Helene Banoun

Helene Banoun
French Institute of Health and Medical Research | Inserm · Gustave Roussy

PhD
Independent researcher https://twitter.com/BanounHelene

About

112
Publications
301,354
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749
Citations
Introduction
I've been thinking about immunology for several years now, especially concerning viral infections. And also on the implications of the theory of evolution in the field of immunology.
Skills and Expertise
Additional affiliations
September 1982 - October 1986
French Institute of Health and Medical Research
Position
  • charge de recherches

Publications

Publications (112)
Presentation
Full-text available
Analisi del rapporto ANSM sul Beyfortus pubblicato il 30 settembre 2024 Helene Banoun https://orcid.org/0000-0001-8391-7989 Farmacista biologa, ex incaricato alla ricerca all’INSERM https://ansm.sante.fr/actualites/prevention-de-la-bronchiolite-du-nourrisson-les-premieres-donnees-de- pharmacovigilance-confirment-le-profil-de-securite-du-nirsevimab...
Presentation
Full-text available
Ce rapport concerne la première campagne d'immunisation au Beyfortus qui s'est déroulée entre septembre 2023 et avril 2024. Il analyse les données françaises et internationales. Le Beyfortus est un anticorps monoclonal destiné à protéger les nourrissons contre la bronchiolite à virus VRS. Ce rapport ANSM vient confirmer mon analyse de cette campagn...
Presentation
Full-text available
Analysis of the ANSM (French Pharmacovigilance Agency) report on Beyfortus published on September 30, 2024 Helene Banoun https://orcid.org/0000-0001-8391-7989 Pharmacist-biologist, former INSERM research fellow PHARMACOVIGILANCE INVESTIGATION REPORT EXPERTISE REPORT N°1 BEYFORTUS® (Nirsevimab) 09/11/2023 to 04/30/2024, published on September 30,...
Data
Traduction par l'auteur de la version peer-review Résumé Les infections respiratoires à VRS représentent une part importante des admissions à l'hôpital pour des infections respiratoires aiguës. Le nirsevimab a été développé pour réduire la charge hospitalière des infections à VRS (virus respiratoire syncytial) : par rapport au produit précédemment...
Article
Full-text available
Respiratory infections with respiratory syncytial virus (RSV) account for an important part of hospital admissions for acute respiratory infections. Nirsevimab has been developed to reduce the hospital burden of RSV infections. Compared with the product previously used, it has a stronger binding capacity to RSV F protein and a high affinity for FcR...
Preprint
Full-text available
Respiratory infections with RSV account for an important part of hospital admissions for acute respiratory infections. Nirsevimab has been developed to reduce the hospital burden RSV (respiratory syncytial virus) infections: Compared with the product previously used, it has a stronger binding capacity to RSV F protein and a high affinity for FcRn (...
Preprint
Full-text available
Abstract: Respiratory infections with RSV account for an important part of hospital admissions for acute respiratory infections. Nirsevimab has been developed to reduce the hospital burden RSV (respiratory syncytial virus) infections: Compared with the product previously used, it has a stronger binding capacity to RSV F protein and a high affinity...
Preprint
Full-text available
A new epidemic of avian influenza in wild birds has been detected since 2020, and is gathering momentum in 2023. Experts fear a possible human pandemic due to the 2.3.4.4 clade of the H5N1 virus. The CDC-US has identified 4 human cases among employees of dairies or poultry farms, but no serious cases. In the USA, both cows and milk are contaminated...
Preprint
Full-text available
Résumé Une nouvelle épidémie de grippe aviaire chez les oiseaux sauvages a été détectée depuis 2020 et elle prend de l'ampleur en 2023. Les experts craignent une possible pandémie humaine due au clade 2.3.4 .4 du virus H5N1. Le CDC-US recense 4 cas humains chez des employés de laiterie ou d'élevage de volailles mais aucun cas grave. Aux USA les vac...
Preprint
Full-text available
Abstract: Respiratory infections with RSV account for 1⁄4 of hospital admissions for acute respiratory infections. Nirsevimab has been developed to reduce the hospital burden of these infections: Since it has a long shelf life thanks to its high affinity for FcRn (neonatal receptor for the Fc fragment of IgG), it requires only a single injection an...
