surprisingly, no functional magnetic resonance imaging (fMRI) study has investigated the impact of musical training on brain function during long-term memory retrieval, a faculty particularly important in music. Thus, using fMRI,...

Semantic memory has been investigated in numerous neuroimaging and clinical studies, most of which have used verbal or visual, but only very seldom, musical material. Clinical studies have suggested that there is a relative neural independence between verbal and musical semantic memory. In the present study, “musical semantic memory” is defined as...

Musical semantic memory: contribution of clinical neuropsychology and functional neuroimaging data Neuropsychological clinical dissociations between musical and linguistic skills in brain damage patients suggest the view of an autonomous musical semantic memory. On the basis of these clinical observations, Isabelle Peretz et al. propose the existen...

Le agnosie uditive, la sordità verbale pura e la sordità corticale sono alterazioni della percezione uditiva di origine cerebrale in rapporto con una lesione dell’emisfero destro, sinistro o bilaterale che interessa, in genere, la corteccia premotoria. Le amusie sono agnosie uditive specializzate per la musica. Lo studio di queste sindromi richiede...

We tested whether the emergence of familiarity to a melody may trigger or co-occur with the processing of the concept(s) conveyed by emotions to, or semantic association with, the melody. With this objective, we recorded ERPs while participants were presented with highly familiar and less familiar melodies in a gating paradigm. The ERPs time locked...

Numerous functional imaging studies have examined the neural basis of semantic memory mainly using verbal and visuospatial materials. Musical material also allows an original way to explore semantic memory processes. We used PET imaging to determine the neural substrates that underlie musical semantic memory using different tasks and stimuli. The r...

By adapting methods of cognitive psychology to neuropsychology, we examined memory and familiarity abilities in music in relation to emotion. First we present data illustrating how the emotional content of stimuli influences memory for music. Second, we discuss recent findings obtained in patients with two different brain disorders (medically intra...

Recognizing a musical excerpt without necessarily retrieving its title typically reflects the existence of a memory system dedicated to the retrieval of musical knowledge. The functional distinction between musical and verbal semantic memory has seldom been investigated. In this fMRI study, we directly compared the musical and verbal memory of 20 n...

Cognitive procedural learning occurs in three qualitatively different phases (cognitive, associative, and autonomous). At the beginning of this process, numerous cognitive functions are involved, subtended by distinct brain structures such as the prefrontal and parietal cortex and the cerebellum. As the learning progresses, these cognitive componen...

Les agnosies auditives, la surdité verbale pure, la surdité corticale, constituent les troubles de la perception auditive d'origine cérébrale en rapport avec une lésion de l'hémisphère droit, gauche ou bilatérale affectant le plus souvent le cortex temporopariétal. Les amusies sont des agnosies auditives spécialisées pour la musique. L'étude de ces...

This article reviews how neuropsychology, in the French-speaking world, has evolved as a discipline focused on research, teaching and clinical work. The article targets the last 30 years as this corresponds to the time at which the Société de Neuropsychologie de Langue Française (French-Speaking Neuropsychological Society) was created. The review a...

This article reviews how neuropsychology, in the French-speaking world, has evolved as a discipline focused on research, teaching and clinical work. The article targets the last 30 years as this corresponds to the time at which the Société de Neuropsychologie de Langue Française (French-Speaking Neuropsychological Society) was created. The review a...

Résumé La prise d’informations sur le monde extérieur ou sur notre organisme repose sur les systèmes sensoriels et sensitifs qui assurent la détection et le codage des stimulations physiques et chimiques ainsi que l’acheminement du message codé vers différents étages du système nerveux central où il sera analysé.

Cognitive procedural learning is characterized by three phases (cognitive, associative, and autonomous), each involving distinct processes. We performed a behavioral study and a positron emission tomography (PET) activation study using the Tower of Toronto task. The aim of the behavioral study was to determine cognitive predictors for the length of...

Introduction Following strokes, disorders of auditory perception produced by lesions located in the territory of the internal carotid artery or of the vertebrobasilar system can be observed. These disorders were gathered in several different clinical forms, now conventional: auditory agnosia is defined as the impossibility of recognizing environmen...

Amusia is the impaired perception and performance of music due to brain lesions that do not affect motor or sensory skills. Amusia is usually associated with other neuropsychological disorders. We report an exceptional case of pure amusia of sudden onset in a professional choir conductor, following right-sided temporal planum infarction revealing i...

The distinction between episodic and semantic memory has become very popular since it was first proposed by Tulving in 1972. So far, very few neuropsychological, psychophysical, and imaging studies have related to the mnemonic aspects of music, notably on the long-term memory features, and practically nothing is known about the functional anatomy o...

Which is the degree of cognitive and functional independence between language and music? Since the end of the 19th century, the clinical observations in neuropsychology showed the existence of dissociations between the linguistic and the musical abilities. It is realistic to think that these two domains show common processes in their most simple ex...

Numerous functional imaging studies have shown that retrieval from semantic and episodic memory is subserved by distinct neural networks. However, these results were essentially obtained with verbal and visuospatial material. The aim of this work was to determine the neural substrates underlying the semantic and episodic components of music using f...

The authors present the unique nature of psychological intervention in neuropsychology and the organisation of neuropsychological studies in psychologists' courses in France.

For now well over a century, neuropsychologists have investigated the various components of auditory perception. The central disorders of this perception have been a topic of considerable interest, mainly through observations of auditory agnosia or amusia (selective loss of musical abilities). In a remarkable way, it was shown that the disorders of...

Using PET, subtraction and correlation analysis were jointly employed to determine the specific and complementary contributions of frontal and medial temporal regions to verbal episodic encoding and retrieval processes. Subtraction analysis highlighted prefrontal rCBF increases which were predominantly left-sided during intentional encoding and exc...