Preprint
Full-text available
Respiratory infections with RSV account for ¼ of hospital admissions for acute respiratory infections. Nirsevimab has been developed to reduce the hospital burden of these infections: Since it has a long shelf life thanks to its high affinity for FcRn (neonatal receptor for the Fc fragment of IgG), it requires only a single injection and can be adm...
Preprint
Full-text available
Summary To understand the origin of the Covid virus and the management of the resulting crisis, the virological approach is of course essential, but we also need to consider the concept of biopolitics, which can explain the apparent irrationality of the management of this pandemic. A historical approach is just as essential for understanding this c...
Preprint
Full-text available
Résumé Pour comprendre l'origine du virus de la Covid et la gestion de le crise qui en a résulté l'approche virologique est bien sûr indispensable mais il faut aussi utiliser le concept de biopolitique qui peut expliquer l'irrationalité apparente de la gestion de cette pandémie. L'approche historique est autant indispensable pour comprendre ce con...
Preprint
Full-text available
RÉSUMÉ J'ai fait ce travail pour répondre aux doutes de Pierre Chaillot sur le rôle exact du virus SARS- CoV-2 dans la maladie Covid-19. Ces doutes lui sont apparus lorsqu'il a analysé les données des tests de détection du virus depuis le début de 2020. Il ne voit pas de diffusion de l'épidémie dans les courbes représentant la positivité en fonctio...
Preprint
Full-text available
Last month, you may have read Hélène Banoun's article on the Beyfortus clinical trials, which showed an imbalance in deaths (some due to bronchiolitis) to the disadvantage of the treated group The molecular mechanism that could explain this facilitation/aggravation of bronchiolitis was proposed in the article. Well, less than 3 months after the s...
Data
RSV bronchiolitis vaccines and preventive therapies : efficiency and toxicity Monoclonal antibody preventive therapies? Some financial aspects of vaccines and monoclonal antibodies It is to be feared that this monoclonal antibody (Beyfortus), whose Fc fragment has been modified, could cause this dangerous ADE effect in certain infants, which woul...
Book
Full-text available
Loin du pseudo-consensus fabriqué pour étouffer les voix dissidentes, des chercheurs indépendants résistent aux nouveaux dogmes, dont la biologiste Hélène Banoun, qui, avec ce livre, traite des questions cruciales : d'où vient le virus SARS-CoV-2 ? Que sait-on vraiment de cette maladie ? Pourquoi cet acharnement du pouvoir à ne pas la soigner ? Que...
Data
The unpleasant surprises of RSV (respiratory syncytial virus) bronchiolitis vaccines and preventive therapies Monoclonal antibody preventive therapies? Some financial aspects of vaccines and monoclonal antibodies
Poster
Full-text available
Les mauvaises surprises des vaccins et thérapies préventives contre la bronchiolite à VRS Faut-il recommander le Beyfortus, anticorps monoclonal contre la bronchiolite des nouveau-nés? Quelques aspects financiers des vaccins et anticorps monoclonaux
Preprint
Full-text available
About the mechanisms and long-term follow-up of post-COVID mRNA injection myocarditis Abstract The biodistribution of nanoparticles containing mRNA vaccine and their inflammatory effect may explain post-vaccine myocarditis. Patients who have suffered from myocarditis require long-term follow-up, as they have a reduced life expectancy and increased...
Preprint
Full-text available
Every time a young vaccinated athlete dies, the media continues to claim that Covid infection causes more myocarditis than the vaccine. Yet all serious studies show the opposite. We have not seen the last of pseudo-studies and peremptory assertions by self-proclaimed specialists that the virus is more dangerous than the vaccine despite evidence to...
Preprint
Full-text available
La biodistribution des nanoparticules contenant le vaccin ARNm ainsi que leur effet inflammatoire peuvent expliquer les myocardites post-vaccinales. Les patients ayant souffert de myocardite doivent être suivi sur le long terme car ils ont une espérance de vie réduite et des risques cardio-vasculaires augmentés.
Preprint
Full-text available
Quels sont les risques réels de myocardite après infection Covid et après vaccin Covid? À chaque décès de jeune athlète vacciné les médias continuent d'affirmer que l'infection Covid cause plus de myocardites que le vaccin. Pourtant toutes les études sérieuses montrent le contraire. Je n’ai pris la peine de réfuter celles qui ont d’énormes biais et...
Method
Full-text available
Why request an autopsy after the death of a person vaccinated with a messenger RNA “vaccine” against COVID-19? “mRNA DISEASE” is a new inoculation pathology What examinations should be requested in order to establish the causal link between the injection and the death? (Translation of the French document) * In memory of Pr Arne BURKHARDT, histopath...
Data
Résumé : Les vaccins COVID-19 ont été développés et approuvés rapidement en réponse à l'urgence créée par la pandémie. Aucune réglementation spécifique n'existait au moment de leur mise sur le marché. Les agences réglementaires l'ont donc adaptée en fonction de l'urgence. Maintenant que l'urgence pandémique est passée, il est temps d'examiner les q...
Preprint
Full-text available
COVID-19 vaccines were developed and approved rapidly in response to the urgency created by the pandemic. No specific regulations existed at the time they were marketed. The regulatory agencies therefore adapted them as a matter of urgency. Now that the pandemic emergency has passed, it's time to consider the safety issues associated with this rapi...
Method
Full-text available
Quels examens autopsiques réclamer dans le cas où le vaccin anti-Covid-19 serait suspect d'avoir causé le décès ? Le document ci-dessous reprend le protocole d'une équipe allemande de pathologistes et a été complété par d'autres sources de la littérature scientifique [1]. Résumé Le mécanisme des effets indésirables des vaccins ARNm est rappelé...
Article
Full-text available
COVID-19 vaccines were developed and approved rapidly in response to the urgency created by the pandemic. No specific regulations existed at the time they were marketed. The regulatory agencies therefore adapted them as a ma er of urgency. Now that the pandemic emergency has passed, it is time to consider the safety issues associated with this rapi...
Preprint
Full-text available
Abstract: COVID-19 vaccines were developed and approved rapidly in response to the urgency created by the pandemic. No specific regulations existed at the time they were marketed. The regulatory agencies therefore adapted them as a matter of urgency. Now that the pandemic emergency has passed, it's time to consider the safety issues associated with...
Presentation
Full-text available
Selon les agences de santé (EMA, European Medicines Agency, FDA-US, Food and Drug Administration-US, OMS), les vaccins en général échappent à certains contrôles exigés pour les médicaments humains et ceci sans justification scientifique : ils ne sont pas généralement soumis à des études de pharmacocinétique par exemple sauf cas particulier. Cependa...
Preprint
Full-text available
The COVID-19 pandemic is no longer dramatically in the spotlight, but its management confirms and amplifies the directions biopolitics has taken for decades. Biopolitics is the politics of the population and concerns in particular in its sanitary aspect the preparation and the prevention of pandemics. Its result is now moving away from the intended...
Preprint
Full-text available
Comment le concept de biopolitique peut nous aider à comprendre la politique sanitaire mondialisée Résumé La pandémie COVID-19 n'est plus mise en avant au niveau spectaculaire mais sa gestion confirme et amplifie les orientations de la biopolitique depuis des dizaines d'années. La biopolitique est la politique de la population et concerne en partic...
Preprint
Full-text available
FDA Report: spontaneously collected adverse events for Pfizer BNT162b2 vaccine between December 11, 2020, and February 28, 2021 This is the report of adverse event reports from Pfizer's safety database until February 28, 2021: this database includes cases reported spontaneously by health authorities, in the medical literature, collected by Pfizer-f...
Preprint
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Rapport de la FDA : Effets indésirables du vaccin Pfizer BNT162b2 recueillis spontanément entre le 11 décembre 2020 et le 28 février 2021 [1] Il s'agit du compte-rendu des notifications d'effets indésirables de la base de données de sécurité de Pfizer jusqu'au 28 février 2021 : cette base données regroupe les cas rapportés spontanément par les auto...
Presentation
Full-text available
According to health agencies (EMA, European Medicines Agency, US-FDA, Food and Drug Administration-US, WHO), vaccines in general escape some of the controls required for human drugs and this without scientific justification: they are not generally subject to pharmacokinetic studies for example except in special cases. However, according to the EMA,...
Data
ARNm : vaccin ou thérapie génique ? Les enjeux de la réglementation. Résumé Les vaccins échappent à certains contrôles exigés pour les médicaments humains (sans justification scientifique). Les vaccins ARNm qui représentent une nouvelle classe de vaccin devraient cependant subir plus de contrôles que les vaccins classiques car ils sont fondés sur...
Preprint
Full-text available
Vaccines escape some of the controls required for human drugs (without scientific justification). However, mRNA vaccines, which represent a new class of vaccine, should be subject to more controls than conventional vaccines because they are based on several new technologies. Conventional vaccines could be replaced by mRNA vaccines and anti-cancer "...
Preprint
Full-text available
SOMMAIRE Myocardites (incidence et mécanismes) 5 Biopolitque (Que révèle la Covid-19 sur la biopolitique du XXIè siècle) 5 La FDA savait depuis février 2021 que le vaccin ARNm traverse le placenta, passe dans le lait et occasionne des effets indésirables chez le bébé allaité - Avril 2023 6 AUTOPSIES 7 Article collectif 7 Pourquoi demander une autop...
Article
Full-text available
Background. Messenger RNA (mRNA) vaccines have been widely used as the main sanitary measure destined to fight the COVID-19 pandemic. Rapidly purported as being “safe and effective”, this new generation of vaccines is radically different from those developed traditionally and for which potentially associated adverse events (AEs) are considered thro...
Preprint
Full-text available
What do the Moderna and Pfizer preclinical studies recently unveiled by FOIA reveal? Summary Definition and background: vaccines are based on the spike protein, which has long been known to be toxic. Coronavirus vaccines have been known since 2003 to cause ADE (Antibody Dependent Enhancement, i.e. facilitation of infection). Documents obtained by...
Preprint
Full-text available
mRNA vaccines: EMA and FDA regulations for gene therapy products Summary The anti-Covid mRNA vaccines are not subject to biodistribution and excretion studies and this according to the regulations of the health agencies. The European regulation is very vague. The same product may or may not be classified as a gene product depending on whether or no...
Preprint
Full-text available
Que révèlent les études précliniques Moderna et Pfizer dévoilées récemment par FOIA ? Résumé Définition et rappel : les vaccins sont fondés sur la protéine spike dont la toxicité est connue depuis longtemps. Les vaccins anti-coronavirus sont connus depuis 2003 comme susceptibles de provoquer l'ADE (facilitation de l'infection). Les documents obtenu...
Preprint
Full-text available
Pourquoi les vaccins ARN anti-Covid ne sont-ils pas soumis à des études complètes de pharmacocinétique? État de la réglementation. Résumé Les vaccins ARNm anti-Covid ne sont pas soumis aux études de biodistribution et d' excrétion et ceci en fonction de la règlementation des agences de santé. La règlementation européenne est très floue Un même pro...
Preprint
Full-text available
Background . Messenger RNA (mRNA) vaccines have been widely used as the main sanitary measure destined to fight the COVID-19 pandemic. Rapidly purported as being “safe and effective”, this new generation of vaccines is radically different from those developed traditionally and for which potentially associated adverse events (AEs) are considered thr...
Article
Full-text available
Abstract The massive COVID-19 vaccination campaign is the first time that mRNA vaccines have been used on a global scale. The mRNA vaccines correspond exactly to the definition of gene therapy of the American and European regulatory agencies. The regulations require excretion studies of these drugs and their products (the translated proteins). Thes...
Data
Abstract The massive COVID-19 vaccination campaign is the first time that mRNA vaccines have been used on a global scale. The mRNA vaccines correspond exactly to the definition of gene therapy of the American and European regulatory agencies. The regulations require excretion studies of these drugs and their products (the translated proteins). Thes...
Preprint
Full-text available
La campagne massive de vaccination contre le COVID-19 est la première utilisation de vaccins à ARNm à l'échelle mondiale. Les vaccins à ARNm correspondent exactement à la définition de la thérapie génique des agences réglementaires américaines et européennes. La réglementation exige des études d'excrétion de ces médicaments et de leurs produits (le...
Presentation
Full-text available
Résumé Les vaccins anti-COVID-19 utilisés sont tous fondés sur la spike ou la contiennent. Les vaccins reproduisent les effets pathogènes de la spike virale toxique La plupart des mécanismes biologiques qui expliquent les effets indésirables des vaccins ont été anticipés par des experts officiels ou non. La spike du SARS-CoV-2 interagit avec le sys...
Article
Full-text available
Children are less susceptible to COVID-19 than adults: they often have asymptomatic and very rarely severe forms. This protection is valid for all variants of the virus. The aim here is to compare the immune response of children with that of adults, asymptomatic adults or those with mild disease with those who develop severe Covid. Several protecti...
Preprint
Full-text available
Abstract Children are less susceptible to COVID-19 than adults: they often have asymptomatic forms and very rarely severe forms. This protection is valid for all variants of the virus. The aim here is to compare the immune response of children with that of adults but also that of asymptomatic adults or those with mild disease with those who develop...
Preprint
Full-text available
For the past 2 years, we have been told that mRNA vaccines are flexible and can be adapted rapidly to new circulating variants. Finally, there is talk of this adaptation for the fall of 2022, even though the virus has been mutating since it emerged. Why is this so late and what can we expect? What does the history of vaccines tell us about this wi...
Preprint
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Adaptation des vaccins COVID-19 pour l'automne 2022 On nous fait miroiter depuis 2 ans la souplesse des vaccins ARNm qui permet une adaptation rapide aux nouveaux variants circulants. Il est question finalement de cette adaptation pour l'automne 2022 alors que le virus mute depuis qu'il a émergé. Pourquoi est-ce si tardif et que peut-on en attendre...
Presentation
Full-text available
In the USA, the question of vaccination of children is absolutely crucial for vaccine manufacturers because the generalisation to minors automatically deviates the entire management of serious undesirable effects to the States, including for damages perpetrated in adults [*]. This Homeric American battle between independent and corrupt doctors will...
Conference Paper
Full-text available
Résumé Les enfants sont moins susceptibles à la COVID-19 que les adultes : ils font souvent des formes asymptomatiques et très rarement des formes sévères. Cette protection est valable pour tous les variants du virus. Il s'agit ici de comparer la réaction immunitaire des enfants avec celle des adultes mais aussi celle des adultes asymptomatiques ou...
Article
Full-text available
Antibody-dependent enhancement (ADE) is an inadequate response to reinfection or vaccination. ADE was described for influenza and dengue fever: patients already exposed are likely to develop a more severe infection when exposed to a virus of another type than the first. Vaccine antibodies also appear to be responsible for an increased risk of sever...
Article
Full-text available
La facilitation dépendante des anticorps (ADE) est une réponse inadéquate à la réinfection ou à la vaccination. L'ADE a été décrite pour la grippe et la dengue : les patients déjà exposés sont susceptibles de développer une infection plus sévère lorsqu'ils sont exposés à un virus d'un autre type que le premier. Les anticorps vaccinaux semblent égal...
Preprint
Full-text available
The non-natural origin of SARS-CoV-2 has been raised and discussed for the past 2 years. It is important to discuss it to understand the inflection of biopolitics since the 2000s. In addition, structural features of the virus, new compared to other known coronaviruses, may explain some aspects of the Covid-19 clinic and therapy. SARS-CoV-2 is the o...
Preprint
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L’origine non naturelle du SARS-CoV-2 a été évoquée et discutée depuis 2 ans. Il est important d’en parler pour comprendre l'inflexion de la biopolitique depuis les années 2000. De plus, des caractéristiques structurales du virus, nouvelles par rapport aux autres coronavirus connus, peuvent expliquer certains aspects de la clinique et de la thérape...
Presentation
Full-text available
Origins of SARS-CoV-2 Helene Banoun International Covid Summit, Marseille France Simultaneous translation https://www.bitchute.com/video/9f2hnef8xm6S/ French version https://crowdbunker.com/v/6GQSaZ41 (1h46’38’’) March 30, 2022
Preprint
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Résumé Deux publications récentes ont fait beaucoup de bruit car elles laissent penser que la rétrotranscription de l'ARN viral ou vaccinal et son intégration dans le génome humain ne sont pas totalement impossibles. La transformation (rétrotranscription) de l'ARN en ADN a été reconnue comme possible dès 1956 par Francis Crick et a été prouvée il y...
Preprint
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Abstract Knowing the origin of SARS-CoV-2 is important for understanding the inflection of biopolitics since the 2000s. In addition, the structural characteristics of the virus explain some aspects of the clinic and therapy. SARS-CoV-2 is the only human pathogenic coronavirus to possess a polybasic furin cleavage site and a human ACE2 binding site,...
Preprint
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Résumé L'origine du virus de la Covid-19 Il est important de connaître l'origine du SARS-CoV-2 pour comprendre l'inflexion de la biopolitique depuis les années 2000. De plus, les caractéristiques structurales du virus expliquent certains aspects de la clinique et de la thérapeutique. Le SARS-CoV-2 est le seul parmi les coronavirus pathogènes pour l...
Preprint
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Résumé Devant la menace d'un pass vaccinal en France et donc d'une obligation déguisée nombreux sont ceux qui attendent pour se soumettre à l'obligation l'arrivée des vaccins à virus inactivés qui seraient considérés comme plus classiques que les vaccins à ARNm. Sans discuter de l'intérêt actuel des vaccins Covid en général1, voici les données disp...
Preprint
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Un « Projet de loi renforçant les outils de gestion de la crise sanitaire NOR : PRMX2138186L/Rose-1 » sera déposé début janvier 2022 devant le parlement français. Il s'agit d'établir un passe vaccinal à la place du pass sanitaire. L'exposé des motifs est critiquable scientifiquement. Ce projet repose sur la supposée explosion des « cas » : ces cas...
Preprint
Full-text available
It is important to evaluate natural immunity against Covid-19: it is stronger, longer lasting and of better quality than vaccine immunity Only humoral (antibody) or cellular adaptive immunity can be assessed; innate immunity is not measurable. Serology is the only routine test, it is the measurement of the antibody level. The measurement of the a...
Preprint
Full-text available
Il est important d'évaluer l'immunité naturelle contre la Covid-19 : elle est plus solide, plus durable et de meilleure qualité que l'immunité vaccinale Seule l'immunité adaptative humorale (anticorps) ou cellulaire peut être évaluée ; l'immunité innée n'est pas mesurable. La sérologie est seule pratiquée en routine, c'est la mesure du taux d'antic...
Preprint
Full-text available
It should not be necessary to write an article to demonstrate the superiority of natural immunity over vaccine immunity, but it is necessary in view of the many underhanded attacks that tend to make artificial immunity seem more effective. Furthermore, it is officially recommended to vaccinate people who have already been infected with Covid-19. Su...
Preprint
Full-text available
Il devrait être inutile d'écrire un article pour démontrer la supériorité de l'immunité naturelle sur la vaccinale, mais cela devient nécessaire devant les nombreuses attaques sournoises qui tendent à faire passer l'immunité artificielle comme plus performante. De plus il est officiellement recommandé de vacciner les personnes qui ont déjà été infe...
Article
A growing body of evidence indicates that neutrophil elastase (NE) is involved in the pathogenesis of respiratory infectious diseases, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study aimed to analyze the dynamic changes in serum levels of NE associated with inflammation, disease activity, and mortality rate in patie...
Preprint
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Les vaccins Pfizer et Moderna viennent d'être autorisés en Europe pour les enfants à partir de 12 ans. L'EMA (Agence Européenne du Médicament) ne semble pas avoir la même appréciation que la FDA (Food and Drug Administration, USA) qui n'a pas autorisé Moderna aux USA. L'EMA et la FDA ne publient pas les mêmes chiffres bruts concernant l'efficacité...
Preprint
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Pfizer and Moderna vaccines just approved in Europe for children 12 years and older The EMA does not seem to have the same assessment as the FDA, which did not approve Moderna in the US. The EMA and the FDA do not publish the same raw numbers regarding the effectiveness of the Pfizer vaccine. Looking closely at the FDA data from the adolescent tria...
Article
Full-text available
The phenomenon of facilitation of viral infections by antibodies (ADE antibody dependent enhancement) as well as the resistance of agammaglobulinemia patients to certain viruses are in contradiction with the protective role of antibodies affirmed by classical immunology. This must be compared to the opsonizing antibodies that promote the specific p...
Conference Paper
Full-text available
Abstract Since the reporting of the first cases of coronavirus in China and the publication of the first sequence of SARS-CoV-2 in December 2019, the virus has undergone numerous mutations. In Europe, the spring outbreak (March–April) was followed by a drop in the number of cases and deaths. The disease may have evolved into a milder form. The incr...
Poster
Full-text available
About Evolution of SARS-CoV-2: review of mutations, role of the host immune system Banoun H, Nephron (2020) https://www.karger.com/Article/Abstract/515417 https://doi.org/10.1159/000515417 This article is part of Karger Editions COVID-19 topic article package (http://www.karger.com/Tap/Home/278492), where all articles are freely accessible. http...
Article
Full-text available
Since the reporting of the first cases of coronavirus in China and the publication of the first sequence of SARS-CoV-2 in December 2019, the virus has undergone numerous mutations. In Europe, the spring outbreak (March–April) was followed by a drop in the number of cases and deaths. The disease may have evolved into a milder form. The increase in P...
Article
Full-text available
The document associated with this DOI has been withdrawn.
Preprint
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J. et al. Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera. Nat Med 27, 620-621 (2021). https://doi. This publication by Pfizer employees attempts to show that the antibodies of people vaccinated with Pfizer's anti-Covid-19 vaccine are effective against the UK (B.1.1.7) and SA (B.1.351) v...
Article
Full-text available
It is important to evaluate natural immunity against Covid-19: it is stronger, longer lasting and of better quality than vaccine immunity only humoral (antibody) or cellular adaptive immunity can be assessed; innate immunity is not measurable. Serology is the only routine test, it is the measurement of the antibody level. The measurement of the ant...
Article
It should not be necessary to write an article to demonstrate the superiority of natural immunity over vaccine immunity, but it is necessary in view of the many underhanded attacks that tend to make artificial immunity seem more effective. Furthermore, it is officially recommended to vaccinate people who have already been infected with Covid-19. Su...
Preprint
The phenomenon of facilitation of viral infections by antibodies (ADE antibody dependent enhancement) as well as the resistance of agammaglobulinemia patients to certain viruses are in contradiction with the protective role of antibodies affirmed by classical immunology. This must be compared to the opsonizing antibodies that promote the specific p...
Preprint
Full-text available
Le phénomène de facilitation des infections virales par les anticorps ainsi que la résistance des patients aγglobulinémiques à certains virus sont en contradiction avec le rôle protecteur des anticorps affirmé par l 'immunologie classique. Ceci doit être rapproché des anticorps opsonisants qui favorisent la phagocytose spécifique des bactéries extr...
Preprint
Full-text available
The phenomenon of facilitation of viral infections by antibodies (ADE antibody dependent enhancement) as well as the resistance of agammaglobulinemia patients to certain viruses are in contradiction with the protective role of antibodies affirmed by classical immunology. This must be compared to the opsonizing antibodies that promote the specific p...
Preprint
Full-text available
Le phénomène de facilitation des infections virales par les anticorps ainsi que la résistance des patients aγglobulinémiques à certains virus sont en contradiction avec le rôle protecteur des anticorps affirmé par l 'immunologie classique. Ceci doit être rapproché des anticorps opsonisants qui favorisent la phagocytose spécifique des bactéries extr...
Preprint
Full-text available
Since the reporting of the first cases of Covid-19 in China and the publication of the first sequence of SARS-Cov-2 in December 2019, the virus has undergone numerous mutations and the disease may have evolved into a milder form. The increase in PCR positive cases in late summer 2020 did not lead to the expected increase in hospitalizations, ICU ad...
Preprint
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Dans un article datant de fin juin, j'essayais d'expliquer la perte de virulence apparente du SARS-CoV-2 par l'évolution du virus. Je rapporte ici les nouvelles observations qui viennent confirmer l'atténuation actuelle de la virulence du SARS-CoV-2. Je proposais que l'évolution du SARS-CoV-2 pouvait être mise en relation avec le système immunitair...
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In an article from the end of June, I tried to explain the apparent loss of virulence of SARS-CoV-2 by the evolution of the virus. I report here new observations that confirm the current attenuation of the virulence of SARS-CoV-2. I proposed that the evolution of CoV-2-SARSS can be related to the host immune system. This hypothesis was based on the...
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The low percentage of individuals in the population with symptomatic Covid-19 can be explained by cross-immunity with other coronaviruses. This phenomenon is based on cellular immunity. On the other hand, humoral immunity (antibody-mediated) could be partly responsible for some immunopathological phenomena. The balance between this beneficial cellu...
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Le faible pourcentage d'individus ayant développé une Covid-19 symptomatique dans la population peut s'expliquer par l'immunité croisée avec les autres coronavirus. Ce phénomène repose sur l'immunité cellulaire. L'immunité humorale (médiée par les anticorps) pourrait par contre être responsable en partie de certains phénomènes immunopathologiques....
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SUMMARY The low percentage of individuals in the population who developed symptomatic Covid-19 may be explained by cross-immunity with other coronaviruses. This phenomenon is based on cellular immunity. Humoral (antibody-mediated) immunity, on the other hand, may be partly responsible for some immunopathological phenomena. The balance between this...
Preprint
Full-text available
RÉSUMÉ Le faible pourcentage d'individus ayant développé une Covid-19 symptomatique dans la population peut s'expliquer par l'immunité croisée avec les autres coronavirus. Ce phénomène repose sur l'immunité cellulaire. L'immunité humorale (médiée par les anticorps) pourrait par contre être responsable en partie de certains phénomènes immunopatholog...
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ABSTRACT How can we explain the temporal evolution of the pandemic? An analysis of the curves of the epidemic at the late stage shows the evolution towards the benignity of the virus throughout the world. There is a prolonged increase in new cases with a steady decrease in severe cases and deaths. Cross-immunity with common cold coronaviruses has b...
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RÉSUMÉ Comment expliquer l'évolution temporelle de la pandémie ? Une analyse des courbes de l'épidémie au stade tardif montre dans le monde entier l'évolution vers la bénignité du virus. On observe une augmentation prolongée des nouveaux cas avec une baisse régulière des cas graves et des décès. Il a été suggéré une immunité croisée avec les corona...
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How can we explain the temporal evolution of the pandemic?The mutations in the viral RNA sequence observed in recent studies concern regions involvedin the interaction of the virus with cells of the host immune system. It therefore seems to be confirmed that the emerging virus has adapted to the host immune system by modifying its transmissibility...
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RÉSUMÉ Comment expliquer l'évolution temporelle de la pandémie ? Les mutations de la séquence de l'ARN viral observées dans de récentes études concernent des régions impliquées dans l'interaction du virus avec les cellules du système immunitaire de son hôte. Il semble donc se confirmer que le virus émergent s'est adapté au système immunitaire de so...
Conference Paper
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Association pour l’Etude de l’Evolution Biologique (A.E.E.B) CafÉvol : thème Exobiologie 26 octobre Compte rendu des interventions de Robert Pascal Louis Le Sergeant d’Hendecourt . Par Hélène Banoun Intervention de Louis Le Sergeant d'Hendecourt « Généricités, astrochimie, contingences, paradoxe de Fermi » De l'astrochimie à l'astrobiologie I...
Article
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Abstract How can we explain the temporal evolution of the pandemic? The mutations in the viral RNA sequence observed in recent studies concern regions involved in the interaction of the virus with cells of the host immune system. It therefore seems to be confirmed that the emerging virus has adapted to the host immune system by modifying its trans...

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